Clinical trials: Conventional therapy, completed
Ganglioneuroblastoma, Stage 1 Neuroblastoma
Busulfan, Melphalan, and Stem Cell Transplant After Chemotherapy in Treating Patients With Newly Diagnosed High-Risk Neuroblastoma
This pilot clinical trial studies busulfan, melphalan, and stem cell transplant after chemotherapy in treating patients with newly diagnosed neuroblastoma that is likely to come back or spread.
- Conditions
- Ganglioneuroblastoma, Stage 1 Neuroblastoma, Stage 2 Neuroblastoma, Stage 2A Neuroblastoma
- Trial name
- NCT01798004
- Testing
- Autologous Hematopoietic Stem Cell Transplantation, Busulfan, Cisplatin
- Where
- 123 sites in United States, Australia and 2 more
- Volunteers
- 150 people
- Sponsor
- Children's Oncology Group
Caries
Effectiveness of an ICCMS™ Caries Management Program.
The aim of this study is to compare in schoolchildren the effectiveness of an updated caries management program based on the current caries paradigm with the ICCMS™ system (International Caries Classification and Management…
- Trial name
- NCT04676230
- Testing
- Experimental group, Control group
- Where
- Colombia
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Universidad El Bosque, Bogotá
Non-metastatic, Hormone naïve Prostate Cancer
EXTEND Exercise Trial
This study will examine the effect of supervised exercise training on cardiopulmonary function in men receiving the combination of enzalutamide (ENZ) and androgen deprivation therapy (ADT) for treatment of non-metastatic…
- Trial name
- NCT02256111
- Testing
- Enzalutamide, Androgen deprivation therapy, Supervised exercise training
- Where
- 2 sites in United States
- Volunteers
- 26 people
- Sponsor
- Duke University
Obesity Difficult Airway Airway Management
Comparison of Video and Direct Laryngoscopy in Obese Patients During Surgery
This study aims to evaluate how intubation performed with two different brands of videolaryngoscope and the Macintosh laryngoscope during surgeries in obese patients requiring general anesthesia affects the VIDIAC score…
- Trial name
- NCT06973434
- Testing
- intubation
- Where
- Turkey (Türkiye)
- Volunteers
- 135 people
- Sponsor
- Harran University
HIV-associated Co-morbidities
Vitamin D Supplements for HIV-positive Patients on cART
The ability of vitamin D to modulate the immune system and strengthen bones may mitigate the adverse medication consequences of HIV/AIDS, but little is known about either the health benefits of vitamin D supplements, or about the…
- Trial name
- NCT01295034
- Testing
- conventional vitamin D treatment, tiered/titrated vitamin D dosing
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- Andrea Branch
Breast Cancer
Epirubicin in Treating Women Who Are Undergoing Surgery for Stage I, Stage II, or Stage III Breast Cancer
RATIONALE: Drugs used in chemotherapy, such as epirubicin, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing.
- Trial name
- NCT00253500
- Testing
- pegfilgrastim, epirubicin hydrochloride, conventional surgery
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Case Comprehensive Cancer Center
Carpal Tunnel Syndrome
Comparison of Two Techniques for the Treatment of Carpal Tunnel Syndrome
The main objective of this study is to compare the complete section of the transverse carpal ligament with another median nerve release technique and to determine if the incidence of post-surgical pillar pain is lower for either…
- Trial name
- STCCOT (NCT05468814)
- Testing
- Z-plasty, Conventional
- Where
- Spain
- Volunteers
- 120 people
- Sponsor
- Hospital Universitario Reina Sofia de Cordoba
Ototoxicity, Unspecified Childhood Solid Tumor, Protocol Specific
Assessing Ear Damage in Young Cancer Patients Treated With Cisplatin
RATIONALE: New ways to find out about hearing loss after treatment with chemotherapy may improve the ability to plan cancer treatment and may help patients live more comfortably.
- Trial name
- NCT00458887
- Testing
- management of therapy complications
- Where
- 81 sites in United States, Australia and 1 more
- Volunteers
- 301 people
- Sponsor
- Children's Oncology Group
Myofascial Trigger Point Pain, Knee Osteoarthritis
Effect of High Intensity Laser in Treatment of Myofascial Trigger Points in Symptomatic Knee Osteoarthritis
This study was conducted to investigate the effect of High intensity laser therapy( HILT) on pressure pain threshold, serum cortisol level, passive knee range of motion, and changes of functional disability in patients with…
- Trial name
- NCT05148416
- Testing
- High intensity laser treatment, knee osteoarthritis conventional exercises program
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Chronic Periodontitis
Evaluation Efficacy of Melatonin Gel as Adjunctive Therapy in Chronic Periodontitis
This study was conducted to assess the benefit of locally delivered melatonin gel as adjunctive to scaling and root planning (SRP) in the treatment of chronic periodontitis.
- Trial name
- NCT05759416
- Testing
- Melatonin2%gel
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
COVID19, Oxygen Therapy
Impact of Prone Position in Patients Under Spontaneous Breathing on Intubation or Non-invasive Ventilation or Death Incidence During COVID-19 Acute Respiratory Distress
The SARS-Cov2 viral pandemic is responsible for a new infectious disease called COVID-19 (CoronaVIrus Disease), is a major health problem.
- Conditions
- COVID19, Oxygen Therapy, Prone Position, Spontaneous Ventilation
- Trial name
- PROVID-19 (NCT04363463)
- Testing
- prone position
- Where
- 19 sites in France, Monaco
- Volunteers
- 268 people
- Sponsor
- Centre Hospitalier Régional d'Orléans
Ischemic Stroke
Registry Study of Stenting for Symptomatic Intracranial Artery Stenosis in China
The SAMMPRIS suggested that aggressive treatment was superior to intravascular stenting in patients with severe symptomatic intracranial atherosclerotic stenosis (ICAS) due to high complication rate in patients in stenting group.
- Trial name
- NCT01968122
- Testing
- intravascular stent therapy
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Zhongrong Miao
Neuroblastoma
Tandem High-dose Chemotherapy and Autologous Stem Cell Rescue in Patients With High-risk Neuroblastoma
The purpose of this study is to evaluate the efficacy and toxicity of tandem HDCT/ASCR in children with high-risk neuroblastoma. In the present study, a single arm trial of tandem HDCT/ASCR will be carried out.
- Trial name
- NCT00793845
- Testing
- Cyclophosphamide, Etoposide, Carboplatin
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Samsung Medical Center
COVID-19
Effectiveness of Remedesvir in COVID-19 Patients Presenting at Mayo Hospital Lahore
Currently, several drugs including Remdesivir, hydroxychloroquine, chloroquine, ritonavir+lopinavir, Tocilizumab, Arbidol and interferon are under randomised controlled trials (RCTs) for efficacy and/or safety evaluations in…
- Trial name
- NCT04871633
- Testing
- Remdesivir, Conventional
- Where
- Pakistan
- Volunteers
- 66 people
- Sponsor
- King Edward Medical University
Ovarian Cancer, Sarcoma
Combination Chemotherapy in Treating Patients With Sarcoma
RATIONALE: Drugs used in chemotherapy work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing.
- Trial name
- NCT00662233
- Testing
- cyclophosphamide, doxorubicin hydrochloride, etoposide
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Mayo Clinic
Bipolar Depression
12-Week Study Evaluating the Efficacy, Safety, and Tolerability of Adjunctive Infliximab for Bipolar I/II Depression
Studies show the presence of immuno-inflammatory disturbances in individuals with Bipolar Disorders (BD). Increased levels of circulating proteins known as cytokines that promote inflammation have been consistently reported in…
- Trial name
- NCT02363738
- Testing
- Infliximab, Saline
- Where
- 2 sites in United States, Canada
- Volunteers
- 60 people
- Sponsor
- University Health Network, Toronto
Parkinson Disease, Virtual Reality
Upper Extremity Rehabilitation With Virtual Reality in Parkinson's Disease Patients
Upper extremities are the first part of the body to be affected by Parkinson's disease. Although studies have shown that virtual reality-assisted rehabilitation methods are effective on gait and balance, studies on their use for…
- Conditions
- Parkinson Disease, Virtual Reality, Neurological Rehabilitation, Upper Extremity Dysfunction
- Trial name
- NCT06147726
- Testing
- Upper extremity position matching exercises in virtual reality, Conventional physiotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Ramazan KURUL
Arthritis, Arthritis, Rheumatoid
An MRI-guided Treatment Strategy to Prevent Disease Progression in Patients With Rheumatoid Arthritis
The purpose of this study is to examine whether an magnetic resonance imaging (MRI) -guided treatment strategy based on a predefined treatment algorithm can prevent progression of erosive joint damage, increase remission rate and…
- Conditions
- Arthritis, Arthritis, Rheumatoid, Joint Diseases, Musculoskeletal Diseases
- Trial name
- IMAGINE-RA (NCT01656278)
- Testing
- Magnetic resonance imaging (MRI), Conventional biochemical and clinical examinations
- Where
- 9 sites in Denmark
- Volunteers
- 200 people
- Sponsor
- Professor of Rheumatology, MD, DMSci, Kim Horslev-Petersen
Hodgkin Lymphoma, Refractory Hodgkin Lymphoma
Pentamidine + Salvage Chemo for Relapsed/Refractory Classical Hodgkin Lymphoma
Primary Objective: To evaluate dose limiting toxicity and to determine the recommended phase 2 dose (RP2D) of pentamidine in combination with salvage chemotherapy with ifosfamide, carboplatin and etoposide (ICE) on a 3-weeks…
- Trial name
- NCT03730363
- Testing
- Pentamidine
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Reinhold Munker
Amblyopia
Efficacy of Over-glasses Patch Treatment for Amblyopia in Children : OPTA Study
This is a study to investigate efficacy of over-glasses patch treatment for amblyopic children using visual function improvement and Amblyopia Treatment Index (ATI) changes.
- Trial name
- OPTA (NCT03080285)
- Testing
- over-glasses patch, Conventional patch
- Volunteers
- 107 people
- Sponsor
- Pusan National University Hospital
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