Clinical trials: Experimental, completed
Cancer
Supersaturated Calcium Phosphate Oral Rinse (Caphosol®) For the Prevention of Oral Mucositis in Children Undergoing Chemotherapeutic Treatments
Prospective double-blinded randomized clinical study. Aim of the study is to compare the effectiveness of Caphosol mouth rinses in prevention of oral mucositis as compared to 0.9% NaCl rinses.
- Trial name
- NCT02807337
- Testing
- Caphosol, 0,9% NaCl
- Where
- 3 sites in Finland
- Volunteers
- 47 people
- Sponsor
- Tampere University Hospital
Scheduled General Anaesthesia With Airway Control
Effects of Drinking at PACU Discharge After General Anaesthesia With Airway Control on Aspiration, Vomiting and Patients Comfort
National guidelines about post-operative fasting after general anesthesia are missing. Current clinical practices are highly variable and no study has ever evaluated on a large scale the real risk of an early drinks recovery in…
- Trial name
- I-DRINC (NCT02193737)
- Testing
- Early oral fluid recovery., Delayed oral fluid recovery.
- Where
- France
- Volunteers
- 1,555 people
- Sponsor
- Poitiers University Hospital
Head and Neck Cancer, Radiation Toxicity
Salivary Gland Surgery Before Radiation Therapy in Preventing Radiation-Caused Xerostomia in Patients With Head and Neck Cancer
RATIONALE: Moving a salivary gland out of the area that will undergo radiation therapy may protect the gland from side effects of radiation therapy and may prevent xerostomia (dry mouth).
- Conditions
- Head and Neck Cancer, Radiation Toxicity, Xerostomia
- Trial name
- NCT00068237
- Testing
- salivary gland transfer, Post-operative radiation therapy
- Where
- 12 sites in United States, Canada
- Volunteers
- 49 people
- Sponsor
- Radiation Therapy Oncology Group
Rheumatoid Arthritis
Development of a Normative Database for Rheumatoid Arthritis (RA) Imaging With Tc99m Tilmanocept
This study will establish a normative database of Tilmanocept Uptake Values (TUVjoint) in healthy controls age-matched to the RA population.
- Trial name
- NCT04947137
- Testing
- Tc99m tilmanocept
- Where
- 7 sites in United States
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Navidea Biopharmaceuticals
Multiple Myeloma
Study Evaluating Safety, Tolerability and Clinical Activity of GSK2857916 in Combination With Pembrolizumab in Subjects With Relapsed/Refractory Multiple Myeloma (RRMM)
This is a phase I/II, single arm, open label, two-part study that will assess safety, tolerability and clinical activity of GSK2857916 given in combination with a programmed cell death-1 (PD-1) inhibitor pembrolizumab in subjects…
- Trial name
- DREAMM 4 (NCT03848845)
- Testing
- belantamab mafodotin, Pembrolizumab
- Where
- 12 sites in United States, Canada and 2 more
- Volunteers
- 41 people
- Sponsor
- GlaxoSmithKline
ASD
Internal Versus External Attentional Focus in Gross- and Fine-Motor Learning Among Children With Autism Requiring Ongoing Everyday Support
This study examined how different attentional focus instructions affect motor learning in children with autism spectrum disorder (ASD).
- Trial name
- NCT07851272
- Testing
- External Focus of Attention Instructions, Internal Focus of Attention Instructions
- Where
- Israel
- Volunteers
- 10 people
- Sponsor
- University of Haifa
Chronic Obstructive Pulmonary Disease, COPD
Tele Health Monitoring Service for Patients With Chronic Obstructive Pulmonary Disease
The aim of this study is to evaluate the effect of monitoring patients with chronic obstructive pulmonary disease (COPD) after a hospitalization for COPD exacerbation or pneumonia.
- Trial name
- NCT02615795
- Testing
- Tele Monitoring, using Tunstall monitoring device
- Where
- Denmark
- Volunteers
- 160 people
- Sponsor
- University of Aarhus
Alopecia Areata
Follicular Revival in Treatment-resistant Alopecia Areata: Evaluating Use of Micro-needling
The investigators propose to study the efficacy of micro-needling via the SOL Nova Device in generating hair growth in patients with Alopecia Areta (AA) who are either non-responsive or only partially responsive to combination…
- Trial name
- NCT04338295
- Testing
- Tattoo machine (SOL Nova Device)
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Yale University
Self Confidence, Knowledge, Attitudes, Practice
The Effect of a Web-based Simulation Application
Cardiopulmonary resuscitation (CPR) training for nursing students is important. The importance of using computer-assisted simulation in gaining skills for basic life support applications is increasing.
- Conditions
- Self Confidence, Knowledge, Attitudes, Practice, Satisfaction
- Trial name
- NCT05580939
- Testing
- Intervention group
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Duzce University
Stroke
Interactive Intention-Driven Upper-Limb Training Robotic System
The goal of this study is to determine robotic hand system is more effective than conventional physical and occupational therapy at promoting functional recovery of the affected arm in subjects after stroke.
- Trial name
- NCT02077439
- Testing
- Hand Robotic Training, Hand and Arm Robotic Training, Conventional therapy
- Where
- Hong Kong
- Volunteers
- 70 people
- Sponsor
- The Hong Kong Polytechnic University
Healthy
Study to Assess the Effects of Esketamine on Safety of On-road Driving in Healthy Participants
The purpose of this study is to evaluate the effect of esketamine compared to placebo on driving performance as assessed by the mean difference of standard deviation of lateral position (SDLP) from an on-road driving test in…
- Trial name
- DRiVESaFe (NCT02228239)
- Testing
- Esketamine, Mirtazapine
- Where
- Netherlands
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Janssen Research & Development, LLC
Cancer, Injury of Liver
Implementing Online Patient-Provider Communication Into Clinical Practice
This interdisciplinary, international collaboration study, including the the Norwegian Health Economy Administration (HELFO) will evaluate the effectiveness and real-world implementation of an online patient-provider…
- Conditions
- Cancer, Injury of Liver, Diabetes
- Trial name
- OPPC (NCT00971139)
- Testing
- Access to an OPPC service
- Where
- Norway
- Volunteers
- 199 people
- Sponsor
- Oslo University Hospital
Adult Skin Healthy Signs
An 8-week Full Face HUT Clinical Trial for HydroBoost (2.0/3.0)
To investigate the product regiments' performance on moisturization related skin healthy signs (skin moisturization, barrier function, elasticity, translucency, roughness and skin conditions) through instrumental evaluation…
- Trial name
- NCT03264677
- Testing
- Group 1, Group 2, Group 3
- Where
- China
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Pte Ltd
Parkinson Disease, Weight-Lifting Exercise Program
Daily Undulating Periodization Methods With Parkinson's Disease
Compare periodized (cyclic) resistance training with and without motor training specific to activities of daily living.
- Trial name
- NCT03867877
- Testing
- Periodized training with motor practice, Simple Periodized Training
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- University of Miami
Cerebral Palsy
Virtual Reality Therapy and Transcranial Direct Current Stimulation in Cerebral Palsy.
A double-blinded randomized controlled crossover trial will be conducted, and all participants will undertake non-immersive VR tasks and tDCS-active or tDCS-sham.
- Trial name
- NCT04044677
- Testing
- tDSC-active
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- University of Sao Paulo
Seborrheic Keratosis
A Randomized, Double-Blind, Vehicle-Controlled Study in Subjects With Seborrheic Keratosis
This is a randomized, double-blind, vehicle-controlled, parallel group study.
- Trial name
- SK (NCT02667275)
- Testing
- A-101 Solution, Vehicle Solution
- Where
- United States
- Volunteers
- 487 people
- Sponsor
- Aclaris Therapeutics, Inc.
Quality of Life, Oesophageal Cancer
Quality of Life After Oesophageal or Gastric Cancer Surgery
This study aim to assess quality of life of patients 0-5 years after oesophageal or gastric cancer surgery and to develop and test an information and support program aiming to enhance the patients quality of life (QOL) after…
- Conditions
- Quality of Life, Oesophageal Cancer, Gastric Cancer
- Trial name
- NCT01657175
- Testing
- Supportive care
- Where
- Sweden
- Volunteers
- 82 people
- Sponsor
- Region Skane
Tinnitus
Hearing Aids With "Notched Amplification" for the Treatment of Chronic Tinnitus
Pilot study on safety, tolerability and clinical performance/randomized double-blind active-controlled pilot-study. Patients are being recruited from patients of the Tinnitus Center of Regensburg and groupwise randomized.
- Trial name
- NoA-Tin (NCT02408575)
- Testing
- Notched filtering (verum)
- Where
- Germany
- Volunteers
- 44 people
- Sponsor
- University of Regensburg
Burnout, Professional
Better Together Physician Coaching: Mitigating Burnout in UME
Better Together Physician Coaching ("Better Together", or "BT"), a 4-month, web-based positive psychology multimodal coaching program was built to decrease burnout in medical trainees.
- Trial name
- BT for UME (NCT05822375)
- Testing
- Better Together Physician Coaching
- Where
- United States
- Volunteers
- 490 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Postural Balance
NMES to Improve Hip Abductor Strength and Balance
This study will examine the addition of neuromuscular electrical stimulation (NMES) on the hip abductors during strength training and a fall prevention program for improving muscle strength and improving balance.
- Trial name
- IMAGINE+NMES (NCT02992275)
- Testing
- Neuromuscular electrical stimulation (NMES), Multi-Modality Balance Intervention (MMBI)
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Baltimore VA Medical Center
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