Clinical trials: Caffeine, completed
Pre-Exposure Prophylaxis
Leveraging Electronic Health Record Data in a Risk Prediction Model to Increase HIV PrEP Intake in Primary Care
Kaiser Permanente Northern California (KPNC) has been a national leader in implementation of HIV preexposure prophylaxis (PrEP), a daily antiretroviral pill that is more than 99% effective in preventing HIV acquisition.
- Trial name
- NCT05991869
- Testing
- Point-of-care decision support intervention
- Where
- United States
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
ADHD, Attention Difficulties
A Clinical Trial to Assess the Efficacy of a Plant-based Energy Shot on Focus and ADHD-like Symptoms
This is a virtual, single-arm clinical trial that will last 28 days. Participants will drink 1 bottle of Proper Wild energy shot daily and complete questionnaires at baseline, day 1, day 14, and day 28.
- Conditions
- ADHD, Attention Difficulties, Mood, Anxiety
- Trial name
- NCT05857956
- Testing
- Proper Wild energy shot
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Proper Wild, Inc.
Irritable Bowel Syndrome
Diets in Symptom Relief and the Influence of Quality of Life in People With Irritable Bowel Syndrome
Subjects with confirmed diagnosis of Irritable Bowel Syndrome will be blinded and randomly assigned to one of two groups, the low FODMAP diet or the conventional IBS diet group.
- Trial name
- NCT02450370
- Testing
- Low FODMAP diet, Conventional IBS diet group
- Where
- Hong Kong
- Volunteers
- 103 people
- Sponsor
- Hong Kong Sanatorium & Hospital
Caffeine, Ischemic Preconditioning
The Effect of Caffeine on Ischemic Preconditioning
Ischaemic preconditioning (IP) describes the phenomenon that brief periods of ischaemia render the (myocardial) muscle more resistant to a subsequent more prolonged period of ischaemia and reperfusion.
- Conditions
- Caffeine, Ischemic Preconditioning, Ischemia-Reperfusion Injury
- Trial name
- NCT00184912
- Testing
- caffeine, Technetium-TC99m-labeled Annexin A5, ten minutes forearm ischemia
- Where
- Netherlands
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Running Performance
Does a Caffeine Gum Improve 5 km Run Performance in a Competition/Field Setting?
The purpose of this study is to determine whether caffeine gum improves the performance of runners completing free timed mass participation 5 km runs in the United Kingdom (UK)
- Trial name
- NCT02473575
- Testing
- caffeine gum
- Where
- United Kingdom
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Sheffield Hallam University
Acute Kidney Injury, Chronic Kidney Diseases
Impact on Mortality of Screening for Kidney Disease Associated With a Specialized Intervention During Hospitalization in a Territorial Hospital Trust
Kidney disease in its chronic or acute form shares many risk factors for initiation, progression and prognosis with an increase in morbidity and mortality, the length of hospitalization and the cost associated with stages of…
- Trial name
- WARNING KD (NCT05033652)
- Testing
- WARNING KD
- Where
- 3 sites in France
- Volunteers
- 1,179 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Caffeine, Placebo
Acute Caffeine Intake in Young vs Older Adults
Evidence regarding the ergogenic effects of caffeine is well-established in young adults, but evidence in older adults remains scarce, particularly during dynamic resistance exercise.
- Trial name
- CAF+Age (NCT07711652)
- Testing
- Caffeine
- Where
- Spain
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Alcala
Stroke
Use of the Thrombectomy Device ReVive™ SE in the Acute Treatment of Stroke
The last marketed thrombectomy devices, named stentretriever, permit a better and faster recanalization in patient with a stroke.
- Trial name
- REVIVE SE (NCT02971826)
- Testing
- REVIVETM SE thrombectomy
- Where
- France
- Volunteers
- 1 people
- Sponsor
- Hospices Civils de Lyon
Body Composition Measurement
Acute Effects of Caffeinated and Decaffeinated Coffee on Bioelectrical Impedance Analysis
This study investigates how caffeinated coffee, decaffeinated coffee, and water affect body composition, as measured by BIA. Participants were divided into three groups, consuming their respective beverages, with measurements…
- Trial name
- NCT06754748
- Testing
- Caffeinated coffee, Decaffeinated coffee, Water
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Marmara University
Postoperative Ileus, Caffeine
Can Coffee/Caffeine Improve Post-Operative Gastrointestinal Recovery
Disruption of the normal gastrointestinal (GI) motility is a well-known consequence of major surgery. The pathophysiology behind this phenomenon is not fully understood but involves the autonomic nervous system as well as a…
- Trial name
- NCT04547868
- Testing
- Coffee, Decaffeinated Coffee, Warm water
- Where
- 3 sites in Canada
- Volunteers
- 174 people
- Sponsor
- Sunnybrook Health Sciences Centre
Delirium
Recommendations and Alerting for Delirium Alleviation in Real-Time (RADAR)
This is a pilot randomized controlled trial that will test whether a multicomponent decision support system will improve the postoperative environment for neurocognitive and clinical recovery in older, high-risk surgical…
- Trial name
- NCT04007523
- Testing
- Family Support System, HELP Support System
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Michigan
Healthy Volunteers
Study of Human Non-Shivering Thermogenesis and Basal Metabolic Rate
Background: Changes in how a person's body burns energy or calories can affect their weight over time. The lowest level of energy the body needs to function is called basal metabolic rate.
- Trial name
- NCT01950520
- Testing
- Propranolol, Pindolol, Dantrolene
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Caffeine-Related Disorders
Validation of a 24-hour Caffeine Intake Recall
A 24-hour Caffeine Intake Recall (CIR-24) was developed to estimate caffeine consumption in the previous 24 hours, modeled after the Automated Self-Administered 24-hour Dietary Assessment Tool (ASA24), using a brand-specific…
- Trial name
- NCT03292380
- Testing
- No intervention was included
- Where
- Canada
- Volunteers
- 79 people
- Sponsor
- University of Waterloo
Operation, Cesarean Section
Effect of Coffee Consumption on Pain and Intestinal Motility After Caesarean Section:
Objective The aim of this study was to investigate whether postoperative coffee intake affects pain levels and bowel motility in women undergoing cesarean delivery.
- Trial name
- NCT06359223
- Testing
- coffee consumption, control group
- Where
- Turkey (Türkiye)
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Premature Atrial Contractions, Premature Ventricular Contractions
Coffee and Real-time Atrial and Ventricular Ectopy
Atrial fibrillation (AF) and heart failure (HF) are morbid, costly, and incompletely understood diseases that have reached epidemic proportions worldwide.
- Trial name
- CRAVE (NCT03671759)
- Testing
- Start: On Caffeine, Start: Off Caffeine
- Where
- United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Analgesia
Management of Post Dural Pucture Headache After Lower Limb Surgeries: Oral Prednisolone vs Oral Pregabalin
The aim of this study is to compare between oral prednisolone and oral pregabalin in management of PDPH to detect effectiveness of the treatment in reducing severity of PDPH, total rescue analgesic consumption and adverse effects…
- Trial name
- NCT04662125
- Testing
- caffeine, paracetamol tablet, Oral prednisolone, oral pregabalin
- Where
- Egypt
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Hypoxic-Ischemic Encephalopathy
Caffeine for Hypoxic-Ischemic Encephalopathy
Hypoxic-ischemic encephalopathy (HIE) due to perinatal asphyxia is common and often fatal. Therapeutic hypothermia reduces mortality and morbidity in infants with HIE.
- Trial name
- NCT03913221
- Testing
- Caffeine Citrate 5 mg/kg, Caffeine Citrate 10 mg/kg
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- University of North Carolina, Chapel Hill
Normal Controls
Herbal Extract Study
The objective of this study is to assess the effects of an herbal extract on mental energy in healthy human subjects.
- Trial name
- NCT02095301
- Testing
- Herbal Beverage
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- PepsiCo Global R&D
Syncope, Vasovagal
The Effect of CPC on Aborting Tilt Induced Syncope in Patients With a History of Vasovagal Syncope or Near Syncope
Syncope is defined as transient loss of consciousness associated with inability to maintain postural tone with rapid and spontaneous recovery.
- Trial name
- NCT04972123
- Testing
- CPC - Capsaicin, Phenylephrine, Caffeine, Tilt Table Test
- Where
- United States
- Volunteers
- 143 people
- Sponsor
- University of Wisconsin, Madison
Absorption, Pharmacokinetic
Clinical Study to Compare the Effect of an Oral Rehydration Solution on the Rate of Absorption of Functional Ingredients
The objective of this study was to compare the individual pharmacokinetics of functional ingredients included in an oral rehydration solution (ORS) with or without the inclusion of active base ingredients (carbohydrate and…
- Trial name
- NCT06524674
- Testing
- Hydration Multiplier + Energy, Hydration Multiplier + Sleep, Energy Comp
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Liquid I.V.