Clinical trials: CPAP
Severe Acute Cardiogenic Pulmonary Edema
CPAP Versus Bilevel Pressure Support Ventilation in Cardiogenic Pulmonary Edema
To evaluate whether bilevel positive airway pressure more rapidly improves ventilation than continuous positive airway pressure (CPAP) in patients with acute pulmonary edema.
- Trial name
- NCT00213681
- Testing
- Boussignac CPAP - bilevel ventilation support
- Where
- France
- Sponsor
- University Hospital, Rouen
Acute Hypoxemic Respiratory Failure, High-Flow Nasal Oxygen Therapy
Effects of Face Mask Continuous Positive Airway Pressure Vs. Noninvasive Ventilation Vs. High-flow Nasal Oxygen on Intubation-free Survival in Acute Hypoxemic Respiratory Failure: the TRIPOD Randomized Clinical Trial
Acute hypoxemic respiratory failure (AHRF) is a common indication for admission to an intensive care unit (ICU), with mortality exceeding 50% in cases where invasive mechanical ventilation is needed.
- Conditions
- Acute Hypoxemic Respiratory Failure, High-Flow Nasal Oxygen Therapy, Noninvasive Ventilation, Continuous Positive Airway Pressure (CPAP)
- Trial name
- TRIPOD (NCT06795971)
- Testing
- Continuous Positive Airway Pressure, High-flow nasal oxygen, Non-invasive ventilation
- Where
- China
- Volunteers
- 1,300 people
- Sponsor
- Southeast University, China
Obstructive Sleep Apnea of Adult
Impact of Intermittent Hypoxia on the Function of the Phagocytes
Patients with treatment-naive obstructive sleep apnea (OSA) who need continuous positive airway pressure (CPAP) therapy on clinical basis are included as well as healthy controls without OSA.
- Trial name
- NCT03618719
- Where
- Taiwan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Obesity Hypoventilation Syndrome
Target Volume Mode Controlled Ventilator in Obesity Hypoventilation Syndrome
The purpose of this study is to investigate the evolution of daytime partial pressure of carbon dioxide in the blood (PaCO2) after 6 weeks of noninvasive ventilation-pressure support ventilation (NIV-PSV) with target volume…
- Trial name
- OVO (NCT01104610)
- Testing
- Breas Vivo 40
- Where
- 2 sites in France
- Sponsor
- Breas Medical S.A.R.L.
Obstructed Sleep Apnea Syndrome in Patient Candidate to Baratric Surgery
Ketogenic Diet and CPAP Previous Bariatric Surgery
Obstructive Sleep Apnea Syndrome (OSAS) and obesity tend to coexist and are often associated with arterial hypertension, dyslipidaemia, and insulin resistance [1].
- Trial name
- NCT03791242
- Testing
- Cpap and ketogenic diet
- Where
- Italy
- Volunteers
- 66 people
- Sponsor
- University of Roma La Sapienza
Obstructive Sleep Apnea, Adverse Effects
Comparison of Nasal Positive End Expiratory Pressure Valve to Dental Device as an Alternative Treatment for Obstructive Sleep Apnea
Determine the clinical efficacy in terms of Apnea Hypopnea Index (AHI), excessive daytime sleepiness (EDS), nocturnal oxygenation of a nasal Positive end-expiratory pressure (PEEP) valve "Provent" in obstructive sleep apnea.
- Trial name
- NCT01553383
- Testing
- nasal peep valve "Provent"
- Where
- Hong Kong
- Volunteers
- 200 people
- Sponsor
- Chinese University of Hong Kong
Infant, Premature, Diseases, Bronchopulmonary Dysplasia
A Trial of Infant Flow Biphasic Nasal Continuous Airway Pressure (NCPAP) Versus Infant Flow NCPAP for the Facilitation of Extubation in Infants </= 1250 Grams
The purpose of this study is to compare two methods of delivering Nasal Continuous Airway Pressure (NCPAP): Biphasic Mode and a continuous mode, to see which is better in getting babies off the ventilator and decreasing lung…
- Conditions
- Infant, Premature, Diseases, Bronchopulmonary Dysplasia, Apnea of Prematurity
- Trial name
- NCT00308789
- Testing
- Biphasic Infant flow NCPAP, CPAP
- Where
- Canada
- Volunteers
- 136 people
- Sponsor
- Mount Sinai Hospital, Canada
Sleep Apnea, Hypertension
Spanish Cohort for the Study of the Effect of CPAP in Hypertension (CEPECTA)
AIMS:To know the effects of the treatment with nasal positive continuous airway pressure (CPAP) on systemic blood pressure and the expression of biological mediators, in systemic hypertension of recent diagnostic, whose have an…
- Trial name
- NCT00202527
- Testing
- Nasal continuos positive airway pressure
- Where
- Spain
- Volunteers
- 340 people
- Sponsor
- Sociedad Española de Neumología y Cirugía Torácica
OSA - Obstructive Sleep Apnea
SMARTPHONE APPLICATION HOME-BASED EXERCISES IN OBSTRUCTIVE SLEEP APNEA IN JEDDAH
The study aim is to explore the effects of a home-based exercise training smartphone application on sleep quality, fatigue, functional capacity, and quality of life among obstructive sleep apnea (OSA) patients in Jeddah city…
- Trial name
- NCT06954974
- Testing
- CPAP device, CPAP device and exercise, Exercise
- Volunteers
- 60 people
- Sponsor
- King Abdulaziz University
RDS of Prematurity
Sustained Lung Inflation With CPAP in Preterm Neonates (SI-CPAP)
Neonatal respiratory distress syndrome (RDS) is the most common cause of respiratory failure in the first few days in life. It is characterized by the tendency of alveoli and terminal bronchioles to collapse due to the lack of…
- Trial name
- SI-CPAP (NCT03916523)
- Testing
- Sustained lung inflation, Continuous positive airway pressure (CPAP), Mechanical ventilation
- Volunteers
- 100 people
- Sponsor
- Ain Shams University
Upper Airway Obstruction
Safety Study of Positive Airway Pressure Via a Nasal Mask in Obese Patients
Upper airway obstruction (UAO) is a frequently occurring complication during induction of general anesthesia. The American Society of Anesthesiologist (ASA) closed claim analysis of anesthesia complications indicate that a…
- Trial name
- NCT01627925
- Testing
- nasal mask and continuous positive airway pressure
- Where
- United States
- Sponsor
- Massachusetts General Hospital
Apnea, Infant, Premature
Randomized Trial of Nasal Continuous Positive Airway Pressure or Synchronized Nasal Ventilation in Premature Infants.
Very premature infants uniformly do not have mature functioning lungs to breathe well nor mature regulation mechanisms to breathe regularly. Assistance with a mechanical respirator is common.
- Conditions
- Apnea, Infant, Premature, Bronchopulmonary Dysplasia
- Trial name
- NCT00188968
- Testing
- Nasal Continuous Positive Airway Pressure, Synchronized Nasal Positive Pressure Ventilation
- Where
- 2 sites in Canada
- Volunteers
- 48 people
- Sponsor
- University of Manitoba
Obstructive Sleep Apnea, Excessive Daytime Sleepiness
BF2.649 in Patients With OSA, Still Complaining of EDS and Refusing to be Treated by CPAP.
Multicenter randomized double blind study versus placebo during 12 weeks with at first, an escalating dose period followed by stable dose period at the selected dose.
- Trial name
- HAROSA2 (NCT01072968)
- Testing
- BF2.649
- Where
- France
- Volunteers
- 268 people
- Sponsor
- Bioprojet
Respiratory Distress Syndrome in Premature Infant
Surfactant Therapy Via Supraglottic Airway to Preterm Neonates With RDS in Vietnam
Preterm babies often have trouble breathing because their lungs are not fully developed. This condition is called respiratory distress syndrome (RDS). A medicine called surfactant helps their lungs open up and work better.
- Trial name
- NEOSURF (NCT07098910)
- Testing
- Surfactant Administration Through Laryngeal or Supraglottic Airways (SALSA), Intubation - Surfactant administration - Extubation (INSURE)
- Where
- Vietnam
- Volunteers
- 440 people
- Sponsor
- Karolinska Institutet
Obstructive Sleep Apnea
Sleep Apnea Intervention for Cardiovascular Disease Reduction
Moderate to severe sleep apnea (a high number of breathing pauses on a sleep study) is a common health problem that is often associated with loud snoring and sleepiness.The medical term for this problem is obstructive sleep apnea…
- Trial name
- BestAIR (NCT01261390)
- Testing
- Conservative Medical Therapy (CMT), Active PAP with RT Support (Active-Beh), Active PAP with Behavioral Modification (Active+Beh)
- Where
- United States
- Volunteers
- 169 people
- Sponsor
- Brigham and Women's Hospital
Lung Disease, Undergoing Thoracosocpic Surgery
Nondependent Lung Ventilation and Fluid Responsiveness
The stroke volume variation (SVV), measured using the Vigileo-FloTrac system (Edwards Lifescience, Irvine, CA), has been shown to able to predict fluid responsiveness during one-lung ventilation (OLV) in patients undergoing…
- Trial name
- NCT02191410
- Testing
- High Frequency Positive Pressure Ventilation, Continuous Positive Airway Pressure
- Where
- Saudi Arabia
- Volunteers
- 62 people
- Sponsor
- Imam Abdulrahman Bin Faisal University
Obstructive Sleep Apnea
Investigative Headgear With CPAP Mask
This investigation is designed to evaluate the at-home usability, performance, user acceptance and reliability of the Headgear with a CPAP Mask for a duration of 2-4 weeks.
- Trial name
- NCT02323035
- Testing
- Headgear
- Where
- New Zealand
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Fisher and Paykel Healthcare
Normotensive, Obstructive Sleep Apnea
Normotensive OSA Patients With Nondipper Circadian Blood Pressure Pattern
The principal objective is to evaluate the effect of CPAP treatment on blood pressure (BP) in normotensive patients with nondipper circadian pattern with sleep apnea-hypopnea syndrome (SAHS).
- Trial name
- Nondipper-OSA (NCT03987425)
- Testing
- CPAP treatment
- Where
- Spain
- Volunteers
- 64 people
- Sponsor
- Sociedad Española de Neumología y Cirugía Torácica
Infant, Newborn, Infant, Low Birth Weight
Delivery Room CPAP in Extremely Low Birth Weight Infants
This pilot study was designed to determine the feasibility of randomizing extremely low birth weight (ELBW) infants <28 weeks' gestation who required resuscitation to one of two resuscitation methods, either: (a) 100% oxygen by…
- Conditions
- Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age, Infant, Premature
- Trial name
- DR-CPAP (NCT01223274)
- Testing
- CPAP/PEEP, Standard management practices
- Where
- 6 sites in United States
- Volunteers
- 104 people
- Sponsor
- NICHD Neonatal Research Network
Covid19, Hypoxemia
Evaluation of a Low-cost CPAP Device on Hospitalized COVID-19 Patients
The aim of this study is to evaluate the preliminary safety and performance of a low-cost locally-made Venturi-based Non-invasive Positive Pressure Ventilator (NIPPV) device for hypoxemic COVID-19 patients.
- Trial name
- OxyJet-CPAP (NCT04681859)
- Testing
- High Flow Nasal Oxygen (HFNO) treatment, Continuous Positive Airway Pressure (CPAP) therapy using OxyJet
- Where
- Bangladesh
- Volunteers
- 45 people
- Sponsor
- Bangladesh University of Engineering and Technology
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