Clinical trials: Conventional therapy
Non-Alcoholic Fatty Liver Disease, Obesity, Morbid
Change of Adipose Tissues and Triglyceride After Bariatric Surgery or Life-style Intervention
The study is aimed To quantify the change of adipose tissues, triglyceride in liver and pancreas and cholesterol after lifestyle intervention or bariatric surgery.
- Conditions
- Non-Alcoholic Fatty Liver Disease, Obesity, Morbid, Brown Fat, Metabolic Disease
- Trial name
- NCT03875625
- Testing
- Bariatric surgery, Dietitian led life style modification intervention, Conventional care (control)
- Where
- Hong Kong
- Volunteers
- 80 people
- Sponsor
- Chinese University of Hong Kong
Cervical Disc Herniation
Efficacy of High-intensity Laser Therapy (HILT) in the Patients With Cervical Disc Herniation
The worldwide prevalence of neck pain is between 16.7-75.1%, it has been seen at an increasing rate in recent years due to sedentary living conditions.
- Trial name
- NCT05474625
- Testing
- High Intensity Laser Therapy, Ultrasound, Transcutaneous nerve stimulation (TENS)
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Baskent University Ankara Hospital
Frozen Shoulder, Adhesive Capsulitis
Spencer's Technique Versus Mulligan's Technique for Stage II Frozen Shoulder
Stage II frozen shoulder (adhesive capsulitis) is associated with pain, stiffness, restricted shoulder range of motion, and reduced quality of life.
- Trial name
- NCT07844135
- Testing
- Spencer's Muscle Energy Technique With Conventional Physiotherapy, Mulligan's Mobilization With Movement With Conventional Physiotherapy
- Where
- 2 sites in Pakistan
- Volunteers
- 72 people
- Sponsor
- Superior University
Hyperkalemia
Lower vs. Standard Insulin-Dextrose Doses for Treating Mild to Moderate Hyperkalemia in the Emergency Department
This clinical trial aims to evaluate the safety and efficacy of a lower dose insulin compared to the conventional dose for treating mild to moderate hyperkalemia, a condition characterized by elevated serum potassium levels below…
- Trial name
- IDK+ (NCT06724991)
- Testing
- Lower Dose Therapy, Conventional Dose Therapy
- Where
- Malaysia
- Volunteers
- 50 people
- Sponsor
- University of Malaya
Acquired Bleeding Disorder, Cardiac Surgery Requiring Cardiopulmonary Bypass
Activated Recombinant Human Factor VII Following Cardiac Bypass Surgery for Paediatric Congenital Heart Disease
This trial is conducted in Oceania. The aim of this trial is to investigate the efficacy of activated recombinant human factor VII and standard treatment compared with standard haemostatic replacement therapy in cardiopulmonary…
- Trial name
- NCT01562574
- Testing
- activated recombinant human factor VII
- Where
- Australia
- Volunteers
- 82 people
- Sponsor
- Novo Nordisk A/S
Brachial Plexus Birth Palsy, Physical Therapy
Virtual Reality and Dual-Task Training for Cortical Plasticity in Children With Brachial Plexus Injury
Brachial plexus birth injury (BPBI) is a condition that occurs when the nerves controlling the arm are injured during birth, leading to weakness, limited movement, and sensory problems.
- Trial name
- NCT07291310
- Testing
- Conventional Physiotherapy Program, Virtual Reality, Dual Task
- Where
- Turkey (Türkiye)
- Volunteers
- 14 people
- Sponsor
- Istanbul Aydın University
COVID-19
Phase 1 Study on Bioavailability, Food Effect, and Drug-Drug Interaction of ALG-097558 Tablets in Healthy Volunteers
The aim of this multi-part Phase 1 study is to evaluate the drug-drug interaction (DDI) potential of ALG-097558 via co-administration with a P-gp substrate (dabigatran) and a CYP3A4 inhibitor/P-gp inhibitor (itraconazole).
- Trial name
- NCT06945276
- Testing
- ALG-097558, Dabigatran, Itraconazole
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Stable Angina
Aspirin Resistance and Percutaneous Coronary Intervention (PCI)
The objective of this study is to evaluate if aggressive antiplatelet therapy would reduce ischemic events in aspirin (ASA) resistant patients after percutaneous coronary intervention (PCI).
- Trial name
- RESIST (NCT01103440)
- Testing
- Intravenous Glycoprotein inhibitor + ASA, Clopidogrel, Antiplatelet Therapy (ASA, Clopidogrel)
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Nasopharyngeal Carcinoma
BGT007 Cell Treatment of Nasopharyngeal Carcinoma
This is an exploratory study to evaluate the safety and preliminary effectiveness of BGT007 cells in the treatment of recurrent/metastatic nasopharyngeal carcinoma
- Trial name
- NCT05616468
- Testing
- BGT007 Cell Injection, Fludarabine, cyclophosphamide
- Where
- China
- Volunteers
- 23 people
- Sponsor
- The Affiliated Hospital of Xuzhou Medical University
Symptomatic Irreversible Pulpitis (SIP), Post Operative Pain After Root Canal Therapy
Effects of Irrigation Activation and Obturation Techniques on Pain After Root Canal Treatment
This randomized controlled clinical trial aimed to compare postoperative pain and analgesic use following single-visit root canal treatment performed using different final irrigation activation and root canal obturation…
- Trial name
- NCT07882368
- Testing
- Conventional Needle Irrigation, Sonic Irrigation Activation, Cold Lateral Condensation
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Biruni University
Rare Tumour
Study of Precision Treatment for Rare Tumours in China Guided by PDO and NGS
The objective of this Phase II, open-label, multicenter, non-randomised controlled clinical trial is to guide precision treatment for patients with rare tumours based on Patient-Derived Organoids/Next-Generation Sequencing drug…
- Trial name
- SPRING (NCT06692491)
- Testing
- Albumin-Bound Paclitaxel, Epirubicin, Gemcitabine
- Volunteers
- 200 people
- Sponsor
- Peking University Shenzhen Hospital
Adhesive Capsulitis
Spencer's Muscle Energy Technique Along With Strain Counter Strain in Adhesive Capsulitis.
Numerous Physiotherapy techniques have been found to be beneficial but there is no consensus on the best treatment approach for speeding up rehabilitation process and rejuvenating functional capacity in patients suffering from…
- Trial name
- NCT04822324
- Testing
- Spencer Muscle energy technique with conventional Physiotherapy, Strain counter strain along with conventional Physiotherapy and Spencer Muscle energy technique
- Where
- Pakistan
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Urinary Incontinence
Tele-rehabilitation for Women With Urinary Incontinence
The prevalence of urinary incontinence (UI) in the female Greek population is 1 to 3 women (27%).Globally, the development of tele-rehabilitation programs through mobile application (mobile apps) has been a breakthrough for UI…
- Trial name
- NCT06161324
- Testing
- PFM exercises program through the Mobile app in cooperation with the superficial sensor, Face-to face PFM exercises program in Healthcare environment, PFM exercises program via home-leaflet(without suprevision)
- Where
- Greece
- Volunteers
- 60 people
- Sponsor
- University of Patras
Goal-directed Fluid Therapy
Stroke Volume Variation- Guided Hemodynamic Therapy Versus Oxygen Extraction Ratio-guided Hemodynamic Therapy
The FloTrac/Vigileo is a minimal invasive device assessing flow based hemodynamic parameters by pulse contour analysis based on the radial artery pressure signal.
- Trial name
- NCT05487924
- Testing
- SVV-GDHT, O2ER-GDHT, conventional care
- Volunteers
- 610 people
- Sponsor
- Beijing Tongren Hospital
Cerebral Palsy
Development of Kinect-assisted Home-based Bilateral Arm Training Program for Cerebral Palsy
The purpose of the present study is to develop a long term cost-effectiveness (efficient protocol, playful context, and practical strategy) training program for school-age children with Cerebral Palsy.
- Trial name
- NCT02801279
- Testing
- Conventional bilateral arm training, Kinect-based bilateral arm training
- Where
- Taiwan
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Urinary Tract Infections-UTI
Conventional and Molecular Diagnostic Method for Patients With Suspected UTI
In this protocol, the investigators are examining the use of a novel pathogen testing technology and method of identification of antibiotic susceptibility against the conventional C \& S testing for patients with both complicated…
- Trial name
- NCT02623179
- Testing
- culture versus Molecular diagnostics
- Volunteers
- 50 people
- Sponsor
- Southwest Regional PCR, LLC
Stroke, Unilateral Spatial Neglect
Therapeutic Serious Game and Rehabilitation of Stroke Patient
The growing field of new technologies offers new perspectives for neurorehabilitation. Serious games are a promising solution in the rehabilitation of cognitive impairments, and they may be useful in the rehabilitation of…
- Trial name
- NCT05661396
- Testing
- Serious game rehabilitation
- Volunteers
- 6 people
- Sponsor
- Hopitaux de Saint-Maurice
Cerebral Palsy Spastic Diplegia
Effect of Botulinum Toxin on Selective Motor Control and Pain in Diplegic Cerebral Palsy
The aim of this study is to investigate the effects of Botulinum Neurotoxin-A (BoNT-A) injection applied to spastic muscles on pain sensation and Selective Motor Control (SMC) in cases diagnosed with diplegic spastic Cerebral…
- Trial name
- NCT06583343
- Testing
- OnabotulinumtoxinA, Conventional Physical Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Mycoses
Therapeutic Drug Monitoring of Voriconazole
The purpose of this study is to determine whether therapeutic drug monitoring of voriconazole is useful in the treatment of invasive fungal infection.
- Trial name
- NCT00890708
- Testing
- Voriconazole (therapeutic drug monitoring)
- Where
- South Korea
- Volunteers
- 110 people
- Sponsor
- Seoul National University Hospital
Breast Cancer
Effect of Mechanical Stimulation on Mastectomy Scars
The purpose of this study is to investigate the efficacy of mechanical stimulation on mastectomy scars in: (i) alleviating scar appearance - pigmentation, vascularity, pliability and thickness, (ii) reducing shoulder morbidities…
- Trial name
- NCT02702050
- Testing
- Mechanical stimulation (LPG system; Cellu M6 Integral I), Conventional treatment
- Where
- Hong Kong
- Volunteers
- 108 people
- Sponsor
- The Queen Elizabeth Hospital
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