Clinical trials: Conventional therapy
Liver, Cancer of, Primary Resectable
Applicability of 3D-HDRA in Patients With Primary Liver Cancer: A Randomized Controlled Trial
This Randomized Controlled Trial was to clarity the clinical feasibility of 3D-HDRA results in guiding the drug use of interventional chemotherapy after primary liver cancer surgery.
- Trial name
- NCT05701436
- Testing
- Oxaliplatin, Doxorubicin, Lobaplatin
- Where
- China
- Volunteers
- 144 people
- Sponsor
- Zhujiang Hospital
Candida Sepsis, Candidiasis, Invasive
Early Identification of Candida in Intra-abdominal Candidiasis
Intra-abdominal candidiasis remains the first origin of invasive candidiasis in critically ill patients with a mortality up to 60%. This high mortality is partly related to delay of anti-fungal treatment administration.
- Conditions
- Candida Sepsis, Candidiasis, Invasive, Peritonitis Infectious, Critically Ill
- Trial name
- ICCA (NCT05264571)
- Testing
- calscreener, Metabolic profile, optical microscopy
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Central Hospital, Nancy, France
Lower Extremity Ischemia
CRAIL - Controlled Reperfusion of the Acutely Ischemic Limb
The purpose of this study is to prove the findings of a preliminary study which strongly suggest the hypothesis that the result of conventional embolectomy for acute, severe lower-limb ischemia can be improved by controlled…
- Trial name
- CRAIL (NCT00567801)
- Testing
- conventional embolectomy/thrombectomy, embolectomy/thrombectomy with controlled reperfusion
- Where
- 23 sites in Austria, Germany
- Volunteers
- 250 people
- Sponsor
- University Hospital Freiburg
Spastic Cerebral Palsy
Effects of Pediatric Aquatic Therapy in Children With Spastic Cerebral Palsy
Aquatic intervention had been applied in children with neuromotor impairment for years, yet there has been little progress toward objective identifications of therapy goals, interventions, and outcomes.
- Trial name
- NCT01049581
- Testing
- aquatic therapy
- Where
- Taiwan
- Volunteers
- 27 people
- Sponsor
- Chang Gung Memorial Hospital
Epiphora, Dacryocystorhinostomy
SLlt Stent II Lacrimal Stent for the Treatment of Nasolacrimal Duct Obstruction
This project aims to test whether a newly designed lacrimal stent - the SlitStent - when placed into the lacrimal system in the standard fashion following a DCR surgery, will provide good symptomatic relief for epiphora and be…
- Trial name
- SLINDO (NCT03705000)
- Testing
- Slit Stent II, BIKA for DCR
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Thomas Gardner
Hemodialysis Access Failure
Effectiveness of Endoluminal Treatment of Autologous Arteriovenous Endovascular Fistula Failure
This study was aimed at comparing the efficacy and safety of cutting balloons versus drug-coated balloons in treating venous segment stenosis of autologous arteriovenous fistulas.This is a prospective, multi-center cohort study.
- Trial name
- NCT06493292
- Testing
- Endovascular therapy
- Where
- 3 sites in China
- Volunteers
- 180 people
- Sponsor
- RenJi Hospital
Purpura, Thrombocytopenic, Idiopathic
High-dose Dexamethasone Versus Conventional Dose Prednisone for Initial Treatment of Primary Immune Thrombocytopenia (ITP)
The project was undertaking by Qilu Hospital of Shandong University and other 11 well-known hospitals in China. In order to report the efficacy and safety of high-dose dexamethasone compared to conventional dose prednisone for…
- Trial name
- NCT01356511
- Testing
- Prednisone, Dexamethasone
- Where
- China
- Volunteers
- 261 people
- Sponsor
- Shandong University
Herpes Zoster, Pain
The Analgesic Efficacy and Safety of Baclofen in Patients With Herpes Zoster
Herpes zoster (HZ) is characterized by a painful dermatomal rash and significantly affects quality of life, with acute pain increasing the risk of postherpetic neuralgia.
- Trial name
- NCT07378046
- Testing
- Baclofen combined conventional therapy, Conventional therapy
- Where
- China
- Volunteers
- 750 people
- Sponsor
- Beijing Tiantan Hospital
Meniscus Lesion
Comparison of the Effectiveness of Single and Dual Task Training Applied to Individuals With Knee Meniscus Lesion
The main function of the meniscus is to transfer and distribute femoral pressure to the tibia. Treatment of meniscus tears is divided into conservative and surgical treatment.
- Trial name
- NCT06886542
- Testing
- Dual task training, Single task training, Conventional physiotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Ankara Yildirim Beyazıt University
Low Back Pain, Rehabilitation
The Effects of Dynamic Neuromuscular Stabilization Approach
When the positive effects of the recently popular "Dynamic Neuromuscular Stabilization (DNS)" approach are examined, it suggests that it may be a possible treatment option in geriatric individuals with chronic nonspecific low…
- Conditions
- Low Back Pain, Rehabilitation, Treatment
- Trial name
- NCT04948073
- Testing
- Dynamic neuromuscular stabilization approach, Conventional treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Hacettepe University
Transcranial Magnetic Stimulation, Freezing of Gait
Dual-target, High-dose TMS for PD Patients With FOG
The aim of the current study was to verify whether high-dose TMS treatment of the motor and cognitive cortices is more effective in alleviating FOG than conventional-dose TMS of the motor cortex only.
- Trial name
- NCT05625386
- Testing
- transcranial magnetic stimulation
- Where
- China
- Volunteers
- 64 people
- Sponsor
- Anhui Medical University
Open Fractures, Degenerative Osteoarthritis and Degenerative Spinal Diseases
A Prospective Randomized Controlled Study on the Clinical Efficacy of a New Surface Modified Composite Coating Orthopedic Implant Device
This study is a prospective, randomized, controlled, double-arm, non-inferiority study that will be carried out in China. It aims to compare two implant systems (the research group uses surface-modified composite coated…
- Trial name
- NCT04481269
- Testing
- Surface-modified composite coated orthopedic implants, conventional orthopedic implants
- Volunteers
- 240 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Prostate Carcinoma, Prostate Small Cell Neuroendocrine Carcinoma
Autologous T Cells Lentivirally Transduced to Express L1CAM-Specific Chimeric Antigen Receptors in Treating Patients With Locally Advanced and Unresectable or Metastatic Small Cell Neuroendocrine Prostate Cancer
This phase I trial studies the side effects and best dose of autologous CD8+ and CD4+ lentivirally transduced to express L1CAM-specific chimeric antigen receptor (CAR) and EGFRt mutation specific T cells and to see how well they…
- Conditions
- Prostate Carcinoma, Prostate Small Cell Neuroendocrine Carcinoma, Stage III Prostate Cancer AJCC v8, Stage IV Prostate Cancer AJCC v8
- Trial name
- NCT06094842
- Testing
- Bendamustine, Biopsy, Biospecimen Collection
- Where
- United States
- Sponsor
- Fred Hutchinson Cancer Center
Hodgkin Lymphoma
A Study of Brentuximab Vedotin With Doxorubicin, Vinblastine and Dacarbazine in Adults With Hodgkin Lymphoma in India
The main aim of this study is to check how safe brentuximab vedotin is in adults with untreated Hodgkin Lymphoma (HL) when given together with doxorubicin (Adriamycin), vinblastine and dacarbazine therapy ('AVD').
- Trial name
- NCT06831370
- Testing
- Brentuximab Vedotin, Doxorubicin, Vinblastine
- Where
- 11 sites in India
- Volunteers
- 124 people
- Sponsor
- Takeda
Grade-II Cervical Spondylosis
Effects of Clinical Based Versus Synchronized Telerehabilitation on Pain, Exercise Adherence, and Functional Disability Among Patients With Grade-II Cervical Spondylosis.
This randomized controlled trial aims to compare the effects of clinical-based rehabilitation and synchronized telerehabilitation on pain, exercise adherence, and functional disability in patients with Grade-II cervical…
- Trial name
- NCT07679373
- Testing
- Group A: Clinical Based Rehabilitation, Group B: Synchronized Telerehabilitation
- Where
- Pakistan
- Volunteers
- 52 people
- Sponsor
- Lahore University of Biological and Applied Sciences
Patellofemoral Pain Syndrome
Effect of Adding Inguinal Ligament Mobilization to Talonavicular Joint Mobilization on Patellofemoral Pain Syndrome
This study will be conducted to: To assess the effect of adding the inguinal ligament mobilization to talonavicular joint mobilization on pain intensity subjects with PFPS To assess the effect of adding the inguinal ligament…
- Trial name
- NCT07734051
- Testing
- inguinal ligament mobilization or talonavicular joint mobilization or both inguinal and talonavicular joint mobilizations or conventional physical therapy exercises
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Cairo University
Dementia
Occupational Therapy Programme of Patients With Dementia Performing Activities of Daily Living
To assess the effectiveness of the Stimulation of Activities of Daily Living (SADL) Occupational Therapy programme on the independence of ADL by persons with dementia who are institutionalized.
- Trial name
- OTSALD (NCT02199353)
- Testing
- Stimulation of Activities Daily Living, Conventional ADLOccupational Therapy
- Where
- Spain
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University of Extremadura
Stroke
Xbox Kinect Training on Upper Limb Motor Function in Stroke Patients
.To determine the effects of Xbox Kinect training on upper limb motor function with conventional physical therapy in stroke patients
- Trial name
- NCT04669431
- Testing
- Xbox kinect Training, Conservative Rehabilitation
- Where
- Pakistan
- Volunteers
- 58 people
- Sponsor
- Riphah International University
Adult Malignant Fibrous Histiocytoma of Bone, Desmoid Tumor
Sunitinib in Treating Patients With Metastatic, Locally Advanced, or Locally Recurrent Sarcomas
RATIONALE: Sunitinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth and by blocking blood flow to the tumor.
- Conditions
- Adult Malignant Fibrous Histiocytoma of Bone, Desmoid Tumor, Endometrial Cancer, Ovarian Cancer
- Trial name
- NCT00474994
- Testing
- sunitinib malate
- Where
- 2 sites in United States
- Volunteers
- 53 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Oropharyngeal Carcinoma, De-escalation
De-escalation Protocols in HPV-related Oropharyngeal Carcinoma in Chinese Populations
Human papillomavirus (HPV)-related oropharyngeal carcinoma are exquisitely radiosensitive. Several studies attempted to reduce the toxicities of treatments through reduced-dose radiation and showed promising results, but all data…
- Trial name
- NCT04012502
- Testing
- Toxicities reduced treatment, conventional treatment
- Where
- China
- Volunteers
- 83 people
- Sponsor
- Fudan University
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