Clinical trials: Caffeine
Autism Spectrum Disorder
Autism ALERT Expansion
Autism Access Link for Early Referral and Treatment [ALERT], the intervention proposed in this application, is a novel state-wide referral and case management platform that PCPs can activate to ensure that a child with suspected…
- Trial name
- NCT06246890
- Testing
- Autism ALERT
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Oregon Health and Science University
Premature Atrial Contractions, Premature Ventricular Contractions
Coffee and Real-time Atrial and Ventricular Ectopy
Atrial fibrillation (AF) and heart failure (HF) are morbid, costly, and incompletely understood diseases that have reached epidemic proportions worldwide.
- Trial name
- CRAVE (NCT03671759)
- Testing
- Start: On Caffeine, Start: Off Caffeine
- Where
- United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Emergency Room Utilization
Oscar Health Patient Pings
Oscar spends a significant amount of money every year on high cost high need individuals. With this increase in health care spending, Oscar Health is looking to expand care post emergency room and inpatient utilization for their…
- Trial name
- NCT02923024
- Testing
- Patient Ping
- Sponsor
- University of Pennsylvania
Depression, Anxiety
A Mindfulness-Based Stress Reduction Training Program Model
Mindfulness-based practices are used to regulate mood, alleviate or completely eliminate symptoms that cause stress and depression, and positively influence well-being.
- Conditions
- Depression, Anxiety, Stress, Well-Being, Psychological
- Trial name
- NCT07544355
- Testing
- The mindfulness group-"Mindfulness-Based Stress Reduction Program", The life skills workshop group-"Lifestyle Management and Well-being Workshop"
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Istanbul Medeniyet University
Analgesia
Management of Post Dural Pucture Headache After Lower Limb Surgeries: Oral Prednisolone vs Oral Pregabalin
The aim of this study is to compare between oral prednisolone and oral pregabalin in management of PDPH to detect effectiveness of the treatment in reducing severity of PDPH, total rescue analgesic consumption and adverse effects…
- Trial name
- NCT04662125
- Testing
- caffeine, paracetamol tablet, Oral prednisolone, oral pregabalin
- Where
- Egypt
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Caffeine, Thermoregulation
The Effects of Caffeine on Exercise Physiology and Time-trial Performance in a Hot Environment
Maintaining a stable core temperature is vital for physiological function; yet, exercise in heat can be problematic, and there is risk of exertional heat-related illness (Flouris \& Schlader, 2015; Leyk et al., 2019; Périard et…
- Trial name
- NCT07129200
- Testing
- Hot environment, Thermoneutral environment
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- St. Mary's University, Twickenham
Pain, Acute
Mind-body Therapies for Injury-related Pain Management in Elite Athletes
This study will utilize a replicated single case experimental design (RSCD) to investigate the effectiveness of a brief mindfulness meditation (MM) vs clinical hypnosis (HYP) training for improving pain in injured elite athletes.
- Trial name
- NCT06095687
- Testing
- Mindfulness Meditation, Clinical Hypnosis
- Where
- Australia
- Sponsor
- The University of Queensland
Irritable Bowel Syndrome
Effect of Autogenic Relaxation Training on Irritable Bowel Syndrome In Adult Females
This study will be conducted to determine the effect of autogenic relaxation training on irritable bowel syndrome in adult females.
- Trial name
- NCT07533500
- Testing
- Autogenic relaxation training, Aerobic exercises, Lifestyle modification
- Where
- Egypt
- Volunteers
- 44 people
- Sponsor
- Cairo University
Gestational Diabetes, Hypertension in Pregnancy
Sleep Improvement Therapy Affects Pregnancy Outcomes in Chinese Singletons and Twins by Improving Sleep Quality
During pregnancy, the physical and psychological changes of pregnant women, hyperemesis gravidarum, uterine compression, frequent urination, hip or pelvic pain, back pain, leg cramps, gastroesophageal reflux, changes in mental…
- Conditions
- Gestational Diabetes, Hypertension in Pregnancy, Preterm Labor, NICU Infants
- Trial name
- NCT06687044
- Testing
- Sleep restriction, Stimulation control, Cognitive therapy
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Jun Wei
Urinary Dysfunction
Effects of Pelvic Floor Muscle Training Combined With Bladder Training on Some Parametrs of Men With Urinary Frequency
This prospective, single-center, parallel-group, assessor-blinded randomized controlled trial will include 120 voluntary male participants who have had complaints of urinary frequency for at least 3 months and meet the inclusion…
- Trial name
- NCT07719400
- Testing
- Bladder training plus pelvic floor muscle training, Bladder Training
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Bingol University
Hypoxic-Ischemic Encephalopathy
Caffeine for Hypoxic-Ischemic Encephalopathy
Hypoxic-ischemic encephalopathy (HIE) due to perinatal asphyxia is common and often fatal. Therapeutic hypothermia reduces mortality and morbidity in infants with HIE.
- Trial name
- NCT03913221
- Testing
- Caffeine Citrate 5 mg/kg, Caffeine Citrate 10 mg/kg
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- University of North Carolina, Chapel Hill
Healthy
A Study of LY4515100 in Healthy Participants
The main purpose of this study is to assess the safety and tolerability of LY4515100 when given orally to healthy participants. LY4515100 will be given by itself or with other medicines.
- Trial name
- NCT07339722
- Testing
- LY4515100 via SAD, LY4515100 via MAD, LY4515100
- Where
- United States
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
Caffeine
Does Caffeine Facilitate Human Reward Learning Behaviors?
"Learning from the rewards" is underlying the formulation of knowledge and habits in daily life. Caffeine is the most commonly used "psychoactive" substance that could change one's mind state by affecting the brain and nervous…
- Trial name
- ADoRe (NCT05325502)
- Testing
- caffeine, mannitol
- Where
- Switzerland
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Yu-Shiuan Lin
Normal Controls
Herbal Extract Study
The objective of this study is to assess the effects of an herbal extract on mental energy in healthy human subjects.
- Trial name
- NCT02095301
- Testing
- Herbal Beverage
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- PepsiCo Global R&D
COPD (Chronic Obstructive Pulmonary Disease), COPD Exacerbations
The REVIVE Pivotal Study
The goal of this study is to test whether a new treatment called the Ryme Medical Targeted Lung Denervation (TLD) Catheter is safe and effective for people with moderate to severe chronic obstructive pulmonary disease (COPD).
- Conditions
- COPD (Chronic Obstructive Pulmonary Disease), COPD Exacerbations, COPD Patients, COPD Acute Exacerbation
- Trial name
- REVIVE (NCT07361653)
- Testing
- Ryme TLD
- Volunteers
- 300 people
- Sponsor
- Ryme Medical, Inc.
Syncope, Vasovagal
The Effect of CPC on Aborting Tilt Induced Syncope in Patients With a History of Vasovagal Syncope or Near Syncope
Syncope is defined as transient loss of consciousness associated with inability to maintain postural tone with rapid and spontaneous recovery.
- Trial name
- NCT04972123
- Testing
- CPC - Capsaicin, Phenylephrine, Caffeine, Tilt Table Test
- Where
- United States
- Volunteers
- 143 people
- Sponsor
- University of Wisconsin, Madison
Absorption, Pharmacokinetic
Clinical Study to Compare the Effect of an Oral Rehydration Solution on the Rate of Absorption of Functional Ingredients
The objective of this study was to compare the individual pharmacokinetics of functional ingredients included in an oral rehydration solution (ORS) with or without the inclusion of active base ingredients (carbohydrate and…
- Trial name
- NCT06524674
- Testing
- Hydration Multiplier + Energy, Hydration Multiplier + Sleep, Energy Comp
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Liquid I.V.
Smoking
Effects of a Specific Substance in Smokers
Although rates of cigarette use are declining, the proportion of nondaily smokers is rising, particularly among young adults. Among young adults, nondaily smoking is associated with negative health consequences and, for some, may…
- Trial name
- NCT04281979
- Testing
- Study Agent
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Enuresis, Nocturnal
The Behavioral Therapy for Primary Monosymptomatic Nocturnal Enuresis
A prospective randomized clinical study was conducted at Urology departments, faculties of medicine, Fayoum and Cairo Universities.
- Trial name
- NCT07015320
- Testing
- urotherapy, no intervention
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Cairo University
Premature Infant Disease, Apnea of Prematurity
Caffeine Citrate in Preterm Infants at Risk of Apnea in Zambia
The goal of this clinical trial is to learn if caffeine citrate prevents apneic events that result in sick visits in moderately preterm infants after discharge from the hospital.
- Conditions
- Premature Infant Disease, Apnea of Prematurity, Development, Infant
- Trial name
- NCT06518603
- Testing
- Caffeine citrate 20mg/kg/day
- Where
- Zambia
- Volunteers
- 340 people
- Sponsor
- University of Alabama at Birmingham
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