Clinical trials: Experimental, completed
Constipation
Aromatherapy Massage Applied on Constipation
Aim: This study was conducted as a randomized controlled experimental study to examine the effect of abdominal massage with ginger and lavender oil on constipation in elderly individuals.
- Trial name
- Aromatherapy (NCT04513093)
- Testing
- Aromatherapy Massage
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Ayşe Aydınlı
Venous Thromboembolism, Venous Thrombosis
Educating Nurses About Venous Thromboembolism (VTE) Prevention
As part of mandatory on-going nursing education, the investigators have incorporated identical information into two distinct web-based learning formats - the traditional linear PowerPoint format (with voice-over) and a new…
- Trial name
- NCT02301793
- Testing
- Nurse education in contemporary format, Nurse education in traditional format
- Where
- United States
- Volunteers
- 933 people
- Sponsor
- Johns Hopkins University
Early Life Adversity, Chronic Stress
Health Experiences & Early Life Disadvantages
Growing up in a low-income household has been shown to increase risk for, and susceptibility to many illnesses.The purpose of the study is to test an affective intervention for reversing biological risk factors, as related to…
- Trial name
- HEELD (NCT02400593)
- Testing
- Meditation Workshop
- Where
- United States
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Skin and Subcutaneous Tissue Bacterial Infections, Gram-Positive Bacterial Infections
TNP-2092 to Treat Acute Bacterial Skin and Skin Structure Infection
The purpose of this study is to evaluate safety, tolerability, pharmacokinetic characteristics and efficacy of TNP-2092 in adults with ABSSSI suspected or confirmed to be caused by gram-positive pathogens.
- Trial name
- P2_ABSSSI (NCT03964493)
- Testing
- TNP-2092, Vancomycin
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- TenNor Therapeutics Limited
Self-Help Devices, Eye-Gaze Technology
Applying Eye-Gaze Assistive Technology for Children and Youth With Complex Needs
The purpose of this research is to investigate the impacts of applying eye-gaze assistive technology (AT) in children and youth with severe disabilities and complex needs in Taiwan, where eye-gaze AT has not been researched for…
- Conditions
- Self-Help Devices, Eye-Gaze Technology, Severe Physical Disabilities, Communication Disorders
- Trial name
- NCT04377893
- Testing
- Eye gaze AT intervention
- Where
- Sweden
- Volunteers
- 5 people
- Sponsor
- Yu-Hsin Hsieh
Solid Tumors
MSB0011359C (M7824) in Participants With Metastatic or Locally Advanced Solid Tumors
The main purpose of this study was to assess the safety and tolerability of MSB0011359C. Study consists of dose-escalation part and an expansion part in participants with metastatic or locally advanced solid tumors, for which no…
- Trial name
- NCT02699515
- Testing
- MSB0011359C
- Where
- 18 sites in Japan, South Korea and 1 more
- Volunteers
- 114 people
- Sponsor
- Merck KGaA, Darmstadt, Germany
Constriction, Pathologic
FLAIR™ Delivery System Study
The objective of this clinical study is to evaluate the performance of the Optimized FLAIR™ Delivery System.
- Trial name
- FLAIR DS (NCT00614315)
- Testing
- FLAIR™ Endovascular Stent Graft
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- C. R. Bard
Glaucoma, Ocular Hypertension
Multiple Dose-escalation Study of AMA0076 in Patients With Ocular Hypertension or Primary Open-angle Glaucoma
The objective of this dose-escalation study is to evaluate the safety, tolerability and efficacy of AMA0076 in reduction of intraocular pressure in subjects with ocular hypertension or primary open-angle glaucoma.
- Conditions
- Glaucoma, Ocular Hypertension, Eye Disease
- Trial name
- NCT01693315
- Testing
- AMA0076
- Where
- 6 sites in United States
- Volunteers
- 82 people
- Sponsor
- Amakem, NV
Asthma
Clinical Study to Explore the Efficacy of ACT-129968 in Patients With Partly Controlled Asthma
This study will assess the efficacy and safety of ACT-129968 in subjects with partly controlled asthma on reliever therapy only.
- Trial name
- CONTROL (NCT01225315)
- Testing
- Setipiprant
- Where
- 97 sites in United States, Australia and 11 more
- Volunteers
- 438 people
- Sponsor
- Idorsia Pharmaceuticals Ltd.
Respiratory Distress Syndrome, Adult
STUDY OF ELECTRICAL STIMULATION IN PULMONARY FUNCTION IN INTENSIVE CARE UNIT
Introduction: The Mechanical Ventilation (MV), a support method used in Intensive Care Units (ICU), reaches approximately 90% of critical patients whose withdrawal process represents 40% of the total time of their use.
- Trial name
- NCT03712215
- Testing
- Rehabilitation
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- Universidade Metodista de Piracicaba
COVID-19 Vaccination
HOPE Intervention for COVID-19
The Harnessing Online Peer Education COVID-19 (HOPE COVID-19) intervention will assess whether a peer-led online support community can improve behavioral health outcomes related to COVID-19.
- Trial name
- NCT04376515
- Testing
- HOPE intervention
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Chronic Hemodialysis (ESRD)
Safety and Cardiovascular Efficacy of Hydralazine and Isosorbide Dinitrate in Dialysis-Dependent ESRD
This study is a pilot study designed to compare the safety and cardiovascular effects of 26 weeks of combination hydralazine/isorsorbide dinitrate therapy with placebo therapy in patients receiving chronic hemodialysis.
- Trial name
- HIDE (NCT02228408)
- Testing
- Hydralazine/Isorsorbide Dinitrate
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Brigham and Women's Hospital
Mycoplasma Genitalium Infection
Prospective, Monocentric, Interventional Study on Spontaneous Vaginal Clearance of Mycoplasma Genitalium
It is a prospective, monocentric, interventional study on spontaneous vaginal clearance of Mycoplasma genitalium. The main objective is to evaluate the spontaneous vaginal clearance of M.
- Trial name
- MYCOCLEAR (NCT04841408)
- Testing
- Vaginal self-sampling
- Where
- France
- Volunteers
- 69 people
- Sponsor
- University Hospital, Bordeaux
Atrial Fibrillation
Effect of Diltiazem on Pharmacokinetics of BMS-914392
The purpose of this study is to assess the effects of diltiazem on the pharmacokinetics of single-dose BMS-914392 in healthy subjects.
- Trial name
- NCT01211808
- Testing
- BMS-914832, Diltiazem
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Bristol-Myers Squibb
Facial Nerve Palsy
Collagen Treatment in Facial Nerve Palsy
To test the effectiveness of a collagen-based treatment for patients complaining of long standing facial nerve axonotmesis, who are following a proprioceptive neuromuscular facilitation protocol (Kabat method), compared to a…
- Trial name
- NCT04353908
- Testing
- Rehabilitation, Collagen Injection
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Uniter Onlus
Parkinson Disease
Feasibility and Effects of a Pickleball Program for People With Parkinson Disease
Pickleball is a fast-growing sport that has been shown to improve social integration, life satisfaction, function, and cognitive function in older adults.
- Trial name
- NCT05994508
- Testing
- Pickleball program
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Midwestern University
Visual Acuity
2-week Evaluation of Marketed Silicone Hydrogel Contact Lenses in Indian Population
The primary objective of this study is to evaluate the clinical performance of two marketed silicone hydrogel contact lenses in an Indian population in the following areas: physiological characteristics, comfort characteristics…
- Trial name
- NCT02394808
- Testing
- senofilcon A, lotrafilcon B
- Where
- India
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Opioid Use
Investigation of the Effect of Intravenous Lidocaine Infusion on Postoperative Pain Treatment and Bowel Function in Robotic Bowel Surgery
Single center double blind randomised controlled trial. 60 subjects. Giving lidocaine IV or saline to patients due to robot assisted colorectal surgery. Primary outcome is cumulative morphine consumption at 24 hours.
- Trial name
- NCT03044808
- Testing
- Lidocaine, Saline
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- Odense University Hospital
Healthy Participants
A Study Assessing the Drug Levels, Drug Effects, and Safety of BMS-986322 in Healthy Participants
A Study assessing the drug levels and drug effects of variable doses of BMS-986322 in Healthy Participants compared to a placebo. The study also assesses how BMS-986322 affects the body with food and its acidity levels.
- Trial name
- NCT04175925
- Testing
- BMS-986322, famotidine
- Where
- United States
- Volunteers
- 171 people, healthy volunteers welcome
- Sponsor
- Bristol-Myers Squibb
Hemophagocytic Lymphohistiocytosis
Hybrid Immunotherapy for Hemophagocytic LymphoHistiocytosis
Despite good progress during the last decade, hemophagocytic lymphohistiocytosis (HLH) remains difficult to treat. Two different treatment regimens have been used successfully.
- Trial name
- NCT01104025
- Testing
- ATG, rabbit, Etoposide, Methotrexate
- Where
- 15 sites in United States, Canada
- Volunteers
- 31 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
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