Clinical trials: Conventional therapy
Lung Cancer
Positron Emission Tomography in Predicting Response in Patients Who Are Undergoing Treatment With Pemetrexed Disodium and Cisplatin With or Without Surgery for Stage I, Stage II, or Stage III Non-Small Cell Lung Cancer
RATIONALE: Diagnostic procedures, such as positron emission tomography (PET), (done before, during, and after chemotherapy) may help doctors predict a patient's response to treatment and help plan the best treatment.
- Trial name
- NCT00227539
- Testing
- cisplatin, pemetrexed disodium, adjuvant therapy
- Where
- 2 sites in United States
- Volunteers
- 25 people
- Sponsor
- University of Washington
Healthy
Resistance Training With Blood Flow Restriction
Blood flow restriction associated with resistance training is suggested to potentiate increases in muscular strength and hypertrophy.
- Trial name
- NCT05863039
- Testing
- Blood flow restriction, Regular training type 1, Regular training type 2
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Breast Cancer, HER2-negative Breast Cancer
Carboplatin+Nab-paclitaxel, Plus Trastuzumab (HER2+) or Bevacizumab (HER2-) in the Neoadjuvant Setting
This phase II is studying the side effects and how well carboplatin and paclitaxel albumin-stabilized nanoparticle formulation when together with bevacizumab or trastuzumab before surgery works in treating patients with stage…
- Conditions
- Breast Cancer, HER2-negative Breast Cancer, HER2-positive Breast Cancer, Recurrent Breast Cancer
- Trial name
- NCT00618657
- Testing
- Carboplatin, paclitaxel albumin-stabilized nanoparticle formulation, bevacizumab
- Where
- United States
- Volunteers
- 127 people
- Sponsor
- University of California, Irvine
Sleep Apnea, Dyslipidaemia
Effect of Nasal CPAP on Lipid Profile in Patients With Dyslipidaemia and Sleep Apnea
OBJECTIVES Main objective: To assess if six months of treatment with CPAP, associated with conventional treatment, improves the lipid profile of patients with dyslipidemia and mild-moderate apnea-hypopnea syndrome (OSA).
- Trial name
- NCT02557412
- Testing
- Continuous positive airway pressure, Intensive lifestyle intervention, Conventional treatment
- Where
- Spain
- Sponsor
- Hospital Universitario La Paz
Liver Transplant Disorder, Sleep
The Effect Of Therapeutic Touch and Music Rest on Sleeping Applied to Children With Liver Transplantation
Today, the demand for liver transplantation is increasing day by day, since liver transplantation is considered the most effective treatment for end-stage liver disease.
- Trial name
- NCT05108636
- Testing
- Therapeutic Touch, Music Rest
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Maksude YILDIRIM
Stroke, Hemiplegia
Asymmetrical Gait Training After Pediatric Stroke
The purposes of this pilot research study are 1. To begin to test if two different types of physical therapy might have different results in children and adolescents who have had a prior stroke, and 2.
- Trial name
- NCT01827436
- Testing
- Conventional physical therapy, Asymmetrical gait training
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Children's Hospital of Philadelphia
Head and Neck Cancer, Radiation Toxicity
Parotid-Sparing Intensity-Modulated Radiation Therapy Compared With Conventional Radiation Therapy in Treating Patients With Oropharyngeal or Hypopharyngeal Cancer Who Are at High Risk of Radiation-Induced Xerostomia
RATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells. Intensity-modulated radiation therapy delivers thin beams of radiation of different strengths directly to the tumor from many angles.
- Conditions
- Head and Neck Cancer, Radiation Toxicity, Xerostomia
- Trial name
- NCT00081029
- Testing
- management of therapy complications, radiation therapy
- Where
- 9 sites in United Kingdom
- Volunteers
- 84 people
- Sponsor
- Royal Marsden NHS Foundation Trust
Consciousness Disorder
Multimodal Neuroprognostication in Disorders of Consciousness
Disorders of consciousness frequently occur at the acute phase of brain injuries. For the most severe cases, consciousness impairment can be prolonged.
- Trial name
- M-Neuro-DoC (NCT04534777)
- Testing
- repeated neurological, behavioral assessments and conventional, quantitative and functional brain imagery
- Where
- France
- Volunteers
- 500 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Irritable Colon, Irritable Bowel Syndrome (IBS)
Study In Women With Severe Diarrhea-Predominant Irritable Bowel Syndrome Having Failed Conventional Therapy
The purpose of this study is to compare the safety and effectiveness of as needed versus fixed dosing of an investigational medication for women with severe diarrhea-predominant Irritable Bowel Syndrome (IBS) who have failed…
- Trial name
- NCT00067457
- Testing
- alosetron
- Where
- 191 sites in United States, Australia
- Volunteers
- 700 people
- Sponsor
- GlaxoSmithKline
Whiplash Injuries
Efficacy of the Use of Dry Needling in Conventional Non-invasive Treatment of Acute and Subacute Whiplash
INTRODUCTION: Whiplash is an injury produced by an acceleration-deceleration mechanism that transmits energy to the cervical spine.
- Trial name
- NCT03502928
- Testing
- Motor Control, Manual Therapy, Dry Needling
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- University of Alcala
Multivessel Coronary Artery Disease
The Catholic University BIMA Grafting Study
The present study hypothesizes that the systematic use of bilateral internal mammary artery (BIMA) grafting is feasible in the practice of a University Cardiac Surgery Institution for the treatment of multivessel coronary artery…
- Trial name
- CATHEXIS (NCT01593865)
- Testing
- BIMA Grafting, Left-only mammary artery grafting
- Where
- Italy
- Volunteers
- 1,000 people
- Sponsor
- Catholic University, Italy
Convulsion, Non-Epileptic
Treatment Outcomes of ReACT for PNES
This research study is examining the effects of Retraining and Control Therapy (ReACT; an intervention focused on changing behaviors and thoughts) for psychogenic non-epileptic seizures (PNES, episodes resembling epileptic…
- Trial name
- NCT02801136
- Testing
- ReACT, Supportive Therapy
- Where
- United States
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Stroke
Effects of Inspiratory Muscle Training on Stroke Rehabilitation Outcomes
This study is designed to explore the effects of a 4-week protocol of inspiratory muscle training (IMT) at 50% maximum inspiratory pressure (MIP) on respiratory function, diaphragm thickness, balance control, exercise capacity…
- Trial name
- NCT06640101
- Testing
- IMT-stable group (sitting on a stable surface), IMT-unstable group (sitting on an unstable surface), Conventional treatment
- Where
- China
- Volunteers
- 84 people
- Sponsor
- Hong Kong Metropolitan University
Subacromial Impingement
EFFICACY OF ADDING TRUNK INTEGRATED KINETIC CHAIN EXERCISES TO CONVENTIONAL EXERCISE THERAPY PROGRAM IN SUBACROMIAL IMPINGEMENT SYNDROME
The purpose of this study will be to investigate the effect of adding trunk integrated kinetic chain exercises to conventional exercise program on shoulder pain, function, isometric muscle strength, shoulder ROM and scapular…
- Trial name
- NCT06926465
- Testing
- Conventional treatment, Trunk integrated kinetic chain exercises
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Cairo University
Myocardial Reperfusion, Myocardial Infarction
Effects of Postconditioning On Myocardial Reperfusion
The purpose of this study is to investigate the effects of postconditioning on myocardial reperfusion in patients with ST-segment elevation myocardial infarction.
- Trial name
- POST (NCT00942500)
- Testing
- Post-conditioning
- Where
- South Korea
- Volunteers
- 700 people
- Sponsor
- Samsung Medical Center
Peripheral Arterial Disease, Diabetic Angiopathies
Evaluating Bu Yang Huanwu Decoction For Early Diabetic Vascular Disease
The goal of this clinical trial is to learn if adding a Traditional Chinese Medicine formula, Bu Yang Huanwu Decoction (specifically the capsule form called Hua Yu Wan Capsule), to standard treatment can help prevent leg pain at…
- Conditions
- Peripheral Arterial Disease, Diabetic Angiopathies, Arterial Occlusive Diseases
- Trial name
- NCT07658807
- Testing
- Hua Yu Wan Capsule, Aspirin
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Xuanwu Hospital, Beijing
Cochlear Implantation, Hearing Loss
Telerehabilitation & Telecoaching of Parents of Cochlear Implanted Children at Sohag University Hospital
Design online program for language sessions for cochlear implanted children in arabic and monitor its validity and reliability to improve language outcome
- Trial name
- NCT05122364
- Testing
- Telerehabilitation and telecoaching, Face to Face Language sessions
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Sohag University
Idiopathic Pulmonary Fibrosis
Azithromycin in the Management of Patients With Acute Exacerbation of Idiopathic Pulmonary Fibrosis
This randomized controlled trial evaluates the therapeutic role of azithromycin in acute exacerbations of idiopathic pulmonary fibrosis (AE-IPF).
- Trial name
- NCT05842681
- Testing
- Azithromycin, Methylprednisolone, Pirfenidone
- Where
- 2 sites in Egypt
- Volunteers
- 1,000 people
- Sponsor
- Assiut University
Substance Use Disorders
Facilitating Treatment Entry and Family Planning in Substance-using Neonatal Intensive Care Unit (NICU) Mothers
The purpose of this pilot study is to assess whether the hospital-based, adaptive behavioral intervention strategy promotes treatment entry and reduces risk of additional substance-exposed pregnancies (SEPs), as well as HIV and…
- Trial name
- NCT03165565
- Testing
- Motivational Interviewing (MI) and Acceptance and Commitment Therapy (ACT), Conventional Care
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- The University of Texas Health Science Center, Houston
Fluid Loss, Enhanced Recovery
Role of Goal Directed Fluid Therapy in Enhanced Recovery After Surgery in Gastro-intestinal Oncosurgeries
Enhanced recovery after surgery (ERAS) protocols are multimodal perioperative care pathways designed to achieve early recovery and reducing postoperative morbidity after surgical procedures by maintaining preoperative organ…
- Trial name
- GDFT ERAS (NCT06026475)
- Testing
- Goal directed Fluid Therapy, Conventional Fluid Therapy
- Where
- India
- Volunteers
- 60 people
- Sponsor
- Rajiv Gandhi Cancer Institute & Research Center, India
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