Clinical trials: CPAP
Sleep Apnea, Obstructive, Patient Compliance
Tailored Intervention to Promote Positive Airway Pressure Adherence
The purpose of this study is to examine the feasibility of a tailored (i.e., individualized) intervention to promote adherence to continuous positive airway pressure therapy (CPAP) in adults with newly-diagnosed, CPAP treated…
- Trial name
- SCIP-PA (NCT01454830)
- Testing
- Tailored, Usual care
- Where
- United States
- Volunteers
- 118 people
- Sponsor
- Milton S. Hershey Medical Center
Obstructive Sleep Apnea, Obesity
Apnea, Bariatric Surgery Versus Continuous Positive Airway Pressure (CPAP) Trial
The purpose of this study is to assess the feasibility of conducting a comparative effectiveness study comparing a medical versus surgical approach to the initial management of obstructive sleep apnea (OSA) in the setting of…
- Trial name
- ABC (NCT01187771)
- Testing
- Laparoscopic Gastric Banding, Continuous Positive Airway Pressure
- Where
- 2 sites in United States
- Volunteers
- 53 people
- Sponsor
- University of Pittsburgh
Obstructive Sleep Apnea
Evaluation of an Incentive-based Intervention to Improve 90-day Adherence in PAP-Naive Patients
This is a prospective, randomized, open-label study to evaluate effectiveness of applying financial and social incentives via a smartphone-based app in helping participants achieve adherence to PAP therapy.
- Trial name
- Project Dahlia (NCT03851094)
- Testing
- Wellth app
- Where
- United States
- Volunteers
- 166 people
- Sponsor
- ResMed
Cystic Fibrosis
Non Invasive Ventilation as Airway Clearance in Patients With Cystic Fibrosis
With the use of Non invasive ventilation the patients with cystic fibrosis will have better lung function (FEV1).
- Trial name
- NCT02083263
- Testing
- Bilevel, PEP mask
- Where
- Sweden
- Volunteers
- 32 people
- Sponsor
- Karolinska University Hospital
Lung Diseases, Sleep Apnea Syndromes
Apnea Positive Pressure Long-Term Efficacy Study
The purpose of this study is to determine the effectiveness of nasal continuous positive airway pressure (CPAP) therapy for the treatment of obstructive sleep apnea syndrome (OSAS).
- Conditions
- Lung Diseases, Sleep Apnea Syndromes, Sleep
- Trial name
- APPLES (NCT00051363)
- Testing
- Active CPAP
- Where
- 5 sites in United States
- Volunteers
- 1,105 people
- Sponsor
- Stanford University
Acute Respiratory Failure
Pilot Study on Pairing Sedation Strategies and Weaning
A three-arm, randomized, pilot study, to assess the feasibility for the analgesia-first sedation (AFS) study arm/intervention (Fentanyl push first).
- Trial name
- NCT02219659
- Testing
- Sedation Protocol with Daily Interruption, Sedation Protocol Without Daily Interruption, Fentanyl Push First
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- MemorialCare Health System
Obstructive Sleep Apnea Syndrome, Restless Leg Syndrome
Prevalence of OSAS in Chinese Elderly and Its CPAP Compliance
Objective: Obstructive sleep apnoea syndrome (OSAS) is a common form of sleep-disordered breathing (SDB) causing sleep fragmentation, daytime sleepiness, cognitive function impairment, and poor health status in addition to…
- Trial name
- NCT02085720
- Testing
- CPAP therapy
- Where
- Hong Kong
- Volunteers
- 819 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Obstructive Sleep Apnea
Metabolic Impact of Intermittent CPAP
Obstructive sleep apnea is a risk factor for diabetes and cardiovascular disease, by unknown mechanisms. The investigators hypothesize that sleep apnea changes glucose and lipid metabolism during sleep, which over time could lead…
- Trial name
- MIIC (NCT02824263)
- Testing
- CPAP withdrawal
- Where
- United States
- Volunteers
- 144 people
- Sponsor
- Johns Hopkins University
Spinal Cord Injury, Sleep Apnea, Obstructive
Sleep-Disordered Breathing in Chronic SCI
The purpose of this study is to examine impact of Sleep Disordered Breathing (SDB) treatment in persons with chronic Spinal Cord Injury (SCI).
- Trial name
- NCT02176928
- Testing
- AutoPAP
- Where
- 4 sites in United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Miami
Sleep Apnea, Obstructive
COMMunication and Education for the New CPAP Experience
The purpose of this research study is to examine the effect of a couple-oriented education and support intervention on patient- and partner -reported outcomes (positive airway pressure (PAP) adherence) in patients newly diagnosed…
- Trial name
- COMMENCE (NCT01377584)
- Testing
- Couple-oriented intervention, Patient-oriented intervention, Continuous positive airway pressure (CPAP)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Pittsburgh
Obstructive Sleep Apnea
CPAP vs AutoCPAP for Treatment of Obstructive Sleep Apnea (OSA) in the Postoperative Setting
The purpose of this study is to determine if an Autoadjusting CPAP machine is better than the regular CPAP machine in treatment of Obstructive Sleep Apnea in the postoperative setting.
- Trial name
- NCT00588848
- Testing
- Autoadjusting CPAP (VPAP Auto), CPAP
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- MetroHealth Medical Center
Sleep Apnea, Obstructive
Telecommunications System in Sleep Apnea
This study is investigating the effects of a telecommunications system designed to improve patient adherence with prescribed positive airway pressure (CPAP).
- Trial name
- NCT00232544
- Testing
- Telecommunications system, TLC-Control
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- VA Office of Research and Development
Obstructive Sleep Apnea
Mechanisms of Upper Airway Obstruction
The current study is designed to examine underlying mechanisms of action of lingual muscles in the maintenance of airway patency during sleep.
- Trial name
- DISE-CAD (NCT04322097)
- Testing
- Hypoglossal Nerve Stimulation
- Where
- United States
- Volunteers
- 133 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Xerostomia
NeutraSal Treatment for Xerostomia in OSAS Patients Using CPAP Therapy
To assess whether the daily use of NeutraSal will prevent or reduce dry mouth in patients undergoing CPAP therapy for OSAS and improve CPAP compliance
- Trial name
- NCT02107300
- Testing
- NeutraSal
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Medical University of South Carolina
Obstructive Sleep Apnea
Cost Effectiveness of Ambulatory Management for Veterans With Sleep Apnea
This research study is comparing home and in-laboratory testing of veterans with suspected obstructive sleep apnea, a common breathing disorder during sleep.
- Trial name
- VSATT (NCT00880165)
- Testing
- Continuous positive airway pressure apparatus
- Where
- 2 sites in United States
- Volunteers
- 296 people
- Sponsor
- US Department of Veterans Affairs
Obstructive Sleep Apnea (OSA)
Differences in Efficacy Between Nasal and Oronasal Masks in the Treatment of OSA With CPAP
Our group previously conducted a study looking at the performance of three styles of positive airway pressure masks during laboratory treatment studies for obstructive sleep apnea, and we found that patients using a full-mask…
- Trial name
- NCT01909674
- Testing
- Switch CPAP mask type
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Sleep Disordered Breathing
Continuous Positive Airway Pressure and Cardiometabolic Risk
The hypothesis for this study is that children with sleep disordered breathing will benefit from treatment with Continuous Positive Airway Pressure (CPAP) or Bi-level Positive Airway Pressure (BiPAP) in terms of reduction in…
- Trial name
- NCT01403194
- Testing
- CPAP/BiPAP
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Mayo Clinic
Human Immunodeficiency Virus, Obstructive Sleep Apnea
Obstructive Sleep Apnea Endotypes and Impact on Phenotypes of People Living With HIV
The investigators seek to understand how the different underlying causes of OSA affect the way people living with HIV (PLWH) experience OSA.
- Trial name
- PLWH/OSA (NCT03575143)
- Where
- United States
- Volunteers
- 132 people
- Sponsor
- University of California, San Diego
Sleep Apnea, Sleep Disordered Breathing
Sleepiness and the Effects of CPAP on Salivary Cortisol and Alpha-Amylase Levels in Patients With Sleep Apnea
Patients with Obstructive Sleep Apnea Syndrome (OSAS) will evidence higher levels of salivary cortisol and alpha-amylase levels prior to use of placebo and continuous positive airway pressure (CPAP) and will evidence a decrease…
- Trial name
- NCT01196117
- Testing
- 14 days of CPAP therapy
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Medical College of Wisconsin
Acute Cardiogenic Pulmonary Edema
Non Invasive Mechanical Ventilation in Acute Cardiogenic Pulmonary Edema
Cardiogenic pulmonary edema (CPE) is a common medical emergency and noninvasive ventilation (NIV) in addition to conventional medical treatment might be beneficial for patients with CPE.
- Trial name
- NCT00912158
- Testing
- standard therapy (ST), CPAP, BIPAP
- Where
- Egypt
- Volunteers
- 129 people
- Sponsor
- Assiut University