Clinical trials: Clarithromycin
H.Pylori Infection
Safety and Efficacy of Triple and Quadruple Regimens as First Line Therapy for Management of Helicobacter Pylori Infection in Egyptians
Our study aimed to investigate the efficacy and safety of hybrid regimen as a first line therapy for H. pylori eradication compared to triple and quadruple regimens in attempt to overcome antibiotic resistance
- Trial name
- NCT06315478
- Testing
- Omeprazole 20 MG Oral Tablet, Amoxicillin 500Mg Tab, Clarithromycin 500Mg Tab
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Helwan University
Helicobacter Pylori Infection
Helicobacter Pylori Eradication Study
The purpose of this study was to evaluate the efficacy and compliance of tailored therapy which using the polymerase chain reaction for point mutation of clarithromycin, compared to concomitant therapy, in patients without…
- Trial name
- NCT03130452
- Testing
- Lansoprazole 30mg, Amoxicillin 1.0g Tab, Clarithromycin 500mg
- Where
- South Korea
- Volunteers
- 423 people
- Sponsor
- Inje University
H Pylori Infection
Genotypic Resistance Guided Therapy for Refractory H. Pylori Infection
The inviestigators aimed to compare the efficacy of genotypic resistance guided versus susceptibility testing guided therapy in the third line treatment for refractory H. pylori infection.
- Trial name
- NCT03555526
- Testing
- Esomeprazole 40mg, Amoxicillin, metronidazole
- Where
- Taiwan
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Preterm Premature Rupture of Membrane, Pregnancy, High Risk
Improvement of PPROM Management With Prophylactic Antimicrobial Therapy (iPROMPT)
To conduct an unblinded pragmatic randomized controlled trial (pRCT) "Improvement of PPROM Management with Prophylactic Antimicrobial Therapy (iPROMPT)" of a seven-day course of ceftriaxone, clarithromycin, and metronidazole…
- Conditions
- Preterm Premature Rupture of Membrane, Pregnancy, High Risk, Preterm Birth
- Trial name
- NCT06396078
- Testing
- Ceftriaxone 1000 MG, Clarithromycin 500mg, Metronidazole 500 mg
- Where
- 2 sites in United States
- Volunteers
- 56 people
- Sponsor
- Ohio State University
Anemia, Iron-Deficiency, Helicobacter Pylori
Helicobacter Pylori and Iron Deficiency: Prevalence of Association and Effect of Therapy
Iron deficiency anemia (IDA) is a major health problem in children, effecting up to 20% of young children. Helicobacter pylori (HP) infection is also reported to be prevalent in children.
- Trial name
- NCT00475527
- Testing
- omeprazole,clarithromycin,amoxicillin (or metronidazole)
- Where
- Israel
- Sponsor
- Hadassah Medical Organization
Multiple Myeloma
Selinexor and Backbone Treatments of Multiple Myeloma Patients
This study will independently assess the efficacy and safety of 11 combination therapies in 12 arms, in dose-escalation/-evaluation and expansion phases, for the treatment of patients with relapsed/refractory multiple myeloma…
- Trial name
- STOMP (NCT02343042)
- Testing
- Selinexor, Dexamethasone, Lenalidomide
- Where
- 25 sites in United States, Canada
- Volunteers
- 300 people
- Sponsor
- Karyopharm Therapeutics Inc
Gastric Cancer
The Efficacy of Serum Pepsinogen for Prediction of Metachronous Gastric Neoplasm
After endoscopic resection of early gastric cancer (EGC), there remained concerned about the development of the metachronous gastric neoplasm (MGN). The aim of this study was to evaluate the role of H.
- Trial name
- NCT02682446
- Testing
- H pylori eradication
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Kyungpook National University Hospital
Healthy Volunteers, Bioequivalence Study
Bioequivalence Study of Klaribact (Clarithromycin) 500 mg, Film Coated Tablet
This is An Open Label, Randomized, Single Dose, Two Way Cross over, Two Period, Two Treatment, Two Sequence Bioequivalence Study to compare the rate and extent of absorption of Klaribact FC Tablet (Clarithromycin 500 mg) with…
- Trial name
- BE (NCT05436769)
- Testing
- Klaribact 500 mg Clarithromycin Tablet, Klaricid 500 mg Clarithromycin Tablet
- Where
- Pakistan
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Karachi
Cachexia, Lung Cancer
Is Clarithromycin a Potential Treatment for Cachexia in People With Lung Cancer?
This study aims to identify if clarithromycin (CLM) has potential as a widely available and inexpensive treatment for cachexia (the loss of muscle mass) in people with non-small cell lung cancer (NSCLC).
- Trial name
- NCT02416570
- Testing
- Clarithromycin
- Volunteers
- 1 people
- Sponsor
- University of Nottingham
Buruli Ulcer
Beta-Lactam Containing Regimen for the Shortening of Buruli Ulcer Disease Therapy
Buruli ulcer (BU) is a skin Neglected Tropical Disease (NTD) that is caused by Mycobacterium ulcerans. It affects skin, soft tissues and bones causing long-term morbidity, stigma and disability.
- Trial name
- BLMs4BU (NCT05169554)
- Testing
- Standard [RC8]: rifampicin plus clarithromycin (RC) therapy for 8 weeks., Investigational [RCA4]: standard (RC) plus amoxicillin/clavulanate (A) for 4 weeks.
- Where
- 3 sites in Benin
- Volunteers
- 140 people
- Sponsor
- Fundacion Agencia Aragonesa para la Investigacion y Desarrollo (ARAID)
Helicobacter Pylori Infection, Antibiotic Resistant Infection
Non-invasive Test-guided Tailored Therapy Versus Empiric Treatment for Helicobacter Pylori Infection.
The aim of our study will be to assess in an open-label, multicenter, randomized controlled trial whether a tailored therapy guided by a non-invasive antibiotic susceptibility test on stool samples achieves higher Helicobacter…
- Conditions
- Helicobacter Pylori Infection, Antibiotic Resistant Infection, Antibiotic Resistant Strain
- Trial name
- THD-HP (NCT04107194)
- Testing
- Pantoprazole 40mg, Amoxicillin 1000 MG, Clarithromycin 500mg
- Where
- Italy
- Volunteers
- 362 people
- Sponsor
- University of Bari
HELICOBACTER PYLORI INFECTIONS
Efficacy and Safety of Linarazen Gluconate Capsules Combined With Amoxicillin (Dual-Drug Therapy) Versus Bismuth-Containing Quadruple Therapy for First-Line Eradication of Helicobacter Pylori Infection
This clinical trial aims to compare the efficacy of the dual therapy regimen of linralase glutarate capsules and amoxicillin versus the quadruple therapy regimen containing bismuth for the first-line eradication of Helicobacter…
- Trial name
- NCT07897994
- Testing
- Linalarose Glutarate, Bismuth Quadruple Test
- Where
- 24 sites in China
- Volunteers
- 448 people
- Sponsor
- Yongquan Shi
H. Pylori Eradication Failure
Mixed Strain H. Pylori Infection in Patients Who Have Problems With Eradication of H. Pylori
The purpose of this study is to determine whether mixed H. pylori strain infection is the reason for eradication failure during treatment of H. pylori infection.
- Trial name
- NCT01164969
- Testing
- Antibiotics to which H. pylori can not develope resistance
- Where
- Slovenia
- Volunteers
- 10 people
- Sponsor
- University Medical Centre Ljubljana
Acute Bacterial Exacerbation of Chronic Bronchitis (ABECB).
Comparative Study of 5 Days of M02-472 Clarithromycin Extended-Release Tablets to 7 Days of Clarithromycin Immediate-Release Tablets for the Treatment of Exacerbation of Chronic Bronchitis
To compare the efficacy of a 5-day course of clarithromycin extended-release tablets (2 x 500 mg QD) with that of a 7-day course of clarithromycin immediate-release tablets (1 x 500 mg BID) in the treatment of acute bacterial…
- Trial name
- NCT00645086
- Testing
- clarithromycin extended-release tablets, clarithromycin immediate-release tablets
- Where
- 146 sites in United States, Canada and 1 more
- Volunteers
- 465 people
- Sponsor
- Abbott
Peptic Ulcer
The Pilot Study on Tailored Eradication Therapy According to Clarithromycin Resistance in H.Pylori Patients
This study assessed the effect of tailored eradication therapy according to Clarithromycin resistance in Helicobacter pylori patients.
- Trial name
- NCT02648659
- Testing
- Ilaprazole, Amoxicillin, Clarithromycin
- Volunteers
- 50 people
- Sponsor
- Kyungpook National University Hospital
Healthy Volunteers
Evaluate Effects of Multiple Doses of Rifampin and Clarithromycin on the Single Dose Pharmacokinetics of Deflazacort
The primary objective of the study is to determine the potential effects of multiple doses of rifampin and clarithromycin on the single dose pharmacokinetics (PK) of the deflazacort active metabolite (21 desacetyl-DFZ) in healthy…
- Trial name
- NCT02286635
- Testing
- Deflazacort and rifampin, Deflazacort and Clarithromycin
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- PTC Therapeutics
Helicobacter Pylori Eradication Antibiotic
Efficacy and Safety of Ilaprazole Based Bismuth-containing Quadruple Regimen for the First-line Treatment of Helicobacter Pylori Infection
This study compared efficacy and safety of Ilaprazole based bismuth-containing quadruple regimen therapy including Ilaprazole 5mg, Bismuth Potassium Citrate 220mg, Clarithromycin 500mg and Amoxicillin Cap (Amoxicillin) 1000mg BID…
- Trial name
- NCT02835560
- Testing
- Ilaprazole antisecretory drug of each quadruple therapy the Ilaprazole -based quadruple therapy, Esoprazole antisecretory drug of each quadruple therapy Esoprazole-based quadruple therapy
- Volunteers
- 100 people
- Sponsor
- Livzon Pharmaceutical Group Inc.
Multiple Myeloma
Study of Decadron, Biaxin, and Pomalidomide in Relapsed/Refractory Myeloma
This study is intended to investigate the combination of the combination of dexamethasone (Decadron®), Clarithromycin (Biaxin®), and pomalidomide (CC-4047®) [ClaPd] in multiple myeloma patients who have relapsed or refractory…
- Trial name
- NCT01159574
- Testing
- dexamethasone, clarithromycin, Pomalidomide
- Where
- United States
- Volunteers
- 121 people
- Sponsor
- Weill Medical College of Cornell University
Multiple Myeloma
Study of BiRd Regimen Combined With BCMA CAR T-cell Therapy in Newly Diagnosed Multiple Myeloma (MM) Patients
The purpose of this study is to evaluate the safety and efficacy of BiRd regimen combined with BCMA CAR T cell therapy in newly diagnosed multiple myeloma patients
- Trial name
- NCT04287660
- Testing
- clarithromycin, lenalidomide, dexamethasone and autologous BCMA-directed CAR T-cells
- Where
- China
- Volunteers
- 20 people
- Sponsor
- The First Affiliated Hospital of Soochow University
Helicobacter Pylori Infection
Clarithromycin Triple Therapy Plus Bismuth for Helicobacter Pylori First-line Treatment
Standard triple therapy including a proton pump inhibitor (PPI) and clarithromycin with either amoxicillin or metronidazole are no longer recommended as empirical first-line therapy to treat Helicobacter pylori infection because…
- Trial name
- NCT02732249
- Testing
- Esomeprazole, Bismuth Potassium Citrate, Clarithromycin
- Where
- China
- Volunteers
- 66 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine