CaffeineNCT06758336
Caffeinated Chewing Gum & Wrestling Performance
A study testing caffeine in people with Caffeine and Control, run by National Taiwan Sport University at 1 site in Taiwan.
Trial summary
The purpose of this study was to investigate the effect of caffeinated chewing gum on sympathetic nerve activity on wrestling simulation match. Read more about this study
- Who is it for?
- Ages 20 to 40 years, men onlyHealthy volunteers can take part
- What is being tested?
- caffeine
- Could I receive a placebo?
- Yes, some participants may receive a placebo
- How many people
- 16 participants
- Where
- 1 siteTaiwan
- Study dates
- 11 Jun 2024to 23 Dec 2024
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 20 to 40 years
- Men only
- Healthy volunteers accepted
- Adult
Who may be able to join
- more than 6years of professional wrestling training;
- more than 6 months of continuous training;
- recovering from sports injuries such as strains and contusions for at least 3 months.
Who cannot join
- non-professionally wrestling athlete;
- none regular training in the past 6 months;
- less than 3 months of recovery from a sports injury, or present epilepsy, hypertension, hyperlipidemia, heart disease, arthritis, osteoporosis, or brain injury;
- a history of caffeine allergy.
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Caffeinated Chewing Gum Improves Sympathetic Nerve Activity and Simulates Wrestling Performance: a Double-blind Crossover Trial
The purpose of this study was to investigate the effect of caffeinated chewing gum on sympathetic nerve activity on wrestling simulation match.
Read the detailed description
The purpose of this study was to investigated whether caffeine intake is effective in improving the performance of wrestlers in a simulated competition. The study was designed to involve 16 healthy adult male athletes who had been trained in professional wrestling and were divided into caffeine trial (CAF trial) and placebo trial (PL trial) in a randomized crossover double-blind study design. After three days of dietary control, participants arrived at the laboratory in the afternoon of the day of the trial to collect saliva samples in a quiet state and were fitted with a heart rate monitor. Participants chewed either caffeine-containing gum at 3 mg/kg body weight (CAF trial) or placebo-containing gum without caffeine (PL trial) for 10 minutes and then spit it out. Participants then underwent a 15-minute dynamic warm-up. At the end of the warm-up, participants performed 2 rounds of 3-minute wrestling-specific simulated matches, and the number of falls in the simulated matches was recorded. After the simulation match, saliva samples were collected from the participants again. The saliva samples were analyzed for caffeine alpha-amylase concentration. Differences between the two trials were analyzed using a paired sample t-test and significance was set at α<0.05.
- Being tested
- caffeine
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
caffeineDietary supplement
The participants chewing either caffeine Gum (CAF trial, containing 3 mg/kg of caffeine) for 10 minutes. After rested for 15 minutes, the participants underwent tests.
| Study group | Role | What they receive |
|---|---|---|
| caffeine gum | Experimental | The participants chewing caffeine gum 10 minutes before exercise Receives: Dietary Supplement: caffeine |
| placebo gum | Placebo comparator | The participants chewing placebo gum 10 minutes before exercise Receives: Dietary Supplement: caffeine |
What is being measured
The primary outcome is the main question the study is designed to answer.
The number of falls in the simulated matches
Record number of falls in the simulated matches
Measured: 15 minutes after intervention
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted3 Jan 2025
- Study start11 Jun 2024
- Primary completion30 Jun 2024
- Study completion23 Dec 2024
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for CaffeineStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Crossover
- Model description
- a randomized crossover double-blind study design
- Masking
- Double blind
- Who is masked
- Participant, Investigator
- Enrolment
- 16 participants (actual)
Sponsor and investigators
- Lead sponsor
- National Taiwan Sport University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Chih-Hui Chiu, National Taiwan Sport University
- Investigators
- Chih-Hui Chiu, PhD, Principal investigator, Sport Science Research Center
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06758336
- Sponsor's protocol ID
- 113-9
- Status last verified
- Dec 2024
- First submitted
- 26 Dec 2024
- Last updated
- 3 Jan 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No: No IPD sharing plan
Study at a glance
From the registry record, last updated by the sponsor on 3 Jan 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Caffeinated Chewing Gum Improves Sympathetic Nerve Activity and Simulates Wrestling Performance: a Double-blind Crossover Trial
- ClinicalTrials.gov ID
- NCT06758336
- Acronym / sponsor ID
- 113-9
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 16 participants (actual)
- Lead sponsor
- National Taiwan Sport UniversityUniversity, hospital or other
- Study start
- 11 Jun 2024 (actual)
- Primary completion
- 30 Jun 2024 (actual)
- Study completion
- 23 Dec 2024 (actual)
- First posted
- 3 Jan 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The purpose of this study was to investigate the effect of caffeinated chewing gum on sympathetic nerve activity on wrestling simulation match.
Detailed description
The purpose of this study was to investigated whether caffeine intake is effective in improving the performance of wrestlers in a simulated competition. The study was designed to involve 16 healthy adult male athletes who had been trained in professional wrestling and were divided into caffeine trial (CAF trial) and placebo trial (PL trial) in a randomized crossover double-blind study design. After three days of dietary control, participants arrived at the laboratory in the afternoon of the day of the trial to collect saliva samples in a quiet state and were fitted with a heart rate monitor. Participants chewed either caffeine-containing gum at 3 mg/kg body weight (CAF trial) or placebo-containing gum without caffeine (PL trial) for 10 minutes and then spit it out. Participants then underwent a 15-minute dynamic warm-up. At the end of the warm-up, participants performed 2 rounds of 3-minute wrestling-specific simulated matches, and the number of falls in the simulated matches was recorded. After the simulation match, saliva samples were collected from the participants again. The saliva samples were analyzed for caffeine alpha-amylase concentration. Differences between the two trials were analyzed using a paired sample t-test and significance was set at α<0.05.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Crossover
- Masking
- Double blind (participant, investigator)
- Number of arms
- 2
- Model description
- a randomized crossover double-blind study design
| Arm | Type | Receives |
|---|---|---|
| caffeine gum | Experimental | Dietary Supplement: caffeineThe participants chewing caffeine gum 10 minutes before exercise |
| placebo gum | Placebo comparator | Dietary Supplement: caffeineThe participants chewing placebo gum 10 minutes before exercise |
Who may qualify
- Ages
- 20 to 40 years
- Sex
- Male only
- Healthy volunteers
- Accepted
- Age groups
- Adult
Key inclusion criteria (3 listed)
- more than 6years of professional wrestling training;
- more than 6 months of continuous training;
- recovering from sports injuries such as strains and contusions for at least 3 months.
Key exclusion criteria (4 listed)
- non-professionally wrestling athlete;
- none regular training in the past 6 months;
- less than 3 months of recovery from a sports injury, or present epilepsy, hypertension, hyperlipidemia, heart disease, arthritis, osteoporosis, or brain injury;
- a history of caffeine allergy.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| caffeineThe participants chewing either caffeine Gum (CAF trial, containing 3 mg/kg of caffeine) for 10 minutes. After rested for 15 minutes, the participants underwent tests. | Dietary supplement | caffeine gum, placebo gum |
Primary outcome
The number of falls in the simulated matches
Time frame: 15 minutes after intervention
Record number of falls in the simulated matches
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 3 Jan 2025.
- Individual participant dataSharing planned: No. No IPD sharing plan
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Chih-Hui Chiu, PhD principal investigator
Sport Science Research Center
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing caffeine in people with Caffeine and Control, run by National Taiwan Sport University at 1 site in Taiwan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 3 Jan 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Taiwan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. Some participants in this study may receive a placebo. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
The number of falls in the simulated matches (time frame: 15 minutes after intervention). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 3 Jan 2025.