Clinical trials: Doxycycline, completed
Scrub Typhus
Clinical Effectiveness of Tigecycline for Scrub Typhus.
This multicenter, randomized, open-label clinical trial evaluated the efficacy and tolerability of intravenous tigecycline compared with oral doxycycline in adults hospitalized with scrub typhus.
- Trial name
- NCT07513103
- Testing
- doxycycline, Tigecycline (Tygacil)
- Where
- 3 sites in South Korea
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Jin Soo Lee
CoVid 19 Positive
The Fleming [FMTVDM] Directed CoVid-19 Treatment Protocol
Diagnostic determination of disease and treatment responses has been limited to qualitative imaging, measurement of serum markers of disease, and sampling of tissue.
- Trial name
- FMTVDM (NCT04349410)
- Testing
- Hydroxychloroquine, Azithromycin, Hydroxychloroquine, Doxycycline, Hydroxychloroquine, Clindamycin
- Where
- United States
- Volunteers
- 1,800 people
- Sponsor
- The Camelot Foundation
Familial Fatal Insomnia
Familiar Fatal Insomnia: Preventive Treatment With Doxycycline in Subject With Disease Risk
The neurodegenerative disorders is a class o pathologies including very common diseases as Alzheimer or Parkinson or very rare as fatal familial insomnia (FFI), the progression of the disease with no therapeutic remedy is the…
- Trial name
- FFI (NCT04846335)
- Testing
- Doxycycline Hcl
- Volunteers
- 29 people
- Sponsor
- Mario Negri Institute for Pharmacological Research
Metastatic Colorectal Cancer
Efficacy and Safety of the Prophylactic Use of Doxycycline +/- Vitamin K Cream
The aim of this Phase 2, two-arm, randomized, double blind placebo controlled study is to evaluate the efficacy of combination therapy of doxycycline and Vitamin K1 compared to doxycycline plus placebo for the prevention of…
- Trial name
- NCT01345526
- Testing
- Reconval K1 Cream, Reconval Cream
- Where
- 2 sites in Germany, Slovenia
- Volunteers
- 124 people
- Sponsor
- Universitätsmedizin Mannheim
To Determine Bioequivalence Under Fasting Conditions
Bioequivalence Study of Doxycycline Monohydrate Tablets Under Fasting Conditions
The purpose of this study is to compare the single-dose bioequivalence of Par and Oclassen doxycycline monohydrate, 100 mg.
- Trial name
- NCT01380483
- Testing
- doxycycline monohydrate
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Par Pharmaceutical, Inc.
Helicobacter Pylori Infection
Comparing Efficacy of 14-day Therapy Doxycycline With Bismuth Subsalicylate Versus Levofloxacin With Tinadizole on Treatment Helicobacter Pylori
Comparison Efficacy of 10-days Therapy with Doxycycline with Bismuth Subsalicylate Versus Levofloxacine with Tinadizole on Eradication of Helicobacter Pylori in Syrian population.
- Trial name
- NCT04348786
- Testing
- Doxycycline, Levofloxacin 500mg
- Where
- Syria
- Volunteers
- 78 people
- Sponsor
- Damascus Hospital
Duodenal Ulcer Due to Helicobacter Pylori
The Efficacy and Safety of Ilaprazole/Doxycycline-based Bismuth-containing Quadruple Therapy on Hp Infected Duodenal Ulcers
Helicobacter pylori (Hp) infection is one of the important causes of gastrointestinal diseases, including gastritis, peptic ulcer, and malignancies, nd the eradication of Hp can effectively cure or prevent these diseases.
- Trial name
- NCT03342456
- Testing
- Doxycycline Hyclate Enteric-Coated Capsules, Amoxicillin Capsules, Ilaprazole Enteric-Coated Tablets
- Where
- 7 sites in China
- Volunteers
- 184 people
- Sponsor
- The Third Xiangya Hospital of Central South University
Rash Due to Epidermal Growth Factor Receptor Inhibitors
Safety, Tolerability and Efficacy Study of Doxycycline Foam for the Prevention of EGFRI Skin Toxicity in Cancer Patients
The purpose of this study is to evaluate the safety, tolerability and efficacy of FDX104 Antibiotic Foam in the prevention of EGFRI skin toxicity in cancer patients receiving Cetuximab or Panitumumab.
- Trial name
- NCT02239731
- Testing
- FDX104 (4% Doxycycline)
- Where
- 7 sites in Israel
- Volunteers
- 24 people
- Sponsor
- Vyne Therapeutics Inc.
Erythema Migrans, Erythema Chronicum Migrans
Comparing 3 Antibiotic Regimes for Erythema Migrans in General Practice
Tick borne diseases are increasing in Norway. Lyme borreliosis is the most common infection. Erythema migrans is mainly diagnosed and treated in general practice.
- Conditions
- Erythema Migrans, Erythema Chronicum Migrans, Borreliosis, Lyme Disease
- Trial name
- NorTick_EM (NCT01368341)
- Testing
- Doxycycline, Phenoxymethylpenicillin, Amoxicillin
- Where
- Norway
- Volunteers
- 225 people
- Sponsor
- Morten Lindbaek
Rosacea
RosaC-RF : Bipolar Radiofrequency vs Doxycycline in Rosacea
Rosacea is a chronic facial disfiguring dermatosis characterized by different stages like flushing, erythema, telangiectasia and papulo-pustular lesions.
- Trial name
- Rosac-RF (NCT02204254)
- Testing
- Radiofrequence, Doxycycline
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Mansonella Perstans Infection, Buruli Ulcer
Concomitant Infections of Mansonella Perstans in Tuberculosis and Buruli Ulcer Disease Patients From Ghana
This study will determine the influence of doxycycline treatment against Wolbachia/M. perstans on immunity against concomitant mycobacterial infections in healthy M. perstans infected individuals.
- Conditions
- Mansonella Perstans Infection, Buruli Ulcer, Tuberculosis, Co-infection
- Trial name
- Map2Co (NCT02281643)
- Testing
- Doxycycline
- Where
- Ghana
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Kwame Nkrumah University of Science and Technology
Relapsing Fever, Tick-borne, Jarisch Herxheimer Reaction
Post Exposure Treatment With Doxycycline for the Prevention of Relapsing Fever
Abstract Background Tick-Borne Relapsing Fever (TBRF) is an acute febrile illness. In Israel, TBRF is caused by Borrelia persica and is transmitted by Ornithodoros tholozani ticks.
- Trial name
- NCT00237016
- Testing
- doxycycline treatment
- Where
- Israel
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Medical Corps, Israel Defense Force
Acne Vulgaris
Randomized Double-blind Study on the Benefit of Spironolactone for Treating Acne of Adult Woman.
Acne vulgaris of adult woman has increased over the past 10 years; it affects currently 20% to 30% of adult women. The physiopathology of adult woman acne is distinguished from the teenager one by essentially 2 factors: hormonal…
- Trial name
- FASCE (NCT03334682)
- Testing
- spironolactone, Doxycycline
- Where
- 9 sites in France
- Volunteers
- 158 people
- Sponsor
- Nantes University Hospital
Erythema Chronicum Migrans
Duration of Antibiotic Treatment of Erythema Migrans
The purpose of this study is to compare the efficacy of 15-day versus 10-day doxycycline treatment in patients with erythema migrans.
- Trial name
- NCT00910715
- Testing
- doxycycline
- Where
- Slovenia
- Volunteers
- 306 people, healthy volunteers welcome
- Sponsor
- University Medical Centre Ljubljana
Phototoxicity
Phototoxicity of Frequently Prescribed Medicines
This pilot trial aims to study 10 selected commonly prescribed medicines with different grade of phototoxic potential. As there is no currently established way to assess phototoxic potential in a systematic and quantitative way…
- Trial name
- Phototox (NCT06710600)
- Testing
- Single oral dose of selected medicines, respectively, UVA and UVB radiation
- Where
- Austria
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Crohn's Disease
Antibiotics and Hydroxychloroquine in Crohn's
There is growing evidence that Crohn's disease may be caused by replication of bacteria, perhaps particularly E. coli, within macrophages (a specialized sort of white blood cell).
- Trial name
- APRiCCOT (NCT01783106)
- Testing
- Ciprofloxacin, Doxycycline, Hydroxychloroquine
- Where
- United Kingdom
- Volunteers
- 59 people
- Sponsor
- Royal Liverpool University Hospital
Erythema Chronicum Migrans
Duration of Doxycycline Treatment in EM Patients
The purpose of this study is to compare the efficacy of 7-day versus 14-day doxycycline treatment in patients with erythema migrans.
- Trial name
- NCT03153267
- Testing
- Doxycycline 100 MG Oral Tablet bid, 7 days, Doxycycline 100 MG Oral Tablet bid, 14 days, Controls without a history of lyme disease.
- Where
- Slovenia
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University Medical Centre Ljubljana
Healthy
Bioequivalence Study of Doxycycline Monohydrate 100mg Tablets Under Fasting Conditions
The purpose of this study was to determine the bioequivalence of Doxycycline monohydrate formulations after administration of single doses to normal healthy subjects under fasted conditions.
- Trial name
- NCT00775177
- Testing
- Doxycycline monohydrate 100mg tablets
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Ranbaxy Laboratories Limited
Nasal Polyps, Chronic Rhinosinusitis With Nasal Polyps
Role of Doxycycline in Chronic Rhinosinusitis With Nasal Polyps
To evaluate the efficacy of Doxycycline as an adjunct to systemic steroids in the treatment of chronic rhinosinusitis with nasal polyps
- Trial name
- NCT05157412
- Testing
- Doxycycline 100 mg Oral Tablet, Prednisolone 20 mg
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Diabetes Mellitus With Periodontal Disease
The Effect of Topical Doxycycline Gel on HbA1c in Patients With Type 2 Diabetes Mellitus(DM) ®
Aim: The purpose of this study is to investigate the effect of nonsurgical periodontal therapy plus subgingivally doxycycline gel 3% on glycemic control in type 2 diabetes mellitus (type 2 DM) patients who have periodontitis.
- Trial name
- NCT02735837
- Testing
- Doxycycline Group
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Amirhossein Farahmand