Clinical trials: Clopidogrel, completed
Coronary Artery Disease
The EFFect of hIgh Dose ClopIdogrel treatmENT in Patients With Clopidogrel Resistance
Continuing high dose clopidogrel treatment after elective PCI decreased adverse cardiac events in patients with clopidogrel resistance
- Trial name
- EFFICIENT (NCT01032668)
- Testing
- Clopidogrel
- Where
- Turkey (Türkiye)
- Volunteers
- 192 people
- Sponsor
- Bursa Postgraduate Hospital
Myocardial Infarction
Adjunctive Cilostazol Versus High Maintenance-dose ClopidogrEL in Acute Myocardial Infarction (AMI) Patients According to CYP2C19 Polymorphism
Percutaneous coronary intervention (PCI) with stent implantation is the preferred reperfusion strategy for treatment of acute myocardial infarction (AMI).
- Trial name
- ACCELAMI2C19 (NCT00915733)
- Testing
- cilostazol, clopidogrel (Plavix), CYP2C19
- Where
- South Korea
- Volunteers
- 80 people
- Sponsor
- Gyeongsang National University Hospital
Ischemic Heart Disease, Acute Coronary Syndromes
Effects of Optimized Antiplatelet Treatment After Percutaneous Coronary Intervention
Effects of dual antiplatelet therapy with aspirin and clopidogrel after percutaneous coronary intervention has been proven. However, patients with low response to those agents are reported be associated with adverse clinical…
- Trial name
- NCT00404781
- Testing
- cilostazol in addition to aspirin and clopidogrel
- Where
- China
- Volunteers
- 305 people
- Sponsor
- Shenyang Northern Hospital
Thrombosis
CASTLE (Clopidogrel And Serum Troponin Level Elevation)
Primary Objective: To test if 600 mg of clopidogrel loading dose administered ≥ 6 and ≤ 24 hours prior to PCI produce a greater decrease of periprocedural release of biochemical markers (CK, CK-MB, and troponin-T and/or I) of…
- Trial name
- CASTLE (NCT00716924)
- Testing
- Clopidogrel
- Where
- Mexico
- Volunteers
- 155 people
- Sponsor
- Sanofi
Antiplatelet Effect
Bleeding Time Study With AZD6482, Clopidogrel and ASA
The primary purpose of this study is to evaluate the effect of AZD6482 and clopidogrel on bleeding time when taken together with low-dose ASA.
- Trial name
- NCT00853450
- Testing
- AZD6482, Clopidogrel, ASA
- Where
- Sweden
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Congenital Heart Defects, Blood Platelet Disorders
Platelet Aggregation Inhibition in Children on Clopidogrel (PICOLO)
PICOLO is a double blind placebo controlled phase II dose ranging, dose escalating study in patients of Blalock-Taussig age categories (neonates and infants/toddlers), to determine the dose providing inhibition of platelet…
- Trial name
- NCT00115375
- Testing
- Clopidogrel (SR25990)
- Where
- 6 sites in United States, Belgium and 4 more
- Volunteers
- 92 people
- Sponsor
- Sanofi
Platelet Aggregation Inhibitors, NSTEACS
Efficacy and Safety in Patients With Acute Coronary Syndrome Without ST-Segment Elevation
To evaluate the efficasy and safety of SR25990C(loading dose:300mg, maintenance dose:75mg/day) in comparison with the standard Japanese treatment(ticlopidine) in patients with acute coronary syndrome without ST-segment elevation…
- Trial name
- NCT00325390
- Testing
- clopidogrel (SR25990C)
- Where
- Japan
- Volunteers
- 800 people
- Sponsor
- Sanofi
Acute Coronary Syndromes
Clopidogrel as Adjunctive Reperfusion Therapy - Thrombolysis in Myocardial Infarction
The purpose of this study is to determine if the combination of aspirin plus clopidogrel is more effective than aspirin alone in preventing another heart attack, chest pain, stroke or death in people who have already had a heart…
- Trial name
- CLARITY-TIMI28 (NCT00714961)
- Testing
- Clopidogrel (SR25990)
- Where
- 24 sites in United States, Argentina and 22 more
- Volunteers
- 3,491 people
- Sponsor
- Sanofi
Clopidogrel Non-Responsiveness
The Comparison of Effects Between Increased Dose of Clopidogrel and Addition of Cilostazol
To compare the effect of increased dosing of clopidogrel and adding cilostazol to standard dose of clopidogrel after the insertion of drug-eluting stent in patients with clopidogrel resistance
- Trial name
- 4C-DES (NCT00620646)
- Testing
- aspirin, clopidogrel, aspirin, clopidogrel, cilostazol
- Where
- South Korea
- Volunteers
- 80 people
- Sponsor
- Samsung Medical Center
Intermittent Claudication
Mixed Antagonist of Serotonin for Claudication Optimal Therapy
To investigate in patients suffering from intermittent claudication due to Fontaine stage II PAD whether a 24-week treatment by SL650472 OD on top of clopidogrel may result in an improvement of walking capacity, by comparing…
- Trial name
- MASCOT (NCT00300339)
- Testing
- SL650472, Clopidogrel
- Where
- 9 sites in United States, Belgium and 7 more
- Volunteers
- 599 people
- Sponsor
- Sanofi
Gastroduodenal Ulcer
Effect of Naproxen, Aspirin, Celecoxib, or Clopidogrel on the Healing of Stomach and Intestinal Ulcers
Gastroduodenal ulcers are extremely common in the community today. Though much has been written and observed concerning how ulcers form, not much has been described in the human model concerning how these ulcers heal.
- Trial name
- Lesions2 (NCT00778193)
- Testing
- Naproxen, Aspirin, Celecoxib
- Where
- United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Research Associates of New York, LLP
Peripheral Arterial Disease
The Effects of Physical Training, ASA (Aspirin), and Clopidogrel on the Walking Capacity of Patients With Stage II Peripheral Arterial Disease (PAD)
To evaluate the change in walking capacity after a well organized and structured intensive physical training program with supportive pharmacotherapy with Clopidogrel or ASA.
- Trial name
- NCT00189618
- Testing
- Aspirin, Clopidogrel
- Where
- 16 sites in Germany, Switzerland
- Volunteers
- 250 people
- Sponsor
- Arteriogenesis Competence Network
Healthy
Pharmacodynamics of CGT 2168 Compared With Plavix®
CG106 is a Phase I open-label, randomized, multiple-dose, two-way crossover study to characterize the pharmacodynamics and pharmacokinetics of the investigational fixed-dose combination product CGT 2168 (clopidogrel, 75 mg and…
- Trial name
- NCT00620802
- Testing
- CGT-2168, Plavix
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cogentus Pharmaceuticals
Coronary Artery Disease
Clopidogrel and Aspirin Together: The Effect on C-Reactive Protein Trial
Inflammation is associated with worsening outcomes among individuals with CAD; C-reactive protein is a well-known marker of inflammation.
- Trial name
- NCT00343876
- Testing
- aspirin, clopidogrel
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Intermountain Health Care, Inc.
Coronary Artery Disease
Effect of Clopidogrel (Plavix) on Postoperative Bleeding in Patients Undergoing Coronary Artery Bypass Surgery.
Running title: Effect of Clopidogrel on Postoperative Bleeding in Patients undergoing Coronary Artery Bypass Surgery Title: Clopidogrel and bleeding in patients undergoing coronary artery bypass grafting.
- Trial name
- NCT00724880
- Testing
- Clopidogrel
- Volunteers
- 135 people
- Sponsor
- Catharina Ziekenhuis Eindhoven
Coronary Artery Disease
Healthy Volunteer Study of Clopidogrel and Rifampicin
The principal research question is: Can platelet P2Y12 receptor blockade by the antithrombotic drug clopidogrel be significantly enhanced by coadministration of the antibiotic rifampicin? Clopidogrel is an antithrombotic drug in…
- Trial name
- NCT00696566
- Testing
- Clopidogrel and Rifampicin
- Where
- United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Myocardial Infarction
Warfarin After Anterior ST-Elevation Myocardial Infarction
Following severe heart attacks involving the front wall of the heart (anterior myocardial infarction), patients are at risk of developing blood clots in the main pumping chamber that can cause a stroke.
- Trial name
- NCT00662467
- Testing
- aspirin + clopidogrel, aspirin + clopidogrel + warfarin
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Hamilton Health Sciences Corporation
Transient Ischemic Attack, Stroke
Fast Assessment of Stroke and Transient Ischemic Attack to Prevent Early Recurrence (FASTER)
Current management of patients with TIA (transient ischemic attack) or minor stroke includes the prompt investigation and treatment in the days and weeks after the event.
- Trial name
- NCT00109382
- Testing
- Aspirin, Clopidogrel, Simvastatin
- Where
- 18 sites in United States, Canada
- Volunteers
- 500 people
- Sponsor
- University of Calgary
Peripheral Arterial Disease
Effect of Plavix on NO (Nitrogen Monoxide) Production of the Endothelial Function
To determine whether in the laser Doppler flowmetric parameters characteristic of endothelial dysfunction at patients with clinically manifest atherosclerosis any change can be detected at plavix (clopidogrel) treatment.
- Trial name
- NCT00648453
- Testing
- Clopidogrel (Plavix)
- Where
- Hungary
- Volunteers
- 39 people
- Sponsor
- Sanofi
Ischemic Heart Disease
Clopidogrel Only Before Percutaneous Coronary Intervention or Before Every Coronarography?
Clopidogrel pre-treatment before planned percutaneous coronary intervention was proved to reduce periprocedural complications. However, the vast majority of patients in the current interventional cardiology practice do not…
- Trial name
- NCT00432120
- Testing
- clopidogrel
- Where
- Czechia
- Sponsor
- Charles University, Czech Republic