Clinical trials: Experimental Group
Dementia, Alzheimer Disease
Effects of a Multicomponent Exercise Intervention on Physical and Cognitive Function of Older Adults With Dementia
Dementia is a leading cause of death and disability that was declared as one of the greatest health and social care challenges of the 21st century.
- Conditions
- Dementia, Alzheimer Disease, Vascular Dementia, Neurocognitive Disorders
- Trial name
- Body&Brain (NCT04095962)
- Testing
- Exercise
- Where
- Portugal
- Volunteers
- 110 people
- Sponsor
- Universidade do Porto
Headache
Lokal Cold Application in Nitroglycerin-Induced Headache (NIH)
The study was planned to evaluate the effect of local cold application on headache severity in individuals who received intravenous nitroglycerin treatment, which mostly causes headache due to its vasoditator effect.
- Trial name
- NCT04707586
- Testing
- Cold Application
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Yasemin Kalkan Uğurlu
Pancreatic Neoplasms
Clinical Efficacy of QYHJ and Standard Chemotherapy in the Treatment of Advanced Pancreatic Cancer
This prospective, multicenter, randomized, double-blind, placebo-controlled phase 3 trial included adults with histologically or cytologically confirmed stage IV pancreatic ductal adenocarcinoma who were eligible for…
- Trial name
- NCT05840341
- Testing
- QingyiHuaji optimized formula
- Where
- 4 sites in China
- Volunteers
- 305 people
- Sponsor
- Fudan University
Prediabetes
Role of Slowly Digesible Starch on Diabetes Risk Factors
The purpose of this study is to determine the effect of a slowly digesting starch on gut bacteria, sugar and fat metabolism, hunger hormones, and body fat in people with pre-diabetes.
- Trial name
- STARCH (NCT01708694)
- Testing
- Amylose, Amylopectin
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- Pennington Biomedical Research Center
MRI Imaging
Assessment of Investigational Magnetic Resonance Imaging and Post-Processing Procedures
The goals of this study are to (1) develop and optimize MRI acquisition and post-processing techniques and (2) to generate preliminary and comparative data on sequences for potential clinical trials.
- Trial name
- NCT03490656
- Testing
- MRI Scan - in addition to standard of care, MRI Scan - not in addition to standard of care
- Where
- United States
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- University of Cincinnati
Primary Biliary Cirrhosis
Mesenchymal Stem Cell Transplantation for Refractory Primary Biliary Cholangitis
Ursodeoxycholic acid is the mainstay treatment medicine for primary biliary cholangitis(PBC). About 1/3 of the patients do not respond to UDCA, which is defined as refractory PBC.
- Trial name
- NCT03668145
- Where
- China
- Volunteers
- 140 people
- Sponsor
- Xijing Hospital of Digestive Diseases
Aging
Clinical Trial to Evaluate the Potential Efficacy and Safety of Human Umbilical Cord Blood and Plasma
This study aims to carry out a safety evaluation of human cord blood and frozen plasma as treatment for pre-frailty , to assess whether the treatment can prevent and improve the aging process, and to identify useful clinical…
- Trial name
- NCT02418013
- Testing
- Fresh cord blood(experimental group A), Frozen cord blood(experimental group B), Frozen plasma(experimental group C)
- Where
- South Korea
- Volunteers
- 64 people
- Sponsor
- Bundang CHA Hospital
Oncology, Fatigue
The Effect of Self-Management Program Based on the Individual and Family Self-management Theory on Cancer Patients
The purpose of this study is to evaluate the effect of Self-Management Program based on the Individual and Family Self-management Theory on fatigue, daily living activities and well-being of cancer patients.
- Conditions
- Oncology, Fatigue, Patient
- Trial name
- NCT04822220
- Testing
- Fatigue Self-management Programme
- Where
- Turkey (Türkiye)
- Volunteers
- 94 people
- Sponsor
- Akdeniz University
Alzheimer Disease, Healthy Aging
Telerehabilitation Alzheimer's Disease Feasibility (TADF)
This is a pilot RCT with equal arms: experimental arm and (wait list) control arm. All participants will be in the early stage of Alzheimer's disease and on stable medication.
- Trial name
- TADF (NCT04732182)
- Testing
- BrightGo cognitive training, Standard of Care medication for early Alzheimer's Disease
- Where
- 2 sites in United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Bright Cloud International Corp
Vestibular Syndrome, Optokinetic Stimulation
Virtual Reality Compared to Other Forms of Optokinetic Stimulation in the Rehabilitation of Vestibular Syndromes.
Context and justification: Vertigo leads to medical consultation, interruption of daily activities or work stoppage in 80% of cases. Optokinetic stimulation is used in awareness and adaptation exercises.
- Trial name
- EquiRV (NCT03838562)
- Testing
- Vestibular rehabilitation with virtual reality, Standard optokinetic stimulator or dynamic visual surround
- Where
- France
- Volunteers
- 76 people
- Sponsor
- University Hospital, Montpellier
COVID-19, Vaccines
Immunogenicity Evaluation of Omicron Variant-based Vaccine and a Trivalent Vaccine in Adults Against COVID-19 in Chile
Phase 2 clinical trial in adults previously vaccinated against SARS-CoV-2 in Chile with an initial schedule of two doses of CoronaVac® plus two booster doses with different vaccines.
- Trial name
- CoronaVarCL (NCT05593042)
- Testing
- CoronaVac®, Omicron Vaccine, Trivalent Vaccine
- Where
- 3 sites in Chile
- Volunteers
- 551 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidad Catolica de Chile
Healthy Individuals, Shellac Nail Polish
Effect of Shellac Nail Polish Application on Pulse Oximetry Measurements in Healthy Individuals
The aim of this study was to determine the effect of shellac nail polish application on pulse oximetry measurements in healthy subjects.
- Conditions
- Healthy Individuals, Shellac Nail Polish, Oxygen Saturation, Nursing
- Trial name
- NCT06101641
- Testing
- Shellac nail polish application
- Where
- Turkey (Türkiye)
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- Tarsus University
HIV Infections
A Randomized Trial to Prevent HIV Among Gay Couples
The proposed study is a randomized controlled intervention to reduce sexual risk for HIV among HIV-negative concordant and HIV discordant gay couples.
- Trial name
- NCT03189394
- Testing
- PRIDE, ePRIDE, Men's Health
- Where
- United States
- Volunteers
- 600 people
- Sponsor
- San Francisco State University
Sedentary Behavior, Cardiometabolic Risk Factors
Breaking up Prolonged Sedentary Behavior to Improve Cardiometabolic Health
The purpose of this Phase 1 research study is to answer two questions: (1) How frequent should periods of prolonged sedentary time be interrupted? and (2) What is the appropriate duration or length of time of these breaks in…
- Conditions
- Sedentary Behavior, Cardiometabolic Risk Factors, Blood Pressure, Glucose
- Trial name
- NCT05353322
- Testing
- Sedentary Break (Walking) Condition, Sitting (Control) Condition, Controlled Diet
- Where
- United States
- Volunteers
- 324 people, healthy volunteers welcome
- Sponsor
- Columbia University
Breastfeeding Self-Efficacy Attitude to Health Postpartum Period Primiparity
Client-Centered Breastfeeding Support: Effects on Primipara Mothers in a Randomized Trial Breastfeeding Self-Efficacy, Attitudes, and Problems in Primiparous Mothers: A Randomized Controlled Trial
Study Description The goal of this randomized controlled trial is to examine the effects of a client health behavior interaction model-based breastfeeding support program on breastfeeding self-efficacy, attitudes, and problems in…
- Trial name
- NCT06446362
- Testing
- IMCHB-Based Breastfeeding Support Program, Standard Breastfeeding Education
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Pamukkale University
Ulcerative Colitis, Inflammatory Bowel Diseases
Examining the Efficacy of Fecal Microbiota Transplantation (FMT) and Dietary Fiber in Patients With Ulcerative Colitis
A double-blind, randomized, placebo-controlled clinical trial examining the efficacy and safety of Fecal Microbiota Transplantation (FMT) and high fiber supplementation in patients with active mild to moderate Ulcerative Colitis…
- Trial name
- MINDFUL (NCT03998488)
- Testing
- Fecal Microbiota Transplantation, Psyllium Husk Powder
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Weill Medical College of Cornell University
Gastroparesis Postoperative, Delayed Gastric Emptying Following Procedure
Acupuncture for Postoperative Gastric Emptying Delay
This multicenter clinical trial, conducted at Qilu Hospital of Shandong University and collaborating institutions, prospectively assesses the efficacy and safety of acupuncture for postoperative delayed gastric emptying.
- Trial name
- APOGEE (NCT07505927)
- Testing
- Acupuncture
- Where
- China
- Volunteers
- 176 people
- Sponsor
- Qilu Hospital of Shandong University
Rectal Cancer
Neoadjuvant Moderately Hypofractionated Radiotherapy Combined with Chemotherapy and Immunotherapy for High-risk LARC
This study aims to evaluate the effectiveness and safety of combining moderately hypofractionated radiotherapy with chemotherapy and anti-PD-1 antibodies as a neoadjuvant treatment for high-risk locally advanced rectal cancer.
- Trial name
- iMHRT-LARC (NCT06599827)
- Testing
- moderately hypofractionated radiotherapy, chemotherapy, immunotherapy
- Where
- China
- Volunteers
- 54 people
- Sponsor
- Shanghai Zhongshan Hospital
Acute Bronchitis, Acute Exacerbations of Chronic Bronchitis
A Multicenter, Randomized, Double-blind, Parallel Group Study to Determine the Optimal Dose of HL301 After 7 Days Oral Administration in Acute Bronchitis or Acute Exacerbations of Chronic Bronchitis Patients (HL301: Mixed Extract of Rehmannia Glutinosa, Schisandra and so on)
The purpose of this study is to determine the optimal dose of HL301 in patients with acute bronchitis or acute exacerbations of chronic bronchitis.
- Trial name
- HL301 (NCT02250027)
- Testing
- HL301 300mg capsule
- Where
- South Korea
- Volunteers
- 156 people
- Sponsor
- Hanlim Pharm. Co., Ltd.
Pain, Fear
Stress Ball Use During Cataract Surgery: Effects on Pain, Fear and Satisfaction
The aim of this study is to determine the effect of stress ball use during cataract surgery on patients' pain, fear, and satisfaction levels.
- Conditions
- Pain, Fear, Stress Ball, Nursing
- Trial name
- SBUDCS (NCT07452770)
- Testing
- Use of a stress ball during cataract surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 69 people
- Sponsor
- Bezmialem Vakif University
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