Clinical trials: Caffeine, completed
Drug Drug Interaction (DDI)
Drug-Drug Interaction (DDI) Study for TD-9855
This study is designed to assess the effect of fluvoxamine, itraconazole and smoking on the PK disposition of multiple doses TD-9855 in healthy male subjects.
- Trial name
- NCT03432793
- Testing
- TD-9855, Fluvoxamine, Itraconazole
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Theravance Biopharma
Depression, Depressive Disorder, Major
Sleep, Wake and Light Therapy for Depression
The aim of this study is to determine if altering the pattern of one's sleep and having light therapy can speed up the treatment of depression.
- Conditions
- Depression, Depressive Disorder, Major, Depression, Unipolar, Depression Moderate
- Trial name
- NCT03405493
- Testing
- Wake and Light Therapy, Sleep and Light Therapy
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- King's College London
Healthy
Pre-workout Supplement Versus Caffeine on Energy Expenditure.
The primary purpose of this study was to examine the acute effects of a multi-ingredient pre-workout supplement versus an ergogenic dose of caffeine (6 mg/kg) on energy expenditure during low-intensity exercise.
- Trial name
- NCT04539054
- Testing
- ENGN Shred, Nutricost caffeine powder, Crystal Light
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Northern Illinois University
Dietary Modification
Effects of a Pre-Workout Dietary Supplement on Training Adaptations
The purpose of this study is to examine the effects of a pre-workout dietary supplement during resistance training on training adaptations.
- Trial name
- NB2 (NCT02999581)
- Testing
- C4 Extreme, C4 Extreme (without Advantra Z)
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Texas A&M University
Healthy
The Effect of BI 187004 on the Pharmacokinetics of Cytochrome P450 Substrates (Caffeine, Warfarin, Omeprazole, Metoprolol and Midazolam) and a P Glycoprotein Substrate (Digoxin)
To assess the influence of BI 187004 on kinetics of cytochrome P450 (CYP) and P glycoprotein (P-gp) probe drugs as a means of predicting drug-drug interactions.
- Trial name
- NCT02254148
- Testing
- midazolam, caffeine, digoxin
- Where
- Germany
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Schizophrenia, Caffeine
The Impact of Caffeine on Cognition in Schizophrenia
Caffeine is the most used psychoactive drug in Canada, with regular consumption by 88% of the adult population, While rates of caffeine consumption are considered to be high in the general population, there is some evidence that…
- Trial name
- NCT02832401
- Testing
- Caffeine
- Where
- Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Nova Scotia Health Authority
Overweight
Effects of Caffeinated and Decaffeinated Coffee on Body Weight and Glucose Tolerance
Habitual consumption of coffee may have substantial beneficial effects on glucose metabolism according to recent findings of epidemiological studies in the U.S., Europe, and Japan.
- Trial name
- NCT00305097
- Testing
- Decaffeinated coffee, Caffeinated coffee, No coffee
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Cognitive Change, Sleep Deprivation
Sleep Deprivation Study
The purpose of this study is to evaluate the measures of brain function, both neurophysiological (event-related potentials (ERPs) and functional (cognitive assessments), in response to sleep deprivation.
- Conditions
- Cognitive Change, Sleep Deprivation, Caffeine
- Trial name
- NCT05560620
- Testing
- Sleep Deprivation, Caffeine, No Caffeine
- Where
- Canada
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- NeuroCatch Inc.
Healthy Volunteers
A Study to Evaluate the Drug-drug Interaction Potential of BMS-986196 in Healthy Participants
This study is designed to assess the effect of BMS-986196 on the drug levels of caffeine, montelukast, flurbiprofen, omeprazole, midazolam, digoxin, and pravastatin in healthy participants.
- Trial name
- NCT05852769
- Testing
- BMS-986196, Caffeine, Montelukast
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Bristol-Myers Squibb
Dysmenorrhea, Spinal Stabilization
The Effect of Spinal Stabilization Training in Women With Dysmenorrhea
The study, designed as a randomized controlled experimental trial, was conducted at Tonya Vocational School. Institutional approval was obtained to carry out the study at Tonya Vocational School (Appendix-).
- Conditions
- Dysmenorrhea, Spinal Stabilization, Menstrual Symptoms, Exercise Training
- Trial name
- NCT07563426
- Testing
- Spinal stabilization exercise group, Relaxation exercise group
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Sevtap Günay
Postoperative Ileus
Coffee Consumption for Intestinal Function Recovery After Laparoscopic Gynecologic Surgery
Minimally invasive surgery (MIS) has revolutionized women's healthcare. Laparoscopy is an excellent route of MIS. Today, laparoscopic surgery is one of the major procedure in the management of a gynecologic disease.
- Trial name
- NCT03963180
- Testing
- coffee
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Erzincan Military Hospital
Premenstrual Syndrome, Pilates Exercise
Clinical Pilates' Impact on Fitness, Symptoms & Kinesiophobia in PMS
Premenstrual syndrome (PMS) is characterized by a series of somatic and psychological symptoms of varying severity that occur during the luteal phase of the menstrual cycle, affecting approximately 30% of women and resolving with…
- Trial name
- NCT06835062
- Testing
- Recommendations for Enhancing General Well-Being, Clinical Pilates
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Atlas University
Obesity
Appetite Suppression Effects of an Herbal Combination of Yerba maté, Guarana, Damiana (YGD), and 12 Other Herbal Components, Versus YGD Supplementation Alone
Background: Supplementation with the combination of Yerba maté, guarana and damiana (YGD) has been found to slow gastric emptying by 15 to 58%, and to induce a substantial weight loss over 45 days without changes in diet.
- Trial name
- YGD (NCT02185638)
- Testing
- Appetite suppressant properties of YGD and A20-50
- Where
- Denmark
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Periorbital Hyperpigmentation, Periorbital Edema
A 12 Week Study to Evaluate the Efficacy of an Eye Cream
This single center, open-label clinical study was conducted to assess the efficacy and tolerance of a topical eye cream when used over the course of 12 weeks by healthy women with moderate to severe under-eye dark circles…
- Conditions
- Periorbital Hyperpigmentation, Periorbital Edema, Fine Lines, Wrinkle
- Trial name
- NCT05807620
- Testing
- Gentle Cleansing Lotion, Facial Moisturizer, Sunscreen SPF 30
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Revision Skincare
Dietary Supplements, Caffeine
Effect of Acute Caffeine and Beetroot Juice Intake on Strength, Power, and Muscular Endurance
Introduction: Several studies have evaluated and confirmed the ergogenic effect of acute caffeine and beetroot juice intake on sports performance.
- Conditions
- Dietary Supplements, Caffeine, Nitrates, Sports Performance
- Trial name
- CAF+BJ (NCT06596395)
- Testing
- Acute caffeine and beetroot juice, Acute caffeine, Acute beetroot juice
- Where
- Spain
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Alcala
Sports Performance, Cognitive Performance During Physical Activity
Multi-Ingredient Supplementation in Professional Football Players
This randomized double-blind placebo-controlled trial will investigate the effects of multi-ingredient supplementation containing taurine, caffeine, and phosphatidylserine on physical performance, cognitive function, cognitive…
- Conditions
- Sports Performance, Cognitive Performance During Physical Activity, Fatigue, Recovery
- Trial name
- TCP-Soccer (NCT07604519)
- Testing
- taurine, Caffeine, Phosphatidylserine
- Where
- 5 sites in Hungary, Poland and 1 more
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Vizja University in Warsaw
Hypertension in Pregnancy
Remote Surveillance of Postpartum Hypertension
Women with hypertensive disorders of pregnancy need postpartum blood pressure (BP) surveillance to detect persistent hypertension. Various barriers result in only 30% attendance at postpartum BP visits.
- Trial name
- TextBP (NCT03185455)
- Testing
- Remote (text based) surveillance
- Where
- United States
- Volunteers
- 206 people
- Sponsor
- University of Pennsylvania
At Home Setting, Coffee With or Without Caffeine
Do It Yourself (DIY) Coffee Study; Test Effect of Coffee on Cognition in an at Home Setting
Subjects will perform experiments in an at home-setting. The effect of caffeine in coffee will be tested in subjects with computer tests on attention and alertness.
- Trial name
- NCT02061982
- Testing
- Coffee consumption
- Where
- Netherlands
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- TNO
Atrial Fibrillation
EHR-Embedded Decision Support to Prevent Stroke in Patients With AF
Background and Significance - Atrial fibrillation (AF) is the most common significant cardiac rhythm disorder and is a powerful common risk factor for stroke.
- Trial name
- NCT04099485
- Testing
- Electronic Health Record Best Practice Advisory
- Where
- United States
- Volunteers
- 608 people
- Sponsor
- University of Cincinnati
Chronic Kidney Disease
Med-alert Bracelet in Chronic Kidney Disease
This is a pilot observational study to evaluate subjects with chronic kidney disease acceptance of an alert device linked to an informational website intended to increase recognition of chronic kidney disease, and to guide…
- Trial name
- NCT00883389
- Testing
- Medical Alert Bracelet
- Volunteers
- 26 people
- Sponsor
- University of Maryland, Baltimore