Clinical trials: Computed Tomography
Castration-Resistant Prostate Carcinoma, Metastatic Prostate Carcinoma
Bipolar Androgen Therapy to Restore Sensitivity to Androgen Deprivation Therapy for Patients With Metastatic Castration Resistant Prostate Cancer
This phase I trial tests the change in androgen receptor sensitivity, side effects and effectiveness of bipolar androgen therapy, using testosterone, in patients with castration resistant prostate cancer that has spread to other…
- Conditions
- Castration-Resistant Prostate Carcinoma, Metastatic Prostate Carcinoma, Stage IVB Prostate Cancer AJCC v8
- Trial name
- NCT06305598
- Testing
- Biopsy, Bone Scan, Computed Tomography
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Roswell Park Cancer Institute
Head and Neck Carcinoma
Bioelectrical Impedance Analysis in Estimating Body Composition in Patients With Stage I-IV Head and Neck Cancer Undergoing Radiation Therapy
Bioelectrical impedance analysis measures body mass (the amount of muscle and fat in the body) and the level of hydration to help researchers identify patients who are losing muscle mass during radiation therapy.
- Trial name
- NCT02615275
- Testing
- Bioelectric Impedance Analysis, Computed Tomography, Positron Emission Tomography
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- M.D. Anderson Cancer Center
Spontaneous Intracranial Hypotension
Blind Versus Targeted Epidural Patch With Autologous Platelet-rich Plasma for Spontaneous Intracranial Hypotension
Spontaneous intracranial hypotension (SIH) is a condition characterized by refractory orthostatic headache, mostly due to loss of cerebrospinal fluid (CSF).
- Trial name
- NCT07283536
- Testing
- Targeted epidural PRP patch, Blind epidural PRP patch
- Sponsor
- Beijing Tiantan Hospital
Aortic Dissection, Aortic Arch
Repair Versus Non-repair of the Aortic Arch in Type A Aortic Dissection
Acute Stanford type A aortic dissection (TAAD) is a life-threatening clinical status requiring surgery that is usually performed as a salvage procedure.We planned a multicenter study to evaluate the balance between the patient's…
- Conditions
- Aortic Dissection, Aortic Arch, Aortic Dissection Rupture, Aortic Dilatation
- Trial name
- AoArch (NCT05912634)
- Testing
- Conservative TAAD-R, Extensive TAAD- R
- Where
- France
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- Centre Cardiologique du Nord
Meningioma, Meningioma, Malignant
Adjuvant Hypofractionated Stereotactic Radiosurgery for Intermediate-risk Meningioma
This clinical trial tests the safety and effectiveness of hypofractionated stereotactic radiosurgery for treating patients who have undergone surgical resection for grade II meningiomas or grade I meningiomas that have come back…
- Conditions
- Meningioma, Meningioma, Malignant, Recurrent Meningioma
- Trial name
- SRS-AIM (NCT06557512)
- Testing
- Hypofractionated Stereotactic Radiosurgery (SRS), Magnetic Resonance Imaging (MRI), Computed Tomography (CT)
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- University of California, San Francisco
Rhabdomyosarcoma, Non-Rhabdo. Soft Tissue Sarcoma
Molecular-Functional Imaging of Hypoxia in Childhood Sarcomas
This study will test the feasibility of using novel/existing imaging technologies focused on hypoxia measurements to determine "response to therapy" in pediatric soft tissue sarcomas as a pilot study.
- Trial name
- NCT03054792
- Testing
- Blood Oxygen Level Dependent [BOLD] MRI, Diffusion-Weighted [DW] MRI, Magnetic Resonance Spectroscopy [MRS]
- Where
- Canada
- Volunteers
- 18 people
- Sponsor
- The Hospital for Sick Children
SARS-COV2, Severe Acute Respiratory Syndrome
Beaumont Quantitative Lung Function Imaging to Characterize Patients With SARS-COV 2
The goal of this study is to evaluate if CT (Computerized Tomography) can effectively and accurately predict disease progression in patients with SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2).
- Conditions
- SARS-COV2, Severe Acute Respiratory Syndrome, COVID-19
- Trial name
- NCT04320511
- Testing
- CT-V
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Corewell Health East
ARDS, Respiratory Failure
Hospital-wide Incidence, Clinical Characteristics and Outcomes of ARDS
The Acute Respiratory Distress Syndrome (ARDS) impacts one of every four patients requiring mechanical ventilation for respiratory support and carries a mortality rate of 40%.
- Conditions
- ARDS, Respiratory Failure, Lung Ultrasound
- Trial name
- NCT03546699
- Testing
- Estimation of hospital-wide incidence of ARDS
- Where
- 4 sites in United States, Canada and 1 more
- Volunteers
- 9,999 people
- Sponsor
- University Health Network, Toronto
Primary Aldosteronism
68Ga-Pentixafor PET/CT Versus Adrenal Vein Sampling in Primary Aldosteronism: The GAPA Randomized Clinical Trial
To compare the 68Ga-Pentixafor PET/CT and adrenal vein sampling on the long-term outcomes of primary aldosteronism (PA) patients with adrenal nodule (≥1cm)
- Trial name
- GAPA (NCT06238232)
- Testing
- 68Ga-Pentixafor PET/CT
- Where
- China
- Volunteers
- 320 people
- Sponsor
- Chongqing Medical University
Heart Diseases
Patterns of Coronary Artery Anatomy in Children With Congenital Heart Disease by Computed Tomography
To test the ability of electron beam CT in evalting the coronary artery pattern in children with congenital heart disease.
- Trial name
- NCT00167011
- Testing
- CT
- Where
- Taiwan
- Volunteers
- 200 people
- Sponsor
- National Taiwan University Hospital
Gastroenteropancreatic Neuroendocrine Tumors
68Ga-OPS202 Study for Diagnostic Imaging of GEP NET
The purpose of this study is to assess the safety and tolerability of 68Ga-OPS202 used for the diagnosis of gastroenteropancreatic neuroendocrine tumors (GEP NETs).
- Trial name
- NCT02162446
- Testing
- satoreotide trizoxetan
- Where
- Switzerland
- Volunteers
- 12 people
- Sponsor
- Ipsen
Metastatic Prostate Cancer
The Present Study Aims to Compare Patients Who Receive the Investigational Product (177Lu-DOTA-rosopatamab) Plus Standard of Care, in Comparison to Standard of Care Only
This multinational, multicenter, prospective, randomized, controlled, open label Phase 3 study is designed to investigate and confirm the benefits and risks associated with the PSMA-targeted antibody, 177Lu DOTA rosopatamab…
- Trial name
- NCT04876651
- Testing
- 177Lu-DOTA-rosopatamb, Standard of Care
- Where
- 6 sites in Australia, New Zealand
- Volunteers
- 16 people
- Sponsor
- Telix Pharmaceuticals (Innovations) Pty Ltd
Non Small Cell Lung Cancer
AIMN Multicenter Study: 18 F-FDG PET-CT With or Without Contrast Medium in the Staging and Radiation of Lung Cancer?
Accurate staging of patients with non-small cell cancer (NSCLC) is of fundamental importance both for the correct choice of treatment plan and for prognosis.
- Trial name
- NCT06168916
- Testing
- PET/CT with contrast medium in a single session.
- Volunteers
- 14 people
- Sponsor
- IRCCS San Raffaele
Esophageal Cancer, Esophageal Neoplasms
Assessment of Response to nCRT for GEJ Cancer Using a Fully Integrated PET/MRI
Evaluate the potential role of PET/MRI as a predictor of esophageal and junctional cancers in response to neoadjuvant chemoradiotherapy (nCRT).
- Trial name
- Escape (NCT04359732)
- Testing
- hybrid PET/MRI
- Where
- Italy
- Volunteers
- 121 people
- Sponsor
- IRCCS San Raffaele
Brain Voxel-based Morphometry in Mania
Brain Voxel-based Morphometry in Bipolar Mania
Bipolar disorder is a complex psychiatric disorder characterized by recurrent episodes of mania or hypomania and depression, and affects around one to three percent of the population .
- Trial name
- NCT03181698
- Testing
- Magnetic resonance imaging
- Where
- Egypt
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Assiut University
Cancer of Prostate, Cancer Head Neck
ARCHERY - Artificial Intelligence Based Radiotherapy Treatment Planning for Cervical, Head and Neck and Prostate Cancer
The aim of this study is to look at whether an Artificial Intelligence (AI) based computer program can automate two components of the radiotherapy treatment pathway to a sufficient quality standard to enable its routine clinical…
- Conditions
- Cancer of Prostate, Cancer Head Neck, Cancer Cervix
- Trial name
- NCT05653063
- Testing
- A web-based artificial intelligence (AI) auto-planning tool
- Where
- 6 sites in India, Jordan and 2 more
- Volunteers
- 1,029 people
- Sponsor
- University College, London
Metastasis of Unknown Origin
Role of Positron Emission Tomography in Detecting Primary Tumor in Cases of Metastases of Unknown Origin
In most cases of malignancies, the site of origin of the cancer is clear at presentation or identified soon after. However, Metastatic cancer of unknown primary site (MUO) accounts for 3-5% of all malignant neoplasms, and it is…
- Trial name
- NCT06086652
- Testing
- PET/CT
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Sohag University
Advanced Dedifferentiated Liposarcoma, Locally Advanced Dedifferentiated Liposarcoma
Testing the Addition of Cemiplimab to Palbociclib for the Treatment of Advanced Dedifferentiated Liposarcoma
This phase II trial compares the effect of treatment with palbociclib alone to treatment with palbociclib plus cemiplimab for treating patients with dedifferentiated liposarcoma that may have spread from where it first started to…
- Conditions
- Advanced Dedifferentiated Liposarcoma, Locally Advanced Dedifferentiated Liposarcoma, Metastatic Dedifferentiated Liposarcoma, Stage III Soft Tissue Sarcoma of the Trunk and Extremities AJCC v8
- Trial name
- NCT05694871
- Testing
- Palbociclib, Cemiplimab, Magnetic Resonance Imaging
- Where
- 194 sites in United States
- Volunteers
- 77 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Persistent Atrial Fibrillation, Persistent Atrial Fibrillation Longstanding
Personalized Persistent Atrial Fibrillation Ablation: The PeAF-by-LAWT Trial
The investigators hypothesized that PeAF-by-LAWT, a personalized protocol that uses a contact-force catheter, a multichannel radiofrequency (RF) generator, and integrated LAWT information to adapt the ablation index (AI) target…
- Trial name
- PeAF-by-LAWT (NCT05396534)
- Testing
- Atrial Fibrillation transcatheter ablation
- Where
- Spain
- Volunteers
- 156 people
- Sponsor
- Centro Medico Teknon
Interstitial Pulmonary Fibrosis, Emphysema
Lung Diffusing Capacities Normality Thresholds in Pulmonary Fibrosis and Emphysema
The investigators tested the usefulness of lung diffusing capacities for carbon monoxide (DLco) and nitric oxide (DLNO) normality thresholds of 5th and 2.5th percentiles for the assessment of intersitial pulmonary fibrosis (IPF)…
- Trial name
- DLNO-DLCO_emph (NCT07091838)
- Where
- Italy
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- IRCCS Azienda Ospedaliera Universitaria San Martino - IST Istituto Nazionale per la Ricerca sul Cancro, Genoa, Italy