Clinical trials: Caffeine, completed
Post-Exercise Hypotension, Hypertension
Doses of Coffee and Blood Pressure Response Post-exercise
Introduction: reduction of blood pressure after physical exercise is called post exercise hypotension (PEH). However, previous studies demonstrate that ingestion of caffeine equivalent to three tea-cup of coffee abolishes this…
- Trial name
- NCT02335840
- Testing
- CAF-1, CAF-2, CAF-3
- Volunteers
- 12 people
- Sponsor
- Federal University of Paraíba
Autonomic Nervous System Imbalance
Caffeine and the Autonomic Nervous System
Caffeine consumption has been linked to dysfunction of the autonomic nervous system. In this study the investigators analyze the effects of caffeine containing drinks (including energy drinks and coffee) on ECG based parameters…
- Trial name
- NCT04886869
- Testing
- caffeine
- Where
- Germany
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- LMU Klinikum
Healthy
Coffee, Exercise, and Oxidative Stress
Coffee is one of the most widely consumed beverages. It contains polyphenols (chlorogenic acids) and bioavailability of these bioactive compounds is now somewhat well understood.
- Trial name
- NCT01832701
- Testing
- Coffee
- Where
- Switzerland
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Heart Arrest
Automated Respiration Rate to Improve Accuracy of the Electronic Cardiac Arrest Risk Triage Score (eCART) Algorithm
Currently, breathing rate and heart rate are checked by nursing staff manually every few hours and entered into a patient's medical record.
- Trial name
- NCT02399930
- Testing
- Respiratory & Heart Rate Data Collection
- Where
- United States
- Volunteers
- 133 people
- Sponsor
- University of Chicago
Pulmonary Tuberculoses, Other Specified Pulmonary Tuberculosis
BTZ-043 - Multiple Ascending Dose (MAD) to Evaluate Safety, Tolerability and Early Bactericidal Activity (EBA)
This is a prospective, open label, two-centre, randomized, controlled, two-stage, phase Ib/IIa study to evaluate the safety, tolerability, PK, drug-drug interaction and bactericidal activity of BTZ-043 administered orally once…
- Trial name
- NCT04044001
- Testing
- BTZ-043, Rifafour e-275®, Probe Drug Cocktail
- Where
- 2 sites in South Africa
- Volunteers
- 78 people
- Sponsor
- Michael Hoelscher
Healthy Volunteers
Open-label Study to Evaluate the Effects of NST-1024 on the PK of Multiple Drugs in Healthy Subjects
Phase 1, open label study to evaluate the effects of NST-1024 on the pharmacokinetics (PK) of caffeine (and paraxanthine), flurbiprofen, omeprazole, metoprolol, and midazolam (and 1-hydroxymidazolam) in healthy male and female…
- Trial name
- NCT05368831
- Testing
- NST-1024
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- NorthSea Therapeutics B.V.
Cancer, Pain
Efficacy of Caffeine Injection as an Adjuvant to Opioid Therapy in Cancer Pain
Pain is a most common symptom and it has a high impact on quality of life in cancer patients. Many cancer patients have received opioid therapy, but also many of them have suffered from side effects of opioids.
- Trial name
- NCT00879775
- Testing
- Caffeine, Normal saline
- Where
- 2 sites in South Korea
- Volunteers
- 41 people
- Sponsor
- Korea Research Foundation
Alcohol or Other Drugs Effects
Combined Effects of Alcohol and Caffeine
The purpose of this study is to investigate the effects of caffeine on the self-administration of alcohol. The study will also examine the combined effects of alcohol and caffeine on behavioral performance, participant ratings of…
- Trial name
- NCT01289561
- Testing
- Alcohol + Caffeine Beverage
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Caffeine, Control
Caffeinated Chewing Gum & Wrestling Performance
The purpose of this study was to investigate the effect of caffeinated chewing gum on sympathetic nerve activity on wrestling simulation match.
- Trial name
- NCT06758336
- Testing
- caffeine
- Where
- Taiwan
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- National Taiwan Sport University
Cocaine Related Disorders
Efficacy of Caffeine, With and Without Biperiden, in the Detoxification of Cocaine Dependent Patients
The aim of this study is to assess the efficacy of caffeine compared to placebo in detoxifying cocaine dependent patients. Caffeine potentiation with biperiden will be also studied.
- Trial name
- NCT00495092
- Testing
- Caffeine, Biperiden
- Where
- Spain
- Volunteers
- 85 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Caffeine, Spinal Cord Injury
Influence of Caffeine on HRV and Exercise Performance in Spinal Cord Injury
The aim is to investigate the influence of caffeine on heart rate variability and on performance in a 3 min exercise test in different population groups (able-bodied, paraplegic and tetraplegic subjects).
- Trial name
- NCT02083328
- Testing
- Caffeine
- Where
- Switzerland
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Swiss Paraplegic Research, Nottwil
Refractive Ametropia, Astigmatism
1-Week Dispensing Evaluation of REVIVE™ Toric Soft Contact Lenses
Experienced soft contact lens wearing subjects were enrolled in this 1-week, post-market, bilateral, repeated measures, dispensing study.
- Trial name
- NCT06053736
- Testing
- REVIVE Toric Soft Contact Lenses
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Bausch & Lomb Incorporated
Obesity
The Effect of Circadian Timing Program on Obesity Management and Sleep Quality
This study, it was aimed to examine the effect of circadian timing program created for obese individuals with evening chronotype on obesity management and sleep quality.
- Trial name
- NCT04665336
- Testing
- Circadian Timing Program, Sleep Hygiene Training
- Where
- Turkey (Türkiye)
- Volunteers
- 38 people
- Sponsor
- Kocaeli University
Human Immunodeficiency Virus
Plan and Pledge, HIV Self-testing in South Africa
The Plan and Pledge pilot will incorporate behavioral economics approaches (nudges) into the pre-existing STAR self-test fixed-site distribution program, implemented by Wits Reproductive Health and HIV Institute (Wits RHI) at the…
- Trial name
- NCT03898557
- Testing
- Provision of HIV self-test with Commitment and planning prompts, Provision of HIV self-test
- Where
- United States
- Volunteers
- 1,479 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Healthy Volunteers
Cocktail Approach for Cytochrome P450 and P-glycoprotein Activity Assessment Using Dried Blood Spot
Phenotyping is an approach largely used for the evaluation of the activity of cytochromes and transporters in vivo. It consists of the administration of probe substances metabolised by a specific cytochrome or transported by…
- Trial name
- NCT01731067
- Testing
- Cocktail probe drugs
- Where
- Switzerland
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Jules Desmeules
Pain, Postoperative
Caffeine and Neurologic Recovery Following Surgery and General Anesthesia
The ongoing opioid epidemic is a public health crisis, and surgical patients are particularly vulnerable to opioid-dependency and related risks. Emerging data suggest that caffeine may reduce pain after surgery.
- Trial name
- NCT03577730
- Testing
- Caffeine Citrate, Dextrose Water
- Where
- United States
- Volunteers
- 71 people
- Sponsor
- University of Michigan
Healthy Adults
Ketone Production With Acute Caffeine Intake
Evaluate the effect of a caffeine supplement on the stimulation of lipolysis and the production of ketones in healthy adults (N=10).
- Trial name
- NCT02694601
- Testing
- Control, Caffeine low dose, Caffeine high dose
- Where
- Canada
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Université de Sherbrooke
Healthy
Effects of ElevATP on Body Composition and Athletic Performance
This study will examine the effects of supplemental ElevATP with or without a blend of extended-release caffeine and B vitamins for changes in body composition, athletic performance, and hematology over a 12 week intervention…
- Trial name
- NCT02819219
- Testing
- Supplemental, Exercise Intervention
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- MusclePharm Sports Science Institute
Caffeine
Caffeine, Resistance Exercise and EMG
Introduction: Several studies have evaluated and confirmed the ergogenic effects of acute caffeine intake on sports performance.
- Trial name
- NCT06606652
- Testing
- Caffeine
- Where
- Spain
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Alcala
Sleep Disorders, Sleep Apnea, Obstructive
Sleep Disorders Management, Health and Safety in Police
The purpose of the study is to test the effect of a sleep disorders detection and treatment program for police officers on their safety, quality of life, and job performance. The program is called Operation Healthy Sleep.
- Conditions
- Sleep Disorders, Sleep Apnea, Obstructive, Restless Legs Syndrome, Sleep Disorders, Circadian Rhythm
- Trial name
- NCT00207285
- Testing
- Sleep Hygiene Education, Screening and Treatment of Sleep Disorders
- Where
- United States
- Volunteers
- 731 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital