Clinical trials: CPAP, completed
Atrial Fibrillation, Obstructive Sleep Apnea
Prevention of Atrial Fibrillation After Coronary Artery Bypass Grafting in Patients With Obstructive Sleep Apnea
Background. Atrial fibrillation is one of the most common complications in the postoperative period of coronary artery bypass grafting (CABG) surgery and usually associated with increased length of hospital stay and higher…
- Conditions
- Atrial Fibrillation, Obstructive Sleep Apnea, Coronary Artery Bypass Grafting
- Trial name
- PAFOS (NCT02737215)
- Testing
- CPAP
- Where
- 3 sites in Brazil
- Volunteers
- 144 people
- Sponsor
- Rodrigo Pinto Pedrosa
Premature Neonate
Assessment of Ketamine and Propofol Sedation During LISA Method (Less Invasive Surfactant Administration)
Respiratory distress syndrome (RDS) caused by surfactant deficiency remains one of the major reasons of morbi-mortality in preterm infants and affects 85% of preterm babies born less than 32 week gestational age (wGA).
- Trial name
- ANALISA (NCT03705468)
- Where
- France
- Volunteers
- 71 people
- Sponsor
- University Hospital, Montpellier
Infant, Newborn, Infant, Low Birth Weight
Delivery Room CPAP in Extremely Low Birth Weight Infants
This pilot study was designed to determine the feasibility of randomizing extremely low birth weight (ELBW) infants <28 weeks' gestation who required resuscitation to one of two resuscitation methods, either: (a) 100% oxygen by…
- Conditions
- Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age, Infant, Premature
- Trial name
- DR-CPAP (NCT01223274)
- Testing
- CPAP/PEEP, Standard management practices
- Where
- 6 sites in United States
- Volunteers
- 104 people
- Sponsor
- NICHD Neonatal Research Network
Continuous Positive Airway Pressure, Hypoxia
Positive Pressure at Induction of Anesthesia in Children
SCENARIO: Hypoxemia is one of the most common adverse events during the induction of general anesthesia and may culminate with more serious complications such as cardiac arrest and death.
- Conditions
- Continuous Positive Airway Pressure, Hypoxia, General Anesthesia
- Trial name
- NCT03432390
- Testing
- Continuous Positive Airway Pressure, Open system ventilation
- Where
- Brazil
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Instituto Materno Infantil Prof. Fernando Figueira
Parkinson's Disease, Obstructive Sleep Apnea
Cognition and Obstructive Sleep Apnea in Parkinson's Disease, Effect of Positive Airway Pressure Therapy
Cognitive dysfunction (impaired memory, thinking, etc) frequently occurs in Parkinson's disease (PD), often progresses to dementia, and profoundly affects quality of life.
- Trial name
- COPE-PAP (NCT02209363)
- Testing
- auto-adjusting positive airway pressure, Nasal dilator strips
- Where
- 3 sites in Canada
- Volunteers
- 91 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Sleep Apnea
Telemonitoring in CPAP Treatment
Wireless telemonitoring was used during the habituation phase of continuous positive airway pressure (CPAP) treatment in obstructive sleep apnoea (OSA) patients.
- Trial name
- TeleCPAP (NCT02509247)
- Testing
- Telemonitoring
- Where
- Finland
- Volunteers
- 111 people
- Sponsor
- Turku University Hospital
Obstructive Sleep Apnea (OSA)
Weekly Phone Calls Versus Brief Patient Education to Improve CPAP (Continuous Positive Airway Pressure) Compliance
The purpose of this study is to compare the effects of three interventions on CPAP adherence.
- Trial name
- NCT00945776
- Testing
- Weekly phone calls, Frequently asked questions, Usual care
- Where
- United States
- Volunteers
- 128 people
- Sponsor
- CAMC Health System
OSA, Obstructive Sleep Apnea
Combination Drug-Therapy for Patients With Untreated Obstructive Sleep Apnea
Obstructive sleep apnea (OSA) is common and associated with many adverse health consequences, but many patients are unable to tolerate standard therapies such as continuous positive airway pressure (CPAP) and thus remain…
- Trial name
- RESCUE-Combo (NCT04639193)
- Testing
- Acetazolamide, Eszopiclone, Venlafaxine
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- University of California, San Diego
Obstructive Sleep Apnea, Non-alcoholic Fatty Liver Disease
Obstructive Sleep Apnoea and CPAP Treatment Response in Patients With Non-alcoholic Fatty Liver Disease
To study the frequency of obstructive sleep apnea (OSA) and continuous positive airway pressure (CPAP) treatment response in patients with non-alcoholic fatty liver disease (NAFLD).
- Trial name
- NCT02728765
- Testing
- Continuous positive airway pressure (CPAP)
- Where
- Hong Kong
- Volunteers
- 120 people
- Sponsor
- Chinese University of Hong Kong
Respiratory Distress Syndrome, Hyaline Membrane Disease
Weaning Preterm Neonates From Nasal Continuous Positive Airway Pressure
There is little data published concerning the best approach to nasal continuous positive airway pressure (nCPAP) weaning. Potential complications associated with prolonged nCPAP therapy include gastric distension, nasal…
- Conditions
- Respiratory Distress Syndrome, Hyaline Membrane Disease, Preterm Infants, Premature Infants
- Trial name
- NCT01093495
- Testing
- CPAP, Nasal Cannula
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Mansoura University
Acute Respiratory Distress Syndrome
Stepwise Positive End Expiratory Pressure Elevation For Lung Recruitment in Acute Respiratory Distress Syndrome (ARDS)
Acute respiratory distress syndrome is a severe lung disease caused by a variety of direct and indirect issues. It is characterized by inflammation of the lung parenchyma leading to impaired gas exchange and persistent hypoxemia.
- Trial name
- NCT01373905
- Testing
- Recruitment maneuver
- Where
- Egypt
- Volunteers
- 24 people
- Sponsor
- University of Alexandria
Obstructive Sleep Apnea, Masked Hypertension
Masked Hypertensive Patients With Obstructive Sleep Apnea
The general objective is to evaluate the effect of continuous positive airway pressure (CPAP) treatment in patients with masked hypertension.
- Trial name
- Masked-OSA (NCT04251975)
- Testing
- CPAP treatment
- Where
- Spain
- Volunteers
- 16 people
- Sponsor
- Sociedad Española de Neumología y Cirugía Torácica
Obstructive Sleep Apnea
Mediterranean Diet/Lifestyle Intervention in Obstructive Sleep Apnea
Obstructive sleep apnea (OSA) is a sleep disorder characterized by recurrent episodes of partial or complete collapse of the upper airway during sleep, leading to pauses of breathing and arousals.
- Trial name
- NCT02515357
- Testing
- Mediterranean lifestyle, Standard care, Mediterranean diet
- Where
- Greece
- Volunteers
- 187 people
- Sponsor
- Harokopio University
Obstructive Sleep Apnea
The Effectiveness of SensAwake™ for Continue Positive Airway Pressure Treatment of Obstructive Sleep Apnea Patients
This study will investigate Obstructive Sleep Apnea (OSA) and an automatically Adjusting Positive Airway Pressure (APAP) device with new technology called SensAwake™.
- Trial name
- NCT03294629
- Testing
- SensAwake™ modification
- Volunteers
- 35 people
- Sponsor
- Chang Gung Memorial Hospital
Respiratory Distress Syndrome, Newborn
Comparison of Methods of Weaning From Nasal CPAP in Preterm Infants: A Randomized Controlled Trial
This study aimed to determine the efficacy of different NCPAP weaning strategies in pre-term infants presenting with respiratory distress, and ultimately establishing the best method to withdraw from NCPAP.
- Trial name
- NCT07009366
- Testing
- Sudden weaning of NCPAP, Gradual weaning with increasing the time off NCPAP, Pressure weaning of NCPAP
- Where
- Pakistan
- Volunteers
- 75 people
- Sponsor
- RESnTEC, Institute of Research
Obstructive Sleep Apnea
Face of Sleepiness
The purpose of this pilot study is to find out whether successful treatment of obstructive sleep apnea makes people look less sleepy, for example by reducing swelling or dark circles under the eyes.
- Trial name
- Face (NCT01060436)
- Testing
- CPAP or BiPAP machines
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Michigan
Obstructive Sleep Apnea
Targeted CPAP Therapy for Obstructive Sleep Apnea in Pregnancy
Prospective, randomized controlled trial. Pregnant women in early pregnancy will be randomized to either the Sleep Study + CPAP (Continuous Positive Airway Pressure Therapy) group or to a Standard Prenatal Care group.
- Trial name
- NCT02755831
- Testing
- CPAP, Pre-natal care
- Where
- United States
- Volunteers
- 193 people, healthy volunteers welcome
- Sponsor
- United States Naval Medical Center, San Diego
Preterm Birth
Effect of Early Use of Caffeine Citrate in Preterm Neonates
This work is designed to study the effect of the early use of caffeine citrate in preterm neonates who need respiratory support on morbidity and short term neonatal outcome.
- Trial name
- NCT04001712
- Testing
- Caffeine Citrate
- Where
- Egypt
- Volunteers
- 54 people
- Sponsor
- Ain Shams University
Obesity, Obstructive Sleep Apnea
Obstructive Sleep Apnea-induced Changes in Adipose and Liver Tissue and Effects of Massive Weight Loss on Inflammation
UPDATED May 2016: Originally the study design included investigation of the effects of the bioactive compound resveratrol compared to placebo tablets and to CPAP treatment.
- Trial name
- NCT02419092
- Where
- Denmark
- Volunteers
- 27 people
- Sponsor
- University of Aarhus
Premature Birth
Changes in Respiratory Effort in Preterm Infants
Continuous Positive Airway Pressure (CPAP) is used to treat preterm infants with an immature respiratory center and having respiratory distress. CPAP requires intensive care monitoring and special qualified staff.
- Trial name
- NCT02014493
- Testing
- High Flow Nasal Cannulae (HFNC), Continuous Positive Airway Pressure (CPAP)
- Where
- Norway
- Volunteers
- 21 people
- Sponsor
- St. Olavs Hospital