Clinical trials: Caffeine, completed
Myocardial Infarction
Coronary Care Caffeine: Influence of Coffee on Heart Rate Post Myocardial Infarction
Sudden cardiac death due to a heart rhythm disturbance after a heart attack (myocardial infarction) is a common cause of death. It is well documented that sudden cardiac death after a myocardial infarct (MI) is associated with…
- Trial name
- NCT00137098
- Testing
- Caffeine
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- The Royal Bournemouth Hospital
Healthy
Effects of Acute Intake of Flavanols on Cerebral Oxygenation and Cognition in Young Male Adults
The study evaluates the impact of one acute dose of cocoa flavanols on brain oxygenation during a hypercapnia challenge, as well as impact on cognitive performance in young healthy males.
- Trial name
- NCT04374409
- Testing
- High-flavanol cocoa powder, Low-flavanol cocoa powder
- Where
- United Kingdom
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Birmingham
Obesity, Weight Loss
Changes in Gut Hormones, Body Composition and Energy Expenditure After Roux-en-Y
The purpose of this study is to gain a better understanding of the mechanism of weight regain through gut hormone (substances in the gut that control various functions of the digestive organs) and energy expenditure (the amount…
- Trial name
- NCT02048501
- Testing
- Resting Metabolic Rate (RMR), Duel-energy x-ray absorptiometry (DEXA), Visual Analog Scale (VAS)
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- Duke University
Essential Hypertension, Sleep Quality
Sleep Hygiene Education and Blood Pressure Control in Essential Hypertension in Primary Care
This randomized controlled trial evaluated the effect of a brief sleep hygiene education program on sleep quality and blood pressure in adults with essential hypertension attending a family practice center in southern Türkiye.
- Conditions
- Essential Hypertension, Sleep Quality, Primary Care
- Trial name
- NCT07257237
- Testing
- Sleep hygiene education program
- Where
- Turkey (Türkiye)
- Volunteers
- 138 people
- Sponsor
- Ozturk Gurer Tutu, MD
Type1diabetes, Type1 Diabetes Mellitus
Evaluation of Coffee Therapy for Improvement of Renal Oxygenation
Over 1.25 million Americans have Type 1 Diabetes (T1D), increasing risk for early death from cardiovascular disease (CVD). Despite advances in glycemic and blood pressure control, a child diagnosed with T1D is expected to live up…
- Conditions
- Type1diabetes, Type1 Diabetes Mellitus, Diabetic Kidney Disease, Juvenile Diabetes
- Trial name
- COFFEE (NCT03878277)
- Testing
- Starbucks® Cold brew - 325ml bottle
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Colorado, Denver
Athletic Performance, Cognitive Performance
Effects of Different Doses of Caffeine on Physical and Cognitive Performance in Female Handball Players
This study investigates how different doses of caffeine affect physical and cognitive performance in female handball players. Caffeine is widely used as a performance-enhancing substance, but its effects may vary depending on the…
- Conditions
- Athletic Performance, Cognitive Performance, Healthy Adult Females
- Trial name
- NCT07562256
- Testing
- Caffeine 3 mg/kg, Caffeine 6 mg/kg
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Sinop University
Nocturia
The Effect of Combined Systematized Behavioural Modification Education Program (SyBeMeP) With DDAVP in Patients With Nocturia
In patients with nocturia, combinational treatment of DDAVP and SyBeMeP might show better outcomes. Systemic video instruction might prove to be beneficial by helping patients have better understanding on treatment and replacing…
- Trial name
- NCT01576900
- Testing
- SyBeMeP (Systemized Behavioural Modification education Program)
- Where
- South Korea
- Volunteers
- 124 people
- Sponsor
- Seoul National University Hospital
Hepatitis C, Chronic
Drug Drug Interaction Study Between BI 201335 and BI 207127 in Chronic Hepatitis C Infected Patients
To evaluate the drug-drug interactions between BI 201335 and BI 207127 as well as their combined effect on CYP probe drug substrates and on tenofovir and raltegravir in treatment naive or prior treatment relapse patients with…
- Trial name
- NCT01525628
- Testing
- midazolam, BI 201335, tenofovir
- Where
- 16 sites in United States, Canada and 1 more
- Volunteers
- 72 people
- Sponsor
- Boehringer Ingelheim
Pain, Postoperative, Tooth Diseases
Efficacy and Safety of Ibuprofen and Caffeine in Dental Pain
The primary objective of this study is to compare the efficacy of a combination product containing ibuprofen 400 mg and caffeine 100 mg versus either ingredient alone as well as placebo for the treatment of post-surgical dental…
- Trial name
- NCT01929031
- Testing
- ibuprofen + caffeine, ibuprofen, caffeine
- Where
- United States
- Volunteers
- 562 people
- Sponsor
- Boehringer Ingelheim
Apnea of Prematurity, Caffeine
Target Weaning Oxygen to Determine Cafffeine Duration for AOP
Caffeine, a typical representative of methylxanthine, is world-widely used to manage apnea of prematurity (AOP) in neonatology. However, an appropriate medication regimen of caffeine has not been well defined until now.
- Conditions
- Apnea of Prematurity, Caffeine, Weaning Oxygen, Medicine Regimen
- Trial name
- DCAP (NCT04868565)
- Testing
- Caffeine Citrate 20 MG/1 ML Intravenous Solution [CAFCIT]
- Where
- 41 sites in China
- Volunteers
- 310 people
- Sponsor
- Children's Hospital of Chongqing Medical University
Overweight, Obesity
Efficacy of a Tea Catechin Sports Drink for Enhancing Exercise-Induced Fat Loss
The primary objective of this trial is to evaluate the influence of consuming a tea catechin containing sports beverage on body fat mass during exercise-induced weight loss among overweight and obese men and women.
- Trial name
- NCT00692731
- Testing
- 500 mL/day of a beverage providing approximately 625 mg catechins, Control beverage matched for energy and caffeine content
- Where
- 2 sites in United States
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Provident Clinical Research
Caffeine, Placebo
Caffeinated Chewing Gum on Special Forces Performance
The purpose of this project is to investigate the effects of caffeine chewing gum on the cognitive functions and special operations capabilities of special forces.
- Trial name
- NCT06638372
- Testing
- caffeine
- Where
- Taiwan
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- National Taiwan Sport University
Glaucoma, Primary Open Angle
Caffeine Consumption in Glaucoma Patients and Healthy Subjects
Caffeine is the most widely consumed drinking nutrient in the world. Caffeine effects various organs and the vascular system. It decreases ocular blood flow due to vasoconstriction.
- Trial name
- NCT03675412
- Testing
- Caffeine tablet
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Wills Eye
Healthy Volunteers
Dabigatran in an Interaction Probe Drug Cocktail
Four periods of oral dosing following overnight fasting (1. known metabolic probe drug cocktail consisting of caffeine, diclofenac, esomeprazole, metoprolol, midazolam; 2. dabigatran + cocktail; 3. dabigatran alone; 4.
- Trial name
- D-cocktail (NCT02361619)
- Testing
- Caffeine, Diclofenac, Esomeprazole
- Where
- Finland
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Turku University Hospital
Effects of Turkish Coffee Consumption on Cardiovascular Markers and Sleep in Healthy Women, Cardiometabolic Health Markers, Appetite-regulating Hormones, Inflammation, and Sleep Quality in Healthy Women
Effects Of Turkish Coffee Consumption On Cardiovascular Markers And Sleep In Healthy Women
This randomized controlled trial aims to evaluate the short-term effects of daily unfiltered Turkish coffee consumption on cardiovascular parameters, appetite-regulating hormones, glucose metabolism, inflammatory markers, and…
- Trial name
- TURCOFFEE (NCT07133373)
- Testing
- Turkish Coffee (unfiltered, boiled)
- Where
- Jordan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Petra
Irritable Bowel Syndrome
Low FODMAPs Diet vs. Specific Dietary Advice in Patients With IBS Diarrheal Variant
A reduced content of FODMAPs (fermentable oligosaccharides, disaccharides, monosaccharides, and polyols) in the diet may be beneficial for patients with IBS diarrheal variant, but so far few randomized trials have reported data…
- Trial name
- DIETSINIBS (NCT03423069)
- Testing
- Diet low in FODMAPs, Specific dietary advice for IBS
- Where
- Italy
- Volunteers
- 62 people
- Sponsor
- Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis
Intermittent Claudication
Caffeine and Intermittent Claudication
The purpose of this study is to evaluate the change in Walking capacity after an intake of caffeine. The study design is cross-over and follow-up of 80 patients with leg pain caused by narrowing of their leg arteries, Peripheral…
- Trial name
- NCT00388128
- Testing
- Caffeine 6mg/kg
- Where
- Denmark
- Volunteers
- 80 people
- Sponsor
- University of Aarhus
Performance of Colonoscopy, Tolerance of Colonoscopy
Abdominal Binder in Colonoscopies Performed by Trainees
This randomized trial will be conducted to evaluate the effectiveness and safety of an abdominal binder use during colonoscopy performed by gastrointestinal endoscopy fellow trainees.
- Trial name
- NCT05617521
- Testing
- Abdominal binder (Revive 3-in-1 Postpartum Recovery Support Belt), Loose abdominal binder (Revive 3-in-1 Postpartum Recovery Support Belt)
- Where
- Mexico
- Volunteers
- 211 people
- Sponsor
- Hospital Central Norte PEMEX
Healthy
The Effects of Caffeine on Pain-Based Pacing During a Cycling Time-Trial
Caffeine has been shown to consistently improve time-trial performance, warranting restrictions on consumption under regulation of the National Collegiate Athletics Association (NCAA) and World Anti-Doping Agency (WADA).
- Trial name
- NCT02115763
- Testing
- Caffeine
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Neutrophil Chemotactic Response
Influence of Lifestyle Factors on Neutrophil Migration Pilot Study
This study will determine how common lifestyle practices affect the behavior of neutrophils (a type of immune cell) at shorter time scales than previously possible.
- Trial name
- NCT02411318
- Testing
- Exercise, ProLab 200mg caffeine capsule, Ethanol ingestion
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison