Clinical trials: Experimental Group
Quality of Life, Postoperative Complications
Low Pressure Pneumoperitoneum and Deep Neuromuscular Block vs. Standard During RARP to Improve Quality of Recovery; a Randomized Controlled Study.
Intra-abdominal pressure (IAP) needed to create sufficient workspace during laparoscopic surgery affects the surrounding organs with ischemia-reperfusion injury and a systemic immune response.
- Conditions
- Quality of Life, Postoperative Complications, Acute Pain, Immune System Tolerance
- Trial name
- RECOVER-2 (NCT04250883)
- Testing
- Low intra-abdominal pressure, Deep neuromuscular blockade (NMB), Standard intra-abdominal pressure
- Where
- Netherlands
- Volunteers
- 97 people
- Sponsor
- Radboud University Medical Center
Amyloidosis
The Study of an Investigational Drug, Patisiran (ALN-TTR02), for the Treatment of Transthyretin (TTR)-Mediated Amyloidosis in Participants Who Have Already Been Treated With ALN-TTR02 (Patisiran)
The purpose of this study is to evaluate the safety and efficacy of long-term dosing with ALN-TTR02 (patisiran) in participants with transthyretin (TTR) mediated amyloidosis (ATTR).
- Trial name
- NCT02510261
- Testing
- Patisiran
- Where
- 56 sites in United States, Argentina and 19 more
- Volunteers
- 211 people
- Sponsor
- Alnylam Pharmaceuticals
Respiratory Syncytial Virus Infections
Safety and Reactogenicity Study of GlaxoSmithKline (GSK) Biologicals' Investigational Respiratory Syncytial Virus (RSV) Vaccine (GSK3003891A) in Healthy Women
The purpose of this study is to assess the safety and reactogenicity of a single intramuscular dose of GSK Biologicals' investigational RSV vaccine, in healthy, non-pregnant women aged 18 to 45 years.
- Trial name
- NCT02753413
- Testing
- RSV vaccine GSK3003891A, Boostrix
- Where
- Belgium
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Infant, Low Birth Weight
Household Air Pollution and Health: A Multi-country LPG Intervention Trial
This study is a randomized controlled trial of liquefied petroleum gas (LPG) stove and fuel distribution in 3,200 households in four countries (India, Guatemala, Peru, and Rwanda).
- Trial name
- HAPIN (NCT02944682)
- Testing
- Liquefied petroleum gas (LPG) cookstove
- Where
- 4 sites in Guatemala, India and 2 more
- Volunteers
- 6,704 people
- Sponsor
- Emory University
Procedural Pain
Crochet Octopus in The Process of Heel Lance in Neonates
The main objective of the study was to determine the effect of using crochet octopus in order to reduce the acute pain developed during the process of heel lance in neonates.
- Trial name
- NCT04560374
- Testing
- crochet octopus
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Marmara University
Traumatic Brain Injury, Post-Traumatic Stress Disorder
Executive Functioning in TBI From Rehabilitation to Social Reintegration: COMPASS
Interventional, controlled clinical trial with two arms, 110 Veterans with TBI and PTSD
- Trial name
- COMPASS (NCT01816061)
- Testing
- Experimental - COMPASS, Control - COMPASS
- Where
- United States
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Alzheimer Disease, Dementia
STAR Caregivers - Virtual Training and Follow-up
This study evaluates the effectiveness of a caregiver outreach, training, and support program for caregivers of people with dementia who are using antipsychotic medication to manage agitation/aggression.
- Conditions
- Alzheimer Disease, Dementia, Caregiver Burnout
- Trial name
- STAR-C-VTF (NCT04271046)
- Testing
- STAR-C-VTF, Control
- Where
- United States
- Volunteers
- 67 people
- Sponsor
- Kaiser Permanente
Skin Cancer
Evaluation of Adherence to Topical Agents: Applying Communication Technology to Improve Sunscreen Use
The purpose of this study is to determine if using an electronic reminder improves adherence to sunscreen use. The specific study aims are as follows: 1.
- Trial name
- NCT00535769
- Testing
- Electronic + no text message, Electronic monitor + text messages
- Where
- 2 sites in United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Fibroids
Uterine Filling Pressure in Hysteroscopy
The aim of the study is to compare the outcomes of patients undergoing hysteroscopy with a MyoSure device with a pressure of 60 mmHg to those using the standard of 80 mmHg.
- Trial name
- NCT04550429
- Testing
- MyoSure Hysteroscopic Morcellator Device
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Northwestern University
Gustilo-Anderson Type III Open Tibia Fracture
Randomized Trial Comparing Irrisept to Saline Irrigation for Infection Prevention
Early debridement and definitive fixation, at the initial operative setting, historically led to no difference in the infection rates for Gustilo-Anderson type III open tibia fractures. However, Lenarz et al.
- Trial name
- NCT05402995
- Testing
- Irrisept (Irrigation Solution), Saline
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Brett D. Crist
Chickenpox
A Study on the Immune Response and Safety of Various Potencies of an Investigational Chickenpox Vaccine Compared With a Marketed Chickenpox Vaccine, Given to Healthy Children 12 to 15 Months of Age
The purpose of this study is to assess immune response and safety of various potencies of an investigational chickenpox vaccine given to healthy children 12 to 15 months of age.
- Trial name
- NCT05084508
- Testing
- Investigational varicella vaccine low potency, Investigational varicella vaccine medium potency, Investigational varicella vaccine high potency
- Where
- 51 sites in United States, Estonia and 4 more
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Latent Cancer (Prostate)
Impact on Instructional Video on Patients' Compliance With Preparation During CT Planning for Prostate Cancer
Rectal toxicity limits dose escalated intensity modulated radiotherapy (IMRT) for prostate cancer. The dose volume constraints that predict for rectal toxicity require minimizing prostate motion and rectum and bladder filling of…
- Trial name
- NCT02410291
- Testing
- Educational video
- Where
- Canada
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre
Obesity, Sarcopenia
Biological Effects of Weight Loss In Older, Obese Women
Obesity and sedentary lifestyle are associated with physical impairments and biological changes in older adults. Weight loss combined with exercise may reduce inflammation and may improve physical functioning in older adults who…
- Trial name
- WL+E (NCT01032733)
- Testing
- Lifestyle Counseling, Educational Control
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Florida
Mild Cognitive Impairment
Effect of Action Observation Training on Gait Variables and Global Cognitive Functions
This study will investigate the effect of Action Observation Teaining (AOT) on gait variables and global cognitive functions in older adults with mild cognitive impairment (MCI).
- Trial name
- NCT03522389
- Testing
- AOT with gait training, Gait training, Education
- Where
- Thailand
- Volunteers
- 39 people
- Sponsor
- Mahidol University
Treatment of Early Pulmonary Infections With P. Aeruginosa in Cystic Fibrosis Patients
Randomized, Controlled Study of CF Patients Between 3 Months and Less Than 7 Years
This study investigated the efficacy of inhaled TOBI treatment for early infections of P. aeruginosa in paediatric patients with cystic fibrosis.
- Trial name
- EARLY (NCT01082367)
- Testing
- TOBI
- Where
- 19 sites in Canada, Egypt and 8 more
- Volunteers
- 50 people
- Sponsor
- Novartis Pharmaceuticals
Bladder Cancer
Comparison of Nerve Stimulating Approach and Interfascial Injection Approach During Sono-guided Obturator Nerve Block
Transurethral resection of bladder tumor (TURB) has been essential treatment for bladder tumours. Direct electrical stimulation of an obturator nerve during the TURB procedures can trigger an inadvertent adductor muscle spasm…
- Trial name
- NCT02452944
- Testing
- nerve stimulator (stimuplex HNS12), ultrasound
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Gachon University Gil Medical Center
Postoperative Pain
Magnesium Sulfate for Analgesia in Pediatric Transplant
To use magnesium sulfate as adjuvant analgesia by implementing a treatment protocol in order to determine whether can benefit pediatric pain in post-operative transplanted patients and decrease overall opioid consumption.
- Trial name
- NCT04812028
- Testing
- Magnesium sulfate
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- University of Minnesota
Respiratory Syncytial Virus Infections
Immunogenicity, Safety, Reactogenicity and Persistence of an Investigational Respiratory Syncytial Virus (RSV) Vaccine in Adults Aged 60 Years and Above
The purpose of this study is to assess the safety, reactogenicity, immunogenicity and long-term persistence of immune response up to 5 years following a single dose vaccination of GSK's investigational vaccine RSVPreF3 OA, in…
- Trial name
- NCT04732871
- Testing
- RSVPreF3 OA investigational vaccine
- Where
- 46 sites in United States, Finland and 3 more
- Volunteers
- 1,720 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Central Auditory Processing Disorder, Traumatic Brain Injury
Central Auditory Processing Disorders Associated With Blast Exposure
The incidence of central auditory dysfunction in war fighters who are exposed to high-explosive blasts while serving in combat have not been clearly determined.
- Conditions
- Central Auditory Processing Disorder, Traumatic Brain Injury, Hearing Loss
- Trial name
- NCT00554801
- Testing
- Audiological testing
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Migraine, Episodic Migraine
Study of Two Digital Therapeutics for the Prevention of Episodic Migraine
Randomized study of two digital therapeutics for the prevention of episodic migraine
- Conditions
- Migraine, Episodic Migraine, Headache, Headache, Migraine
- Trial name
- ReMMi-D (NCT05853900)
- Testing
- ReMMi-D Digital Therapeutic
- Where
- United States
- Volunteers
- 568 people
- Sponsor
- Click Therapeutics, Inc.
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.