Clinical trials: Celecoxib
Brain and Central Nervous System Tumors
Temozolomide, Thalidomide, and Celecoxib Following Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Thalidomide and celecoxib may stop the growth of tumor cells by stopping blood flow to the tumor and may…
- Trial name
- NCT00047294
- Testing
- celecoxib, temozolomide, thalidomide
- Where
- 4 sites in United States
- Sponsor
- Dana-Farber Cancer Institute
Colorectal Cancer
Cetuximab & Celecoxib for Metastatic Colorectal Cancer or Colorectal Cancer That Cannot Be Removed by Surgery
RATIONALE: Monoclonal antibodies, such as cetuximab, can block tumor growth in different ways. Some block the ability of tumor cells to grow and spread.
- Trial name
- NCT00466505
- Testing
- cetuximab, celecoxib, proteomic profiling
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Vanderbilt-Ingram Cancer Center
Surgery, Pain, Postoperative
Comparing Analgesic Regimen Effectiveness and Safety for Surgery (CARES) Trial
This trial is being completed to compare two commonly used options to treat pain after surgery. Participants that undergo gallbladder removal, hernia repair, and breast lump removal will be eligible to enroll.
- Trial name
- CARES (NCT05722002)
- Testing
- NSAID, Opioid, Acetaminophen
- Where
- 8 sites in United States, Canada
- Volunteers
- 900 people
- Sponsor
- University of Michigan
Advanced Hepatocellular Carcinoma, Metastatic Hepatocellular Carcinoma
Celecoxib, Durvalumab and Tremelimumab for the Treatment of Patients With Advanced or Metastatic Liver Cancer
This phase II trial tests how well the combination of celecoxib with durvalaumab and tremellimumab works in treating patients with hepatocellular cancer (liver cancer) that may have spread from where it first started to nearby…
- Conditions
- Advanced Hepatocellular Carcinoma, Metastatic Hepatocellular Carcinoma, Stage III Hepatocellular Carcinoma AJCC v8, Stage IV Hepatocellular Carcinoma AJCC v8
- Trial name
- NCT07174570
- Testing
- Celecoxib, Durvalumab, Tremelimumab
- Where
- 4 sites in United States
- Volunteers
- 39 people
- Sponsor
- Emory University
Healthy Volunteers
Study to Assess the Effect of Co-Administration of AZD9833 on the Pharmacokinetics of Midazolam, of Omeprazole, of Celecoxib and of Dabigatran Etexilate in Healthy Postmenopausal Female Volunteers
This study will be a fixed sequence drug-drug interaction study in healthy postmenopausal females, conducted at multiple study sites
- Trial name
- NCT05438303
- Testing
- AZD9833, Midazolam, Omeprazole
- Where
- 2 sites in United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Pain
Enhanced Recovery After Bilateral Reduction Mammaplasty
This single-center, clinical trial is being conducted to determine whether non-narcotic pain regiments are as effective as narcotic-based regiments in reducing post-operative pain in patients undergoing breast reduction in the…
- Trial name
- NCT04558840
- Testing
- Macromastia
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Breast Cancer
European Celecoxib Trial in Primary Breast Cancer
It has been found that the chemical changes that take place in a patient's body during the development of inflammation may provide an environment which stimulates cancer cells.
- Trial name
- REACT (NCT02429427)
- Testing
- Celecoxib
- Volunteers
- 2,639 people
- Sponsor
- Imperial College London
Electrophysiologic Property of Brain
Impact of Celecoxib on Electrophysiological Property in Brain of Healthy Volunteer
the purposes of this study are to evaluate the acute electrophysiological response in brain cortex to single oral dose of celecoxib (400mg once) in healthy volunteer and the electrophysiological alteration in brain cortex by…
- Trial name
- NCT02711579
- Testing
- Celecoxib
- Where
- South Korea
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Osteoarthritis
Effect Of Celecoxib On Hip Osteoarthritis (OA) Progression
Objectives of the study: Primary: Assess the ability of a continuous treatment of celecoxib 200 mg versus placebo administered once daily (QD) for 24 months in slowing disease progression as assessed radiographically in subjects…
- Trial name
- NCT00163241
- Testing
- celecoxib
- Where
- 130 sites in Canada, France
- Volunteers
- 666 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Pharyngitis
Testing The Effectiveness Of Celecoxib In Patients With Painful Sore Throat
We are proposing a study in which we utilize and augment the sore throat pain model to assess the analgesic effectiveness of celecoxib compared to placebo in patients with painful pharyngitis under randomized, double-blind…
- Trial name
- NCT00402987
- Testing
- Celecoxib
- Where
- United States
- Volunteers
- 269 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Esophageal Cancer
A Study of Irinotecan, Cisplatin and Celebrex in Patients With Metastatic or Unresectable Esophageal Cancer
This study is for patients with cancer of the esophagus. This study uses the drugs irinotecan, cisplatin and celecoxib. Irinotecan (also known as CPT-11) was recently approved by the U.S.
- Trial name
- NCT00183807
- Testing
- irinotecan, cisplatin, celecoxib
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- University of Southern California
Breast Cancer Female, Postoperative Pain
Multimodal Pain Treatment for Breast Cancer Surgery - a Prospective Cohort Study
Breast cancer is one of the most common types of cancer among women worldwide. (1) Breast-conserving surgery or mastectomy is indicated for the majority of patients with this type of cancer.
- Conditions
- Breast Cancer Female, Postoperative Pain, Postoperative Nausea and Vomiting
- Trial name
- NCT04875559
- Testing
- Standardised multimodal pain treatment regimen
- Where
- Denmark
- Volunteers
- 236 people
- Sponsor
- Zealand University Hospital
Non Muscle Invasive Bladder Cancer
Celecoxib for the Treatment of Non-muscle Invasive Bladder Cancer
The treatment of non-muscle invasive bladder cancer (NMIBC) is problematic given the variable natural history of the disease. Although contemporary treatment options are limited, new targets and new approaches are under…
- Trial name
- NCT02343614
- Testing
- Celecoxib
- Volunteers
- 58 people
- Sponsor
- Azienda Ospedaliero-Universitaria Consorziale Policlinico di Bari
Osteoarthritis, Knee, Osteoarthritis, Hip
Study Of "Continuous Use" Of Celecoxib Vs. "Usual or Intermittent Use"
To determine whether "continuous use" of celecoxib over a 6-month period is more efficacious than "usual or intermittent use" in preventing spontaneous osteoarthritis flares of the knee and hip.
- Trial name
- NCT00139776
- Testing
- Celecoxib
- Where
- 124 sites in United States, Belgium and 6 more
- Volunteers
- 875 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
COVID-19 Disease
Back to the Traditional: Anti-COX Drugs Can Improve the Outcome of COVID-19 Patients Admitted to ICU
Retrospective multicenter study to evaluate the data of COVID-19 patients who were admitted to university hospitals in relation to their recent administration or maintenance on non-steroidal anti-inflammatory drugs (NSAID) prior…
- Trial name
- NCT04757792
- Testing
- File inquiry
- Where
- Egypt
- Volunteers
- 475 people
- Sponsor
- Benha University
Lung Cancer
Celecoxib and Docetaxel in Treating Patients With Non-Small Cell Lung Cancer
RATIONALE: Celecoxib may slow the growth of cancer by stopping blood flow to the tumor. Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die.
- Trial name
- NCT00030407
- Testing
- Celecoxib, Docetaxel
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Barbara Ann Karmanos Cancer Institute
Arthritis, Rheumatoid
A Study Of CP-195543 And Celecoxib Dual Therapy In Subjects With Rheumatoid Arthritis
To evaluate the efficacy, safety and tolerability of CP-195543 and celecoxib dual therapy in subjects with rheumatoid arthritis
- Trial name
- NCT00424294
- Testing
- CP-195,543, celecoxib, Methotrexate
- Where
- 39 sites in United States
- Volunteers
- 70 people
- Sponsor
- Pfizer
Breast Cancer
An Examination of Predictors of Indicators of Response to Celecoxib in Women Who Have a Diagnosis of Early Breast Cancer
To assess the quantitative real time PCR results results of oligonucleotide probes for a number of gene transcription products that may be useful as predictors of indicators of response to celecoxib.
- Trial name
- NCT00291122
- Testing
- celecoxib 400 mg BID
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Kansas
Subacute Thyroiditis
Short-term Prednisone to Treat STA Study(SPTSS)
Efficiency and Safety Study of Short-term Prednisone to Treat Moderate and Severe Subacute Thyroiditis The investigators hypothesize that less adverse reactions will be observed, comparing with the guidelines recommend.
- Trial name
- STA (NCT01837433)
- Testing
- Prednisone 1 week, Prednisone 6 weeks
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Xinqiao Hospital of Chongqing
Ankylosing Spondylitis
NSAIDs Added to Anti-TNF Therapy Versus Anti-TNF Therapy Alone on Progression of Structural Damage in Ankylosing Spondylitis
To evaluate the impact of treatment with a non-steroidal anti-inflammatory drug (NSAID) - Celecoxib - when added to anti-tumour necrosis factor (TNF) therapy - Golimumab - as compared to anti-TNF therapy (Golimumab) alone on…
- Trial name
- CONSUL (NCT02758782)
- Testing
- Golimumab, Celecoxib
- Where
- 19 sites in Germany
- Volunteers
- 156 people
- Sponsor
- Charite University, Berlin, Germany