Clinical trials: Caffeine
Pain, Chronic Pain
The Effects and Mechanisms of Brief Mindfulness Meditation and Hypnosis for Pain
The aim of this study is to determine the effects and mechanisms of 1 x 20-min training in mindfulness meditation and self-hypnosis relative to an inert control. Participants will be randomly assigned to condition.
- Trial name
- NCT05323383
- Testing
- Mindfulness Meditation, Self-hypnosis, Attention Control
- Where
- Australia
- Volunteers
- 300 people
- Sponsor
- The University of Queensland
Healthy
To Determine Blood Concentrations of Ibuprofen and Caffeine in a Tablet Against Ibuprofen Alone From Another Tablet
The objective of the trial is to compare to combination of 400 mg ibuprofen and 100 mg caffeine against 400 mg ibuprofen alone under fed conditions
- Trial name
- NCT02629354
- Testing
- Ibuprofen, Caffeine
- Where
- South Africa
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Nutrition Processes
Effects of Nutraperf Consumption in Runners
Exercise has numerous health benefits. Nevertheless, when exercise duration is ~45 min or longer and intensity moderate to intense, it may induce different troubles, for example: hypoglycemia, peripheral and central fatigue…
- Trial name
- NCT00799630
- Testing
- Carbohydrate drink
- Where
- France
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Lescuyer Laboratory
Energy Drinks
The Effect of Energy Drinks Consumption on Acute Physiological and Psychological Responses of Israeli Arab Adolescents
Quasi-experiment and Cross-sectional study, six-arm design protocol will be carried out. The study will be conducted under the Declaration of Helsinki.
- Trial name
- EDE (NCT04808128)
- Testing
- Drink A + SC, Drink B + SC, Drink C + SC
- Where
- Israel
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Tel Hai College
Supplementation, Sports Nutrition
Caffeine Kinetics and CrossFit®-Specific Performance
The study aims at assessing the relation between caffeine (CAF) and paraxanthine (PAX) kinetics after acute ingestion of caffeine (3 mg/kg body mass) in the form or mono- or multi-ingredient preparations and CrossFit®-specific…
- Conditions
- Supplementation, Sports Nutrition, Ergogenic Support, Discipline-specific Performance
- Trial name
- NCT05516212
- Testing
- CAFMONO supplementation, CAFMIPS_1 supplementation, CAFMIPS_2 supplementation
- Where
- Poland
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Poznan University of Physical Education
CYP1A2 Polymorphism
Personalized Nutrition Caffeine Intake in Healthy Adults.
Personalized nutrition is one of the most up to date trends in human nutrition and gains much interest of general public and scientists as well.
- Trial name
- NCT04122053
- Testing
- Intervention group with genotype information, Control group without genotype information
- Where
- Poland
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Poznan University of Life Sciences
Dialysis; Complications, Wound Complication
A Novel Device for Surveillance of Vascular Access Sites for Bleeding
Background Bleeding is often encountered after vascular access procedures for dialysis and fatal episodes of haemorrhage has been reported.
- Conditions
- Dialysis; Complications, Wound Complication, Catheter Complications, Hemorrhage
- Trial name
- NCT04285775
- Testing
- Application of device which monitors for bleeding - Blood Warning Technology with Continuous Hemoglobin sensor (BWATCH)
- Where
- Singapore
- Volunteers
- 250 people
- Sponsor
- Changi General Hospital
Noise Exposure
Broadband Sound and Sleep
Sound insulation of bedrooms is expensive and typically only granted to residents living close to the airport. We plan to investigate the effects of various aviation noises on sleep under controlled laboratory conditions and to…
- Trial name
- NCT05774977
- Testing
- Aviation Noise Only (AN), Pink noise only, 50 dBA (BN50), Aviation Noise With Earplugs (AN+EP)
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Incontinence
The Integration of Sensor Technology Into Incontinence Materials: a Single-group Pretest-posttest Study in a Nursing Home Environment
The smart diaper aims to (1) detect humidity, (2) be capable of sending real-time indication of the saturation to the healthcare workers when urine loss occurs and (3) generate alerts when the diaper requires changing.
- Trial name
- Smart Diapers (NCT05316012)
- Testing
- Smart diapers
- Where
- Belgium
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University Ghent
Postoperative Ileus
Does Caffeine Enhance Bowel Recovery After Colorectal Surgery?
Postoperative ileus is a frequently occurring surgical complication. It is defined as temporary inhibition of propulsive bowel activity and is manifested by abdominal distention, nausea, vomiting and diet intolerance.
- Trial name
- NCT03097900
- Testing
- Caffeine Citrate, Water
- Where
- Israel
- Volunteers
- 70 people
- Sponsor
- Hadassah Medical Organization
Prehypertension
Study of the Effects of an Oral Nitric Oxide Supplement on Blood Pressure in Prehypertensive Adults
Oral supplementation of Neo40(TM), a nitrate lozenge, will reduce blood pressure in healthy adults with clinical prehypertension.
- Trial name
- NCT01937754
- Testing
- Nitric Oxide supplement
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Neogenis Laboratories
Coronavirus Disease 2019
1,3,7-Trimethylxanthine as a Treatment of COVID-19: Results of a Controlled Study
This is observational study to assess the prognosis of patients hospitalized with COVID-19 confirmed by RT-PCR and exposed to trimethylxanthine (TMX). Trimethylxanthine is the active molecule present in coffee.
- Trial name
- TMX COVID (NCT04395742)
- Testing
- Data collection
- Volunteers
- 93 people
- Sponsor
- Poitiers University Hospital
Female Sexual Arousal Disorder
Examining Caffeine as a Treatment for Antidepressant-induced Arousal Dysfunction in Women
Antidepressants have negative effects on genital arousal function that hinder quality of life and jeopardize medication adherence.
- Trial name
- NCT05685407
- Testing
- Caffeine
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Texas at Austin
Respiratory Disease, COVID-19
REVIVe: Frailty, Rehabilitation, and Outcomes in Critically Ill Adult and Pediatric Survivors of COVID-19 or ARI
Background: Many adults and some children with COVID-19 or acute respiratory infection become critically ill and need advanced life support in the Intensive Care Unit (ICU).
- Conditions
- Respiratory Disease, COVID-19, Viral Infection
- Trial name
- REVIVe (NCT05246098)
- Where
- 26 sites in Canada
- Volunteers
- 679 people
- Sponsor
- McMaster University
Healthy
Coffee Consumption, the Gut Microbiome, and the Microbiota-Gut-Brain Axis
The aim of this study is to investigate the potential of coffee to act as a prebiotic to alter gut microbiota and improve mood, memory and cognitive performance.
- Trial name
- NCT05927038
- Testing
- Caffeinated coffee, Decaffeinated coffee
- Where
- Ireland
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University College Cork
the Severity and Duration of Intraoperative Hypotension
HPI in Older Patients Undergoing Major Gastrointestinal Surgery
The incidence of intraoperative hypotension was 91%. The increasing incidence of intraoperative hypotension would increase the risk of postoperative complications, such as postoperative arrythmia, stroke or acute kidney injury.
- Trial name
- NCT05297318
- Testing
- hypotension prediction index guided, without hypotesion prediction index guided
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- National Taiwan University Hospital
Sickle Cell Disease
Drug Interaction Study of GBT440 With Caffeine, S-warfarin, Omeprazole, and Midazolam in Healthy Subjects
The purpose of this study to evaluate the effect of concomitant administration of GBT440 on caffeine (a CYP1A2 probe substrate), S warfarin (a CYP2C9 probe substrate), omeprazole (a CYP2C19 probe substrate), and midazolam (a…
- Trial name
- NCT02567682
- Testing
- GBT440
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Global Blood Therapeutics
Apnea of Prematurity
Inhalation of Low Concentration of CO2 in Preterm Infants Not Responding to Caffeine for the Treatment of Apnea
In premature infants, apnea of prematurity is one of their major clinical problems. Caffeine is currently a worldwide therapy to reduce the number and severity of these apneas.
- Trial name
- NCT01911182
- Testing
- Inhalation of low concentration of CO2
- Where
- Canada
- Volunteers
- 7 people
- Sponsor
- University of Manitoba
Diabetes Mellitus, Type 2
Quitting Caffeine for Better Glucose Metabolism
This project is a pilot study of caffeine abstinence in coffee-drinkers who have type 2 diabetes. Evidence suggests that caffeine may impair the control of glucose levels, especially in those people who have type 2 diabetes.
- Trial name
- NCT01030796
- Testing
- Caffeine abstinence
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Sexual Behavior
Effects of Caffeine on Women's Sexual Arousal
The key research question in this study is whether or not caffeine facilitates genital sexual arousal in women in the presence of an external erotic stimulus.
- Trial name
- NCT01242046
- Testing
- Caffeine
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Texas at Austin
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