Clinical trials: Cholecalciferol
Colorectal Cancer
DNA Changes That Affect Vitamin D Metabolism in Patients With Colorectal Cancer Receiving Vitamin D Supplements
RATIONALE: Studying samples of blood from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer.
- Trial name
- NCT00550563
- Testing
- cholecalciferol, polymerase chain reaction, polymorphism analysis
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Roswell Park Cancer Institute
Chronic Kidney Disease Stage 3 and 4
Vitamin D Supplement Study for Stage Three and Four Chronic Kidney Disease (CKD) Patients
The purpose of this study is to examine the effectiveness of vitamin D3 versus vitamin D2 in raising vitamin D levels and suppressing parathyroid hormone levels in patients with kidney disease who are not on dialysis.
- Trial name
- UPGRADE (NCT01173848)
- Testing
- Ergocalciferol, Cholecalciferol
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- The Cleveland Clinic
Vitamin D Deficiency
The Effect Of Vitamin D On Measures Of Bone Health And Gene Expression
Vitamin D deficiency is now recognized as one of the most common vitamin deficiencies in adults in the United States. Vitamin D deficiency has been connected to many chronic health diseases.
- Trial name
- NCT01696409
- Testing
- 400 IU vitamin D3, 2000 IU vitamin D3
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Boston University
Dyslipidemias
Effect of Vitamin D Supplementation on Exercise Adaptations in Patients on Statin Therapy
Statins along with lifestyle modifications including exercise are commonly prescribed to patients with type 2 diabetes. American diabetes association recommends using moderate-intensity statin and lifestyle therapy for patients…
- Trial name
- NCT02030041
- Testing
- Vitamin D, Simvastatin
- Where
- India
- Volunteers
- 33 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Obesity, Vitamin D Deficiency
Vitamin D Supplementation Reduces Renin-Angiotensin System Activity in Obesity
Hypothesis: Vitamin D supplementation lower renin-angiotensin system activity in obesity. Specific Aim: To investigate whether Vitamin D supplementation in obesity improves the vascular sensitivity to angiotensin II.
- Conditions
- Obesity, Vitamin D Deficiency, Hypertension
- Trial name
- NCT01068418
- Testing
- Vitamin D (cholecalciferol)
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Brigham and Women's Hospital
Hypovitaminosis D
Vitamin D Status in Lower Extremity Joint Replacement Surgery Patients
In the United States, ~1 million elective hip or knee replacement surgeries are performed annually. With estimated surgical site infection (SSI) rates as high as 2.5%, this represents ~25,000 patients at risk of potentially…
- Trial name
- NCT01858051
- Testing
- Cholecalciferol
- Where
- United States
- Sponsor
- Massachusetts General Hospital
Vitamin D Deficiency
Availability of Vitamin D in Orange Juice
The purpose of this study was to determine whether vitamin D2 and vitamin D3 in orange juice are effective at raising vitamin D levels in the blood and if vitamin D2 and vitamin D3 in orange juice raised blood levels of 25(OH)D…
- Trial name
- NCT01778114
- Testing
- Vitamin D2 in orange juice, Vitamin D3 in orange juice, Vitamin D2
- Where
- United States
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Boston University
Vitamin D Deficiency
Evaluating Vitamin D Content in Mushrooms
This study will evaluate how much vitamin D is present in a mushroom supplement. This supplement contains an extract from mushrooms that have been exposed to sunlight.
- Trial name
- NCT01815437
- Testing
- Mushroom Vitamin D2, Cholecalciferol, Vitamin D2 - Ergocalciferol
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Boston University
Vitamin D Deficiency, Vascular Calcification
Effects of Cholecalciferol on Osteoprotegerin Levels in Patients on Peritoneal Dialysis
Aim: To investigate whether cholecalciferol (4800 U/daily) or placebo for 16 weeks reduces proteins levels associated with vascular calcification (osteoprotegerin, osteopontin, osteocalcin) in patients treated with peritoneal…
- Conditions
- Vitamin D Deficiency, Vascular Calcification, Renal Insufficiency, End Stage Renal Failure on Dialysis
- Trial name
- NCT02598635
- Testing
- Cholecalciferol
- Where
- Mexico
- Volunteers
- 58 people
- Sponsor
- Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
Asthma
Vitamin D and Severe Asthma Exacerbations
This study of vitamin D is designed to assess both the safety and efficacy of potential doses (2,000 IU/day and 4,000 IU/day) in raising a vitamin D level to a normal range in a short period of time (e.g.
- Trial name
- SAVED-P (NCT01921894)
- Testing
- Cholecalciferol
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- University of Pittsburgh
Inflammatory Bowel Disease, Crohn's Disease
Vitamin D Levels in Children With IBD
Research has shown that children with Inflammatory Bowel Disease may have lower levels of vitamin D than healthy children, especially in the winter.
- Conditions
- Inflammatory Bowel Disease, Crohn's Disease, Ulcerative Colitis
- Trial name
- NCT00621257
- Testing
- ergocalciferol, Cholecalciferol
- Where
- United States
- Volunteers
- 134 people
- Sponsor
- Boston Children's Hospital
Gastric Bypass, Parathyroid Hormone
Trial Of Paricalcitol and Cholecalciferol(Vitamin D3) in the Treatment Of Secondary Hyperparathyroidism in Patients After ROUX-EN-Y Gastric Bypass Surgery
Evaluate the efficacy of paricalcitol, cholecalciferol, and placebo in the reduction of parathyroid hormone in patients after Roux-en-Y gastric bypass surgery (RYGB).
- Trial name
- ExtenD (NCT01138475)
- Testing
- Paricalcitol, Cholecalciferol
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Kerstyn C. Zalesin, M.D.
Acute Bronchitis, Upper Respiratory Tract Infection
Effect of Supplementation With Vitamin D on the Acute Bronchitis Prevention During the First Year of Life
A phase III multicenter randomized double blind clinical trial will be conducted. After obtaining written consent the infant will be randomized, during the first two weeks of life, to a study group to receive either 400 IU or…
- Conditions
- Acute Bronchitis, Upper Respiratory Tract Infection, Acute Bronchiolitis
- Trial name
- VitDBR2012 (NCT01875757)
- Testing
- Vitamin D3
- Where
- Spain
- Volunteers
- 200 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
HIV-infection/Aids
Vitamin D Supplementation in HIV
The purpose of this study is to evaluate safety and efficacy of vitamin D supplementation in children, adolescents and young adults with Human Immunodeficiency Virus and acquired immunodeficiency syndrome (HIV/AIDS).
- Trial name
- NCT01475890
- Testing
- Vitamin D3
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- Children's Hospital of Philadelphia
Colorectal Cancer, Polyps
Vitamin D/Calcium Polyp Prevention Study
Extensive experimental and observational data suggest that intake of calcium and of vitamin D exert protective effects on colorectal neoplasia.
- Conditions
- Colorectal Cancer, Polyps, Adenomas
- Trial name
- NCT00153816
- Testing
- Calcium Carbonate, Vitamin D3
- Where
- 11 sites in United States, Puerto Rico
- Volunteers
- 2,813 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Leukemia, Lymphoma
Zoledronic Acid in Preventing Osteoporosis in Patients Undergoing Donor Stem Cell Transplant
RATIONALE: Zoledronic acid, vitamin D, and calcium may prevent bone loss in patients who are undergoing donor stem cell transplant.
- Conditions
- Leukemia, Lymphoma, Myelodysplastic Syndromes, Osteoporosis
- Trial name
- NCT00321932
- Testing
- calcium, cholecalciferol, zoledronic acid
- Where
- 2 sites in United States
- Volunteers
- 61 people
- Sponsor
- University of Minnesota
Hypertension, Vitamin D Deficiency
DAYLIGHT: Vitamin D Therapy in Individuals at High Risk of Hypertension
This is a randomized, double-blind, multicenter, 6-month follow-up trial of low (400 IU/day) versus high (4000 IU/day) dose vitamin D supplementation in individuals with pre- and early stage 1 hypertension and vitamin D…
- Conditions
- Hypertension, Vitamin D Deficiency, Pre-Hypertension
- Trial name
- DAYLIGHT (NCT01240512)
- Testing
- Cholecalciferol
- Where
- 3 sites in United States
- Volunteers
- 534 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Spinal Cord Injury, Vitamin D Deficiency
Vitamin D Deficiency and Replacement on Pulmonary and Endocrine Function in SCI
Studies have shown that individuals who have suffered a spinal cord injury are at an increased risk of Vitamin D deficiency compared to able-bodied individuals.
- Trial name
- NCT02099955
- Testing
- Vitamin D3
- Where
- United States
- Volunteers
- 88 people
- Sponsor
- James J. Peters Veterans Affairs Medical Center
Osteoporosis, Steroid Induced
Effects of Genistein Aglycone in Glucocorticoid Induced Osteoporosis
Prolonged glucocorticoid therapy affects bone fragility, cardiovascular health, glucidic and lipidic metabolism, thyroid and brain function.
- Trial name
- NCT03040531
- Testing
- Genistein aglycone, Alendronate Oral Tablet, Calcium + vitamin D3 tablet
- Where
- 2 sites in Italy
- Volunteers
- 200 people
- Sponsor
- University of Messina
Chronic Obstructive Pulmonary Disease, Muscle Weakness
Cholecalciferol Supplementation in Strengthening Inspiratory Muscles in Cholecalciferol-Deficient Patients With Chronic Obstructive Pulmonary Disease
This phase IIb randomized trial studies how well cholecalciferol (vitamin D3) supplementation works in strengthening inspiratory muscles in cholecalciferol-deficient patients with chronic obstructive pulmonary disease (COPD).
- Trial name
- NCT02877641
- Testing
- Cholecalciferol, Laboratory Biomarker Analysis, Multivitamin
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Roswell Park Cancer Institute