Clinical trials: Etoposide, completed
Adenocarcinoma of the Lung, Adenosquamous Cell Lung Cancer
Radiation Therapy, Chemotherapy, and Soy Isoflavones in Treating Patients With Stage IIIA-IIIB Non-Small Cell Lung Cancer
This phase I trial studies the side effects of soy isoflavones when given together with radiation therapy and chemotherapy in treating patients with stage IIIA-IIIB non-small cell lung cancer.
- Conditions
- Adenocarcinoma of the Lung, Adenosquamous Cell Lung Cancer, Bronchoalveolar Cell Lung Cancer, Large Cell Lung Cancer
- Trial name
- NCT01958372
- Testing
- soy isoflavones, cisplatin, etoposide
- Where
- 5 sites in United States
- Volunteers
- 11 people
- Sponsor
- Barbara Ann Karmanos Cancer Institute
Glioblastoma, Astrocytoma
Stem Cell Transplant for High Risk Central Nervous System (CNS) Tumors
The primary goal of this study is to determine if a stem cell transplant in patients with newly diagnosed high risk CNS tumors (glioblastoma multiforme [GBM], high grade astrocytoma, pineoblastoma, rhabdoid tumor, supratentorial…
- Conditions
- Glioblastoma, Astrocytoma, Pineoblastoma, Rhabdoid Tumor
- Trial name
- NCT00179803
- Testing
- Stem Cell Transplant
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Diffuse Large B-cell Lymphoma
Clinical Trial to Determinate Dose, Security and Efficacy or Lenalidomide and Rituximab (LR)-ESHAP in Patients With Diffuse Large B-cell Lymphoma
The purpose of the Phase I of the study is to evaluate the safety and the maximum-tolerated dose (MTD) of the combination R-ESHAP with lenalidomide as salvage therapy for patients with relapsed or refractory diffuse large B-cell…
- Trial name
- NCT02340936
- Testing
- LR-ESHAP (lenalidomide 5 mg), LR-ESHAP (lenalidomide 10 mg), LR-ESHAP (lenalidomide 15 mg)
- Where
- 9 sites in Spain
- Volunteers
- 53 people
- Sponsor
- Grupo Español de Linfomas y Transplante Autólogo de Médula Ósea
Advanced Lung Cancer
JS004 Combined With Toripalimab and With Standard Chemotherapy Treat Patients With Advanced Lung Cancer
This is an open-label phase Ib/II clinical study to evaluate the safety, tolerability, pharmacokinetics and initial efficacy of JS004 injection combined with toripalimab and with or without standard chemotherapy in patients with…
- Trial name
- NCT05664971
- Testing
- Recombinant humanized anti-BTLA monoclonal antibody (JS004) injection, Toripalimab, Docetaxel
- Where
- China
- Volunteers
- 119 people
- Sponsor
- Shanghai Junshi Bioscience Co., Ltd.
Childhood Germ Cell Tumor, Drug/Agent Toxicity by Tissue/Organ
Combination Chemotherapy Plus Amifostine in Treating Children With Malignant Germ Cell Tumors
RATIONALE: Chemotherapy drugs use different ways to stop tumor cells from dividing so they stop growing or die. Chemoprotective drugs such as amifostine may protect normal cells from the side effects of chemotherapy.
- Conditions
- Childhood Germ Cell Tumor, Drug/Agent Toxicity by Tissue/Organ, Extragonadal Germ Cell Tumor, Ovarian Cancer
- Trial name
- NCT00003811
- Testing
- bleomycin sulfate, amifostine trihydrate, cisplatin
- Where
- 110 sites in United States, Australia and 4 more
- Volunteers
- 27 people
- Sponsor
- Children's Oncology Group
Small Cell Lung Cancer
A Study Comparing Etoposide/Cisplatin With Irinotecan/Cisplatin to Treat Extensive Disease Small Lung Cancer
This study is a randomized, multi-center clinical trial. Patients are stratified according to performance status (ECOG 0, 1 vs 2) and institution. Patients are randomized to 1 of 2 treatment arms.
- Trial name
- NCT00349492
- Testing
- IP
- Where
- 14 sites in South Korea
- Volunteers
- 372 people
- Sponsor
- Clinical Research Center for Solid Tumor, Korea
Sarcoma, Kaposi, HIV Infections
Phase II Evaluation of Low-Dose Oral Etoposide for the Treatment of Relapsed or Progressed AIDS-Related Kaposi's Sarcoma After Systemic Chemotherapy
To assess the toxicity, tumor response rate, and effect on quality of life of daily low-dose etoposide administered for 7 consecutive days every other week in patients with AIDS-related Kaposi's sarcoma that has relapsed or…
- Trial name
- NCT00000807
- Testing
- Etoposide
- Where
- 20 sites in United States
- Volunteers
- 41 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Extensive Stage Small Cell Lung Cancer, Unspecified Adult Solid Tumor, Protocol Specific
Cisplatin, Etoposide and PI3K Inhibitor BKM120 in Treating Patients With Advanced Solid Tumors or Small Cell Lung Cancer
This phase I trial studies the side effects and the best dose of PI3K inhibitor BKM120 when given together with cisplatin and etoposide in treating patients with advanced solid tumors or small cell lung cancer.
- Trial name
- NCT02194049
- Testing
- BKM120, cisplatin, etoposide
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- University of California, Davis
Lymphoma
Yttrium Y 90 Ibritumomab Tiuxetan, Etoposide, Cyclophosphamide, and an AHSCT in Non-Hodgkin's Lymphoma Patients
RATIONALE: Radiolabeled monoclonal antibodies, such as yttrium Y 90 ibritumomab tiuxetan, can find cancer cells and carry tumor-killing substances to them without harming normal cells.
- Trial name
- NCT00562978
- Testing
- filgrastim, cyclophosphamide, etoposide
- Volunteers
- 54 people
- Sponsor
- City of Hope Medical Center
Lung Cancer
Cisplatin, Etoposide, and Radiation Therapy in Treating Patients With Limited-Stage Small Cell Lung Cancer
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage tumor cells.
- Trial name
- NCT00066222
- Testing
- Cisplatin, Etoposide, Radiation therapy
- Where
- 104 sites in United States
- Volunteers
- 72 people
- Sponsor
- Radiation Therapy Oncology Group
Hodgkin Disease
Chemotherapy With or Without Radiation, Low and Intermediate Risk Hodgkins Lymphoma, TXCH-HD-12A
Subjects have a type of cancer called Hodgkin Disease (HD), a cancer of the lymph system. The lymph system is made up of tissue throughout the body that makes and stores infection-fighting cells.
- Trial name
- TXCH-HD-12A (NCT01858922)
- Testing
- ABVE-PC, DECA
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Baylor College of Medicine
Brain and Central Nervous System Tumors, Head and Neck Cancer
Chemotherapy Plus Peripheral Stem Cell Transplant in Treating Patients With Central Nervous System Cancer
RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining chemotherapy with peripheral stem cell transplant may allow the doctor to give higher doses of…
- Conditions
- Brain and Central Nervous System Tumors, Head and Neck Cancer, Lymphoma
- Trial name
- NCT00007982
- Testing
- filgrastim, carmustine, cisplatin
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Herbert Irving Comprehensive Cancer Center
Retinoblastoma
CEV With/Without Periocular Carboplatin Chemotherapy for Extraocular Retinoblastoma
This study will evaluate a uniform chemotherapy protocol for nonmetastatic extraocular retinoblastoma
- Trial name
- NCT02319486
- Testing
- carboplatin periocular injection, CEV chemotherapy
- Volunteers
- 26 people
- Sponsor
- Sun Yat-sen University
Lymphoma
Combination Chemotherapy in Treating Children With Lymphoma
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells.
- Trial name
- NCT00002590
- Testing
- filgrastim, cyclophosphamide, cytarabine
- Where
- 33 sites in United States, Australia and 1 more
- Volunteers
- 221 people
- Sponsor
- Children's Oncology Group
Lymphoma
Fludeoxyglucose F 18-PET/CT Imaging in Assessing Response to Chemotherapy in Patients With Newly Diagnosed Stage II, Stage III, or Stage IV Hodgkin Lymphoma
RATIONALE: Imaging procedures, such as fludeoxyglucose F 18 (FDG)-PET/CT scan, done before, during, and after chemotherapy may help doctors assess a patient's response to treatment and help plan the best treatment.
- Trial name
- NCT00678327
- Testing
- bleomycin sulfate, filgrastim, pegfilgrastim
- Where
- United Kingdom
- Volunteers
- 1,202 people
- Sponsor
- University College, London
Hodgkin Lymphoma, Lymphoma
Velcade Plus ICE for Patients With Relapsed Classical Hodgkin Lymphoma
Primary Objectives: 1. To determine the toxicity profile of multiple doses of bortezomib when given with ICE in patients with relapsed and refractory classical Hodgkin lymphoma (HL). 2.
- Trial name
- NCT00439361
- Testing
- Bortezomib, Carboplatin, Etoposide
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- M.D. Anderson Cancer Center
Extensive-stage Small Cell Lung Cancer
Phase II Study of Irinotecan and Cisplatin in Extensive-stage Small Cell Lung Cancer
Patients with untreated extensive-stage small cell lung cancer(SCLC) were randomly assigned to receive either irinotecan/cisplatin (IP) or etoposide/cisplatin(EP), The association of efficacy and toxicity of IP regimen was…
- Trial name
- NCT02323737
- Testing
- Irinotecan and cisplatin, Etoposide and cisplatin
- Where
- China
- Volunteers
- 62 people
- Sponsor
- Chinese Academy of Medical Sciences
Multiple Myeloma
Tandem Transplantation in Multiple Myeloma (MM) Patients With <12 Months of Prior Treatment
The two objectives of this study are: To increase the 2-year event-free survival from 55%, established with Total Therapy II (UARK 98-026), to 75% in myeloma patients with cytogenetic abnormalities, and from 80%, established with…
- Trial name
- NCT00670631
- Testing
- tandem autologous transplantation
- Volunteers
- 46 people
- Sponsor
- Guido Tricot
Childhood Burkitt Lymphoma, Childhood Diffuse Large Cell Lymphoma
Rituximab, Rasburicase, and Combination Chemotherapy in Treating Young Patients With Newly Diagnosed Advanced B-Cell Leukemia or Lymphoma
Phase II trial to study the effectiveness of combining rituximab and rasburicase with combination chemotherapy in treating young patients who have newly diagnosed advanced B-cell leukemia or lymphoma.
- Conditions
- Childhood Burkitt Lymphoma, Childhood Diffuse Large Cell Lymphoma, Childhood Immunoblastic Large Cell Lymphoma, Stage I Childhood Large Cell Lymphoma
- Trial name
- NCT00057811
- Testing
- doxorubicin hydrochloride, cyclophosphamide, methotrexate
- Where
- United States
- Volunteers
- 97 people
- Sponsor
- Children's Oncology Group
Small Cell Lung Cancer
Carboplatin, Etoposide, and Atezolizumab With or Without Trilaciclib (G1T28), a CDK4/6 Inhibitor, in Extensive-Stage SCLC
This was a study to investigate the potential clinical benefit of trilaciclib (G1T28) in preserving the bone marrow and the immune system, and enhancing antitumor efficacy when administered with carboplatin, etoposide, and…
- Trial name
- NCT03041311
- Testing
- Trilaciclib, Carboplatin, Etoposide
- Where
- 45 sites in United States, Bulgaria and 5 more
- Volunteers
- 107 people
- Sponsor
- G1 Therapeutics, Inc.