Clinical trials: CPAP
Hypercapnic Respiratory Failure, Chronic Obstructive Pulmonary Disease
Non-invasive Ventilation Versus Sham Ventilation in Chronic Obstructive Pulmonary Disease (COPD)
The investigators hypothesize that continuation of non-invasive ventilation (NIV) at home after an episode of acute hypercapnic respiratory failure (AHRF) treated by NIV in COPD patients would reduce the likelihood of death and…
- Trial name
- NCT00429156
- Testing
- Home non-invasive ventilation
- Where
- Hong Kong
- Volunteers
- 46 people
- Sponsor
- United Christian Hospital
Prematurity, Respiratory Distress Syndrome, Newborn
Will CPAP Reduce Length Of Respiratory Support In Premature Infants?
In Canada each year, there are approximately 800 infants born between 28 and 32 weeks gestation. Up to 60% of these infants will require breathing tube placement for Respiratory Distress Syndrome or RDS.
- Trial name
- OLIVIA (NCT00486395)
- Testing
- CPAP, Mechanical ventilation
- Where
- 6 sites in Canada
- Volunteers
- 126 people
- Sponsor
- Children's & Women's Health Centre of British Columbia
Respiratory Failure, Sedation
Effects of NIV and CPAP on Ventilation Distribution, Measured by EIT, During Deep Sedation in Paediatric Patients
In patients undergoing spontaneous breathing (SB) deep sedation there is a re-distribution of ventilation towards lungs non-dependant areas (ventral areas in supine position).
- Conditions
- Respiratory Failure, Sedation, Mechanical Ventilation Complication
- Trial name
- NIVEIT-ped (NCT05495477)
- Testing
- EIT
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Dementia, Sleep Apnea
Effect of Treating Sleep Apnea on Cognition in Patients With Dementia
The purpose of this study is to determine whether treating sleep apnea with continuous positive airway pressure would result in improvements in cognition in patients with Alzheimer's disease.
- Trial name
- NCT00477828
- Testing
- Continuous positive airway pressure
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Obstructive Sleep Apnea
Effect of CPAP Treatment in Cognition in Adults With DS and OSA
Adults with Down syndrome (DS) have a high prevalence of obstructive sleep apnea (OSA), which may worsen cognitive performance. In general population, continuous positive airway pressure (CPAP), the gold Standard treatment for…
- Trial name
- NCT04198493
- Testing
- CPAP, CONSERVATIVE TREATMENT for OSA
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Parkinson's Disease, Obstructive Sleep Apnea
Cognition and Obstructive Sleep Apnea in Parkinson's Disease, Effect of Positive Airway Pressure Therapy
Cognitive dysfunction (impaired memory, thinking, etc) frequently occurs in Parkinson's disease (PD), often progresses to dementia, and profoundly affects quality of life.
- Trial name
- COPE-PAP (NCT02209363)
- Testing
- auto-adjusting positive airway pressure, Nasal dilator strips
- Where
- 3 sites in Canada
- Volunteers
- 91 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Atrial Fibrillation Paroxysmal, Atrial Fibrillation, Persistent
Value of Screening and Treatment of SAHS in the Management of AF Ablation Candidates
The present prospective cohort study (not randomized) analyses the value of screening and treatment of SAHS in the management of patients with AF refractory to antiarrhythmics drugs, potentially candidates for ablation.
- Conditions
- Atrial Fibrillation Paroxysmal, Atrial Fibrillation, Persistent, Apnea Syndrome, Hypopnea Syndrome
- Trial name
- SLEEP-AF (NCT04606693)
- Testing
- Treatment of SAHS
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Hospital San Carlos, Madrid
Obstructive Sleep Apnea Syndrome, Nasal Obstruction
Heated Humidified Continuous Positive Airway Pressure and Nasal Physiology
Nasal continuous positive airway pressure can cause nasal side effects which can compromise compliance to therapy. Humidifiers can attenuate this effect.
- Trial name
- NCT00850876
- Where
- Greece
- Volunteers
- 20 people
- Sponsor
- University of Athens
Neonatology
EXTERNAL NEGATIVE PRESSURE DURING LISA
The goal of this clinical trial is to evaluate the feasibility, safety, and preliminary effectiveness of applying external continuous negative pressure (ECNP) during less invasive surfactant administration (LISA) in preterm…
- Trial name
- ENCP LISA (NCT07271368)
- Testing
- ENCP
- Where
- Czechia
- Volunteers
- 25 people
- Sponsor
- Charles University, Czech Republic
Sleep Apnea, Breathing Disorder During Sleeping
Sleep Apnea in Paralympic Ontario-Resident aThletes With Spinal Cord Injury (SPORTS) Study
This single arm clinical trial will assess whether continuous positive airway pressure (CPAP) therapy in the management of moderate-to-severe sleep-related breathing disorders (SRBDs) among para-athletes living with…
- Conditions
- Sleep Apnea, Breathing Disorder During Sleeping, Sleep Disorder, Spinal Cord Injuries
- Trial name
- NCT06195878
- Testing
- CPAP Therapy
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- University Health Network, Toronto
Non-invasive Electrical Cardiometry
Prospective Evaluation of Electrical Cardiometry for Hemodynamic Monitoring in COPD Patients Admitted to the Respiratory Intensive Care Unit
This study investigates the reliability and clinical usefulness of non-invasive electrical cardiometry (ICON® device) in monitoring hemodynamic changes in COPD patients admitted to the respiratory intensive care unit (RICU).
- Trial name
- NCT07208578
- Volunteers
- 96 people
- Sponsor
- Assiut University
Early CPAP Ventilation in COVID-19 Patients
Early CPAP in COVID-19 Patients With Respiratory Failure. A Prospective Cohort Study.
This cohort study aims at prospectively collecting detailed clinical information on patients positive to or suspected of COVID-19 visiting Italian emergency departments (EDs). The objectives of the study are: 1.
- Trial name
- EC-COVID-PCS (NCT04323878)
- Where
- Italy
- Volunteers
- 6,000 people
- Sponsor
- Mario Negri Institute for Pharmacological Research
Ventilation Therapy; Complications, Diaphragm Disease
Real-time Effort Driven VENTilator Management
This study is a Phase II controlled clinical trial that will obtain comprehensive, serial assessments of respiratory muscle strength and architecture to understand the evolution of ventilator-induced respiratory muscle weakness…
- Conditions
- Ventilation Therapy; Complications, Diaphragm Disease, Pediatric Respiratory Diseases
- Trial name
- REDvent (NCT03266016)
- Testing
- Computerized Ventilator Protocol, Esophageal Manometry, Respiratory Inductance Plethysmography (RIP)
- Where
- United States
- Volunteers
- 248 people
- Sponsor
- Children's Hospital Los Angeles
Nasal Continuous Positive Airway Pressure
White Noise in Nasal Cpap Application
The aim of this study is to determine the effect of white noise application on the pain and stress level of newborns receiving oxygen support via nasal CPAP in the Neonatal Intensive Care Unit.
- Trial name
- NCT05440669
- Testing
- white noise
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Ataturk University
Chronic Obstructive Pulmonary Disease
Continuous Positive Airway Pressure Effect on Air Trapping in Chronic Obstructive Pulmonary Disease Patients
Chronic obstructive pulmonary disease is a disease characterized by small airways inflammation and obstruction. The small airways disease produces hyperinflation (air trapping), which increases with exercise.
- Trial name
- CPAP (NCT01507844)
- Testing
- positive ventilation
- Where
- Israel
- Volunteers
- 24 people
- Sponsor
- Assaf-Harofeh Medical Center
Sleep Apnea, Obstructive
The CPAP Effect in Severe Obstructive- Sleep- Apnea Patients Without Daytime Sleepiness: A Control Randomized Trial
Specific Aim: 1. To prove our hypothesis that in severe OSA patients without daytime sleepiness, CPAP worked as effectively as in severe OSA patients with daytime sleepiness.
- Trial name
- NCT00491088
- Testing
- CPAP
- Where
- Taiwan
- Volunteers
- 96 people
- Sponsor
- National Taiwan University Hospital
Preterm Birth, Premature
Comparison of the Acute Effects of Chest Physiotherapy Methods Applied in Different Positions in Preterm Newborns
Infants in the neonatal intensive care unit (NICU) may be lost due to risks such as being sensitive, frequent exposure to birth complications and being prone to infection.
- Conditions
- Preterm Birth, Premature, Bronchopulmonary Dysplasia, Respiratory Distress Syndrome
- Trial name
- therapy (NCT05036603)
- Testing
- chest physiotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Sanko University
Stroke, Acute, Obstructive Sleep Apnea
Continuous Positive Airway Pressure on Acute Stroke and Obstructive Sleep Apnea
Stroke affects 16.9 million individuals each year and is the second leading cause of death worldwide. Despite advances in pharmacologic therapy, morbidity , mortality and rates of hospitalization for stroke remain high.
- Trial name
- NCT04458779
- Testing
- CPAP
- Where
- Taiwan
- Volunteers
- 71 people
- Sponsor
- Far Eastern Memorial Hospital
Postoperative Period, Physical Therapy Modalities
Positive Pressure Therapy to Optimize LUNG Function After Heart Surgery
The most common cardiac surgeries are myocardial revascularization and valve replacement or plastic surgery. In the postoperative period of cardiac surgeries, the incidence of pulmonary complications ranges from 30% to 50% and is…
- Conditions
- Postoperative Period, Physical Therapy Modalities, Continuous Positive Airway Pressure, Respiratory Function Tests
- Trial name
- PRO-LUNGHS (NCT06611527)
- Testing
- PS+PEEP group, CPAP group
- Where
- Brazil
- Volunteers
- 156 people
- Sponsor
- Federal University of São Paulo
Covid19, Obstructive Sleep Apnea
Early Application of Continuous Positive Airway Pressure in Coronavirus Patients at Risk of Obstructive Sleep Apnea
This was an experimental clinical trial, Aim: To evaluate the role of early use of Continuous Positive Airway Pressure (CPAP) in management of moderate to severe Coronavirus disease 2019 patients at risk of Obstructive Sleep…
- Conditions
- Covid19, Obstructive Sleep Apnea, CPAP Ventilation, Corona Virus Infection
- Trial name
- NCT05934916
- Testing
- CPAP ( Continuous positive airway pressure), oxygen therapy
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Mansoura University
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