Clinical trials: Cognitive training
Transcranial Direct Current Stimulation
Noninvasive Transcranial Direct Current Stimulation to Improve Executive Functions in Stroke Patients. MODUL-EXE Clinical Trial.
This study will examine the possible effects of tDCS (Transcranial Direct Current Stimulation) treatment to the left DLPFC on executive functions in patients with an acute stroke affecting the frontal lobe or the basal ganglia.
- Trial name
- MODUL-EXE (NCT05628818)
- Testing
- Transcranial Direct Current Stimulation (tDCS)
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Fundación Pública Andaluza para la Investigación Biomédica Andalucía Oriental
Aging, Sarcopenia
Effect of Immunocal® With Exercise Versus Casein With Exercise on Aging Processes in Elderly Persons
Aging is typically associated with a decrease in skeletal muscle mass and muscle function, which contributes decisively to disability in old age and to the loss of quality of life.Resistance exercise can increase muscle strength…
- Trial name
- NCT00935610
- Testing
- Immunocal, Casein
- Where
- Canada
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Immunotec Inc.
Osteo Arthritis Knee, Knee Arthroplasty
Effects of Motor Imagery Intervention on Functional Recovery Following Total Knee Arthroplasty
The knee osteoarthritis becoming a leading cause of disability among older adults' population. When conventional treatments fail, a total knee arthroplasty (TKA) is suggested.
- Trial name
- KSV2017 (NCT03684148)
- Testing
- Motor imagery practice
- Where
- Slovenia
- Volunteers
- 34 people
- Sponsor
- Science and Research Centre Koper
Physical Activity
Training Intervention in Heart Failure and Frail Elderly Population
There is enough scientific evidence of the benefits detection of frailty in patients with heart failure, which is an important prognostic factor.
- Trial name
- TIHFEP (NCT02365155)
- Testing
- Multicomponent training intervention., Nutrition intervention, Cognitive intervention
- Where
- Spain
- Volunteers
- 150 people
- Sponsor
- Hospital de la Ribera
Schizophrenia, Schizoaffective
Cognitive Remediation and Social Skills Training in Schizophrenia
The purpose of this study is to examine whether patients who participate in cognitive remediation prior to a skills training program learn and perform the skills better than patients who do not participate in cognitive…
- Trial name
- NCT00223535
- Testing
- Cognitive Remediation, Social Skills Training
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Schizophrenia, Schizoaffective Disorder
Improving Adherence to Oral Antipsychotic Medications in People With Schizophrenia
This study will determine the comparative effectiveness of two systems designed to improve medication adherence in people with schizophrenia.
- Trial name
- NCT00406718
- Testing
- Med-eMonitor, PharmCAT, Treatment as Usual
- Where
- United States
- Volunteers
- 197 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Motor Coordination or Function; Developmental Disorder
Project for Cognitive Advancement in Infants With Neuromotor Disorders
The purpose of this longitudinal study is to examine the ongoing interaction between the domains of cognitive and motor development in infants with neuromotor disability, and to compare outcomes of two groups of infants receiving…
- Trial name
- CAN-Do (NCT02673658)
- Testing
- Motor + problem solving, body weight support training
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Duquesne University
TBI (Traumatic Brain Injury)
The Development of a Virtual Reality Program to Improve Attention in Individuals With TBI
The purpose of this research is to investigate the effectiveness of a technique designed to improve divided attention and set-shifting impairments in persons with a traumatic brain injury (TBI).
- Trial name
- NCT03605017
- Testing
- Virtual Reality Executive Function Training (VREFT)
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Kessler Foundation
Mild Cognitive Impairment
Study of the Effects of Adapted Tango and Multidimensional Intervention in pREvention of Dementia in agiNG (STRENGTH)
The STRENGTH project is a randomized controlled trial to assess the effects of a 6 months multimodal intervention consisted of adapted Tango dancing together with music therapy, engagement in social activities, cognitive…
- Trial name
- STRENGTH (NCT04146818)
- Testing
- Adapted Tango Dancing, Control
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- Istituto Nazionale di Ricovero e Cura per Anziani
HIV Prevention
Behavioral Economic Intervention to Improve HIV Behaviors in Sexual Minority Individuals
This research study is testing a new behavioral therapy called Episodic Future Thinking or EFT can help people reduce drug use and risky sexual behaviors while helping them adhere to their HIV prevention medication (PrEP).
- Trial name
- NCT06745947
- Testing
- EFT
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
Suicide, Attempted
Ketamine + Cognitive Training for Suicidality in the Medical Setting
This project seeks to identify the acute and longer-term impact of a single dose of intravenous ketamine among suicidal patients referred for psychiatric consultation/liaison in the medical inpatient setting.
- Trial name
- NCT04578938
- Testing
- Intravenous ketamine, Cognitive training
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Rebecca Price
Anhedonia, Depression
Computational Cognitive Training To Boost Reward Responsiveness In Anhedonic Patients
Anhedonia, i.e., reduced positive mood and decreased sensitivity to rewards, is observed in many psychiatric illnesses, particularly depression and anxiety disorders.
- Trial name
- NCT05383248
- Testing
- High Reward - High Variance, High Reward - Low Variance
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of California, San Diego
Major Depressive Disorder
Cognitive Training for Depression II
This study is evaluating the effects of two brain training exercises on: memory, cognitive processing and depression symptoms.
- Trial name
- NCT01934491
- Testing
- Cognitive Training A, Cognitive Training B
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Mild Cognitive Impairment, Cognitive Decline
Exercise in Adults With Mild Memory Problems
This study evaluates the effects of physical exercise on cognition, functional status, brain atrophy and blood flow, and cerebrospinal fluid biomarkers of Alzheimer's disease in adults with a mild memory impairment.
- Conditions
- Mild Cognitive Impairment, Cognitive Decline, Memory Impairment
- Trial name
- EXERT (NCT02814526)
- Testing
- Aerobic exercise, Stretching/balance/range of motion exercise
- Where
- 14 sites in United States
- Volunteers
- 296 people
- Sponsor
- Alzheimer's Disease Cooperative Study (ADCS)
Shyness, Wellbeing
Improving Social Anxiety Symptoms (SocWell)
The investigators will test the value of an internet self-help package (E-Couch) for alleviating social anxiety symptoms in the general population.
- Trial name
- SocWell (NCT02451878)
- Testing
- E-Couch
- Where
- 2 sites in Australia, United Kingdom
- Volunteers
- 2,105 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Sleep Initiation and Maintenance Disorders
Mechanisms of Change in Cognitive Behavioral Therapy for Insomnia (CBTi)
The purpose of this study is to investigate the mechanisms of change in Cognitive Behavioral Therapy for insomnia (CBTi) in a sample of adults aged 50-65.
- Trial name
- CBTi (NCT05226585)
- Testing
- In-Person Cognitive Behavioral Therapy for Insomnia, Telehealth Cognitive Behavioral Therapy for Insomnia, Internet Cognitive Behavioral Therapy for Insomnia
- Where
- United States
- Volunteers
- 93 people
- Sponsor
- University of Arizona
Metabolic Syndrome (MetS)
Effectiveness of the Personalized Responses & Integrated Systems for Metabolism (PRISM) on Improving Insulin Resistance Among Adults With Metabolic Syndrome: A Pilot Study (PRISM-I)
The primary objective of the Personalized Responses \& Integrated Systems for Metabolism (PRISM-I) pilot study is to assess the feasibility of conducting a definitive randomized controlled trial evaluating precision lifestyle…
- Trial name
- PRISM-I (NCT07710274)
- Testing
- Time-restricted eating, Physical Activity, Low Glycemic Load diet
- Where
- Singapore
- Volunteers
- 200 people
- Sponsor
- National University Health System, Singapore
Breast Cancer, Breast Neoplasm Female
High-intensity Exercise After Treatment
This pilot study tests the feasibility and preliminary efficacy of an 8-week, 3-arm pilot exercise trial in which 45 breast cancer survivors will be randomized to high-intensity interval training (HIIT; n=15), moderate-intensity…
- Trial name
- HEAT (NCT04950010)
- Testing
- High-Intensity Interval Training, Moderate-Intensity Exercise
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- University of Nebraska
Schizophrenia, Schizoaffective Disorder
Comparing Cognitive Remediation Approaches for Schizophrenia
This research compares the relative efficacy of two empirically-supported, standardized programs of cognitive remediation for treatment of cognitive deficits and community function in schizophrenia to help inform best practices.
- Trial name
- NCT04123223
- Testing
- Cognitive Remediation, Computer Games
- Where
- 2 sites in United States
- Volunteers
- 135 people
- Sponsor
- Wesleyan University
Brain Injuries, Traumatic
Mild TBI Assessment & Rehabilitation
One of the most pressing concerns within the VA currently is the provision of interventions that address the cognitive as well as emotional problems faced by Veterans with mild TBI and comorbid conditions.
- Trial name
- MTAR (NCT02920788)
- Testing
- Goal-Oriented Attentional Self-Regulation (GOALS), Brain Health Education (BHE), fMRI
- Where
- 2 sites in United States
- Volunteers
- 65 people
- Sponsor
- VA Office of Research and Development
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