Clinical trials: CPAP, completed
Obstructive Sleep Apnea
Transcend Auto vs Commercially Available Device Clinical Evaluation for Treatment of Obstructive Sleep Apnea (OSA)
The purpose of this study is to determine whether the Transcend Auto is as effective in treating obstructive sleep apnea as another device that is already on the market.
- Trial name
- NCT01799265
- Testing
- Somnetics Transcend Auto, Respironics REMstar Auto with C-Flex
- Where
- 3 sites in United States
- Volunteers
- 41 people
- Sponsor
- Somnetics International, Inc.
Obesity, Obstructive Sleep Apnea (Moderate to Severe)
Heated Humidified High Flow Nasal Cannula Oxygen in Obstructive Sleep Apnea in Adolescents
The research study is being done to test heated humidified high-flow air (HHF), as a treatment for OSA.
- Conditions
- Obesity, Obstructive Sleep Apnea (Moderate to Severe), Central Sleep Apnea
- Trial name
- NCT05354401
- Testing
- HHF
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- The Hospital for Sick Children
Sleep Apnea, Obstructive
Evaluation of Self-efficacy as a Predictor for CPAP-compliance in a OSAS-patients French Cohort
Continuous positive airway pressure (CPAP) is the reference treatment for obstructive sleep apnea syndrome (OSAS) and is effective in improving symptoms of OSAS, reducing risk of accidents and improving quality of life.
- Trial name
- SAFES (NCT05053581)
- Testing
- Survey
- Where
- France
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bordeaux
Obesity, Obstructive Sleep Apnoea Syndrome
Study of Eating Behaviour and Sense of Taste Before and After Treatment With Nocturnal Continuous Positive Airway Pressure in Overweight Patients With Obstructive Sleep Apnea Syndrome.
Obstructive sleep apnea (OSA) is characterized by a repeated partial or complete obstruction of the airway that results in a intermittent hypoxia and sleep disturbance.
- Trial name
- GOUSAS (NCT03701737)
- Testing
- questionnaires, wrist actimeter, Blood samples
- Where
- France
- Volunteers
- 94 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Obstructive Sleep Apnea
Oral Appliance Therapy in Obstructive Sleep Apnea
The aim of the study was to compare the effects of a mandibular advancement device (MAD) with those of nasal continuous positive airway pressure(nCPAP) and of an intra-oral placebo device in obstructive sleep apnea (OSA)…
- Trial name
- NCT00950495
- Testing
- Mandibular Advancement Device (MAD), nasal CPAP
- Where
- Netherlands
- Volunteers
- 64 people
- Sponsor
- VU University of Amsterdam
COVID-19, Respiratory Failure With Hypoxia
Elmo Respiratory Support Project - COVID-19
The number of COVID-19 cases has been growing exponentially, so that the industrialized economies are facing a significant shortage in the number of ventilators available to meet the demands imposed by the disease.
- Trial name
- NCT04470258
- Testing
- ELMO PROJECT AT COVID-19: STUDY IN HUMANS, ELMO PROJECT AT COVID-19: PROOF OF CONCEPT AND USABILITY
- Where
- Brazil
- Volunteers
- 10 people
- Sponsor
- Escola de Saúde Pública do Ceará
Human Immunodeficiency Virus, Obstructive Sleep Apnea
Obstructive Sleep Apnea Endotypes and Impact on Phenotypes of People Living With HIV
The investigators seek to understand how the different underlying causes of OSA affect the way people living with HIV (PLWH) experience OSA.
- Trial name
- PLWH/OSA (NCT03575143)
- Where
- United States
- Volunteers
- 132 people
- Sponsor
- University of California, San Diego
Sleep Apnea, Obstructive Sleep Apnea
Zonisamide for the Treatment of Obstructive Sleep Apnea in Overweight/Obese Patients
This RCT explores the efficacy of Zonisamide (Zonegran®)on overweight/obese in patients with moderate to severe obstructive sleep apnea.
- Conditions
- Sleep Apnea, Obstructive Sleep Apnea, Obesity
- Trial name
- NCT01765608
- Testing
- Zonisamide, nCPAP
- Where
- Sweden
- Volunteers
- 50 people
- Sponsor
- Göteborg University
Non-obstructive Hypertrophic Cardiomyopathy, Obstructive Hypertrophic Cardiomyopathy
Effects of Continous Positive Airway Pressure (CPAP) in Hypertrophic Cardiomyopathy
Hypertrophic cardiomyopathy (HCM) is the most common genetic cardiac disease, is a cause of disability including heart failure, atrial fibrillation, and sudden death, with an annual mortality varying from 1% to 6%.
- Trial name
- CPAPandHCM (NCT01631006)
- Testing
- CPAP
- Where
- Brazil
- Volunteers
- 26 people
- Sponsor
- University of Sao Paulo
Sleep Apnea, Obstructive
The Induction of IL-6 by NF-kB in PBMC in OSA
Aim of study: 1. To compare the level of IL-6 mRNA expression in peripheral blood monocytes between normal subjects and patients with OSAS 2.
- Trial name
- OSA (NCT00498381)
- Testing
- CPAP
- Volunteers
- 20 people
- Sponsor
- National Taiwan University Hospital
Diaphragmatic Paralysis
Comparison of Ultrasound with Fluoroscopy to Assess Diaphragmatic Paralysis After Congenital Heart Disease Surgery
Diaphragmatic paralysis after congenital heart disease (CHD) surgery can increase patient mortality and morbidity, especially for the vulnerable pediatric patient.
- Trial name
- USG vs Fluoro (NCT06766045)
- Testing
- Diaphragmatic Ultrasound, Fluoroscopy
- Where
- Indonesia
- Volunteers
- 41 people
- Sponsor
- National Cardiovascular Center Harapan Kita Hospital Indonesia
Infant, Newborn, Infant, Premature
Determining an Optimal Weaning Method of Nasal Continuous Positive Airway Pressure in Preterm Neonates
The purpose of this study is to determine an optimal strategy to wean nasal continuous positive airway pressure (NCPAP) in preterm babies.
- Trial name
- NCT02064712
- Testing
- Low CPAP Wean, High CPAP Wean
- Where
- United States
- Volunteers
- 226 people
- Sponsor
- University of Texas Southwestern Medical Center
Obesity, Obstructive Sleep Apnea
Treatment of Obstructive Sleep Apnea in Children: An Opportunity for Cardiovascular Risk Modification
Heart disease is a major cause of ill-health and death in adults. The risk factors for heart disease, if present in children, carry over into adult life.
- Conditions
- Obesity, Obstructive Sleep Apnea, Sleep Disorders, Cardiovascular Disease
- Trial name
- TREAT (NCT02403492)
- Testing
- cPAP, cPAP, Continuation, cPAP, Discontinuation
- Where
- Canada
- Volunteers
- 59 people
- Sponsor
- The Hospital for Sick Children
Sleep Apnea, Obstructive
Study of Provent Treatment of Obstructive Sleep Apnea in Patients Who Are Non-compliant With CPAP
The primary objective of the proposed investigation is to evaluate the efficacy of the Provent device in a sample of OSA patients who have either refused or been non-adherent with PAP treatment.
- Trial name
- NCT00901771
- Testing
- Provent
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- St. Luke's Hospital, Chesterfield, Missouri
Obstructive Sleep Apnea (OSA)
Improved Automatic CPAP Algorithm to Treat Obstructive Sleep Apnea (OSA)
The purpose of this study is to compare a modified AutoSet algorithm running on research hardware versus the traditional AutoSet algorithm running on an S7 AutoSet Spirit.
- Trial name
- NCT00850434
- Testing
- Modified AutoSet Algorithm, Standard AutoSet Algorithm
- Where
- Australia
- Volunteers
- 20 people
- Sponsor
- ResMed
Sleep Apnea Syndromes
Apnoea-Hypopnoea-Indices Determined Via Continuous Positive Airway Pressure vs Those Determined by Polysomnography
To date, no published systematic review and meta-analysis has compared AHI-CPAPflow and AHI-PSGgold. Therefore, the primary objective of this study is to compare published data for AHI-PSGgold and AHI-CPAPflow in patients treated…
- Trial name
- Meta IAHflow (NCT04526366)
- Testing
- Continuous Positive Airway Pressure, Polysomnography
- Where
- France
- Volunteers
- 1 people
- Sponsor
- University Hospital, Montpellier
OSA - Obstructive Sleep Apnea
OSA Patients' and Bed-Partners' Illness Perceptions in CPAP Therapy Adaptation Process
This study explores how psychological and relationship factors influence the success of CPAP therapy in people with Obstructive Sleep Apnea (OSA) and their partners.
- Trial name
- CPAP-IPA (NCT07150611)
- Where
- Italy
- Volunteers
- 24 people
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Brain Death, Apnea
Apnea Tests as the Methods of Brain Death Diagnosis.
Apnea test (AT) is the most important clinical test performed usually at the end of brain death (BD) diagnosis procedure. Traditional insufflation apnea test (I-AT) cannot be completed in patients with extremely compromised lung…
- Conditions
- Brain Death, Apnea, Pupillary Anomaly
- Trial name
- DiagBD (NCT03281993)
- Testing
- CPAP AT
- Volunteers
- 76 people
- Sponsor
- Pomeranian Medical University Szczecin
Sleep Apnea, Obstructive, Hypoxia
"Reversibility of Cardiovascular Injury With CPAP Use: Mechanisms Involved"
The purpose of this study is to determine the factors that are associated with improved cardiovascular function with the use of CPAP therapy on subjects diagnosed with moderate to severe obstructive sleep apnea.
- Conditions
- Sleep Apnea, Obstructive, Hypoxia, Hypercapnia, Sleep Disorders
- Trial name
- NCT01317329
- Testing
- Clinically prescribed CPAP therapy
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- University of Wisconsin, Madison
Heart Failure
CPAP Versus Bi-level in Chronic Heart Failure
Introduction: Dyspnea and fatigue are the main clinical symptoms of heart failure and primarily responsible for exercise intolerance found in this syndrome.
- Trial name
- CHF (NCT03287141)
- Testing
- Shuttle walk test, Noninvasive ventilation (Bi-pap), Noninvasive ventilation (CPAP)
- Volunteers
- 18 people
- Sponsor
- Patri-cia Angelica de Miranda Silva Nogueira