Clinical trials: Celecoxib, completed
Peptic Ulcers
Celebrex Low Dose ASA Study Examining the Incidence of Gastroduodenal Ulcers in a Healthy Population
The aim of the current study is to replicate the COXA-0508-258 study in a multicenter, US setting, using a lower dose of ASA. It is expected that this study will not only confirm the results of the 258 study but show that the…
- Trial name
- NCT00137033
- Testing
- Celecoxib, Naproxen, ASA
- Where
- 23 sites in United States
- Volunteers
- 605 people, healthy volunteers welcome
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Oral Mucositis
Cox-2 Inhibition in Radiation-induced Oral Mucositis
Oral mucositis refers to ulcerative lesions of the oral mucosa that occur due to radiation therapy given for treatment of head and neck cancer.
- Trial name
- NCT00698204
- Testing
- celecoxib
- Where
- 2 sites in United States
- Volunteers
- 43 people
- Sponsor
- UConn Health
Ovulation, Luteal Development
The Effect of a Non-hormonal Cox-2 Inhibitor (Celebrex) on Ovulation
The purpose of this study is to assess the effect that Celebrex (a COX-2 inhibitor and non-steroidal anti-inflammatory drug) has on ovulation.
- Trial name
- NCT01129245
- Testing
- Celebrex
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Colorectal Adenoma
Prevention of Colorectal Sporadic Adenomatous Polyps (PRESAP)
This study is a prospective, randomized, double-blind, placebo-controlled, multi-center trial to compare the efficacy and safety of celecoxib 400mg QD versus placebo in reducing the occurrence of new colorectal adenomas…
- Trial name
- PRESAP (NCT00141193)
- Testing
- Celecoxib
- Where
- 106 sites in United States, Australia and 30 more
- Volunteers
- 1,561 people
- Sponsor
- Pfizer
Healthy
Effectiveness of Two Different Doses of BI 1026706 on the Overall Peak-to-Peak (PtP) N2/P2-component Amplitude of Laser (Somatosensory, Radiant-heat) Evoked Potentials (LEP) in UVB(Ultraviolet)-Irradiated Skin in Healthy Male Volunteers
To investigate the influence of different doses of BI 1026706 on the primary endpoint (PtP-amplitude LEP in UV skin) compared to placebo. The comparison of both doses of BI 1026706 to celecoxib in the UVB treatment.
- Trial name
- NCT02037165
- Testing
- Pregabalin, BI 1026706, Celecoxib
- Where
- Germany
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Cervix Neoplasms
Celebrex - Cervix: Celecoxib in the Treatment of Patients With Locally Advanced Carcinoma of the Cervix
This is a phase I/II study to evaluate the safety and toxicity of celecoxib in combination with standard concurrent cisplatin and radiotherapy in women with locally advanced cervix cancer.
- Trial name
- NCT00152828
- Testing
- Celecoxib
- Where
- Canada
- Volunteers
- 31 people
- Sponsor
- University Health Network, Toronto
Osteoarthritis, Knee, Osteoarthritis, Hip
Study Of "Continuous Use" Of Celecoxib Vs. "Usual or Intermittent Use"
To determine whether "continuous use" of celecoxib over a 6-month period is more efficacious than "usual or intermittent use" in preventing spontaneous osteoarthritis flares of the knee and hip.
- Trial name
- NCT00139776
- Testing
- Celecoxib
- Where
- 124 sites in United States, Belgium and 6 more
- Volunteers
- 875 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Osteoarthritis
Efficacy and Safety of Shinbaro Capsule
The purpose of this study is to evaluate the efficacy and safety of 'Shinbaro Capsule', a new herbal anti-arthritic agent, in patients with osteoarthritis of the knee.
- Trial name
- NCT01535417
- Testing
- Shinbaro Capsule, Celebrex
- Volunteers
- 198 people
- Sponsor
- Green Cross Corporation
Anti-neutrophil Cytoplasmic Antibody-associated Vasculitis
A Study in Healthy Volunteers to Evaluate the Drug-Drug Interaction Potential of CCX168 With Concomitant Medications
The primary objective of this study will be to evaluate the drug-drug interaction potential of CCX168 with concomitant medications, as either a perpetrator or a victim, following oral administration of CCX168 to healthy…
- Trial name
- NCT06004947
- Testing
- CCX168, Midazolam, Celecoxib
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Amgen
Osteoarthritis
52 Week, International, Multi-center, Randomized, Double-blind, Double-dummy, Parallel-group Clinical Trial to Compare Retention on Treatment, Safety, Tolerability & Efficacy of Lumiracoxib 100 mg od, Lumiracoxib 100 mg Bid & Celecoxib 200 mg od in Pts With Primary OA of Hip, Knee, Hand or Spine
This trial will compare the retention on treatment (based on the rate of patients staying on treatment for 1 year) of patients suffering from primary osteoarthritis using two different doses of lumiracoxib (100 mg od or 100 mg…
- Trial name
- NCT00145301
- Testing
- Lumiracoxib
- Where
- Germany
- Volunteers
- 3,036 people
- Sponsor
- Novartis
Pain
An Open-Label Study Of Celecoxib In Patients With Posttraumatic Pain
To investigate efficacy, safety and tolerability of Celecoxib in patients with posttraumatic pain for the duration of 8 days.
- Trial name
- NCT00976716
- Testing
- Celecoxib
- Where
- 11 sites in Japan
- Volunteers
- 80 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Healthy Volunteers
A Pilot Open-Label Crossover Bioavailability Study of Celecoxib in Healthy Volunteers
A pharmacokinetic study in healthy volunteers to determine the relative bioavailability of three formulations of celecoxib to the approved formulation.
- Trial name
- NCT00813241
- Testing
- celecoxib reference formulation, celecoxib test formulation A1, celecoxib test formulation B2
- Where
- Singapore
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Migraine With Aura, Migraine Without Aura
Can DFN-15 Terminate Migraine With Allodynia?
The majority of migraineurs seeking secondary or tertiary medical care develop cutaneous allodynia during the course of migraine, a sensory abnormality mediated by sensitization of central trigeminovascular neurons in the spinal…
- Conditions
- Migraine With Aura, Migraine Without Aura, Allodynia
- Trial name
- NCT03472378
- Testing
- DFN-15
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Hartford Hospital
Relapsed Multiple Myeloma
ATRA, Celecoxib, and Itraconazole as Maintenance
The purpose of this study is to evaluate the safety and tolerability associated with the combination of ATRA/celecoxib/itraconazole as maintenance therapy given after an autologous stem cell transplant in relapsed multiple…
- Trial name
- NCT02401295
- Testing
- ATRA, Celecoxib, Itraconazole
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- University of Iowa
Gastroduodenal Ulcer
Effect of Naproxen, Aspirin, Celecoxib, or Clopidogrel on the Healing of Stomach and Intestinal Ulcers
Gastroduodenal ulcers are extremely common in the community today. Though much has been written and observed concerning how ulcers form, not much has been described in the human model concerning how these ulcers heal.
- Trial name
- Lesions2 (NCT00778193)
- Testing
- Naproxen, Aspirin, Celecoxib
- Where
- United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Research Associates of New York, LLP
Opioid Use, Shoulder Osteoarthritis
Opioid-Free Shoulder Arthroplasty
Purpose of Study: To identify and provide a safe, opioid-free treatment pathway for shoulder arthroplasty with a focus on perioperative pain control and postoperative symptoms from treatment
- Conditions
- Opioid Use, Shoulder Osteoarthritis, Avascular Necrosis, Rotator Cuff Tear
- Trial name
- NCT03540030
- Testing
- Gabapentin, Celecoxib, toradol
- Where
- United States
- Volunteers
- 86 people
- Sponsor
- OrthoCarolina Research Institute, Inc.
Colorectal Cancer
Celecoxib, Capecitabine, and Irinotecan in Treating Patients With Recurrent or Metastatic Colorectal Cancer
RATIONALE: Celecoxib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Drugs used in chemotherapy, such as capecitabine and irinotecan, work in different ways to stop the growth of tumor…
- Trial name
- NCT00258232
- Testing
- capecitabine, celecoxib, irinotecan hydrochloride
- Where
- 3 sites in United States
- Sponsor
- Barbara Ann Karmanos Cancer Institute
Nausea
Nausea in Patients Receiving Hydromorphone vs Oxycodone After Total Hip Replacement Surgery
The study aims to compare the incidence of side effects caused by Oxycodone and Hydromorphone.
- Trial name
- NCT02295124
- Testing
- Oxycodone, Hydromorphone
- Where
- Canada
- Volunteers
- 200 people
- Sponsor
- University Health Network, Toronto
Healthy Volunteers
Study to Assess the Effect of Co-Administration of AZD9833 on the Pharmacokinetics of Midazolam, of Omeprazole, of Celecoxib and of Dabigatran Etexilate in Healthy Postmenopausal Female Volunteers
This study will be a fixed sequence drug-drug interaction study in healthy postmenopausal females, conducted at multiple study sites
- Trial name
- NCT05438303
- Testing
- AZD9833, Midazolam, Omeprazole
- Where
- 2 sites in United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Smoking, Prevention
Celecoxib as a Chemopreventive Agent in Current and Former Smokers
The purpose of this study is: To examine the effect of celecoxib treatment on Ki-67 expression, a marker of cell proliferation, in the bronchial epithelium of current and former smokers.
- Trial name
- NCT00981201
- Testing
- Celecoxib
- Where
- United States
- Volunteers
- 219 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center