Clinical trials: Cognitive training
Aging, MCI
Enhancing Attention and Wellbeing Using Digital Therapeutics
The goals of the proposed research are to first determine the minimal and/or optimal dose of a digital intervention required for cognitive enhancement, and then to examine the impact of several potential moderators of treatment…
- Conditions
- Aging, MCI, Cognitive Decline
- Trial name
- NCT06397469
- Testing
- MediTrain, Worder
- Where
- United States
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Schizophrenia
Predictors of Response to Cognitive Remediation in Schizophrenia
The purpose of this study is to determine which variables predict improvement on a cognitive training task battery, used for patients with schizophrenia, and to determine the proportion of patients whose performance returns to…
- Trial name
- NCT00333970
- Testing
- cognitive remediation
- Where
- United States
- Volunteers
- 103 people
- Sponsor
- US Department of Veterans Affairs
SMA
A Head-to-head Study Comparing the Functional Value of Two Models of Robotically Assisted Rehabilitation in SMA (Spinal Muscular Atrophy) Patients
A head-to-head study comparing the functional value of two models of robotically assisted rehabilitation in patients with SMA. A single-center, randomized, single-blinded, comparative study of Robotically Assisted Verticalization…
- Trial name
- SMArt (NCT06322654)
- Testing
- Robotically Assisted Locomotion, Robotically Assisted Verticalization
- Where
- Poland
- Volunteers
- 200 people
- Sponsor
- Wiktor Dega University Orthopedic and Rehabilitation Hospital
Alzheimer Disease, Frontotemporal Degeneration (FTD)
PST for Care Partners of Adults With Alzheimer's and Alzheimer'S-related Dementia
Caregivers of individuals with Alzheimer's disease and related dementia rarely get the preparation or training they need to manage their caregiving responsibilities and to successfully balance their own self-care and their…
- Conditions
- Alzheimer Disease, Frontotemporal Degeneration (FTD), Lewy Body Dementia (LBD), Vascular Contributions to Cognitive Impairment and Dementia (VCID)
- Trial name
- NCT04748666
- Testing
- Problem Solving Training
- Where
- 3 sites in United States
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Stroke
Cognitive & Motor Training After Stroke For Everyday Walking Restoration
The purpose of this study is to test a unique, combined cognitive and motor intervention designed to restore safe, more normal coordinated gait components into the real world environment for individuals with stroke.
- Trial name
- NCT01160653
- Testing
- FES-IM, Cognitive training
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Breast Cancer
Understanding and Addressing Disparities in Cancer Therapy Induced Inflammation and Associated Endothelial Dysfunction
Very little is understood about the off-target vascular mechanisms of anti-cancer drug toxicity and the impact of exercise on these changes.
- Trial name
- DECODE (NCT05223322)
- Testing
- Taking Charge during Treatment (TCT) Intervention
- Where
- 2 sites in United States
- Volunteers
- 80 people
- Sponsor
- Medical College of Wisconsin
Randomised Controlled Trial, Major Neurocognitive Disorder
Exergaming in People With Major Neurocognitive Disorder
This randomized controlled trial explores the efficacy of an 8-week standing exergaming program in people with major neurocognitive disorder (MNCD) residing in long-term care facilities.
- Conditions
- Randomised Controlled Trial, Major Neurocognitive Disorder, Long-term Care Facility, Physical Activity
- Trial name
- NCT04436302
- Testing
- Exergame device
- Where
- Belgium
- Volunteers
- 50 people
- Sponsor
- Davy Vancampfort
Chronic Heart Failure, Chronic Obstructive Pulmonary Disease
Cognitive Impairment, Frailty and Rehabilitative Outcome in Older Patients Affected by Cardiorespiratory Disease
A consistent number of studies in the last few years highlighted that the functional and clinical worsening in patients with cardiac and/or respiratory disease/s increase the risk of cognitive decline.
- Trial name
- NCT05230927
- Testing
- Multidisciplinary Rehabilitation
- Where
- Italy
- Volunteers
- 240 people
- Sponsor
- Antonia Pierobon
Diabetes Mellitus Type 2 - Insulin-Treated
My Dose Coach Mobile App to Support Insulin Titration and Maintenance
The purpose of this research study is to evaluate an electronic application (app) designed to help people with type 2 diabetes (T2DM) adjust their insulin doses. The app is called My Dose Coach.
- Trial name
- NCT04678661
- Testing
- Smartphone application and web portal, Standard Insulin Therapy Education
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Linda Siminerio
Cognitive Impairment, Dementia
Multidimensional Rehabilitation Programs for Cognitive Impairment in Comorbid Outpatients: a Randomized Controlled Trial
Dementias secondary to cerebrovascular diseases are of significant epidemiological and clinical relevance. As a result, the management of individuals with comorbid dementia should involve early diagnosis, effective treatment, and…
- Conditions
- Cognitive Impairment, Dementia, Comorbidities and Coexisting Conditions, Vascular Dementia
- Trial name
- RCTCogRehab (NCT05954741)
- Testing
- Motor rehabilitation alone, Motor rehabilitation and Cognitive rehabilitation (paper-based), Motor rehabilitation and cognitive rehabilitation (digital-based)
- Where
- Italy
- Volunteers
- 75 people
- Sponsor
- Istituti Clinici Scientifici Maugeri SpA
Children
Effect of Cognitive-motor Training Versus Pilates Exercises on Postural Stability in Down Syndrome.
The study will be randomized clinical trial. Data will be collected from City hospital, Mirpur AJK. Total thirty two subjects will be assigned randomly by using lottery randomization into two groups.
- Trial name
- NCT07428837
- Testing
- cognitive-motor training, pilates exercises
- Where
- Pakistan
- Volunteers
- 32 people
- Sponsor
- Riphah International University
Alzheimer Disease
Effectiveness of a High-intensity Interval Exercise Program in People With Alzheimer's
Alzheimer's disease (AD) is a the most common type of dementia. It is a progressive disease that affects different areas of human behavior at the cognitive, social, physical and metabolic levels.
- Trial name
- NCT05691842
- Testing
- HIIT intervention, Dual task intervention
- Where
- Spain
- Volunteers
- 66 people
- Sponsor
- University of Valencia
Cognitive Training, Dementia
Multi-component Cognitive Intervention for Older Adults With Mixed Cognitive Abilities
Objective: To assess the feasibility and preliminary effectiveness of an evidence-driven, pragmatic multi-component cognitive intervention with simulated everyday tasks (MCI-SET) with an inclusive group design in community…
- Conditions
- Cognitive Training, Dementia, Occupational Therapy, Aging
- Trial name
- NCT04615169
- Testing
- Multi-component cognitive intervention with simulated everyday tasks (MCI-SET)
- Where
- Taiwan
- Volunteers
- 140 people
- Sponsor
- National Cheng Kung University
Alcohol Use Disorder
Severe Alcohol-use Disorder: a tDCS and Response Inhibition Training Intervention
Most severe forms of alcohol-use disorder are thought to reflect an abnormal interplay between two neural systems: an overly active impulsive one driven by immediate rewards prospects and a weak reflective one, tuned on long-term…
- Trial name
- ALCOSTIM (NCT03447054)
- Testing
- Combined TDCS active and ICT active, Combined TDCS active and ICT inactive
- Where
- Belgium
- Volunteers
- 136 people
- Sponsor
- Brugmann University Hospital
Mild Cognitive Impairment, Caregivers
iMeditate at Home for Older Adults With Mild Cognitive Impairment and Caregivers
Individuals diagnosed with mild cognitive impairment (MCI) are at a high risk of developing dementia and are an important target population for interventions that may reduce the risk of cognitive decline.
- Trial name
- NCT04184037
- Testing
- Mindfulness meditation delivered via a mobile app
- Where
- Canada
- Volunteers
- 9 people
- Sponsor
- Baycrest
Amnestic Mild Cognitive Impairment, Aging
Recollection Training in Healthy Older Adults and Older Adults With Amnestic Mild Cognitive Impairment
We have developed a training intervention that successfully improves older adults' memory. We have also shown that older adults whose memory is as good as younger adults' memory (Hi-Old) use an altered pattern of memory-related…
- Trial name
- NCT00643266
- Testing
- Recollection Training, Control
- Where
- Canada
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Baycrest
Stroke
Time Pressure Motor Training With Step Square Exercise on Stroke Patients
to investigate The Efficacy of Time Pressure motor rehabilitation with step square exercise (SEE) on decision making ability \& quality of life in stroke Patients
- Trial name
- NCT06990451
- Testing
- time pressure, step square exercise, functional care training
- Where
- Egypt
- Volunteers
- 38 people
- Sponsor
- October 6 University
Schizophrenia Spectrum and Other Psychotic Disorders
Mindfulness, Empathy and the Oxytocinergic System in Persons With Schizophrenia
Recent studies indicated positive effects of mindfulness-based interventions (MBI) for schizophrenia (SCZ), but also on oxytocin (OXT) levels in healthy persons.
- Trial name
- OXYGEN (NCT05491486)
- Testing
- Mindfulness-based Group Therapy
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- Charite University, Berlin, Germany
Traumatic Brain Injury, Closed Traumatic Brain Injury
The Effects of Transcranial Direct Current Stimulation (tDCS) and Cognitive Training in Patients With TBI
Long-term sequelae in TBI is a well-recognized burn. We designed a proof of concept study, randomized, double-blind, placebo-controlled to evaluate 36 adult TBI patients.
- Conditions
- Traumatic Brain Injury, Closed Traumatic Brain Injury, Severe Brain Injury
- Trial name
- NCT04540783
- Testing
- Transcranial direct current stimulation (tDCS)
- Where
- Brazil
- Volunteers
- 36 people
- Sponsor
- University of Sao Paulo General Hospital
Cognitive Impairment, Schizophrenia
Cognitive Rehabilitation in Schizophrenia
The study will investigate the viability of two cognitive rehabilitation strategies to improve functional outcomes for people with schizophrenia.
- Trial name
- NCT00248794
- Testing
- Cognitive Rehabilitation Therapy (CRT) + Skill Training (SDG), Individual Computer Based Cognitive Rehabilitation (ICBCR) and Skills Training (SDG), Skills Group (SDG)
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- VA Office of Research and Development
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