Clinical trials: Exercise Intervention
Hypertension, Cognitive Decline
The Heart & Mind Study
Older adults with subjective cognitive decline (SCD) may represent a portion of the population experiencing early sings of cognitive decline. Systolic hypertension is a major contributor to cognitive impairment.
- Conditions
- Hypertension, Cognitive Decline, Vascular Cognitive Impairment
- Trial name
- NCT03545958
- Testing
- High-intensity Interval Training (HIT), Moderate-intensity Continuous Training (MCT)
- Where
- Canada
- Volunteers
- 140 people
- Sponsor
- Western University, Canada
Metastatic Breast Cancer, Cancer-Related Fatigue
Multimodal Exercise and Education Program in Metastatic Breast CancerMostrar más líneas
This longitudinal pre-post study evaluates the effects of a 12-week community-based multimodal intervention combining supervised physical exercise and health education in women with metastatic breast cancer receiving active…
- Conditions
- Metastatic Breast Cancer, Cancer-Related Fatigue, Quality of Life
- Trial name
- MBC_MME (NCT07693985)
- Testing
- Multimodal Oncology-Based Intervention for Metastatic Breast Cancer
- Where
- Spain
- Volunteers
- 37 people
- Sponsor
- University of Valencia
Vascular Stiffness, Cardiorespiratory Fitness
Comparison of Home- vs. Gym-based Exercise Delivery Modes
Home-based exercise interventions were the only alternatives to attenuate physical deconditioning and ameliorate traditional and emergent cardiovascular risk factors progression during the COVID-19 outbreak.
- Trial name
- UPSIDE DOWNS (NCT05701943)
- Testing
- Home-Based, Gym-Based
- Where
- Portugal
- Volunteers
- 17 people
- Sponsor
- Egas Moniz - Cooperativa de Ensino Superior, CRL
Osteoporosis, Postmenopausal
Effect of Mechanical Loading With PTH on Cortical Bone
Clinical trial to investigate effect of voluntary upper extremity loading in combination with anabolic osteoporosis therapy.
- Trial name
- NCT03232476
- Testing
- Upper extremity voluntary loading
- Volunteers
- healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Chronic Pain, Breast Neoplasms
Breathing Exercise for Chronic Pain Management in Breast Cancer Survivors
The study will follow the MRC Framework to develop an evidence-based BE intervention protocol to help breast cancer survivors with better management of cancer-related chronic pain.
- Conditions
- Chronic Pain, Breast Neoplasms, Cancer Survivors
- Trial name
- NCT05257876
- Testing
- Breathing exercise
- Where
- China
- Volunteers
- 72 people
- Sponsor
- Charles Darwin University
GLP - 1, Obesity & Overweight
Combatting Muscle Loss in Obese Adult Patients on GLP-1 Medications Through Dietary Counseling and Exercise During Treatment Evaluates Whether a 12-week Exercise and Individualized Nutrition Program Can Reduce Muscle and Bone Loss and Improve Strength, Fitness, and Function in Obese Adults on GLP-1
Obesity remains a critical public health challenge and is associated with increased rates of morbidity, mortality, and chronic disease worldwide.
- Conditions
- GLP - 1, Obesity & Overweight, Muscle Loss, Exercise Intervention
- Trial name
- NCT07554417
- Testing
- Semaglutide, Dietary Counseling, Exercise
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- William Marsh Rice University
Medulloblastoma
A Clinical and Molecular Risk-Directed Therapy for Newly Diagnosed Medulloblastoma
Historically, medulloblastoma treatment has been determined by the amount of leftover disease present after surgery, also known as clinical risk (standard vs. high risk).
- Trial name
- NCT01878617
- Testing
- Craniospinal Irradiation with boost to the primary tumor site, Cyclophosphamide, Cisplatin
- Where
- 23 sites in United States, Australia and 2 more
- Volunteers
- 660 people
- Sponsor
- St. Jude Children's Research Hospital
HIV
The Safety and Immunogenicity of the DNA-GTU Vaccine Administered to HIV-infected Patients on ART vs Placebo
CUT*HIVTHER 001 is a randomised placebo-controlled Phase I/II study aimed at exploring the safety and immunogenicity of two different modes of delivery of a GTU® DNA plasmid vaccine (GTU®-multiHIV B clade) in HIV infected…
- Trial name
- CUTHIVTHER001 (NCT02457689)
- Testing
- GTU®-MultiHIV B Clade Vaccine, Sodium chloride BP
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Imperial College London
Acute Myocardial Infarction Type 1, Myocardial Injury
TROPOnin FRAGMentation in Myocardial Injury Study
Troponin T (TnT) is a part of the troponin protein complex that principally exists in cardiac and skeletal muscle cells and is widely used as diagnostic biomarker for myocardial injury and, thus, myocardial infarction (MI).
- Trial name
- Tropo-Fragm (NCT04465591)
- Testing
- troponin T fragmentation test
- Where
- 2 sites in Finland, Switzerland
- Volunteers
- 1,500 people
- Sponsor
- University of Turku
Parkinson Disease
Effects of Home-based High-speed Bodyweight Resistance Training in Individual With Parkinson's Disease
Exercises that involve increasing the speed of movements are beneficial for individuals with Parkinson's disease (PD) and have the potential to reduce bradykinesia and improve mobility.
- Trial name
- NCT06646523
- Testing
- High-speed bodyweight resistance training, Control group (Bodyweight intervention, usual speed)
- Where
- Brazil
- Volunteers
- 46 people
- Sponsor
- Federal University of Minas Gerais
Chronic Kidney Disease, Diabetes
Diabetes CKD Lifestyle Technology Study
The purpose of this study is to pilot test an mHealth technology-supported behavioral intervention designed to engage patients with diabetes and concurrent chronic kidney disease (CKD) in multiple behaviors which aim to reduce…
- Conditions
- Chronic Kidney Disease, Diabetes, Obesity
- Trial name
- NCT02266823
- Testing
- Social Cognitive Theory
- Where
- United States
- Volunteers
- 270 people
- Sponsor
- NYU Langone Health
Dynamic Knee Valgus, Frontal Plan Projection Angle
Effect of Corrective Exercises on Dynamic Knee Valgus
Dynamic knee valgus (DKV) is a movement pattern of the lower limb potentially consisting of a combination of adduction and internal rotation of the femur, knee abduction, tibial anterior translation, tibial external rotation and…
- Conditions
- Dynamic Knee Valgus, Frontal Plan Projection Angle, Motion Analysis, Corrective Exercise
- Trial name
- NCT06776562
- Testing
- Exercise, Control
- Where
- Turkey (Türkiye)
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Medipol University
Breast Cancer Related Lymphedema
Effect of BOSU Exercises Added to Complete Decongestive Treatment on Balance in Breast Cancer-associated Lymphedema.
The aim of the study is to investigate the effect of balance exercises performed with the BOSU ball added to complete decongestive treatment on static and dynamic balance in patients with breast cancer-related lymphedema.
- Trial name
- NCT06182046
- Testing
- Complete decongestive treatment program, Balance exercises
- Volunteers
- 40 people
- Sponsor
- Oya Topuz
Adherence, Treatment, Exercise
Exploring the Effectiveness to Web-based Exercise Among Community-dwelling Adults With High Body Fat
The study findings can derive an effective exercise type either web-based or supervise exercise as well as build a series of exercise video that can promote self-exercise at home for health promotion for community residents.
- Trial name
- NCT05957861
- Testing
- web-based aerobic exercise
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- National Tainan Junior College of Nursing
Double Leg Vertical Jump (DLVJ), Single Leg Squat (SLS)
ESSKA/ESMA ACL Injury Prevention Program in Czech Sport
This study aims to address the rising incidence of ACL injuries, particularly among adolescents, by developing and implementing a comprehensive prevention program based on the evidence-based "ACL Prevention for ALL" framework…
- Conditions
- Double Leg Vertical Jump (DLVJ), Single Leg Squat (SLS), Single Leg Drop Landing (SLDL), Drop Jump Test (DJ Test)
- Trial name
- NCT07019727
- Testing
- ESSKA/ESMA 'ACL Prevention for All' methodology
- Where
- Czechia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Masaryk University
Acquired Brain Injury
Exercise Therapy Program on Acquired Brain Injury
In this study, the physical and psychosocial effects of a exercise therapy and adapted physical activity program based on racket sports for ambulant people with acquired brain injury will be investigated.
- Trial name
- NCT05358470
- Testing
- Exercise therapy and adapted physical activity-based program
- Where
- Spain
- Volunteers
- 23 people
- Sponsor
- Universidade da Coruña
Fibromyalgia, Chronic Fatigue Syndrome (CFS)
Effect of Physical Exercise and Neuromodulation on Pain, Sleep and Fatigue in Patients With Fibromyalgia
Fibromyalgia (FMS) is a chronic, multifactorial syndrome characterized by widespread pain, fatigue, and cognitive disturbances. This interventional study evaluates the impact of structured physical training using…
- Trial name
- NCT07242573
- Testing
- Physical Training Program, NESA X-Signal, Conventional Physiotherapy
- Where
- Poland
- Volunteers
- 75 people
- Sponsor
- National Institute of Geriatrics, Rheumatology and Rehabilitation, Poland
Mitral Valve Insufficiency
Determinants of the Progression and Outcome of Mitral Regurgitation
Mitral regurgitation (MR) is one of the most frequent valve lesions, both in North America and in Europe, and its prevalence is increasing with the aging of the population.
- Trial name
- PROGRAM (NCT01835054)
- Testing
- Blood biomarkers, DNA collection, Echocardiography
- Where
- 4 sites in Belgium, Canada and 1 more
- Volunteers
- 440 people
- Sponsor
- Laval University
Esophageal Cancer
Prehabilitation in Esophageal Cancer Care
Prehabilitation utilizes the preoperative period to prevent or attenuate the treatment-related functional decline and its consequences.
- Trial name
- NCT04581005
- Testing
- Prehabilitation
- Where
- Canada
- Volunteers
- 54 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Parkinson Disease, Freezing of Gait
Remote Mental Practice for Freezing of Gait in Parkinson's Disease
This single-blind, randomized controlled trial investigates the effects of a remotely delivered intervention based on mental practice (MP) combined with physical practice (PP) on freezing of gait (FOG) severity in people with…
- Trial name
- NCT06957405
- Testing
- MPPG (Mental and Physical Practice Group), PPG (Physical Practice Group)
- Where
- Brazil
- Volunteers
- 50 people
- Sponsor
- University of Sao Paulo General Hospital
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.