Clinical trials: Exercise Intervention
Cancer, Childhood Cancer
Decision Aid for Education and Support About Cancer Treatment
The goals of this clinical trial are to evaluate DECIDES, a web-based decision support application that provides education about cancer and cancer treatment and provides support to encourage adolescent and young adult (AYA)…
- Trial name
- DECIDES B+ (NCT06191679)
- Testing
- Decision Aid for Education and Support about Cancer Treatment (DECIDES Intervention)
- Where
- United States
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Diabetic Neuropathies
Effects of Foot Muscle Strengthening in Daily Activity in Diabetic Neuropathic Patients
The main objective of this trial is to investigate the effects of foot muscle strengthening in daily activity of patients with diabetic neuropathy.
- Trial name
- NCT02790931
- Testing
- Intervention Group
- Where
- Brazil
- Volunteers
- 78 people
- Sponsor
- University of Sao Paulo General Hospital
Scleroderma, Scleroderma, Systemic
Evaluation of the Scleroderma Patient-centered Intervention Network COVID-19 Home-isolation Activities Together Program
Contagious disease outbreaks, such as the coronavirus disease 2019 (COVID-19) outbreak, and associated restrictions to prevent spread can lead to negative psychological outcomes, including loneliness, depression, and anxiety…
- Conditions
- Scleroderma, Scleroderma, Systemic, Systemic Sclerosis
- Trial name
- SPIN-CHAT (NCT04335279)
- Testing
- SPIN-CHAT Program
- Where
- Canada
- Volunteers
- 172 people
- Sponsor
- Lady Davis Institute
Osteoarthritis, Knee, Hypertension
Staying Active With Arthritis: RCT of Physical Activity for Older Adults With Osteoarthritis and Hypertension
The purpose of the Staying Active with Arthritis (STAR) research study is to determine if a 6-month program will improve leg exercise, fitness walking, and clinical outcomes (function, blood pressure, leg strength, pain, fatigue…
- Trial name
- STAR (NCT01280903)
- Testing
- STAR Intervention, Attention-Control
- Where
- United States
- Volunteers
- 182 people
- Sponsor
- University of Pittsburgh
Type 2 Diabetes Mellitus
A Study to Examine the Pharmacokinetics, Tolerability, Safety and Efficacy of Exenatide Once Weekly Suspension
This study is designed to evaluate the pharmacokinetics, tolerability, and safety of exenatide once weekly suspension in both healthy subjects and in subjects with type 2 diabetes.
- Trial name
- NCT00894322
- Testing
- exenatide once weekly
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- AstraZeneca
Mild Cognitive Impairment
Applying a Person-Centered Approach to Enhance Cognitive Training in Senior Living Community Residents With Mild Cognitive Impairment
Computerized cognitive interventions (CCIs) have been increasingly widely implemented among older adults with mild cognitive impairment (MCI).
- Trial name
- CogT-PACT (NCT03292705)
- Testing
- PEP, CCI
- Where
- 2 sites in United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Multiple Sclerosis
Exploring the Use of Non-invasive Neuromodulation Combined With Exercise in People With Advanced Multiple Sclerosis (MS)
The investigators hypothesis is that electrical stimulation to the tongue that directly stimulates two cranial nerve nuclei (Trigeminal and Facial Nerve Nuclei), will excite neural impulses to the brainstem and cerebellum.
- Trial name
- NCT02252666
- Testing
- Neuromodulation Rehabilitation
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- University of Wisconsin, Madison
Opioid-use Disorder, Anxiety Disorders
Digital Intervention to Treat Anxiety and Depression Among Persons Receiving Treatment for Opioid Use Disorder
The majority of opioid users meet criteria for anxiety and depressive disorders, but most substance use disorder treatment programs do not offer treatment for co-occurring mental health problems.
- Conditions
- Opioid-use Disorder, Anxiety Disorders, Depressive Disorder
- Trial name
- NCT05047627
- Testing
- Smartphone-Based Digital Intervention
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- Trustees of Dartmouth College
GDM
A Co-created Self-care and Informal Support Intervention Study Among Women With GDM in Vietnam
Gestational Diabetes Mellitus (GDM) is significant public health problem in Vietnam, which is potentially treatable if managed properly by the pregnant women once diagnosed.
- Trial name
- VALID-II (NCT05744856)
- Testing
- Self-care with informal support
- Where
- 2 sites in Vietnam
- Volunteers
- 435 people, healthy volunteers welcome
- Sponsor
- Thai Binh University of Medicine and Pharmacy
Physical Activity, Acute Coronary Syndrome
Evaluating Increasing Physical Activity After Acute Coronary Syndrome
This study will use a randomized, controlled trial to test the effectiveness of a home-based physical activity program using wearable devices and financial incentives.
- Trial name
- NCT02531022
- Testing
- Financial incentive, Daily feedback
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Obesity
Study of Serum Markers for Cardiovascular Risk in Obese Youth and Impact of Lifestyle and Medication Intervention
In Protocol #2, we will select 30 obese pubertal and 30 obese prepubertal subjects with an abnormal cytokine profile (i.e. fibrinogen and/or hsCRP concentration greater than or equal to 2 Standard Deviations (SD) above the mean…
- Trial name
- NCT00139477
- Testing
- Metformin, Dietary modification with caloric restriction, Establishment of exercise protocol
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Nemours Children's Clinic
Respiratory Disease
Comparing 6-Minute Walk Tests for Ambulatory Oxygen Assessment
Patients with lung disease who report breathlessness on exertion are often referred for a 6MWT. Due to the nature of the 6MWT (hereon referred to as a Max-6MWT), patients are required to walk as far as they can in 6 minutes.
- Trial name
- NCT05630092
- Testing
- Maximal 6-minute Walk Test (Max_6MWT), Normal speed 6-minute Walk Test (Nor_6MWT)
- Where
- United Kingdom
- Volunteers
- 93 people
- Sponsor
- Hampshire Hospitals NHS Foundation Trust
Rheumatoid Arthritis
App-based Education and GOal-setting in Rheumatoid Arthritis
The purpose of this pragmatic, investigator-initiated, multicentre randomised controlled trial is to study the effectiveness and feasibility of a mobile app-based self-management intervention for patients with rheumatoid…
- Trial name
- AEGORA (NCT05888181)
- Testing
- Mobile app-based self-management intervention
- Where
- 2 sites in Belgium
- Volunteers
- 128 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Heart Disease (Coronary Artery Disease, Ischemic Heart Disease, Hypertensive Heart Disease), Uncontrolled Diabetes (HBA1c ≥ 10)
Piloting the IPROACTIF Program to Preserve Functioning and Prevent Cognitive Decline
Conduct a pilot randomized control to assess the preliminary efficacy of IPROACTIF, an occupational therapist-delivered primary care intervention for aging and chronic disease management.
- Trial name
- NCT04682977
- Testing
- IPROACTIF (Integrated PRimary Care and Occupational Therapy for Aging and Chronic Disease Treatment to preserve Independence and Functioning), Usual primary care services
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- University of Illinois Chicago
COPD Exacerbation
Increasing Adherence to Pulmonary Rehabilitation After COPD Related Hospitalizations (Pilot Study)
This pilot study will look at investigating barriers, facilitators, adherence and effectiveness of an interactive home-based pulmonary rehabilitation program and health coaching for patients who have recently been hospitalized…
- Trial name
- NCT03865329
- Testing
- Intervention- Home-based Pulmonary Rehabilitation
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Mayo Clinic
Gynecology
An Endometrial Cancer Chemoprevention Study of Metformin
The goal of this clinical research study is to learn about the effects of metformin and/or a program called "lifestyle intervention" on the endometrium (inner lining of the uterus) in post-menopausal women who are also obese…
- Trial name
- NCT01697566
- Testing
- Metformin, Endometrial Biopsy, Lifestyle Intervention
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Stress, Psychological
Yoga and Aerobic Exercise Effects on Cognition
The purpose of this acute randomized control study is to assess the feasibility of a low-to-moderate intensity Yoga intervention (i.e.
- Trial name
- NCT04077645
- Testing
- Sun salutations, Aerobic exercise, Seated rest
- Where
- United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign
Obesity, Anxiety Sensitivity
Computer-Delivered Intervention for Individuals With Obesity and Elevated Anxiety Sensitivity
The proposed study will design and evaluate a computerized-delivered single-session anxiety sensitivity reduction program (i.e., Anxiety Sensitivity Training; AST).
- Conditions
- Obesity, Anxiety Sensitivity, Eating, Physical Activity
- Trial name
- NCT03917901
- Testing
- Anxiety Sensitivity Training, Health Control
- Where
- United States
- Volunteers
- 131 people
- Sponsor
- University of Houston
Endometrial Cancer, Obesity
FitEx for Endometrial Cancer Survivors: Initial Efficacy
The goal of this clinical trial is to compare physical activity outcomes between endometrial cancer survivors randomized to 1 of 3 conditions: 1) usual care, 2) FitEx, 3) FitEx+yoga.
- Conditions
- Endometrial Cancer, Obesity, Sedentary Behavior, Quality of Life
- Trial name
- NCT05737745
- Testing
- Self-monitoring, Group-dynamics, Weekly virtual sessions- Standard
- Where
- United States
- Volunteers
- 111 people
- Sponsor
- Carilion Clinic
Cardiovascular Diseases, Cardiac Surgery
Technological Platforms and Telerehabilitation in Heart Surgery
In this randomised, double-blind, pilot study, the investigators aim to assess whether a telerehabilitation strategy could improve outcomes among patients with recent heart surgery.
- Trial name
- NCT02653326
- Testing
- Telerehabilitation Monitors, Physical Therapy, Nutritional Counseling
- Where
- 2 sites in Chile
- Volunteers
- 66 people
- Sponsor
- Universidad de Valparaiso
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