Clinical trials: Caffeine
Frailty
Autonomy Among Physically Frail Older People in Nursing Homes
The purpose of this study is to assess the status of perceived autonomy and to evaluate the effectiveness of individually tailored programmes on perceived autonomy in physically frail older people living in nursing homes.
- Trial name
- NCT00783055
- Testing
- Individually tailored programmes
- Where
- Denmark
- Volunteers
- 66 people
- Sponsor
- University of Southern Denmark
Supportive Care, Cancer
Feasibility Study of the Advanced Symptom Management System (ASyMS) in Canadian Cancer Patients
The Advanced Symptom Monitoring and Management System - Canada (ASyMS-Can) is a remote phone-based symptom management system that prompts patient self-care and clinician telephone triage and intervention based on alerts for…
- Trial name
- ASyMS-Can (NCT03335189)
- Testing
- ASyMS-Can
- Where
- Canada
- Volunteers
- 84 people
- Sponsor
- University Health Network, Toronto
Oral Hygiene, Oral Health
Oral Hygiene Among Portuguese Older Adults
The goal of this clinical trial was to compare two different oral hygiene instruction methods on oral hygiene behavior in older adults.
- Conditions
- Oral Hygiene, Oral Health, Older
- Trial name
- NCT06444490
- Testing
- General Approach Instruction, Personalised Technique Instruction
- Where
- Portugal
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Egas Moniz - Cooperativa de Ensino Superior, CRL
Chronic Insomnia
Effects of Tai Chi on Chronic Insomnia Disorder Combined With Hyperarousal/Anxiety
This study focuses on individuals with chronic insomnia combined with excessive arousal/anxiety, with the main objective of investigating the effectiveness of Tai Chi in treating CI with excessive arousal/anxiety.
- Trial name
- NCT06967974
- Testing
- Tai Chi + Sleep Hygiene Education, Sleep Hygiene Education
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Xuanwu Hospital, Beijing
Acute Myeloid Leukemia
A Study to Describe the Safety and Effectiveness of Venetoclax in Acute Myeloid Leukemia (AML) Patients (REVIVE Study)
This study will describe the safety and effectiveness of venetoclax in AML patients in routine clinical practice in Israel. The decision to treat with venetoclax is made by the physician prior to any decision regarding…
- Trial name
- REVIVE (NCT03987958)
- Where
- 12 sites in Israel
- Volunteers
- 100 people
- Sponsor
- AbbVie
Overweight, Obese
The Impact of Integrating an Internet Weight Control Program Into Primary Care
The investigators will conduct a randomized controlled trial comparing the effects of three interventions on weight loss at 12 months.
- Trial name
- NCT01606813
- Testing
- Usual Care, Brief Physician Counseling, Referral and access to an internet weight control program
- Where
- United States
- Volunteers
- 611 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Endotoxemia
A Possible Therapeutic Role for Adenosine During Inflammation
The adenosine receptor is known for its anti-inflammatory actions and could therefore be a potential target in the treatment of sepsis and septic shock.
- Trial name
- NCT00513110
- Testing
- AMPD1 polymorphism, Caffeine infusion
- Where
- Netherlands
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
RSV Infection, Drug Drug Interaction
A Study to Evaluate the Drug-Drug Interaction of EDP-323 With Midazolam, Caffeine, and Rosuvastatin in Healthy Participants
The primary aim of this study is to assess the effect of EDP-323 on the pharmacokinetics and safety of midazolam, caffeine, and rosuvastatin in healthy adult participants.
- Trial name
- NCT06917508
- Testing
- EDP-323, Midazolam, Caffeine
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Enanta Pharmaceuticals, Inc
Atherosclerosis, Coronary Artery Disease
Feasibility of a Multifaceted Program to Reduce Cardiovascular Complications of Air Pollution
The main goal of this clinical trial is to evaluate the feasibility of conducting a large-scale clinical trial testing a program containing several aspects for reducing the effects of air pollution on cardiovascular health (which…
- Conditions
- Atherosclerosis, Coronary Artery Disease, Peripheral Arterial Disease, Ischemic Stroke
- Trial name
- NCT06261606
- Testing
- Hybrid strategy
- Where
- Iran
- Volunteers
- 50 people
- Sponsor
- Parham Sadeghipour
Bipolar Disorder (BD)
Project MOVE Bipolar
The investigators propose a randomized clinical trial in which 24 individuals with bipolar disorder are assigned to one of three arms, with each successive arm having an added component that may serve to increase and maintain…
- Trial name
- NCT07767032
- Testing
- BA, SHE, HE
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Butler Hospital
Drug Mechanism, Metabolism Medication Toxicity
Pharmacology Space Kit (PSK) - Dried Blood Spot for Caffeine Pharmacokinetics Under Microgravity Conditions
The PSK study is preliminary to the study of drug metabolism in space flight conditions. The investigators propose to use simplified blood sampling methods that can be applied in microgravity.
- Conditions
- Drug Mechanism, Metabolism Medication Toxicity, Space Motion Sickness
- Trial name
- PSK (NCT06431984)
- Testing
- prick test
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Pain
Clinical Study to Evaluate Efficacy of New Paracetamol Formulation Compared to Ibuprofen in Headache
The purpose of this multi-center study is to assess the efficacy of headache relief of new paracetamol/caffeine formulation compared to placebo and ibuprofen in episodic tension-type headache (ETTH).
- Trial name
- NCT01842633
- Testing
- Paracetamol and Caffeine, Ibuprofen
- Where
- United States
- Volunteers
- 365 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Depression, Major Depressive Disorder
Remote Evaluation and Alerting for Collaborative Health (REACH) in Depression
Researchers hope to see if the data smartphones collect continuously can be used to predict if patient's depression symptoms will return.
- Trial name
- NCT07174557
- Testing
- MoodTriggers Application
- Where
- 2 sites in United States
- Volunteers
- 320 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Pediatric HIV Infection
Utilizing the HITSystem for Optimizing Paediatric ART Retention and Adherence in Western Nyanza Province, Kenya
Overall, there are an estimated 98,000 children living with HIV in Kenya. Children who are initiated on ART in Kenya and other low resource settings face several challenges with ongoing care due to current limitations of…
- Trial name
- PARA (NCT03980119)
- Testing
- HITSystem 3.0
- Volunteers
- 1,160 people
- Sponsor
- Global Health Innovations
Dermatitis Atopic
An Open-label, DDI Study to Investigate the Effects of Amlitelimab on the PK of Selected Cytochrome P450 Substrates
This is an open-label, single group, 2-period, Phase 1, single-sequence study. The study duration will be up to 342 days. The treatment period will be up to Week 29, where Week 29 is defined as End of Treatment (last amlitelimab…
- Trial name
- NCT06686628
- Testing
- Amlitelimab, Midazolam, Caffeine
- Where
- Germany
- Volunteers
- 23 people
- Sponsor
- Sanofi
Stress, Signs and Symptoms, Digestive
The Acute Effect of Coffee Consumption on Stomach, Self-reported Gastrointestinal Symptoms and Stress.
This study investigated the acute effect of the consumption of four different kinds of coffee (hot and cold instant coffee, cold espresso and hot filter coffee) with the same caffeine content on salivary gastrin, cortisol and…
- Conditions
- Stress, Signs and Symptoms, Digestive, Blood Pressure, Increased Secretion of Gastrin
- Trial name
- NCT02253628
- Testing
- Cold espresso, Hot instant coffee, Cold instant coffee
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Agricultural University of Athens
Muscle Strength, Physical Endurance
Caffeine Supplementation and Strength Endurance in Brazilian Jiu-jitsu Athletes
This study investigated the acute effects of ingesting 400 mg of caffeine administered 30 minutes before Brazilian jiu-jitsu-specific strength endurance tests.
- Conditions
- Muscle Strength, Physical Endurance, Exercise
- Trial name
- CAF-BJJ (NCT07479875)
- Testing
- Caffeine
- Where
- Brazil
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Federal University of Minas Gerais
Mental Fatigue, Cognitive Performance
Phosphatidylserine, Taurine, and Caffeine for Cognitive Fatigue in Professional Football Players
This randomized, double-blind, placebo-controlled, parallel-group trial evaluated neurocognitive fatigue resistance and football-specific decision-making following 28 days of taurine-caffeine supplementation with or without…
- Conditions
- Mental Fatigue, Cognitive Performance, Athletic Performance, Soccer Performance
- Trial name
- TCPS-Foot (NCT07696052)
- Testing
- Taurine Plus Caffeine, Taurine, Caffeine, and Phosphatidylserine
- Where
- 2 sites in Poland
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Vizja University in Warsaw
Breast Reconstruction, Deep Inferior Epigastric Perforator
The Effects of Caffeine on Deep Inferior Epigastric Perforator (DIEP) Flap Perfusion
Women that require breast reconstruction and meet eligibility will be enrolled in this study. The study is being completed to determine the effect of caffeine in deep inferior epigastric perforator (DIEP) flap perfusion using the…
- Conditions
- Breast Reconstruction, Deep Inferior Epigastric Perforator, Microvascular Free Flap Transfer
- Trial name
- NCT04249934
- Testing
- Caffeinated Coffee, DecaffeinatedCoffee
- Where
- United States
- Sponsor
- University of Michigan
Drug Interactions
Validation Study of Multiple Probe Compounds for Drug Interaction Evaluation
The purpose of this study is to identify and validate a probe cocktail for use in future drug-drug interaction studies. Cytochrome P450 enzymes and transport proteins play important roles in the disposition of drugs.
- Trial name
- NCT00964106
- Testing
- Caffeine, Rosiglitazone, Flurbiprofen
- Where
- 2 sites in South Korea
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
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