Clinical trials: Cholecalciferol
Healthy
Defining Vitamin D Insufficiency in School Age Children: A Randomized Placebo Controlled Trial of Vitamin D3
The study objective is to characterize the threshold levels of serum 25-hydroxyvitamin D for the definition of vitamin D insufficiency in 8-14 year old African American and Caucasian children.
- Trial name
- Vitamin D RCT (NCT00732758)
- Testing
- Vitamin D3 1000 IU
- Where
- United States
- Volunteers
- 157 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Sickle Cell Disease, Anemia, Sickle Cell
Daily Vitamin D for Sickle-cell Respiratory Complications
This study aims to answer the question whether daily oral vitamin D supplementation can reduce the risk of respiratory or lung complications in children and adolescents with sickle cell disease.
- Conditions
- Sickle Cell Disease, Anemia, Sickle Cell, Anemia, Hemolytic, Congenital, Respiratory Tract Diseases
- Trial name
- ViDAS-2 (NCT04170348)
- Testing
- Daily oral vitamin D3, 3,333 IU, Monthly oral vitamin D3, 100,000 IU
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- Columbia University
Sarcopenia
Improving Rehabilitation In Sarcopenia (IRIS)
This randomized, double-blind, placebo-controlled supplementation trial tested the hypothesis that nutritional supplementation with muscle-target nutritional supplementation concurrent with regular, controlled physical activity…
- Trial name
- IRIS (NCT03120026)
- Testing
- Experimental product
- Where
- 2 sites in Italy
- Volunteers
- 140 people
- Sponsor
- Azienda di Servizi alla Persona di Pavia
Rheumatoid Arthritis (RA)
Vitamin d Level and it's Association With Disease Activity in Egyptian Rheumatoid Arthritis Patients
Vitamin D level and its association with disease activity in Egyptian Rheumatoid arthritis (RA) patients
- Trial name
- Vitamind (NCT05486715)
- Testing
- Vit D
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Mariam Samir Farg
Obesity; Endocrine
Vitamin D and Its Metabolites Quantification in Adipose Tissues of Obese and Non-obese Patients.
Vitamin D (VD) is a pleiotropic hormone, involved in many physiological processes including calcium and phosphorus absorption. The VD metabolism begin to be well-known and involves a hepatic hydroxylation (mediated by enzymes…
- Trial name
- VITADOSE (NCT03008525)
- Testing
- subcutaneous and visceral adipose tissue biopsies, blood samples analysis
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
COVID-19, SARS-CoV 2
Hydroxychloroquine as Post-Exposure Prophylaxis Against COVID-19 Infection
This is a prospective, double-blind, randomized, placebo-controlled study in two distinct cohorts to evaluate the efficacy and safety of hydroxychloroquine in the prevention of COVID-19 infection.
- Trial name
- NCT04372017
- Testing
- Hydroxychloroquine, Vitamin D
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Sanford Health
Female Infertility Due to Diminished Ovarian Reserve, Vitamin D Deficiency
Differences in Ovarian Reserve Markers and Vitamin D Between Infertile Indian, Arabian and Caucasian Population
The aim of this study is to confirm the difference in ovarian reserve markers and serum vitamine D levels between infertile indian, arabian and caucasian population.
- Conditions
- Female Infertility Due to Diminished Ovarian Reserve, Vitamin D Deficiency, Hormone Deficiency, Follicular Cyst of Ovary
- Trial name
- NCT02209168
- Where
- Spain
- Volunteers
- healthy volunteers welcome
- Sponsor
- IVI Madrid
Asthma
Vitamin D Supplementation During Pregnancy for Prevention of Asthma in Childhood
The aim of this study is to prevent asthma symptoms (recurrent wheeze) in childhood by supplementation with high dose vitamin D to the mother during pregnancy.
- Trial name
- ABCvitaminD (NCT00856947)
- Testing
- Cholecalciferol D3
- Where
- 2 sites in Denmark
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Copenhagen Studies on Asthma in Childhood
Adenomatous Polyps
Chemoprevention of Colorectal Adenomas
The purpose of the study is to investigate if long-term treatment with three known drugs (acetylsalicylic acid, 1α 25-dihydroxy cholecalciferol, and calcium carbonate) prevents recurrence of colorectal adenomas.
- Trial name
- NCT00486512
- Testing
- 0.5 mg calcitriol (1a -25-dihydroxycholecalciferol), 75 mg acetylsalicylic acid (ASA) + 1250 mg calcium carbonate (CaCO3), Colonoscopy
- Where
- 39 sites in United States, Russia
- Volunteers
- 350 people
- Sponsor
- Colotech A/S
Ulcerative Colitis (UC), Crohn Disease (CD)
Effect of Isoflavone and Vitamin D Supplementation on Serum Vitamin D Levels, Body Composition, Inflammatory Markers, and Quality of Life in Patients With Inflammatory Bowel Disease
Inflammatory bowel disease (IBD) is a chronic immune-mediated disorder characterized by recurrent intestinal inflammation, impaired nutritional status, and reduced quality of life.
- Trial name
- NCT07656233
- Testing
- Standard medical treatment, Tempeh Isoflavone, Vitamin D (Cholecalciferol )
- Where
- Indonesia
- Volunteers
- 50 people
- Sponsor
- Universitas Indonesia
Osteoporosis
Safety and Efficacy of OSTEOFORM (rhPTH [1-34]) in Increasing Bone Mineral Density in Osteoporosis
OSTEOFORM, containing recombinant (rhPTH [1-34]), enhances bone mineral density and reduces risk for vertebral fracture. This study evaluates the safety and efficacy of OSTEOFORM in the treatment of osteoporosis in…
- Trial name
- NCT00500409
- Testing
- Osteoform, SHELCAL
- Where
- 6 sites in India
- Volunteers
- 82 people
- Sponsor
- Virchow Group
Vitamin D Deficiency, Hemodialysis Patient
Cholecalciferol Supplementation Effect on Parathyroid Hormone in Hemodialysis Patients
Introduction. Vitamin D regulates mineral metabolism. Its deficiency has been associated with diabetes, cancer and increased mortality. 25OH vitamin D (25VD) is stable and suitable for the evaluation of vitamin D sufficiency.
- Trial name
- NCT03648528
- Testing
- cholecalciferol
- Volunteers
- 120 people
- Sponsor
- Cooperativa Asistencia Sindicato Médico Uruguay
Hashimoto Disease, Treatment Levothyroxine
Effect of Treatment for Vitamin D Deficiency on Thyroid Function and Autoimmunity in Hashimoto's Thyroiditis.
The objective of this study is to evaluate the effect of vitamin D supplementation on thyroid autoimmunity, thyroid function, and other metabolic and clinical variables associated with the thyroid axis in patients with…
- Conditions
- Hashimoto Disease, Treatment Levothyroxine, Vitamin D Deficiency
- Trial name
- NCT04778865
- Testing
- Vitamin D-correction, Vitamin D-RDA
- Where
- Chile
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universidad de Valparaiso
Sarcopenia
Exercise and Nutrition for Healthy AgeiNg
The aim of this randomized placebo-controlled 5-arm clinical trial is to evaluate the effect of combined anabolic interventions compared to single or placebo interventions on physical performance in community-dwelling…
- Trial name
- ENHANce (NCT03649698)
- Testing
- Home-based training program, High-quality protein supplement, Omega-3 fatty acid
- Where
- Belgium
- Volunteers
- 180 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Falls
Effectiveness of the Montpellier Falls Clinic in Preventing InjuRiEs
A falls prevention clinic opened in Montpellier (France) in 2015. The objective of the project is to evaluate whether the tailored multifactorial programme delivered in this real practice setting by a geriatrician, a podiatrist…
- Trial name
- EMPIRE (NCT03737487)
- Testing
- Multidisciplinary fall risk and geriatric comprehensive assessment
- Where
- France
- Volunteers
- 160 people
- Sponsor
- University Hospital, Montpellier
Abortion, Spontaneous
Vitamin D and Angiogenic Markers in Odense Child Cohort 1
The Vitamin D and Angiogenic Marker Study 1: Vitamin D and angiogenic markers in early pregnancy. Epidemiology and associations to early-pregnancy miscarriage
- Trial name
- VITAM (NCT02434900)
- Where
- Denmark
- Volunteers
- 2,874 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
COPD, Asthma
LungVITamin D and OmegA-3 Trial (lungVITAL)
The VITamin D and OmegA-3 TriaL (VITAL; NCT 01169259) is an ongoing randomized clinical trial in 25,871 U.S. men and women investigating whether taking daily dietary supplements of vitamin D3 (2000 IU) or omega-3 fatty acids…
- Conditions
- COPD, Asthma, Pulmonary Function, Pneumonia
- Trial name
- lungVITAL (NCT01728571)
- Testing
- Vitamin D3, fish oil
- Where
- United States
- Volunteers
- 25,871 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Epilepsy, Magnesium Deficiency
Magnesium as a Mediator of Bone and Vitamin D Metabolism in Patients on Antiepileptic Drug Therapy
The objective of this study is to determine the role of magnesium on bone and vitamin D metabolism in patients receiving anti-epileptic medications.
- Conditions
- Epilepsy, Magnesium Deficiency, Vitamin D Deficiency
- Trial name
- NCT03471481
- Testing
- No Intervention. Study is Cross Sectional in nature
- Where
- 2 sites in United States
- Volunteers
- 7 people
- Sponsor
- Drexel University
Alopecia, Androgenetic
Role of Vitamin D in Androgenetic Alopecia
Androgenetic alopecia is a common form of diffuse hair loss in both men and women,It primarily affects the top and front of the scalp with different clinical presentations and there are numerous classification systems for grading…
- Trial name
- NCT03154528
- Testing
- serum vitamin D level by ELISA
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Assiut University
Vitamin D Deficiency
Effects of Vitamin D Dose and Genotype of the Binding Protein in Infants and Children
The purpose of this study is to determine if the vitamin D binding protein genotype influences circulating vitamin D levels and if it may have functional consequences on vitamin D activity.
- Trial name
- VitaD (NCT01050387)
- Testing
- Vitamin D
- Where
- United States
- Volunteers
- 193 people, healthy volunteers welcome
- Sponsor
- Yale University
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