Clinical trials: Cholecalciferol
Inflammation; Muscle, Iron Metabolism
The Effect of Supplementation of Vitamin D3 on Inflammation Induced by 100 km Running, Iron Metabolism and Erythropoiesis
A group of runners received vitamin D (10,000 IU - international unit per day) for two weeks. The aim of the intervention was to check the effect of vitamin D supplementation on selected parameters of inflammation and iron…
- Conditions
- Inflammation; Muscle, Iron Metabolism, Ineffective Erythropoiesis, Healthy
- Trial name
- NCT05880030
- Testing
- Cholecalciferol
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Gdansk University of Physical Education and Sport
Covid19, Vitamin D
Efficacy of Vitamin D Treatment in Pediatric Patients Hospitalized by COVID-19
Open controlled clinical trial. Hospitalized pediatric patients with COVID-19 will be included. Upon admission to hospital serum determination of vitamin D, interleukins, ferritin and Dimer D will be performed.
- Conditions
- Covid19, Vitamin D, Children, Only
- Trial name
- COVID-19 (NCT04502667)
- Testing
- Cholecalciferol
- Where
- Mexico
- Volunteers
- 45 people
- Sponsor
- Coordinación de Investigación en Salud, Mexico
Food Allergy
Can Vitamin D Supplementation in the First Year of Life Prevent Food Allergy in Infants? The VITALITY Trial: Parts 1&2
We report that Australia has the highest prevalence of Immunoglobulin(Ig)E-mediated food allergy in the world, with 10% of infants having challenge-proven food allergy in Melbourne.
- Trial name
- VITALITY (NCT02112734)
- Testing
- Vitamin D
- Where
- Australia
- Volunteers
- 2,739 people, healthy volunteers welcome
- Sponsor
- Murdoch Childrens Research Institute
Cutaneous Squamous Cell Carcinoma, Actinic Keratoses
Immunotherapy Before Transplantation for Skin Cancer Prevention in Organ Transplant Recipients
This clinical trial aims to investigate the efficacy of Calcipotriol ointment combined with 5-fluorouracil cream as an immunotherapy for actinic keratosis in Organ Transplant Recipients (OTRs) before transplantation and determine…
- Conditions
- Cutaneous Squamous Cell Carcinoma, Actinic Keratoses, Skin Cancer, Organ Transplant Recipients
- Trial name
- NCT04329221
- Testing
- Calcipotriol Only Product in Cutaneous Dose Form, Vaseline, Topical 5FU
- Where
- 2 sites in United States
- Sponsor
- Massachusetts General Hospital
Hypertensive Disease, Deficiency of Vitamin D3
Effect of Vitamin D3 on Cardiovascular Risk Factors
The aim of this study is to investigate whether a supplementation of Vitamin D3 can be used to reduce atherosclerotic risk factors.
- Trial name
- NCT01501916
- Testing
- Vitamin D3
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Martin-Luther-Universität Halle-Wittenberg
Non-Alcoholic Fatty Liver Disease, Osteoporosis
Effect of Fatty Liver Disease on Bone Density
Non Alcohlic Fatty Liver (NAFLD) is a spectrum of diseases that ranges from accumulation of fat in the liver (Hepatosteatosis) that may be accompanied by inflammation (Steatohepatitis) to necrosis, fibrosis and even cirrhosis…
- Trial name
- NCT04850547
- Volunteers
- 80 people
- Sponsor
- Sohag University
Rheumatic Arthritis
Impact of Vitamin D in Rheumatoid Arthritis
The goal of this prospective, randomized, parallel-group design, double-blind, and 6-month follow-up is to evaluate the impact of 4000 IU/day vitamin D on 25-hydroxyvitamin D [25(OH)D] levels and inflammatory mediators in people…
- Trial name
- NCT06716476
- Testing
- Vitamin D
- Where
- Kosovo
- Volunteers
- 100 people
- Sponsor
- University of Pristina
Chronic Kidney Disease, Vitamin D Deficiency
hCAP18 Levels and Vitamin D Deficiency in Chronic Kidney Disease
The human immune system produces a protein called hCAP18 (also known as LL-37 or cathelicidin). This protein is believed to help the body to fight infections.
- Trial name
- NCT01026363
- Testing
- Ergocalciferol, Calcitriol
- Where
- United States
- Sponsor
- Massachusetts General Hospital
Hypovitaminosis D
Importance of Dosing Regimen for the Effect of Vitamin D Supplementation
Vitamin D is a hormone with effects not only on the skeleton, but on most tissues in the body. Lack of vitamin D is associated with cardio-vascular disease (CVD), type 2 diabetes, cancer, infectious and immunological diseases, as…
- Trial name
- NCT03272126
- Testing
- Vitamin D
- Where
- Norway
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- University of Tromso
Prostate Cancer
Calcitriol and Carboplatin in Treating Patients With Stage IV Prostate Cancer That Has Not Responded to Hormone Therapy
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Calcitriol may help carboplatin kill more cancer cells by making tumor cells more sensitive to the drug.
- Trial name
- NCT00017576
- Testing
- calcitriol, carboplatin
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- OHSU Knight Cancer Institute
Hematopoietic Stem Cell Transplant
A Randomized Trial of Vitamin D Supplementation With or Without Vitamin A in Stem Cell Transplantation
The investigators hypothesize that supplementation with vitamins A and D will reduce the incidence of acute gastrointestinal graft versus host disease (GI GVHD) compared with supplementation with vitamin D alone.
- Trial name
- NCT03202849
- Testing
- Vitamin D and A
- Where
- United States
- Volunteers
- 83 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Chronic Kidney Disease
Vascular Reactivity in Chronic Kidney Disease (CKD) Patients Receiving Paricalcitol Versus Placebo
This research is studying how Vitamin D may affect blood vessels reaction to stress and blood levels of substances that may increase blockages in the blood vessels in chronic kidney disease (CKD) patients.
- Trial name
- NCT00915876
- Testing
- Paricalcitol
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Amy Barton Pai
Vitamin D Deficiency
Vitamin D Intervention Trial in Healthy Chinese, Phase II
This is a double-blind, randomized, placebo-controlled trial. Based on inclusion and exclusion criteria, 400 eligible volunteers, who were 20-45 years, with 25-hydroxyvitamin D between 12.5-50 nmol/L and BMI between 18.5-28…
- Trial name
- NCT01998763
- Testing
- Vitamin D3
- Where
- China
- Volunteers
- 448 people, healthy volunteers welcome
- Sponsor
- Chinese Academy of Sciences
Kidney Disease
Prevention of Secondary Hyperparathyroidism With Vitamin D in Stage II/III Chronic Kidney Disease
This study will evaluate whether earlier intervention with vitamin D in stage II/III chronic kidney disease will prevent or delay secondary hyperparathyroidism.
- Trial name
- POSH-D (NCT00781417)
- Testing
- Vitamin D
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Atlanta VA Medical Center
Chronic Lymphocytic Leukemia, Non-Hodgkin Lymphoma
Cholecalciferol in Newly Diagnosed Non-Hodgkin Lymphoma or Chronic Lymphocytic Leukemia With Vitamin D Deficiency
This randomized pilot early phase I trial studies how well cholecalciferol works in treating patients with newly diagnosed non-Hodgkin lymphoma or chronic lymphocytic leukemia with low levels of vitamin D (vitamin D deficiency).
- Conditions
- Chronic Lymphocytic Leukemia, Non-Hodgkin Lymphoma, Untreated Chronic Lymphocytic Leukemia, Vitamin D Deficiency
- Trial name
- NCT02553447
- Testing
- Cholecalciferol, Laboratory Biomarker Analysis
- Where
- United States
- Volunteers
- 197 people
- Sponsor
- University of Nebraska
Allergic Conjunctivitis
The Role of Vitamin D in Corneal Epithelial Barrier Function, Ocular Microbiome, Ocular Inflammation, and Visual Acuity of Children With Allergic Conjunctivitis
A double-blind study to evaluate the role of vitamin D in corneal epithelial barrier function, ocular microbiome, ocular inflammation, and visual acuity of children with allergic conjunctivitis.
- Trial name
- NCT05839938
- Testing
- Vitamin D
- Where
- Taiwan
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- China Medical University Hospital
Infertility, Infertility, Female
The Effect of Vitamin D on Fertility
Objective: To examine the effect of vitamin D supplements on the pregnancy and clinical pregnancy rate in embryo transfer cycles. Design: Experimental study with a pre- and post-test.
- Conditions
- Infertility, Infertility, Female, Vitamin D Deficiency, Vitamin D3 Deficiency
- Trial name
- NCT03890458
- Testing
- DEVIT-3
- Where
- Turkey (Türkiye)
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Chronic Kidney Disease, Anemia of Chronic Disease
Effects of Vitamin D Replacement on Hormones Regulating Iron Metabolism in Individuals With Chronic Kidney Disease
The purpose of the study is to learn more about how treatment with vitamin D can affect iron metabolism and blood levels of two hormones that control iron levels, hepcidin and hemojuvelin in people with chronic kidney disease…
- Trial name
- NCT01988116
- Testing
- Oral Calcitriol 0.5 mcg once daily for 6 weeks
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Alabama at Birmingham
Cardiovascular Disease
Role of Vitamin D in Secondary Prevention of Cardiovascular Events
The purpose of this study is to determine if Vitamin D supplementation helps prevent recurrent cardiovascular events, such as heart attack or stroke, in patients who have already experienced at least one cardiovascular event.
- Trial name
- NCT01018849
- Testing
- Cholecalciferol
- Where
- 2 sites in United States
- Volunteers
- 24 people
- Sponsor
- Creighton University
HMG COA Reductase Inhibitor Adverse Reaction
Muscle-Related Side Effects of Statins: Functional Impact, Mechanisms, and Potential Relief With Vitamin D Supplementation
This proposal will explore muscle function (strength and endurance) in men and women suffering from statin-induced muscle symptoms. The mechanisms responsible for these muscle symptoms will be explored.
- Trial name
- NCT01493648
- Testing
- Vitamin D
- Where
- Canada
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- CHU de Quebec-Universite Laval
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