Clinical trials: Cholecalciferol
Vitamin D Deficiency, Stem Cell Transplant Complications
A Randomized Phase IV Control Trial of Single High Dose Oral Vitamin D3 in Pediatric Patients Undergoing HSCT
Research has suggested that children with sufficient vitamin D levels undergoing hematopoietic stem cell transplant (HSCT) have improved outcomes, including lower incidences of infection and graft-versus-host disease (GVHD), as…
- Conditions
- Vitamin D Deficiency, Stem Cell Transplant Complications, Pediatric Cancer, Blood Disorder
- Trial name
- NCT03176849
- Testing
- Vitamin D3, Standard Vitamin D3 Supplementation
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- Phoenix Children's Hospital
Memory Disorders, Age-Related Cognitive Decline
Effect of Vitamin D on Cognitive Decline of Patients With Memory Complaint
As recommended allowance of oral vitamine D are unable to ensure the recommended serum concentration of vitamine D, the purpose of this study is to show that a dose of vitamin D3 higher than the recommended allowance may slow the…
- Trial name
- D-COG (NCT02185222)
- Testing
- Cholecalciferol 100 000 UI
- Where
- 11 sites in France
- Volunteers
- 68 people
- Sponsor
- University Hospital, Tours
Insulin Resistance
Effect of Vitamin D Repletion on Insulin Resistance and Systemic Inflammation
The purpose of this research is to study the effects of Vitamin D supplementation on the body's response to insulin (a hormone that controls blood sugar), on inflammation, and on specific cells and processes in fat tissue.
- Trial name
- NCT01354964
- Testing
- Vitamin D
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Albert Einstein College of Medicine
Ergocalciferol
Pilot Study: The Effect of Ergocalciferol on Plasma Mucin-1 Levels
To determine if a one-time oral administration of ergocalciferol results in a decline in plasma mucin-1 levels in healthy individuals and individuals with ADTKD-MUC1.
- Trial name
- NCT03747523
- Testing
- Ergocalciferol
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Deficiency, Vitamin D
Vitamin D Supplementation During Lactation
This randomized, placebo-controlled trial in Thai pregnancy is conducted. The study aims to determine whether vitamin D3 1,800 IU/d supplementation in lactating mother improves vitamin D status of breastfed infant.
- Trial name
- NCT02297568
- Testing
- Calciferol
- Where
- Thailand
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Department of Medical Services Ministry of Public Health of Thailand
Diabetes, Executive Dysfunction
Can Vitamin D3 Improve Cognitive Function in Individuals With Type 2 Diabetes? (THINK-D)
Diabetes increases the risk of cognitive dysfunction. The incidence of dementia is 1.5 to 2.5 times higher in persons with diabetes than the general population.
- Trial name
- THINK-D (NCT02416193)
- Testing
- Cholecalciferol
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Loyola University
Colon Cancer, Rectal Cancer
Effectiveness of High Dose Vitamin D Supplementation in Stage III Colorectal Cancer
This is a pilot study to test whether there is an association between baseline Vitamin D levels, Vitamin D supplementation and survival in patients with stage III colon and stage II/III rectal cancer receiving chemotherapy.
- Trial name
- NCT02603757
- Testing
- cholecalciferol
- Where
- 3 sites in United States
- Volunteers
- 70 people
- Sponsor
- Legacy Health System
Peripheral Arterial Disease
Pilot Study of Vitamin D Screening Use in Peripheral Arterial Disease Patient Over Maximum Distance Walking
The prevalence of peripheral arterial disease (PAD) is greater than 15%. PAD is associated with an increased risk of cardiovascular death, coronary heart disease and stroke, with a mortality rate of 5% per year.
- Trial name
- First-BLINDOS (NCT03615833)
- Testing
- Cholecalciferol
- Where
- France
- Volunteers
- 27 people
- Sponsor
- University Hospital, Angers
Crohn's Disease
The Vitamin D in Pediatric Crohn's Disease
The purpose of this study is to determine if vitamin D as an adjuvant therapy can improve the outcome (i.e. fewer relapses) and the quality of life, including levels of physical activity, in children with newly diagnosed Crohn's…
- Trial name
- ViDiPeC (NCT02186275)
- Testing
- Vitamin D3: 3000 or 4000 UI/day then 2,000 UI/day, Vitamin D3 800 UI/day then 800 UI/day
- Where
- 10 sites in Canada
- Volunteers
- 25 people
- Sponsor
- St. Justine's Hospital
COVID-19
Effect of Vitamin D on Morbidity and Mortality of the COVID-19
Patients diagnosed of COVID-19 disease are randomized to receive a single dose of 100.000 IU of Cholecalciferol (Vitamin D arm) or no vitamin D (on top of the current medication used to treat COVID 19).
- Trial name
- COVID-VIT-D (NCT04552951)
- Testing
- Cholecalciferol
- Where
- Spain
- Volunteers
- 80 people
- Sponsor
- Fundación para la Investigación Biosanitaria del Principado de Asturias
Vitamin D Deficiency
'Palliative-D' Vitamin D to Palliative Cancer Patients
To test the hypothesis that vitamin D treatment during 12 weeks to palliative cancer patients can decrease opioid consumption, fatigue and infectious burden and increase quality of life.
- Trial name
- Palliative-D (NCT03038516)
- Testing
- Cholecalciferol
- Where
- 3 sites in Sweden
- Volunteers
- 244 people
- Sponsor
- Region Stockholm
COVID19
International ALLIANCE Study of Therapies to Prevent Progression of COVID-19
COVID-19 is a global pandemic. So far encouraging results have been shown in different parts of the world with the utilisation of hydroxycloroquine, zinc, and azithromycin, and early studies into some of these, plus some with…
- Trial name
- NCT04395768
- Testing
- Vitamin C, Hydroxychloroquine, Azithromycin
- Where
- Australia
- Volunteers
- 200 people
- Sponsor
- National Institute of Integrative Medicine, Australia
Critically Ill
The Association of Vitamin D Supplementation With the Outcome in Critically Ill Children
Vitamin D deficiency is highly prevalent in critically ill adult and pediatric population that causes multiple adverse health outcomes including higher illness severity score, increased morbidity and mortality, multiple organ…
- Trial name
- NCT04536831
- Testing
- Vitamin D, Normal saline
- Where
- Pakistan
- Volunteers
- 96 people
- Sponsor
- Dr Mustahsin Khalil
Skeletal Disorder
Bone and Muscle Health in Kids
Vitamin D deficiency in childhood leads to poor bone growth and muscle weakness, yet it is unknown if the amount of vitamin D a woman consumes during her pregnancy affects her child's bone and muscle development.
- Trial name
- BONUSKids (NCT03537443)
- Testing
- Cholecalciferol (vitamin D3)
- Where
- Bangladesh
- Volunteers
- 642 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children
Vitamin D Deficiency
High Dose Vitamin D Replacement in Patients Undergoing Hematopoietic Stem Cell Transplantation
The purpose of this study is to test the efficacy and safety of high dose vitamin D therapy among HSCT patients in a tiered, step-wise manner (step one/two) in order to define treatment doses capable of providing vitamin D…
- Trial name
- NCT02876822
- Testing
- Vitamin D
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Childhood Obesity
Effect of POSTbiotics Supplementation on Microbiome in OBese Children: the POST-OB Study
This study evaluates the possible effect of postbiotics supplementation, combined with interventions aimed at improving diet and lifestyle, on gut microbiota composition and metabolite production.
- Trial name
- POST-OB (NCT04151823)
- Testing
- Vitamin D3, Immunofos, Promotion of physical activity
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- University of Milan
Pulmonary Disease, Chronic Obstructive
Cathelicidin and Vitamin D: Impact on Populations At-Risk and With COPD
This proposal will evaluate a potential mechanism of increased risk of lung function impairment, cathelicidin levels, as well as determine if vitamin D replacement can alter this pathway.
- Trial name
- NCT02464059
- Testing
- Vitamin D3
- Where
- 2 sites in United States
- Volunteers
- 23 people
- Sponsor
- University of North Carolina, Chapel Hill
Chronic Lymphoid Leukemia
The Effect of 25-OH-Vitamin-D3 Substitution in Patients With Malignant and Immune-hematologic Diseases
Recent data have shown that the inadequate vitamin D status plays a role in the manifestation of the haematologic tumors and serum vitamin D level has a prognostic role also as it determines the tumor mortality.
- Trial name
- D-HEM (NCT01518959)
- Testing
- Cholecalciferol, oleum neutralicum
- Where
- Hungary
- Volunteers
- 31 people
- Sponsor
- Semmelweis University
Latent Tuberculosis
Vitamin D Supplementation in TB Prevention
The goal of this clinical trial is to determine whether vitamin D supplementation reduces risk of acquiring latent tuberculosis infection (LTBI) in school age children in Mongolia.
- Trial name
- NCT02276755
- Testing
- Cholecalciferol (vitamin D3)
- Where
- Mongolia
- Volunteers
- 8,851 people, healthy volunteers welcome
- Sponsor
- Harvard School of Public Health (HSPH)
Vitamin D Deficiency
Effect of Vitamin d and Omega 3 on Osteocalcin
Assessing the combined effect of omega-3 fatty acid and vitamin D 3 on plasma osteocalcin levels
- Trial name
- NCT04005612
- Testing
- vitamin D3, omega-3 fatty acid, vitamin D3 and omega-3 fatty acid
- Where
- Jordan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Applied Science Private University