Clinical trials: Experimental Group
Type 2 Diabetes Mellitus With Complication
Canagliflozin on Liver Inflammation Damage in Type 2 Diabetes Patients With Nonalcoholic Fatty Liver Disease
Type 2 diabetes mellitus (T2DM) is always accompanied with nonalcoholic fatty liver disease (NAFLD).This prospective, randomized controlled intervention study was designed to reveal the potential clinical application and…
- Trial name
- NCT05422092
- Testing
- Canagliflozin, Pioglitazone
- Volunteers
- 80 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Pain, Ecchymosis
Effect of Hypericum Perforatum Oil on Ecchymosis and Pain
Low molecular weight heparin is a drug with anticoagulant and antithrombotic effects. This drug is frequently administered subcutaneously to patients by nurses.
- Trial name
- NCT06367036
- Testing
- Topical hypericum perforatum oil intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people
- Sponsor
- Uskudar University
Missing Tooth, Osseointegration Failure of Dental Implant
X-space Implants in Post-extraction Sites.
Several recent systematic reviews have highlighted how the macrodesign of dental implants can influence stress distribution and biomechanical and biological behavior in implants immediately inserted in post-extraction sites.
- Trial name
- NCT04492111
- Testing
- post-extraction dental implant
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Bari
Ceramic Restorations in Endodontically Treated Teeth
Endocrowns vs.Ceramic Onlays Used in Endodontically Treated Teeth- Randomized Clinical Study
Objective: To evaluate the immediate and mediate outcomes of endocrowns and onlay ceramic restorations with glass fiber pin in endodontically treated teeth.
- Trial name
- NCT03064516
- Testing
- Endocrown, Onlay and fiber pin
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Susana Morimoto
Crowding of Anterior Mandibular Teeth
SmartArch vs Super Elastic NiTi Aligning Archwires
This study is intended primarily to compare the alignment efficiency and rate of two different types of archwires that are used in the first stage of orthodontic treatment , also addressing pain and root resorption that may be…
- Trial name
- NCT05510206
- Testing
- Leveling and alignment
- Where
- Iraq
- Volunteers
- 40 people
- Sponsor
- University of Baghdad
Lumbar Disc Herniation
Clinical Research on the Efficacy of Bosinji on Herniated Intervertebral Disc of Lumbar Spine
This randomized controlled clinical trial is designed to evaluate the efficacy and safety of Bosinji on low back pain and radiating pain of lumbar herniated intervertebral disc (L-HIVD) by assessing pain, function, and quality of…
- Trial name
- NCT03386149
- Testing
- Bosinji, Loxonine tab., Acupuncture
- Where
- 4 sites in South Korea
- Volunteers
- 74 people
- Sponsor
- Kyunghee University Medical Center
Shoulder Pain, Myofascial Pain Syndrome
Intratissue Percutaneous Electrolysis vs Dry Needling in Myofascial Pain Syndrome of Shoulder Pain
This is a parallel-group randomised clinical trial: Primary purpose: To analyse the clinical changes produced by two different physiotherapy treatments (Intratissue Percutaneous Electrolysis and Dry Needling) for myofascial…
- Trial name
- NCT05593848
- Testing
- Intratissue Percutaneous Electrolysis, Dry Needling
- Where
- Spain
- Volunteers
- 42 people
- Sponsor
- University of Salamanca
Spondylolisthesis
Efficacy of Hybrid Systems in Comparison to the Rigid Spondylodesis in Lumbar-spine Fusion
This study is designed as a randomized, parallel-group, therapy-controlled trial in a clinical care setting at a university hospital.
- Trial name
- D-Rod (NCT01852526)
- Testing
- Experimental: hybrid system, Active Comparator: Plif
- Where
- 2 sites in Germany
- Volunteers
- 5 people
- Sponsor
- University of Cologne
COPD
Effect of Combined Endurance Training on ADL and Walking in COPD Patients
Chronic Obstructive Pulmonary Disease (COPD) is a chronic disease with related exercise intolerance and marked disability due to symptoms such as dyspnea and fatigue.
- Trial name
- NCT05708443
- Testing
- LL group, L+UL group
- Where
- 3 sites in Italy
- Volunteers
- 36 people
- Sponsor
- Istituti Clinici Scientifici Maugeri SpA
Asthma in Children
The Effect of 10-Week Exercise Training on Children With Asthma
The goal of this research is to determine whether 10-weeks of exercise training can benefit asthmatic children and young adults with a history of exercise-induced bronchoconstriction (EIB).
- Trial name
- NCT03716219
- Testing
- Exercise Training
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, Irvine
Embolism and Thrombosis, Anticoagulation
Prolonged Anticoagulation Therapy on the Prognosis of Patients With Left Ventricular Thrombosis
A single-center, open-label, exploratory randomized controlled study is proposed with the following objectives: whether prolonging the duration of anticoagulation to 12 months, compared with 6 months of routine anticoagulation…
- Trial name
- NCT06209892
- Testing
- Extended anticoagulation
- Volunteers
- 220 people
- Sponsor
- Chinese Academy of Medical Sciences, Fuwai Hospital
Postoperative Delirium
The Effect of Bupivacaine Liposome Preemptive Analgesia on Postoperative Pain and Delirium in Elderly Patients Undergoing Hip Fracture Surgery
To explore the effects of bupivacaine liposomes in preemptive analgesia for iliofascial block on postoperative pain and postoperative delirium in elderly patients with hip fractures, to optimize perioperative analgesia…
- Trial name
- NCT07066111
- Testing
- Tramadol, bupivacaine liposome (ultrasound-guided high iliofascial space block)
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Healthy Adult Participants, Crossfit
Effect of the Ultrasound-guided Percutaneous Neuromodulation on the Mean Velocity in Crossfit Practitioners.
This randomized controlled blinded clinical trial aims to evaluate the effect of ultrasound-guided percutaneous neuromodulation (US-guided PNM) targeting the innervation of the transversus abdominis muscle on squat performance in…
- Trial name
- NCT07684534
- Testing
- ultrasound-guided percutaneous neuromodulation
- Where
- Spain
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- CEU San Pablo University
Stoma - Ileostomy, High Output Stoma
Study of Treatment With Intensified Omeprazole Treatment to Prevent High Output Stoma 1
The goal of this clinical trial is to evaluate if intensified omeprazole therapy can reduce high-output stoma (HOS) in adults undergoing ileostomy formation surgery.
- Conditions
- Stoma - Ileostomy, High Output Stoma, Colon Cancer, IBD (Inflammatory Bowel Disease)
- Trial name
- STOP-HOS-1 (NCT06917963)
- Testing
- Intensified intravenous omeprazole therapy (loading dose 80 mg IV, then 40 mg IV twice daily at 6:00 AM and 6:00 PM), Standard intravenous omeprazole therapy (40 mg IV once daily at 6:00 AM).
- Where
- 2 sites in Poland
- Volunteers
- 80 people
- Sponsor
- Medical University of Gdansk
Metabolic Syndrome, Dyslipidemia
Impact of Consumption of Beta-glucans on the Intestinal Microbiota and Glucose and Lipid Metabolism
The purpose of this study is to investigate if daily consumption of barley beta-glucans effect lipid and glucose metabolism and alter intestinal microbiota composition in participants with metabolic syndrome or with high risk for…
- Conditions
- Metabolic Syndrome, Dyslipidemia, Obesity, Abdominal, Hyperglycemia
- Trial name
- NCT02041104
- Testing
- Bread with added beta-glucans
- Where
- 3 sites in Slovenia
- Volunteers
- 51 people
- Sponsor
- Mlinotest Zivilska Industrija d.d.
Acute Lymphoblastic Leukemia
Effect of Metformin on ABCB1 and AMPK Expression in Adolescents With Newly Diagnosed Acute Lymphoblastic Leukemia
Acute lymphoblastic leukemia, is the most frequent cancer in children and adolescents. Some genes have been described to produce drug resistance, as ABCB1 probably by lack of activation of AMPK.
- Trial name
- NCT05326984
- Testing
- Metformin
- Where
- Mexico
- Volunteers
- 20 people
- Sponsor
- Hospital General de Mexico
Healthy Subjects
Safety and Pharmacokinetics Study of Multiple Ascending Doses and Food Effect of LV232 Capsules
This study is divided into two parts: the safety, tolerability, pharmacokinetic profiles of LV232 capsules after multiple ascending doses (hereinafter referred to as "PK characteristics of multiple ascending doses study ") and…
- Trial name
- NCT06279533
- Testing
- LV232
- Where
- China
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Vigonvita Life Sciences
Sexual Dysfunction
Motivational Interviews With Women Experiencing Sexual Dysfunction During Menopause Period
The aim of this study is to evaluate the effect of motivational interviews with women who experience sexual dysfunction during menopause on sexual quality of life and self-efficacy.The population of the study consisted of…
- Trial name
- NCT06337058
- Testing
- Experimental group (motivational interview)
- Where
- Turkey (Türkiye)
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- Hülya KAMALAK
Myocardial Infarction
Acute Myocardial Infarction With HyperOxemic Therapy II (AMIHOT II)
To determine whether or not HyperOxemic therapy rendered to patients (that meet the study inclusion criteria) with anterior acute myocardial infarction < 6 hours from symptom onset to reperfusion, results in a significant…
- Trial name
- AMIHOT II (NCT00175058)
- Testing
- AO Therapy (aqueous oxygen)
- Where
- United States
- Volunteers
- 317 people
- Sponsor
- TherOx
Hiv, Transgenderism
Drug-Drug Interaction Study in Trans Women Living With HIV
Introduction: Transgender (trans) women have been found to be at higher risk of and to be disproportionally affected by HIV. Trans women with HIV have also been found to have low usage and adherence rates to antiretroviral…
- Trial name
- T-DDI (NCT05663892)
- Testing
- Biktarvy 50/200/25 Tab, Estradiol Tablets
- Where
- Canada
- Volunteers
- 45 people
- Sponsor
- Maple Leaf Research
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.