Clinical trials: Conventional therapy, completed
Persistent Atrial Fibrillation
Randomized Evaluation of Atrial Fibrillation Treatment With Focal Impulse and Rotor Modulation Guided Procedures
The study is a prospective, multicenter, randomized study to assess the safety and effectiveness of FIRM procedures followed by conventional ablation including PVI versus a standard PVI procedure for the treatment of persistent…
- Trial name
- REAFFIRM (NCT02274857)
- Testing
- Standard PVI Ablation, FIRM-Guided Procedure and PVI
- Where
- 18 sites in United States, Germany and 1 more
- Volunteers
- 350 people
- Sponsor
- Abbott Medical Devices
Breast Cancer
Radiation Therapy (WBI Versus PBI) in Treating Women Who Have Undergone Surgery For Ductal Carcinoma In Situ or Stage I or Stage II Breast Cancer
RATIONALE: Radiation therapy uses high-energy x-rays to kill tumor cells. Giving radiation therapy in different ways may kill any tumor cells that remain after surgery.
- Trial name
- NCT00103181
- Testing
- 3-dimensional conformal accelerated partial breast irradiation, brachytherapy, whole breast irradiation
- Where
- 387 sites in United States, Canada and 2 more
- Volunteers
- 4,216 people
- Sponsor
- NSABP Foundation Inc
Gastric Cancer, Complement Component Deficiency
The Predictive Value of Complement C3 in Patients With Advanced Gastric Cancer
This study is designed to investigate whether complement C3 depletion is associated with poor short-term outcomes in postoperative patients with gastric cancer.
- Conditions
- Gastric Cancer, Complement Component Deficiency, Surgery
- Trial name
- NCT02425930
- Testing
- gastrectomy plus D2 lymphadenectomy, S-1+Oxaliplatin
- Where
- China
- Volunteers
- 85 people
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University
Infertility
Gonadotropin-releasing Hormone (GnRH) Antagonist During 3 Days
In this prospective study, the investigators would like to show whether ovarian stimulation with pretreatment of a GnRH antagonist during 3 consecutive days at initiation of the cycle, is possible.
- Trial name
- NCT01093443
- Testing
- ovarian stimulation
- Where
- Belgium
- Volunteers
- 70 people
- Sponsor
- Universitair Ziekenhuis Brussel
Epilepsy
Direct Cortical Measurement of the Intensity and Pattern of Current Flow Produced by TDCS
The primary study objective is to measure the electrical fields evoked by tDCS using subjects who have implanted intracranial electrodes as part of their evaluation for epilepsy surgery.
- Trial name
- NCT02263274
- Testing
- Transcranial Direct Current Stimulation (TDCS)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- NYU Langone Health
Colorectal Cancer, Raltitrexed
Raltitrexed in HIPEC
To evaluate the tolerance of patients with colorectal cancer to hyperthermic intraperitoneal chemotherapy with Raltitrexed, to determine the safety, tolerability, PK, and efficacy.
- Conditions
- Colorectal Cancer, Raltitrexed, HIPEC
- Trial name
- NCT04761185
- Testing
- Raltitrexed
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Fudan University
Chronic Neck Pain
Mulligan Technique for Chronic Neck Pain in Adults
This study aims to evaluate the effect of the Mulligan Technique, a manual therapy method, on reducing chronic neck pain and improving neck movement in adults aged 18 to 65 years.
- Trial name
- NCT07167108
- Testing
- Conventional program, with addition to Mulligan technique, Conventional Physical Therapy Program
- Where
- Palestinian Territories
- Volunteers
- 76 people
- Sponsor
- Prof. Mosab Saleem Hamed Amoudi
Stroke
Effectiveness of a Standardized Stroke Upper Limb Rehabilitation Program with Shortened Fugl-Meyer Assessment Stratification
The objective of the study was to investigate the effectiveness of a standardized stroke upper limb rehabilitation program with stratification using Shortened Fugl-Meyer Assessment (S-FM).
- Trial name
- NCT06902948
- Testing
- upper limb function training
- Where
- Hong Kong
- Volunteers
- 44 people
- Sponsor
- Sally Hiu Lam Wong
Colorectal Cancer
PET and CT Scans in Patients With Locally Advanced Primary Rectal Cancer That Can Be Removed During Surgery
RATIONALE: Diagnostic procedures, such as PET and CT scans, may improve the ability to detect the extent of locally advanced primary rectal cancer and may also help to measure a patient's response to treatment.
- Trial name
- NCT00004891
- Testing
- chemotherapy, computed tomography, conventional surgery
- Where
- United States
- Volunteers
- 149 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Acute Respiratory Distress Syndrome, Cardiogenic Shock
Closed Loop Mechanical Ventilation and ECMO
Mechanical ventilation and ECMO are both technologies interacting on gas exchange. Nevertheless, besides a consensus paper, no evidence-based guidelines regarding protective lung ventilation on ECMO exist to date.
- Trial name
- NCT04925518
- Testing
- Closed Loop Mechanical Ventilation, Conventional Mechanical Ventilation
- Volunteers
- 62 people
- Sponsor
- University of Zurich
CYP2C19 Polymorphism, H.Pylori Infection
Effect of the CYP2C19 Polymorphism in Helicobacter Pylori Eradication
Background: Triple therapy efficacy against Helicobacter pylori is low worldwide, thus alternatives must be sought to improve eradication. Aim: To determine CYP2C19 genetic polymorphism effect on H. pylori eradication.
- Conditions
- CYP2C19 Polymorphism, H.Pylori Infection, Therapy
- Trial name
- NCT03650543
- Testing
- amoxicillin clarithromycin omeprazole 1, amoxicillin clarithromycin omeprazole 2
- Volunteers
- 133 people, healthy volunteers welcome
- Sponsor
- Javeriana University
Surgery
Inion OTPS Biodegradable Fixation System for the Ankle
The purpose of the investigation is to compare post-operative fracture and wound healing using Inion OTPS Biodegradable Fixation System implants versus Conventional metal implants.
- Trial name
- NCT00300989
- Testing
- Inion OTPS Biodegradable Fixation System
- Where
- Finland
- Volunteers
- 43 people
- Sponsor
- Inion Oy
Radiographic Healing of Periapical Lesions Following Ultrasonic Activation of Heated Sodium Hypochlorite Without Instrumentation of Root Canals
Minimally Invasive Root Canal Treatment With Active Disinfection on Single Rooted Teeth With Periapical Lesions
A novel form of root canal treatment RCT, referred as minimally invasive endodontics MIE, has emerged recently to adopt a unique approach that emphasize reducing tooth structural changes post-treatment (32).
- Trial name
- NCT06467643
- Testing
- non-instrumented root canal treatment with passive ultrasonic activation of heated sodium hypochlorite, conventional root canal treatment with passive ultrasonic activation of heated sodium hypochlorite
- Where
- Lebanon
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Saint-Joseph University
Dental Impressions
Children's Preferences on Digital and Conventional Impression Techniques
The goal of this crossover study is to compare children's perceptions and preferences regarding digital and conventional impression techniques in the 5- to 11-year-old age group.
- Trial name
- NCT06948617
- Testing
- digital intraoral scanner, Alginate Impression
- Where
- Turkey (Türkiye)
- Volunteers
- 131 people
- Sponsor
- Uşak University
Diabetic Foot Ulcer, Diabetic Foot
Ulcer Location and Debridement Frequency: Weekly vs. Biweekly Sharp Debridement in Diabetic Foot Ulcers
The goal of this clinical trial is to determine the optimal frequency for sharp debridement in promoting the healing of diabetic foot ulcers (DFUs). The main questions it aims to answer are: 1.
- Conditions
- Diabetic Foot Ulcer, Diabetic Foot, Wound Heal
- Trial name
- NCT06160817
- Testing
- Conservative sharp debridement
- Where
- Spain
- Volunteers
- 16 people
- Sponsor
- Universidad Complutense de Madrid
Obstetric; Injury
Modified Constraint Induced Movement Therapy in Children With Obstetric Brachial Plexus Injury
The aim of this study was to increase and improve the use of affected extremity in obstetric brachial plexus palsy children while restricting the use of less affected arm and the purpose was to improve the function, Range of…
- Trial name
- NCT05411731
- Testing
- Conventional physical therapy treatment, Constraint induced movement therapy
- Where
- Pakistan
- Volunteers
- 16 people
- Sponsor
- Riphah International University
Musculoskeletal Pain, Chronic Shoulder Pain
Digital Versus Conventional Physical Therapy for Chronic Shoulder Tendinopathy
This is a single-center, prospective, randomised, controlled study, with two parallel groups, designed to assess the clinical impact of a digital exercise program against conventional rehabilitation for shoulder tendonitis.
- Conditions
- Musculoskeletal Pain, Chronic Shoulder Pain, Shoulder Tendinopathy
- Trial name
- NCT04636528
- Testing
- Digital rehabilitation, Conventional rehabilitation
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Sword Health, SA
Non-infectious Intermediate Uveitis, Non-infectious Posterior Uveitis
Safety,Tolerability and Efficacy of Intravitreal LFG316 in Patients With Active Non-infectious Intermediate-, posterior-or Panuveitis ,
This was a multi-center, randomized, active-controlled, open-label study. Approximately 24 patients with active, non-infectious intermediate-, posterior-, or panuveitis requiring systemic immunosuppressive therapy were enrolled.
- Conditions
- Non-infectious Intermediate Uveitis, Non-infectious Posterior Uveitis, Non-infectious Panuveitis
- Trial name
- NCT01526889
- Testing
- LFG316, Conventional Therapy
- Where
- 8 sites in United States, United Kingdom
- Volunteers
- 25 people
- Sponsor
- Novartis Pharmaceuticals
Perioperative Analgesia in Endometriosis
Influence of Intraoperative Nociception Guided Analgesia on Perioperative Total Analgesic Requirement Endometriosis
Adequate analgesia in the perioperative setting is one of the most important pillars of anesthesiology. It is generally understood that poorly managed acute postoperative pain correlates with increased morbidity, prolonged…
- Trial name
- ENDONOL (NCT06732050)
- Testing
- nociception guided treatment
- Where
- Switzerland
- Volunteers
- 125 people
- Sponsor
- Prof Urs Zingg
Pneumonia
Observation and Treatment of Pulmonary Microthrombosis in Childhood Pneumonia With Elevated D-dimer
Objective 1. Master the clinical feathers, imaging features and laboratory diagnosis characteristics and economic costs of children pneumonia with higher D-dimer: 1.
- Trial name
- NCT04778917
- Testing
- Low-Molecular-Weight Heparins Calcium Injection
- Where
- China
- Volunteers
- 124 people
- Sponsor
- Capital Institute of Pediatrics, China
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