Clinical trials: Escitalopram
Insomnia, Central Nervous System
A Clinical Study to Evaluate the Drug Interaction Between YZJ-1139 Tablets and Escitalopram Oxalate Tablets
Primary Objective： 1) To evaluate the pharmacodynamic interaction between YZJ-1139 tablets and Escitalopram oxalate tablets in healthy subjects; 2) To evaluate the pharmacokinetic interaction between YZJ-1139 tablets and…
- Trial name
- NCT06680531
- Testing
- YZJ-1139 tablets, Escitalopram oxalate tablets, YZJ-1139 simulated tablets
- Where
- China
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Shanghai Haiyan Pharmaceutical Technology Co., Ltd.
Obesity, Morbid
Bariatric Surgery and Pharmacokinetics of Escitalopram
Changes to gastric pH, gastric emptying time, gastrointestinal transit-time or the pre-systemic metabolizing effect of enzymes secreted in the mucosa may all alter the pharmacokinetics of medicines.
- Trial name
- NCT03460379
- Testing
- Escitalopram
- Where
- Norway
- Volunteers
- 12 people
- Sponsor
- Norwegian University of Science and Technology
Major Depression Disorder
Evaluation of the Safety of Adjunct Brexpiprazole in Elderly Patients With Major Depressive Disorder and an Inadequate Response to Antidepressant Treatment
The purpose of this study is to evaluate the safety and tolerability of brexpiprazole as adjunctive treatment in an elderly population with major depressive disorder and an inadequate response to antidepressant treatment
- Trial name
- NCT02400346
- Testing
- Adjunct brexpiprazole, ADT
- Where
- 34 sites in United States, Estonia and 3 more
- Volunteers
- 132 people
- Sponsor
- H. Lundbeck A/S
Major Depression
Functional Neuroimaging in Depression
Oral administration of escitalopram during 8 weeks; PET scan with 18F-FDG at inclusion and after 8 weeks
- Trial name
- NCT00343070
- Testing
- Oral administration of escitalopram during 8 weeks
- Where
- 2 sites in Belgium
- Volunteers
- 40 people
- Sponsor
- University Hospital, Ghent
Anxiety
Neurofunctional Predictors of Escitalopram Treatment Response in Adolescents With Anxiety
Neurofunctional Predictors of Escitalopram Treatment Response in Adolescents with Anxiety. To determine the effects of escitalopram on functional activation patterns during a Continuous Performance Task with Emotional and Neutral…
- Trial name
- FiESTAA (NCT02818751)
- Testing
- Escitalopram
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- University of Cincinnati
Functional Chest Pain
Effect of Citalopram on Chest Pain in Patients With Functional Chest Pain
Non-cardiac chest pain (NCCP) in the absence of musculoskeletal abnormalities, major esophageal motor disorders, gastroesophageal reflux or eosinophilic esophagitis is called functional chest pain (FCP).
- Trial name
- Ci-FCP (NCT05735756)
- Testing
- Citalopram 20mg
- Where
- Netherlands
- Volunteers
- 1 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Dyspepsia and Other Specified Disorders of Function of Stomach
Functional Dyspepsia Treatment Trial
Functional dyspepsia is a common gastrointestinal disorder. Symptoms can include stomach pain or discomfort, bloating, fullness after eating meals, and nausea.
- Trial name
- FDTT (NCT00248651)
- Testing
- Amitriptyline, Escitalopram
- Where
- 8 sites in United States, Canada
- Volunteers
- 292 people
- Sponsor
- Mayo Clinic
Major Depressive Disorder
A Pilot Study on Effect of add-on Sulforaphane to SSRIs and Application of Niacin Skin Flush Response Test in Major Depressive Disorder
A 12-week, randomized controlled trial (RCT) will be conducted to explore the effect of add-on sulforaphane (SFN) to selective serotonin reuptake inhibitors (SSRIs) for major depressive disorder (MDD).
- Trial name
- NCT05148169
- Testing
- SSRIs, SSRI plus Sulforaphane
- Where
- China
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Shanghai Mental Health Center
Major Depressive Disorder
EEG Biomarkers for Predicting Response to Antidepressant Therapy
The purpose of this study is to evaluate the potential early EEG predictors of an individual's response to treatment with antidepressant medications.
- Trial name
- NCT00289523
- Where
- 10 sites in United States
- Volunteers
- 375 people
- Sponsor
- Medtronic - MITG
Major Depressive Disorder
The Role of PKC Activation in the Immune-inflammatory Mechanism of Major Depressive Depression
Major Depressive disorder (MDD) is a heterogeneous mental illness. Treated with antidepressants that act on the neurotransmitter and/or their receptors just remitted only one third of patients with MDD, Thus, to improve the…
- Trial name
- NCT04156425
- Testing
- Escitalopram+golimumab, Escitalopram+Calcium Tablet, Escitalopram
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Shanghai Mental Health Center
Postpartum Depression
Escitalopram in the Treatment of Postpartum Depression
This will be an 8-week, open-label trial evaluating the efficacy of escitalopram as monotherapy in the treatment of patients with postpartum depression (PPD).
- Trial name
- NCT01527474
- Testing
- escitalopram
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- BC Women's Hospital & Health Centre
Pain, Polyneuropathies
Escitalopram as a Treatment for Pain in Polyneuropathy
Many people with polyneuropathy suffer from pain which is difficult to treat. Escitalopram is a relatively new drug used in the treatment of depression.
- Trial name
- NCT00162968
- Testing
- escitalopram
- Where
- 2 sites in Denmark
- Volunteers
- 50 people
- Sponsor
- Odense University Hospital
Coronary Artery Disease, Depression
The Recovery of Cardiovascular Patients With Depression
Cardiovascular disease increases the risk of depression and vice versa. Many cardiovascular patients are subjected to percutaneous coronary intervention (PCI).
- Conditions
- Coronary Artery Disease, Depression, Cardiovascular Diseases
- Trial name
- NCT03841474
- Testing
- Psychiatric treatment with sertraline, Psychiatric treatment with escitalopram
- Where
- Croatia
- Volunteers
- 150 people
- Sponsor
- Klinički Bolnički Centar Zagreb
Major Depression
Depression: The Search for Treatment-Relevant Phenotypes-Pilot Study
We are doing this pilot study to learn more about four aspects of treating depression: 1. The features of a depressed person's mood and anxiety and how these features affect a person's capacity to get better and stay better. 2.
- Trial name
- NCT00222820
- Testing
- escitalopram, Interpersonal Psychotherapy
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- University of Pittsburgh
Major Depressive Disorder (MDD) With Insomnia
Efficacy of Chronotherapeutic Combination for Major Depressive Episode With Insomnia
Major Depressive Disorder (MDD) affects 5% of the global population and is the second leading cause of disability worldwide. Despite the widespread use of antidepressants, 50-60% of patients do not respond adequately after 8…
- Trial name
- CombiChronoS (NCT07120880)
- Testing
- AD + SHR + active LT and extended-release melatonin 2mg
- Where
- France
- Volunteers
- 184 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Major Depressive Disorder
Pioglitazone as an Adjunct for Moderate to Severe Depressive Disorder
The purpose of this study is to determine whether Pioglitazone as an adjunct to Citalopram is effective in treatment of moderate to severe depression
- Trial name
- NCT01109030
- Testing
- Pioglitazone+Citalopram+Chlordiazepoxide
- Where
- Iran
- Volunteers
- 50 people
- Sponsor
- Tehran University of Medical Sciences
Major Depressive Disorder
Study of Neural Responses Induced by Antidepressant Effects
The proposed work aims to examine the neural changes associated with fast-acting antidepressant treatments in order to develop imaging-based biomarkers of treatment response for depression.
- Trial name
- SONRISA (NCT02674529)
- Testing
- Escitalopram, Real-time Neurofeedback fMRI task pre- and post-RCT
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Marta Peciña, MD PhD
Major Depressive Disorder
Role of Pentoxifylline as an Adjuvant Therapy for Adult Patients With Major Depressive Disorder
This study aimed to evaluate the therapeutic benefits of pentoxifylline (PTX) in treatment of adult patients with MDD as it has anti-inflammatory and phosphodiastrase inhibition activities.
- Trial name
- NCT03554447
- Testing
- Escitalopram 20 mg tablet plus Pentoxifylline 400Mg Tablet
- Volunteers
- 80 people
- Sponsor
- Mahmoud Samy Abdallah
Dementia
Discontinuation of Antipsychotics and Antidepressants Among Patients With BPSD
The aim of this study is to discontinue antipsychotics and antidepressants, and to study its effect on Behavioural- and Psychological Symptoms in Dementia (BPSD).
- Trial name
- NCT00433121
- Testing
- Risperidone, Olanzapine, Haloperidole
- Where
- Norway
- Volunteers
- 24 people
- Sponsor
- Sykehuset Innlandet HF
Friedreich Ataxia
An Objective Double-blind Evaluation of Bupropion and Citalopram in an Individual With Friedreich Ataxia
The purpose of this study is to document the clinical effects of bupropion and citalopram in a single subject with Friedreich Ataxia.
- Trial name
- NCT01716221
- Testing
- bupropion & Citalopram
- Volunteers
- 1 people
- Sponsor
- University of Colorado, Denver