Clinical trials: Caffeine, completed
Caffeine, Placebo
Caffeinated Chewing Gum on 400-meter Performance
20 trained sprinter were divided into caffeine Gum trial (CAF) and Placebo trial (PL) with a randomized, double-blind study design.
- Trial name
- NCT06430996
- Testing
- caffeine
- Where
- Taiwan
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Chih-Hui Chiu
Caffeine, Placebo
Caffeine & Bodybuilding Dehydration Ability
15-20 trained bodybuilding athletes were divided into caffeine gum trial (CAF) and placebo trial (PL) with a randomized, double-blind study design.
- Trial name
- NCT06431035
- Testing
- caffeine
- Where
- Taiwan
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Chih-Hui Chiu
Syncope, Vasovagal
The Effect of CPC on Aborting Tilt Induced Syncope in Patients With a History of Vasovagal Syncope or Near Syncope
Syncope is defined as transient loss of consciousness associated with inability to maintain postural tone with rapid and spontaneous recovery.
- Trial name
- NCT04972123
- Testing
- CPC - Capsaicin, Phenylephrine, Caffeine, Tilt Table Test
- Where
- United States
- Volunteers
- 143 people
- Sponsor
- University of Wisconsin, Madison
Neuroendocrine Tumors
Investigation of the Effects of Diet on the Measurement of Plasma Chromogranin in NET Patients
Measurement of plasma chromogranin A remains the most commonly used biomarkers for both screening and monitoring of patients with gastro-entero-pancreatic neuroendocrine tumours (GEP-NET), despite several limitations that…
- Trial name
- DIB-NET (NCT03288402)
- Testing
- ongoing fasted state, intake of caffeine containing beverages or 5-item English breakfast
- Where
- United Kingdom
- Volunteers
- 346 people, healthy volunteers welcome
- Sponsor
- University Hospitals Coventry and Warwickshire NHS Trust
Energy Expenditure, Cognition
A Randomized Study to Examine the Ability of a Caffeine-Based Energy Drink to Impact Energy Expenditure, Fat Oxidation, Reaction Time, and Other Perceptual Indicators
The purpose of this study is to evaluate the changes in energy expenditure, fat oxidation, reaction time, and perceptual indicators of energy and focus after acute ingestion of a caffeine-based energy drink.
- Conditions
- Energy Expenditure, Cognition, Reaction Time
- Trial name
- ASH (NCT05998096)
- Testing
- Caffeine-Based Energy Drink
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Lindenwood University
Healthy Participants
A Study to Estimate the Effect of Multiple Dose Abrocitinib on Caffeine, Efavirenz, and Omeprazole in Healthy Participants
This is a Phase 1, open-label, multiple dose, single fixed-sequence, 2-period study to evaluate the effect of abrocitinib on the pharmacokinetics (PK) of caffeine, efavirenz and omeprazole in healthy adult participants.
- Trial name
- NCT05067439
- Testing
- Abrocitinib, Omeprazole, Caffeine
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Pfizer
Supplementation, Sports
The Influence of Caffeine Supplementation on Specific Performance and Training Activities
The purpose of this study is to verify the effect of acute caffeine (CAF) and placebo (PLA) supplementation on physical capacity and discipline-specific exercise performance in athletes, in a randomised, double-blind…
- Trial name
- NCT03822663
- Testing
- Caffeine supplementation
- Where
- Poland
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Poznan University of Physical Education
Muscle Power
Effects of Caffeine-based Supplement on Physical Performance
The aim of the study was to determine the acute effects of multi-ingredient pre-workout supple-ment (MIPS) containing: beta-alanine, taurine, caffeine, L-tyrosine, and cayenne pepper (capsaicin) on physical performance in…
- Trial name
- NCT06363669
- Testing
- multi-ingredient pre-workout dietary supplement (caffeine-based)
- Where
- Poland
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University School of Physical Education, Krakow, Poland
Inguinal Hernia
Awake Caudal Catheter vs General Anesthesia
It is well established that preterm inguinal hernias discovered in the NICU pose a significant surgical risk due to the associated co-morbid conditions that accompany these patients.
- Trial name
- NCT05919732
- Testing
- Bupivacaine, Dexmedetomidine, Caffeine, Tylenol, Propofol, rocuronium, caffeine, Tylenol, bupivacaine
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Nemours Children's Clinic
Caffeine
Effects of Caffeinated Gum on a Basketball-specific Tests in Basketball Players
This study investigated the effects of chewing 3 mg/kg of caffeinated gum on basketball free throw accuracy and basketball -specific performance.
- Trial name
- NCT06016985
- Testing
- caffeine gum
- Where
- Taiwan
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Chih-Hui Chiu
Adult Population
The Acute Effects of Caffeine on Exercise and Cognition
The effects of moderate intensity aerobic exercise and caffeine ingestion on cognition (more specifically working memory) in non-caffeine drinker and caffeine drinkers will be examined.
- Trial name
- AEC (NCT03400423)
- Testing
- Caffeine, Moderate Intensity Exercise
- Where
- Canada
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Western University, Canada
Acute Exercise, Caffeine Withdrawal
The Acute Effects of Exercise and Caffeine on Working Memory During Acute Caffeine Deprivation
To determine the effects of moderate intensity exercise and caffeine on working memory in deprived caffeine consumers.
- Conditions
- Acute Exercise, Caffeine Withdrawal, Memory Deficits
- Trial name
- NCT05170464
- Testing
- Acute Exercise, Caffeine Powder
- Where
- Canada
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Western University, Canada
Caffeine, Adaptation
The Turkish Version Of The Brief-Caffeine Expectancy Questionnaire
Caffeine is a psycho-active substance that is widely consumed in the world. It is seen that its widespread consumption is related to expectancies of consumption as well as cultural factors.
- Conditions
- Caffeine, Adaptation, Expectations, Language
- Trial name
- NCT06038903
- Testing
- caffeine consumption expectation
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Eskisehir Technical University
Fatigue
"WakeUp" for Vigilance Following Lunch
This is a single center, double-blind, placebo and active controlled clinical trial comprised of a single drink of WakeUp beverage (in 3 doses) compared to Caffeine (100mg) and placebo given to health volunteers.
- Trial name
- NCT04685005
- Testing
- "Wake Up", Caffeine
- Where
- Israel
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Carmel Medical Center
Caffeine, Burning Mouth Syndrome
Caffeine vs. ALA in BMS Treatment. (BMS: Burning Mouth Syndrome. ALA: Alpha-Lipoic Acid.)
The aim of this study was to evaluate the efficacy of caffeine and alpha-lipoic acid in the treatment of burning mouth syndrome by symptom assessment with visual analogue scale.
- Trial name
- NCT06195137
- Testing
- Caffeine, Alpha Lipoic Acid
- Where
- China
- Volunteers
- 130 people
- Sponsor
- Lu Jiang
HIV Infections
Evaluation of Pharmacokinetic Interaction Between GSK3640254 and Caffeine, Metoprolol, Montelukast, Flurbiprofen, Omeprazole, Midazolam, Digoxin, and Pravastatin in Healthy Adults
This is an open-label, single sequence study that is being conducted to investigate the potential drug-drug interaction (DDI) when GSK3640254 is co-administered with a cocktail of cytochrome P450 (CYP) enzymes and transporter…
- Trial name
- NCT04425902
- Testing
- GSK3640254 200 mg, Caffeine 200 mg, Metoprolol 100 mg
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- ViiV Healthcare
Headache, Pregnancy Related
Acute Headache Treatment in Pregnancy: Occipital Nerve Block vs PO Acetaminophen With Caffeine
This is an open label randomized controlled trial evaluating response to bupivacaine occipital nerve block compared to Tylenol/Caffeine cocktail in treatment of pregnant patients seeking care of headache.
- Conditions
- Headache, Pregnancy Related, Occipital Nerve Block
- Trial name
- NCT03951649
- Testing
- Occipital Nerve Block
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Spinal Cord Injuries
Effects of Caffeine and Intermittent Hypoxia on Leg Function in Human Spinal Cord Injury
Accumulating evidence suggests that repeatedly breathing low oxygen levels for brief periods (termed intermittent hypoxia) is a safe and effective treatment strategy to promote meaningful functional recovery in persons with…
- Trial name
- NCT02323698
- Testing
- Caffeine, AIH
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Spaulding Rehabilitation Hospital
Hemodynamics, Caffeine
Improving Cognition With Neurodegradation Countermeasure
The goal of this randomized, placebo-controlled, three-condition, double-blind, within-participants crossover clinical trial is to compare caffeine, TeaCrine plus caffeine, and a placebo condition in ROTC or tactical personnel.
- Conditions
- Hemodynamics, Caffeine, TeaCrine, Cognitive Change
- Trial name
- NCT05715073
- Testing
- TeaCrine and Caffeine, Caffeine
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
Preterm, Apnea of Prematurity
Caffeine Citrate Use and Electronic Activity of the Diaphragm (EDI) Changes
Caffeine citrate, the first-line agent for apnea of prematurity, enhances diaphragmatic activity. EDI values of neurally adjusted ventilatory assist (NAVA) modes can be used to quantify the diaphragmatic activity triggered by…
- Conditions
- Preterm, Apnea of Prematurity, Caffeine
- Trial name
- NCT05393817
- Testing
- caffeine citrate
- Where
- South Korea
- Volunteers
- 14 people
- Sponsor
- Seoul St. Mary's Hospital