Clinical trials: Caffeine
Preterm, Apnea of Prematurity
Caffeine Citrate Use and Electronic Activity of the Diaphragm (EDI) Changes
Caffeine citrate, the first-line agent for apnea of prematurity, enhances diaphragmatic activity. EDI values of neurally adjusted ventilatory assist (NAVA) modes can be used to quantify the diaphragmatic activity triggered by…
- Conditions
- Preterm, Apnea of Prematurity, Caffeine
- Trial name
- NCT05393817
- Testing
- caffeine citrate
- Where
- South Korea
- Volunteers
- 14 people
- Sponsor
- Seoul St. Mary's Hospital
Muscle Damage
Effect of Strength Versus Endurance Training on Muscle Damage in Gym Athletes on Caffeine Supplementation.
Dietary supplements to enhance exercise and athletic performance come in a variety of forms, including tablets, capsules, liquids, powders, and bars.
- Trial name
- NCT06086691
- Testing
- Strength Training with Caffeine, Endurance Training with Caffeine
- Where
- Pakistan
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Analgesia
Management of Post Dural Pucture Headache After Lower Limb Surgeries: Oral Prednisolone vs Oral Pregabalin
The aim of this study is to compare between oral prednisolone and oral pregabalin in management of PDPH to detect effectiveness of the treatment in reducing severity of PDPH, total rescue analgesic consumption and adverse effects…
- Trial name
- NCT04662125
- Testing
- caffeine, paracetamol tablet, Oral prednisolone, oral pregabalin
- Where
- Egypt
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Healthy Volunteers
A Study to Assess the Effect of BMS-986419 on the Single Dose Drug Levels of Probe Substrates in Healthy Participants
The purpose of this study is to assess the effect of BMS-986419 on the pharmacokinetics (PK) of single doses of caffeine (CYP1A2 substrate), bupropion (CYP2B6 substrate), midazolam (CYP3A4 substrate), flurbiprofen (CYP2C9…
- Trial name
- NCT05932277
- Testing
- BMS-986419, Caffeine, Bupropion
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Bristol-Myers Squibb
Pharmacological Action of Drug
the Incidence of Necrotizing Enterocolitis in Preterm With Respiratory Distress Syndrome Undergoing Caffeine Therapy
It is a randomized, prospective study; it will be carried out in the NICU at Alzahraa University Hospital including 50 newborn babies diagnosed with respiratory distress syndrome. The purpose of this study is to : 1.
- Trial name
- NCT06097767
- Testing
- Caffeine citrate, Amikacin
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Al-Azhar University
Apnea of Prematurity, Caffeine
Target Weaning Oxygen to Determine Cafffeine Duration for AOP
Caffeine, a typical representative of methylxanthine, is world-widely used to manage apnea of prematurity (AOP) in neonatology. However, an appropriate medication regimen of caffeine has not been well defined until now.
- Conditions
- Apnea of Prematurity, Caffeine, Weaning Oxygen, Medicine Regimen
- Trial name
- DCAP (NCT04868565)
- Testing
- Caffeine Citrate 20 MG/1 ML Intravenous Solution [CAFCIT]
- Where
- 41 sites in China
- Volunteers
- 310 people
- Sponsor
- Children's Hospital of Chongqing Medical University
Caffeine
Caffeinated Gum Softball Performance
The purpose of this study was to investigate the effects of caffeinated chewing gum on female softball pitching and hitting performance.
- Trial name
- NCT06079996
- Testing
- CAFFEINE GUM
- Where
- Taiwan
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Chih-Hui Chiu
Sport Performance
Pre-workout Supplementation and Basketball
Pre-workout supplements (PWS) consumption in recreationally or physically trained males lead to many performance-enhancing benefits, including improvements in mean power output during single and repeated sprints, agility…
- Trial name
- NCT06059911
- Testing
- Multi-ingredient dietary supplement (caffeine, creatine monohydrate, β-alanine, citrulline malate, BCAA)
- Where
- Greece
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Athanasios Z. Jamurtas
Healthy Volunteers
A Study to Evaluate the Drug-drug Interaction Potential of BMS-986196 in Healthy Participants
This study is designed to assess the effect of BMS-986196 on the drug levels of caffeine, montelukast, flurbiprofen, omeprazole, midazolam, digoxin, and pravastatin in healthy participants.
- Trial name
- NCT05852769
- Testing
- BMS-986196, Caffeine, Montelukast
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Bristol-Myers Squibb
Second Stage of Labor
Caffeine in the Second Stage of Labor in Low-risk Nulliparous Mothers at Term
Single blind, randomized control trial to determine benefit of caffeine and sodium benzoate on the second stage of labor
- Trial name
- NCT05906303
- Testing
- Caffeine and Sodium Benzoate Injection, Normal Saline
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- The Reading Hospital and Medical Center
Caffeine
Effects Of Caffeine On Cognitive Performance
Caffeine is a potent central nervous system stimulant that increases the activity in the prefrontal cortex and can improve cognitive skills.
- Trial name
- NCT05995314
- Testing
- 3 mg/kg of caffeine, 6 mg/kg of caffeine
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Castilla-La Mancha
Intermittent Hypoxia
Intermittent Hypoxia and Caffeine in Infants Born Preterm
Intermittent Hypoxia and Caffeine in Infants Born Preterm (ICAF) Our proposal will address the critical question: is persisting intermittent hypoxia (IH) in preterm infants associated with biochemical, structural, or functional…
- Trial name
- ICAF (NCT03321734)
- Testing
- Caffeine
- Where
- 15 sites in United States
- Volunteers
- 170 people
- Sponsor
- Children's National Research Institute
Healthy
A Study in Healthy People to Test Whether BI 730357 Influences the Amount of Caffeine, Warfarin, Omeprazole, and Midazolam in the Blood
The trial will be performed to assess the influence of BI 730357 on the pharmacokinetics of caffeine, warfarin, omeprazole and midazolam.
- Trial name
- NCT04679948
- Testing
- Percoffedrinol®, Coumadin®, Antra MUPS®
- Where
- Germany
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Recurrent Ovarian Cancer
A Drug-drug Interaction Study Of Fluzoparib (SHR3162) on Patients With Recurrent Ovarian Cancer
Primary objective: To evaluate the pharmacokinetic effects of fluzoparib on caffeine, S-warfarin, omeprazole, midazolam, repaglinide and bupropion in patients with recurrent ovarian cancer.
- Trial name
- NCT04718740
- Testing
- fluzoparib
- Where
- China
- Volunteers
- 33 people
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
Genetic Predisposition, Caffeine
Genetics in the Effect of Caffeine on Fat Oxidation
Genetic polymorphism on the effect of oral caffeine intake on fat oxidation during exercise has been studied in active and healthy population performing an incremental test on a cycle ergometer with 3-min stages at workloads from…
- Conditions
- Genetic Predisposition, Caffeine, Fat Burn
- Trial name
- NCT05975489
- Testing
- Acute caffeine supplementation
- Where
- Spain
- Volunteers
- 32 people
- Sponsor
- Universidad Francisco de Vitoria
Sportive Performance, Caffeine
Effects of Caffeine on Upper Extremity Performance
It was aimed to apply caffeine supplement to elite basketball players and to investigate the effects of this supplement on upper extremity performance, lactic acid level and fatigue.
- Trial name
- NCT05916352
- Testing
- Caffeine Supplement
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cyprus International University
Healthy Adults
Ketone Production With Acute Caffeine Intake
Evaluate the effect of a caffeine supplement on the stimulation of lipolysis and the production of ketones in healthy adults (N=10).
- Trial name
- NCT02694601
- Testing
- Control, Caffeine low dose, Caffeine high dose
- Where
- Canada
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Université de Sherbrooke
Female Sexual Arousal Disorder
Examining Caffeine as a Treatment for Antidepressant-induced Arousal Dysfunction in Women
Antidepressants have negative effects on genital arousal function that hinder quality of life and jeopardize medication adherence.
- Trial name
- NCT05685407
- Testing
- Caffeine
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Texas at Austin
Carbohydrate, Caffeine
Carbohydrate Rinsing and Caffeine Gum on Performance of Romanian Deadlifts Performance
Two experiments were completed to investigate the effects of carbohydrate mouth rinsing and caffeine gum chewing on inertial resistance exercise performance.
- Trial name
- NCT05900349
- Testing
- Carbohydrate mouth rinsing, 200 mg caffeine gum
- Where
- Taiwan
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- National Taiwan Sport University
Neoplasms
Pharmacokinetic Drug-Drug Interaction Study of Rucaparib
The purpose of this study is to assess pharmacokinetic concentrations of multiple probes alone followed by assessment of the same drug pharmacokinetic concentrations when the patient has steady-state exposure to rucaparib…
- Trial name
- DDI (NCT02740712)
- Testing
- Caffeine, Warfarin, Omeprazole
- Where
- 3 sites in Poland
- Volunteers
- 17 people
- Sponsor
- pharmaand GmbH