Clinical trials: CPAP
Sleep Apnea, Sleep Disordered Breathing
Multinight CPAP for Sleep Apnea Patients
Obstructive sleep apnea (OSA) is a prevalent disorders characterized by intermittent obstructions of the upper airway during sleep.
- Trial name
- NCT02635100
- Testing
- CPAP machine with MNT algorithm
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Obstructive Sleep Apnea (OSA)
Post-extubation Boussignac CPAP System in Adults With Moderate to Severe Obstructive Sleep Apnea
The purpose of this study is to assess the efficacy of the Boussignac positive airway pressure system (a mask) applied immediately following post-operative extubation in improving lung function in patients with obstructive sleep…
- Trial name
- NCT01877928
- Testing
- Boussignac CPAP device, standard CPAP
- Where
- Canada
- Volunteers
- 48 people
- Sponsor
- Queen's University
Obstructive Sleep Apnea
Impact of Automated Education and Follow-up Mechanisms on Patient Engagement
The primary and well-known challenge with continuous positive airway pressure (CPAP) is the incomplete adherence of patients to this therapy.
- Trial name
- EmmiUSleep (NCT02279901)
- Testing
- Telemedicine Education, IVR
- Where
- United States
- Volunteers
- 1,873 people
- Sponsor
- Kaiser Permanente
Infant, Newborn, Diseases, Intubation Complication
Noninvasive Positive Pressure Ventilation During Neonatal Nasal Intubation
The goal of this study is to perform a quality control assessment of our local intubation protocol in any newborn infant requiring endotracheal intubation in the delivery room or neonatal intensive care unit at the Department of…
- Trial name
- IntubAID (NCT06139809)
- Testing
- Intubation
- Where
- Switzerland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Hypoxic Respiratory Failure, Ventilators, Mechanical
Two Modes of Mechanical Ventilation for Intensive Care Patients With Low Blood Oxygen Due to Breathing Difficulties
The study examines individuals admitted to the intensive care unit due to breathing difficulties resulting in not getting enough oxygen into their bodies.
- Trial name
- NCT06140056
- Testing
- Airway pressure release ventilation, Volumen controlled mechanical ventilation
- Where
- 2 sites in Denmark
- Volunteers
- 45 people
- Sponsor
- University Hospital Bispebjerg and Frederiksberg
Obstructive Sleep Apnea
Peer-Driven Intervention for Sleep Apnea
Fragmentation of care can lead to poor treatment adherence in patients with chronic medical conditions which can, in turn, lead to adverse health consequences, poor quality of life, and patient dissatisfaction.
- Trial name
- PCORI (NCT02056002)
- Testing
- Usual Care, Peer-Buddy System
- Where
- United States
- Volunteers
- 362 people
- Sponsor
- University of Arizona
Positional Obstructive Sleep Apnea
Economic Evaluation of Treatment Modalities for Position Dependent Obstructive Sleep Apnea
OBJECTIVES: To evaluate the effect and cost-utility of a combination therapy of SPT+MAD compared with continuous positive airway pressure (CPAP) in patients with moderate positional obstructive sleep apnea (POSA).
- Trial name
- NCT02553902
- Testing
- Sleep position trainer, Mandibular advancement device, Continuous positive airway pressure
- Where
- 2 sites in Belgium, Netherlands
- Volunteers
- 200 people
- Sponsor
- Onze Lieve Vrouwe Gasthuis
Sleep Apnea, Dyslipidaemia
Effect of Nasal CPAP on Lipid Profile in Patients With Dyslipidaemia and Sleep Apnea
OBJECTIVES Main objective: To assess if six months of treatment with CPAP, associated with conventional treatment, improves the lipid profile of patients with dyslipidemia and mild-moderate apnea-hypopnea syndrome (OSA).
- Trial name
- NCT02557412
- Testing
- Continuous positive airway pressure, Intensive lifestyle intervention, Conventional treatment
- Where
- Spain
- Sponsor
- Hospital Universitario La Paz
Obstructive Sleep Apnea Syndrome
Systemic Inflammation and Obstructive Sleep Apnea Syndrome: Effect of Atorvastatin
The aim of this clinical trial is to evaluate the effect of Atorvastatin on the endothelial function improvement during the obstructive sleep apnea syndrome (OSAS) after 3 months of treatment, by a double-blind, randomized…
- Trial name
- StatinflaSAS (NCT00669695)
- Testing
- Atorvastatin treatment, CPAP device
- Where
- 4 sites in France, Switzerland
- Volunteers
- 54 people
- Sponsor
- University Hospital, Grenoble
Sleep Apnea, Heart Failure
Cardiac Function After CPAP Therapy in Patients With Chronic Heart Failure and Sleep Apnea. A Multicenter Study
The role of continuous positive airway pressure (CPAP) in cardiac function in patients with CSA and OSA has been studied with varying results.
- Conditions
- Sleep Apnea, Heart Failure, Cardiovascular Diseases
- Trial name
- NCT00404807
- Testing
- CPAP(Continuous Positive Airway Pressure)
- Where
- Spain
- Volunteers
- 245 people
- Sponsor
- Sociedad Española de Neumología y Cirugía Torácica
Sleep Apnea, Obstructive
Effect of CPAP Treatment in Elderly: Randomized Clinical Trial
Rationale: Almost all the information the investigators have about the effect of continuous positive airway pressure (CPAP) in patients with obstructive sleep apnea (OSA) comes from randomized clinical trials including only…
- Trial name
- NCT02069600
- Testing
- Continuous Positive Airway Pressure
- Where
- Spain
- Volunteers
- 224 people
- Sponsor
- Hospital Universitario La Fe
Sleep Apnea, Obstructive
Titration Pressures in Sleep Apnea Patients Using ThermoSmart® Versus Conventional Humidification
Patients who have Obstructive Sleep Apnea (OSA) may have different Continuous Positive Airway Pressure (CPAP)when titrated with different levels of humidification.
- Trial name
- NCT00681083
- Testing
- Heated breathing tube (CPAP with ThermoSmart), Non heated breathing tube (CPAP with conventional humidification)
- Where
- 2 sites in United States
- Volunteers
- 26 people
- Sponsor
- Fisher and Paykel Healthcare
Obstructive Sleep Apnea
Obstructive Sleep Apnea and Comprehensive Remotely-supervised Rehabilitation Program
The purpose of this study is to investigate the feasibility and effect of a 12-week remotely-supervised rehabilitation program in male patients between 25-65 years old with newly diagnosed obstructive sleep apnea with…
- Trial name
- NCT04759456
- Testing
- Remotely-supervised rehabilitation program
- Where
- Czechia
- Volunteers
- 60 people
- Sponsor
- Brno University Hospital
Obstructive Sleep Apnea
Promoting the Use of CPAP Therapy Among OSA Patients
Obstructive sleep apnea (OSA) is the most common sleep breathing disorder in the U.S. Continuous Positive Airway Pressure (CPAP) therapy is the most effective treatment for OSA.
- Trial name
- NCT04372329
- Testing
- CPAP4HealthySleep system
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- Sarah Alismail
COVID-19, Hypoxemic Respiratory Failure
The Effect of Non-invasive Respiratory Support on Outcome and Its Risks in Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-COV-2)-Related Hypoxemic Respiratory Failure
Coronavirus disease (COVID-19) can result in severe hypoxemic respiratory failure that ultimately may require invasive mechanical ventilation in the Intensive Care Unit (ICU).
- Trial name
- NORMO2 (NCT06033560)
- Testing
- High flow nasal oxygen (HFNO, more than 15 L/min)
- Where
- Netherlands
- Volunteers
- 6,000 people
- Sponsor
- Amsterdam UMC, location VUmc
Obstructive Sleep Apnea, Telemedicine
Global Self-management Telematic Support for Patients With Obstructive Sleep Apnea.
This clinical trial compares the usual follow-up to a program of telematic control and self-management in a group of patients with severe obstructive sleep apnea-hypopnea syndrome (OSAHS), few symptoms and treated with continuous…
- Conditions
- Obstructive Sleep Apnea, Telemedicine, Compliance, Patient
- Trial name
- TELESAS (NCT03792880)
- Testing
- Telematic control and self-management program, Habitual follow-up in Healthcare System
- Where
- 2 sites in Spain
- Volunteers
- 60 people
- Sponsor
- Virgen del Puerto Hospital
Premature Lungs, Respiratory Distress Syndrome
Early Caffeine and LISA Compared to Caffeine and CPAP in Preterm Infants
This study is being conducted to determine whether prophylactic administration of surfactant by the Less Invasive Surfactant Administration (LISA) method reduces the need for mechanical ventilation in the first 72 hours of life…
- Conditions
- Premature Lungs, Respiratory Distress Syndrome, Surfactant Deficiency Syndrome Neonatal
- Trial name
- CaLI (NCT04209946)
- Testing
- Less Invasive Surfactant Administration LISA, Continuous Positive Airway Pressure CPAP
- Where
- 3 sites in United States
- Volunteers
- 180 people
- Sponsor
- Sharp HealthCare
Obstructive Sleep Apnea
Orofacial Myofunctional Therapy and Positive Airway Pressure-CPAP Trial for Mild-to-Moderate Obstructive Sleep Apnea
The goal of this clinical trial is to evaluate the isolated and combined effects of orofacial myofunctional therapy (OMT) and continuous positive airway pressure (CPAP) in adults with mild-to-moderate obstructive sleep apnea.
- Trial name
- OMPACT-OSA (NCT07539870)
- Testing
- Orofacial Myofunctional Therapy, Continuous Positive Airway Pressure, Standard of Care Sleep-Hygiene and Lifestyle Counseling
- Volunteers
- 168 people
- Sponsor
- Saint-Joseph University
Down Syndrome, Obstructive Sleep Apnea Syndrome
Obstructive Sleep Apnea and Neurocognitive and Cardiovascular Function in Children With Down Syndrome
Many individuals with Down syndrome (DS) have breathing problems during sleep. This is called obstructive sleep apnea syndrome (OSAS).
- Trial name
- TRIO (NCT01808508)
- Testing
- Continuous positive airway pressure
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Children's Hospital of Philadelphia
Sleep Apnea, Alveolar Hypoventilation
How Differences in Oximeter Performance May Affect Clinical Decision
In clinical practice discrepancies between overnight SpO2 recordings performed by 2 devices used simultaneously are regularly observed. However, this has not been systematically studied or quantified.
- Conditions
- Sleep Apnea, Alveolar Hypoventilation, Nocturnal Hypoxemia
- Trial name
- NCT04474574
- Testing
- Simultaneous recording of nocturnal SpO2
- Where
- Switzerland
- Volunteers
- 50 people
- Sponsor
- University Hospital, Geneva
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