Clinical trials: Experimental, completed
Acute Coronary Syndrome
Secondary Prevention of coRonary Events After Discharge From Hospital (SPREAD)
This is a randomized, open trial comparing post discharge interventions by community health workers (CHW) to standard care in acute coronary syndrome (ACS) patients.
- Trial name
- SPREAD (NCT01207700)
- Testing
- CHW based intervention post ACS
- Where
- 13 sites in India
- Volunteers
- 806 people
- Sponsor
- St. John's Research Institute
Depression, Anxiety
Effects of MSC Intervention on the Dyadic Mental Health of Lung Cancer Patients and Their Caregivers
The incidence and mortality of lung cancer ranks first among cancers in the world, and the five-year survival rate of lung cancer patients is only 15% to 30%.
- Trial name
- NCT04795700
- Testing
- MSC intervention
- Where
- China
- Volunteers
- 36 people
- Sponsor
- Central South University
Alcohol Dependence
Neurofeedback & Alcohol Dependence
The study aims to examine whether the neurofeedback method (based on functional magnetic resonance imaging [fMRI]) can help patients with alcohol dependence to control their urges to drink alcohol and thus to remain abstinent.
- Trial name
- NCT02486900
- Testing
- fMRI-based neurofeedback
- Where
- United Kingdom
- Volunteers
- 52 people
- Sponsor
- Cardiff University
HIV-1 Infection
Study to Evaluate the Safety and Efficacy of Switching From Regimens Consisting of Boosted Atazanavir or Darunavir Plus Either Emtricitabine/Tenofovir or Abacavir/Lamivudine to Bictegravir/Emtricitabine/Tenofovir Alafenamide in Virologically Suppressed HIV-1 Infected Adults
The primary objective of this study is to evaluate the efficacy of switching to a fixed-dose combination (FDC) of bictegravir/emtricitabine/tenofovir alafenamide (B/F/TAF) versus continuing on a regimen consisting of boosted…
- Trial name
- NCT02603107
- Testing
- RTV, ATV, DRV
- Where
- 119 sites in United States, Australia and 9 more
- Volunteers
- 578 people
- Sponsor
- Gilead Sciences
Solid Tumor
Clinical Study of Utidelone Injection in Patients With Advanced or Metastatic Solid Tumors
This trial is an open, two-stage, multi-center, phase II clinical trial to evaluate the efficacy and safety of Utidelone in advanced solid tumors (excluding breast cancer, lung cancer, and colorectal cancer) that have failed…
- Trial name
- NCT04911907
- Testing
- utidelone injection
- Where
- 3 sites in China
- Volunteers
- 126 people
- Sponsor
- Beijing Biostar Pharmaceuticals Co., Ltd.
Nail Diseases
Use of Platelet-rich Plasma (PRP) Therapy in Patients With Brittle Nail Syndrome
The purpose of this study is to assess the efficacy and safety of platelet-rich plasma therapy for brittle nail syndrome
- Trial name
- NCT04941807
- Testing
- Platelet-rich plasma, Platelet-poor plasma
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Weill Medical College of Cornell University
Hypercholesterolemia
The Efficacy and Safety of Atorva® 20mg Versus Lipitor® 20mg
The generic formulation of atorvastatin (Atorva®) 20mg was not inferior to the branded formulation of atorvastatin (Lipitor®) 20mg in this 8-week treatment of hyperlipidemic Korean patients.
- Trial name
- NCT01624207
- Testing
- generic formulation of atorvastatin (Atorva®), branded formulation of atorvastatin (Lipitor®)
- Where
- South Korea
- Volunteers
- 376 people
- Sponsor
- Seoul National University Hospital
Multiple Myeloma
An Open-label, Dose Escalation Study in Japanese Participants With Relapsed/Refractory Multiple Myeloma Who Have Failed Prior Anti Myeloma Treatments
Belantamab mafodotin (GSK2857916) is a first in class, antibody dependent cellular cytotoxicity (ADCC) enhanced, humanized immunoglobulin G1 (IgG1) antibody-drug conjugate (ADC) which binds specifically to B cell maturation…
- Trial name
- NCT03828292
- Testing
- Belantamab mafodotin, Bortezomib, Dexamethasone
- Where
- 4 sites in Japan
- Volunteers
- 15 people
- Sponsor
- GlaxoSmithKline
Cancer
Palliative Care Yields Cancer Wellbeing Support
The goal of this study is to evaluate the effectiveness of a programme for transitional palliative cancer care (Pal-Cycles) in seven countries (the Netherlands, Germany, United Kingdom, Hungary, Poland, Romania and Portugal) and…
- Trial name
- Pal-Cycles (NCT06259136)
- Testing
- A transitional palliative care intervention
- Where
- Netherlands
- Volunteers
- 515 people
- Sponsor
- Radboud University Medical Center
Mental Fatigue
Mindfulness, Mental Fatigue, Inhibitory Control and Endurance Performance in Athletes
This study investigated whether trait mindfulness in athletes is associated with impairments in neurocognitive function and endurance performance resulting from mental fatigue.
- Trial name
- NCT05466136
- Testing
- Mental fatigue condition, Control condition
- Where
- Taiwan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- National Taiwan Normal University
Colorectal Polyp
Compare Bleeding Risk Between Cold and Hot Snaring Polypectomy for Small Colorectal Polyp: a Randomized Control Trial
In this randomized control trial the investigators aim to compare the bleeding complication between cold snaring and hot snaring polypectomy with a large sample size.
- Trial name
- NCT03373136
- Testing
- Polypectomy
- Where
- Taiwan
- Volunteers
- 4,270 people
- Sponsor
- National Taiwan University Hospital
Diabetes Mellitus, Type 2, Home Visit
Home-Based Intervention to the Diabetics
Why is the research needed? This study reflects the complexity of the process that patients with diabetes are experiencing when staying at home away from the supervision of health professionals.
- Trial name
- NCT04104711
- Testing
- Home visits, health education
- Volunteers
- 81 people
- Sponsor
- Dilay AÇIL,PhD
Autism Spectrum Disorder
Social Groups for Australian Children on the Autism Spectrum
This study evaluates the KONTAKT social skills group training in Australian children on the autism spectrum compared to an active control group which is a group Art class
- Trial name
- NCT04024111
- Testing
- KONTAKT(c), Art group
- Where
- Australia
- Volunteers
- 84 people
- Sponsor
- Curtin University
Cancer
Implementation and Evaluation of Dignity Therapy in Denmark
The purpose of the study is to investigate whether Danish patients with incurable cancer have a need of, interest in and benefit from Dignity Therapy.
- Trial name
- DignityDK (NCT01507571)
- Testing
- Dignity Therapy
- Where
- 2 sites in Denmark
- Volunteers
- 80 people
- Sponsor
- Bispebjerg Hospital
Amyotrophic Lateral Sclerosis (ALS)
Remotely Supervised tDCS for Slowing ALS Disease Progression
Most ALS care is centered on patient support and symptom management, making rehabilitation an integral aspect for slowing disease progression, prolonging life span, and increasing quality of life.
- Trial name
- NCT04866771
- Testing
- Transcranial Direct Current Stimulation (tDCS)
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of Illinois Chicago
Stroke, Upper-limb Paresis
Automatic Versus Intentional Movement Exercises to Enhance Arm Functions After Stroke
Many patients retain upper-limb motor impairment following stroke. Most conventional rehabilitation techniques are aimed to improve motor intentional movement by repeated exercises.
- Trial name
- AUTOTAB (NCT01565044)
- Testing
- motor training
- Where
- France
- Volunteers
- 26 people
- Sponsor
- Hospices Civils de Lyon
Aging
Fit & Active Seniors Trial
The investigators propose to test the hypothesis that a six-month intervention of combined fitness and cognitive training in the form of dancing will have a significant positive effect on a variety of executive control and memory…
- Trial name
- FAST (NCT01472744)
- Testing
- Dance Group, Strength, Stretching, Stability, Walking
- Where
- United States
- Volunteers
- 247 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign
Feasibility Studies
An HIV Status-neutral Microeconomic Intervention
The aim is the current study is to establish feasibility and acceptability of the SeCuRE intervention to improve HIV prevention and care continua outcomes. To meet this aim, the study has the following objectives: 1.
- Trial name
- Secure (NCT06212544)
- Testing
- Immediate Intervention, Delayed Intervention
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Road Traffic Injury Prevention, Motorcycle Safety, Personal Protective Equipment Use, Visibility Materials, Injury Prevention Education, Health Behavior Change
The Effectiveness of Health Education Intervention in Enhancing Personal Protective Equipment Use
This study is testing whether a health education program can help commercial motorcycle riders and passengers in the Limbe and Tiko Health Districts of Cameroon improve their use of safety equipment.
- Trial name
- NCT07087444
- Testing
- Health education intervention to improve knowledge and uptake of personal protective equipment and visibility materials among commercial motorcycle riders and passengers
- Where
- Cameroon
- Volunteers
- 967 people, healthy volunteers welcome
- Sponsor
- University of Buea
COVID-19 Pneumonia
Influence of Manual Diaphragm Release on Pulmonary Functions in Women With COVID-19
Manual noninvasive respiratory techniques gained interest to treat respiratory pathologies related to COVID 19. This study designed to determine the combined effect of manual diaphragmatic release technique with the effect of…
- Trial name
- NCT05903144
- Testing
- manual therapy, breathing exercise and prone position alone
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
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