Clinical trials: Conventional therapy, completed
Glioblastoma, Gliosarcoma
Temozolomide and Radiation Therapy With or Without Bevacizumab in Treating Patients With Newly Diagnosed Glioblastoma
This randomized phase III trial studies temozolomide (TMZ) and radiation therapy (RT) to compare how well they work with or without bevacizumab in treating patients with newly diagnosed glioblastoma or gliosarcoma.
- Conditions
- Glioblastoma, Gliosarcoma, Supratentorial Glioblastoma
- Trial name
- NCT00884741
- Testing
- 3-Dimensional Conformal Radiation Therapy, Bevacizumab, Intensity-Modulated Radiation Therapy
- Where
- 330 sites in United States, Canada and 1 more
- Volunteers
- 637 people
- Sponsor
- National Cancer Institute (NCI)
Haemodynamic Instability
Transcapillary Plasma Refill in Advanced Chronic Kidney Disease
Background: Haemodynamic instability during haemodialysis has long been linked to poor cardiovascular outcomes. It does not always reflect overall hydration but rather plasma volume depletion, with a delay in plasma refill from…
- Trial name
- PRUf (NCT03348488)
- Testing
- Ultrafiltration dose
- Where
- United Kingdom
- Volunteers
- 24 people
- Sponsor
- Manchester University NHS Foundation Trust
Acute Respiratory Distress Syndrome, Intensive Care Unit
The Effect of Preemptive APRV on Patients With High Risk for ARDS
Airway pressure release ventilation (APRV) is a mode of mechanical ventilation that alternates between two levels of continuous positive airway pressure (CPAP) support and allows spontaneous respiratory effort at either CPAP…
- Trial name
- NCT04699513
- Testing
- Mechanical Ventilation Mode (airway pressure release ventilation )
- Volunteers
- 65 people
- Sponsor
- Karadeniz Technical University
Stroke
The Effects of Thoracic Joint Mobilization on Pulmonary Functions of Patients With Stroke
Stroke a neurological disorder leads to long term disability and decline in overall quality of life. Pulmonary Functions are usually impaired in individuals with stroke.
- Trial name
- NCT04188496
- Testing
- Pulmonary Function Test group, Control Group
- Where
- Pakistan
- Volunteers
- 26 people
- Sponsor
- Shehla Gul
Chronic Obstructive Pulmonary Disease
The Effect of Reflective Breathing Therapy Compared With Conventional Breathing Therapy in Patients With Chronic Obstructive Pulmonary Disease (COPD) III-IV
The purpose of this study is to determine whether different types of breathing therapies in patients with COPD III-IV decrease dyspnea and increase activity.
- Trial name
- NCT01478646
- Testing
- conventional breathing therapy, reflectory breathing therapy
- Where
- Germany
- Volunteers
- 24 people
- Sponsor
- Schön Klinik Berchtesgadener Land
Neoplasms, Head and Neck
Lapatinib Versus Placebo Given Concurrently With Cisplatin And Radiotherapy In Patients With Unresected Head And Neck Cancer
This is a phase II study comparing the effects of lapatinib versus placebo when administered concurrently with cisplatin and radiotherapy followed by 1 year monotherapy with lapatinib or placebo.
- Trial name
- NCT00387127
- Testing
- Lapatinib oral tablets, radiotherapy, cisplatin chemotherapy
- Where
- 30 sites in United States, Canada and 7 more
- Volunteers
- 67 people
- Sponsor
- GlaxoSmithKline
Knee Osteoarthritis
Effects of Kinesio-taping in Knee Osteoarthritis Patients.
The main reason to conduct this research is to find the comparison of kinseotaping according to time duration that is 24 hours, 48 hours and 72 hours in knee osteoarthritis patients.
- Trial name
- NCT04585373
- Testing
- kinesio-taping with conventional therapy 24 hours, kinesio-taping with conventional therapy 48 hours, kinesio-taping with conventional therapy 72 hours
- Where
- Pakistan
- Volunteers
- 48 people
- Sponsor
- Riphah International University
Myopia ≤ -6 Diopters or Myopic Astigmatism ≤ -4 Diopters
Outcomes of a New Trans-epithelial Photorefractive Keratectomy (Streamlight PRK) Compared to Conventional PRK Procedures
Photorefractive keratectomy (PRK) involves mechanical or alcohol assisted debridement of the epithelium that leads to potential basement membrane (BM) injury ,with resultant more significant haze and pain compared to laser…
- Trial name
- NCT04710082
- Testing
- Photorefractive keratectomy (PRK)
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Assiut University
Cystic Fibrosis, Lung Infection Bacterial
Clinical Performance of the AtbFinder® Test System for Selection of Antibiotic Therapy in Persons With Cystic Fibrosis
This prospective case-control study was planned to evaluate the efficacy of antibiotic therapy selected with the AtbFinder® in persons with cystic fibrosis.
- Trial name
- NCT05584982
- Testing
- AtbFinder
- Volunteers
- 35 people
- Sponsor
- TGV-Dx
Neonatal Sepsis
Effects of Melatonin as a Novel Antioxidant and Free Radicals Scavenger in Neonatal Sepsis
Assess the efficacy of melatonin as an adjuvant in the treatment of free radical disease in septic preterms receiving melatonin compared to those on conventional treatment through measuring the level of Malondialdehyde as a…
- Trial name
- NCT03295162
- Testing
- Melatonin 10 mg, Conventional treatment of neonatal sepsis
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Mohamed Hussein Metwally
Response Assessment in Newly Diagnosed RA Patients at 3rd Month Was Evaluated by DAS28 and ACR in Relation to JAK Expression
JAK2 Mutation May Predict Response and Guide First Line Treatment in Rheumatoid Arthritis
This study included 76 newly diagnosed RA patients and 50 matched controls. Basal JAK2 mutation was assessed by PCR in blood samples, TNF-α and IL 6 were measured by ELISA in serum of patients and controls.
- Trial name
- NCT04667988
- Testing
- JAK expression
- Where
- Egypt
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Impingement Syndrome, Impingement Shoulder
PMT Versus IASTM in Subacromial Impingement Syndrome
This assessor-blinded, three-arm, parallel-group randomized controlled trial will investigate the additional effects of percussion massage therapy and instrument-assisted soft tissue mobilization in individuals with subacromial…
- Conditions
- Impingement Syndrome, Impingement Shoulder, Shoulder Pain
- Trial name
- NCT07756203
- Testing
- Percussion massage therapy device, Instrument-assisted soft tissue mobilization device, Conventional Physiotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Emre DANSUK
Lateral Medullary Syndrome, Deglutition Disorders
The Motor Imagery Based on Action Observation Treatment on Dysphagia in Wallenberg Syndrome
The goal of this clinical trial is to learn about on dysphagia in wallenberg syndrome. The main questions it aims to answer are: the efficacy of motor imagery based on action observation treatment in the rehabilitation of…
- Trial name
- NCT06224686
- Testing
- conventional dysphagia treatment, motor imagery based on action observation treatment
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Le Wang
Asthma
The Use of Inflammatory Markers to Guide Therapy in Children With Severe Asthma
The purpose of this study is to determine whether using non-invasive measurements of airway inflammation can improve clinical decision making in children with severe asthma compared to conventional management (British Thoracic…
- Trial name
- NCT00262340
- Testing
- Non invasive measurement of airway inflammation
- Where
- United Kingdom
- Volunteers
- 55 people
- Sponsor
- Royal Brompton & Harefield NHS Foundation Trust
Shoulder Pain, Balance; Distorted
Investigation of the Effect of Conventional Treatment on Postural Stability and Balance in Individuals With Shoulder Pain
Shoulder pain is one of the most common musculoskeletal complaints that people need treatment for. Typical signs and symptoms include pain during reaching, muscle weakness, and interrupted sleep.
- Trial name
- NCT05444426
- Testing
- Shoulder Rehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Istanbul University - Cerrahpasa
Stroke
Is Robot-Assisted Therapy Effective for the Upper Extremity Following a Stroke
The aim of this study was to investigate the effects on upper-limb motor function of the addition of robotic rehabilitation (RR) and conventional rehabilitation (CR) treatments to intensive trunk rehabilitation (ITR).
- Trial name
- NCT05559385
- Testing
- Robot-Assissted Therapy, Conventional Rehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 41 people
- Sponsor
- Emresenocak
Extensive Stage Small Cell Lung Cancer
The Addition of Ipilimumab to Carboplatin and Etoposide Chemotherapy for Extensive Stage Small Cell Lung Cancer
This trial will investigate the addition of an antibody (Ipilimumab) to conventional Carboplatin and Etoposide chemotherapy in extensive stage small cell lung cancer.
- Trial name
- ICE (NCT01331525)
- Testing
- Ipilimumab
- Where
- 7 sites in United Kingdom
- Volunteers
- 42 people
- Sponsor
- University Hospital Southampton NHS Foundation Trust
Pulmonary Disease
High Flow vs Conventional Oxygen in Head and Neck Surgery
Patients undergoing major head and neck surgery are at risk for postoperative pulmonary complications. The goal of this randomized clinical trial is to evaluate the effectiveness of high flow heated humidified oxygen at…
- Trial name
- NCT05362526
- Testing
- High flow humidification, Conventional cool mist aerosol humidification
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- University of Florida
Gestational Diabetes Mellitus in Pregnancy
Carbohydrates Distribution in Pregnancy Study
Hypothesis: Patients with Gestational Diabetes Mellitus (GDM) have a high risk to develop complications during pregnancy, puerperium and in the newborn.
- Trial name
- CHiPS (NCT03378908)
- Testing
- Intervention Treatment
- Where
- 2 sites in Spain
- Volunteers
- 10 people
- Sponsor
- Germans Trias i Pujol Hospital
Cerebral Palsy
Comparision Of The Effectiveness Of Physiotherapy Methods
A total of 28 patients who were followed-up in our clinic and received botulinum toxin injection of lower extremities in the last month were randomized to two groups in the study.
- Trial name
- NCT04328168
- Testing
- ROM exercises, stretching, positioning, gait training, by two physiotherapist under the supervision of a doctor
- Volunteers
- 28 people
- Sponsor
- Kayseri Education and Research Hospital
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