Clinical trials: Cognitive Behavioral Therapy
Methamphetamine Dependence, Substance Abuse
Varenicline vs Placebo for the Treatment of Methamphetamine Dependence
Methamphetamine (MA) abuse is the fastest growing drug problem in the United States and is responsible for significant public health complications, including HIV infection.
- Conditions
- Methamphetamine Dependence, Substance Abuse, Methamphetamine Abuse
- Trial name
- RAVEN (NCT01011829)
- Testing
- Varenicline
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of California, Los Angeles
Tobacco Smoking
Heart Rate Variability Biofeedback for Smoking Cessation Treatment
The purpose of the study is to conduct an open trial examining the feasibility and acceptability of an adapted heart rate variability biofeedback and smoking cessation treatment that was using a primarily virtual remote…
- Trial name
- HRVB-SCT (NCT05224050)
- Testing
- Cognitive-Behavioral Smoking Cessation, Heart Rate Variability Biofeedback, Nicotine patch
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Stigmatization, Obesity
Psychological Intervention to Reduce Weight Bias Internalization
This is a randomized controlled trial to test the effects on WBI of a novel psychological intervention combined with standard behavioral weight loss (BWL) treatment, as compared to BWL alone.
- Conditions
- Stigmatization, Obesity, Weight Loss
- Trial name
- NCT03572218
- Testing
- BWL, BIAS
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- University of Pennsylvania
Musculoskeletal Pain, Chronic Pain
Living in Full Even With Pain Study
This project will increase our understanding of the mechanisms underlying changes in opioid medication use associated with three psychosocial chronic pain (CP) treatments.
- Trial name
- LIFE (NCT03916276)
- Testing
- Cognitive Therapy (CT), Mindfulness Meditation (MM), Behavioral Activation (BA)
- Where
- United States
- Volunteers
- 91 people
- Sponsor
- University of Washington
Obstructive Sleep Apnea, PTSD
Cognitive Behavioral Therapy to Increase CPAP Adherence in Veterans With PTSD
Approximately 20 million Americans suffer from Obstructive Sleep Apnea (OSA) creating risks for major health problems, including dementia, heart attack, and stroke.
- Conditions
- Obstructive Sleep Apnea, PTSD, Posttraumatic Stress Disorder
- Trial name
- NCT02641496
- Testing
- CBT-OSA, Sleep Education
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Autism, Asperger's Syndrome
Cognitive Behavioral Therapy for Anxiety Disorders in Adolescents With Autism
Due to the considerable prevalence of anxiety in youth with autism spectrum disorders, this study seeks to establish the efficacy of a modified cognitive behavioral therapy protocol in 50 adolescents versus other available…
- Conditions
- Autism, Asperger's Syndrome, Pervasive Developmental Disorder Not Otherwise Specified, Generalized Anxiety Disorder
- Trial name
- NCT01563003
- Testing
- Cognitive Behavioral Therapy, Treatment as usual
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Multiple Sclerosis
Cognitive Behavioral Therapy, Modafinil, or Both for Multiple Sclerosis Fatigue
This clinical trial will compare the effectiveness of 3 treatments for fatigue in Multiple Sclerosis: 1) a commonly used behavioral treatment strategy (telephone-based cognitive behavioral therapy), 2) a commonly used medication…
- Trial name
- COMBO-MS (NCT03621761)
- Testing
- Telephone-based Cognitive Behavioral Therapy, Modafinil
- Where
- 2 sites in United States
- Volunteers
- 343 people
- Sponsor
- University of Michigan
PTSD
Treatment of PTSD in Residents of Battered Women's Shelters
This is a study comparing a new treatment (HOPE) to supportive therapy in the treatment of PTSD in residents of battered women's shelters.
- Trial name
- HOPE (NCT02398227)
- Testing
- HOPE, PCT
- Where
- United States
- Volunteers
- 172 people
- Sponsor
- The University of Akron
Post-Traumatic Stress Disorders, Opiate Use Disorder
Optimal Treatment of Veterans With PTSD and Comorbid OUD
The objective of this study is to test a standard psychotherapy for PTSD in Veterans who also suffer from Opiate Use Disorder (OUD).
- Trial name
- NCT03605342
- Testing
- Buprenorphine, Cognitive Processing Therapy (CPT), Individual Drug Counseling (IDC)
- Where
- 2 sites in United States
- Volunteers
- 38 people
- Sponsor
- VA Office of Research and Development
Insomnia, Depression
A Novel Use of a Sleep Intervention to Target the Emotion Regulation Brain Network to Treat Depression and Anxiety
Several lines of evidence suggest that unhealthy sleep patterns contribute to depressive symptoms through disruption of brain networks that regulate emotional functions.
- Trial name
- NCT04424407
- Testing
- Cognitive Behavioral Therapy for Insomnia
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- Stanford University
Major Depressive Disorder
Quantitative Electroencephalogram (QEEG) Predictors of Response to Psychotherapy Versus Antidepressant Treatment in Depression
The purpose of this research study is to find out if a test can predict whether someone with depression will get better with treatment.
- Trial name
- NCT00824044
- Testing
- Cognitive Behavioral Therapy (CBT), Escitalopram
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- Massachusetts General Hospital
Distress, Anxiety
Acceptance and Commitment Therapy (ACT) for OEF/OIF Veterans
This trial compares two psychotherapies, Acceptance and Commitment Therapy (ACT) and Present Centered Therapy (PCT), for veterans of the conflicts in Iraq and Afghanistan.
- Conditions
- Distress, Anxiety, Depression, Postconcussive Symptoms
- Trial name
- NCT01253044
- Testing
- Acceptance and Commitment Therapy, Present Centered Therapy
- Where
- 6 sites in United States
- Volunteers
- 160 people
- Sponsor
- Veterans Medical Research Foundation
Post-traumatic Stress Disorder
Cognitive Behavioral Treatments for Post-traumatic Stress Disorder (PTSD) Sleep Disturbance
The purpose of this study is to compare the effectiveness of two cognitive behavioral group psychotherapy interventions in controlling the subjective sleep disturbance in veterans with Post-traumatic Stress Disorder.
- Trial name
- NCT00108628
- Testing
- Imagery Rehearsal, Sleep and Nightmare Management
- Where
- United States
- Volunteers
- 134 people
- Sponsor
- US Department of Veterans Affairs
Fall, Fear of Falling
Optimizing a Technology-based Body and Mind Intervention
Older adults may feel at risk for falling, but do not have a physical risk of falling. On the other hand, some older adults may not feel at risk for falling, but do have a physical risk of falling.
- Conditions
- Fall, Fear of Falling, Physical Inactivity, Sedentary Behavior
- Trial name
- NCT05778604
- Testing
- Physio-feedback, Cognitive reframing, Peer-led exercises
- Where
- United States
- Volunteers
- 403 people, healthy volunteers welcome
- Sponsor
- University of Central Florida
Insomnia
Effectiveness of eCBT-I on Improving Mental Health in Chinese Youths With Insomnia
This study aims to conduct a randomized control trial to validate the treatment effect of e-based cognitive behavioral therapy for Insomnia (e-CBT-I) on insomnia disorder, and explore whether e-CBT-I could prevent depression and…
- Trial name
- NCT04069247
- Testing
- e-CBT-I, e-HE
- Where
- 2 sites in China, Hong Kong
- Volunteers
- 708 people
- Sponsor
- Chinese University of Hong Kong
Posttraumatic Stress Disorder
Telemedicine Outreach for Post Traumatic Stress in CBOCs
The purpose of this study is improved outcomes for veterans with Post Traumatic Stress Disorder (PTSD) treated in small VA Community Based Outpatient Clinics (CBOCs).
- Trial name
- TOP (NCT00821678)
- Testing
- Telemedicine Outreach for PTSD
- Where
- 3 sites in United States
- Volunteers
- 265 people
- Sponsor
- VA Office of Research and Development
Opioid-use Disorder
Disclosure Intervention for People in Recovery From Opioid Use Disorder
Many people with substance use disorders struggle with decisions regarding whether to disclose to others that they have a history of substance use and/or are in recovery.
- Trial name
- NCT04836247
- Testing
- Disclosing Recovery: A Decision Aid and Toolkit, Mindfulness
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Delaware
Cigarette Smoking, Nicotine Dependence
Treatment of Smoking Among Individuals With PTSD
This study will examine the effect of combining prolonged exposure, a cognitive-behavioral treatment program for post-traumatic stress disorder (PTSD) with medication (varenicline) and counseling treatments for smoking cessation.
- Conditions
- Cigarette Smoking, Nicotine Dependence, Post-traumatic Stress Disorder, Tobacco Use Disorder
- Trial name
- NCT00937235
- Testing
- Varenicline, Medication Management Counseling, Prolonged Exposure
- Where
- United States
- Volunteers
- 142 people
- Sponsor
- University of Pennsylvania
Substance Use Disorders
Adaptive Treatment for Alcohol and Cocaine Dependence
1. Primary objective #1: Determine the relative effectiveness of MI-IOP and MI-PC in the full study sample with regard to treatment engagement over weeks 1-12 and cocaine/alcohol use over weeks 1-24.
- Trial name
- NCT01032135
- Testing
- Motivational Interviewing, Telephone counseling, Cognitive Behavioral Therapy (CBT) Counseling
- Where
- 3 sites in United States
- Volunteers
- 500 people
- Sponsor
- University of Pennsylvania
Obsessive-Compulsive Disorder
Treatment of Obsessive Compulsive Disorder in Children
This study will determine whether cognitive behavioral therapy delivered by either psychologists or psychiatrists can improve the effectiveness of serotonin reuptake inhibitor treatment in children with obsessive compulsive…
- Trial name
- NCT00074815
- Testing
- Serotonin reuptake inhibitors management, Cognitive behavioral therapy by a psychologist, Instructional cognitive behavioral therapy by a psychiatrist
- Where
- 3 sites in United States
- Volunteers
- 124 people
- Sponsor
- Duke University