Clinical trials: Experimental Group, completed
Coronary Heart Disease (CHD)
Metoprolol and Trimetazidine for Coronary Heart Disease With Angina
This is a prospective, randomized study to evaluate the effectiveness and safety of combining metoprolol succinate with trimetazidine compared to standard therapy for patients with coronary heart disease (CHD) and angina…
- Trial name
- NCT07074834
- Testing
- Metoprolol Succinate Sustained-Release Tablets, Trimetazidine, Routine Drug Therapy
- Where
- China
- Volunteers
- 102 people
- Sponsor
- Shiyan City Renmin Hospital
Peritoneal Dialysis
Usefulness of Sterile Adhesive Dressing at the Exit-site of Peritoneal Dialysis Catheter
Infection of peritoneal dialysis fluid is a major complication in patients treated with peritoneal dialysis (PD). The aim of catheter emergence care is to reduce bacterial contamination of the peritoneum.
- Trial name
- PANCADIPE (NCT03677063)
- Testing
- No dressing
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Caen
Kidney Disease
Inspiratory Muscle Training in Patients With End-stage Renal Disease
Background: Patients with chronic kidney disease on hemodialysis may have reduced diffusion capacity, lung function and gas exchange due to mechanical and hemodynamic changes in the respiratory system, and decreased respiratory…
- Trial name
- NCT02599987
- Testing
- POWERbreathe® Classic Light
- Where
- Brazil
- Volunteers
- 24 people
- Sponsor
- Universidade Federal de Pernambuco
Medically Assisted Procreation (MAP), Oocyte Retrieval
Monocentric Randomised Controlled Trial to Assess Whether Virtual Reality Reduces the Use of Hypnotic Agents During IVF/ICSI Oocyte Retrieval
Over the last few years, audiovisual distraction devices using animation, films and 3D immersion have been developed, with the aim to provide patients with a relaxing experience that disconnects them from the operating…
- Trial name
- REVAHPOVO (NCT07190729)
- Testing
- Propofol sedation + Audiovisual distraction, Propofol sedation
- Where
- France
- Volunteers
- 52 people
- Sponsor
- Groupe Hospitalier Diaconesses Croix Saint-Simon
Parkinson Disease
Forensic Handwriting Analysis in People with Parkinson's Disease - Pilot Study
Graphoscopic analysis of handwriting is influenced by various internal and external factors, and individuals with degenerative diseases like Parkinson's face challenges due to limitations in motor abilities, impacting…
- Trial name
- NCT06693401
- Testing
- Intervention group: PD rehabilitation complemented with Occupational Therapy programme, Control Group: conventional physiotherapy programme
- Where
- Portugal
- Volunteers
- 10 people
- Sponsor
- Egas Moniz - Cooperativa de Ensino Superior, CRL
Prostate Cancer
Phase II Study of DCVAC/PCa After Primary Radiotherapy for Patients With High Risk Localized Prostate Cancer
The purpose of this study is to determine whether DCVAC/PCa added after radical primary prostatectomy can improve PSA progression times within 5 years for patients with high risk localized Prostate Cancer.
- Trial name
- NCT02107430
- Testing
- Dendritic Cells DCVAC/PCa, Standard radiotherapy
- Where
- 6 sites in Czechia
- Volunteers
- 62 people
- Sponsor
- SOTIO a.s.
Neck Pain, Chronic Pain
Using Mobile Application for Rehabilitation in Patients With Chronic Neck Pain
The aim of this study is to reduce pain, increase range of motion, increase the endurance of deep cervical flexors muscles, and increase quality of life with mobile application in the treatment of patients with chronic neck pain.
- Trial name
- NCT05284630
- Testing
- Exercise follow up with mobile application, Home-Based Exercise Program followed by paper booklet, Electrotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people
- Sponsor
- Saglik Bilimleri Universitesi
Cardiovascular Diseases
Second eFramngham Heart Study
In the electronic Framingham Heart Study (eFHS), the investigators developed and deployed a mobile app to collect cardiovascular risk factors and event data and test them against cardiovascular data collected in the Framingham…
- Trial name
- eFHS-2 (NCT04752657)
- Testing
- Delayed administration of survey modules, Regular administration of survey modules
- Where
- United States
- Volunteers
- 492 people
- Sponsor
- Boston University
Stroke
Effect of Speed-dependent Treadmill Training in Patients With Subacute Stroke
This study aimed to explore whether speed-dependent treadmill training is more effective at improving walking and balance performance than speed-stable treadmill training in patients with subacute stroke.
- Trial name
- NCT01328301
- Testing
- Experimental, Speed-stable treadmill training
- Where
- China
- Volunteers
- 30 people
- Sponsor
- The Hong Kong Polytechnic University
Total Knee Arthroplasty
Impact of Prehabilitation in Total Knee Replacement
A study comparing the benefits of pre-habilitation exercise to standard care prior to total knee arthroplasy
- Trial name
- NCT01844934
- Testing
- Prehabilitation
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- Allina Health System
Mood Disorders
Efficacy and Safety of TMS and Deep TMS Treatment for Psychiatric and Neurological Disorders
The goal of this study is to examine the efficacy and safety of transcranial magnetic stimulation (TMS) and deep TMS (dTMS) for treatment of different psychiatric and neurological disorders.
- Trial name
- NCT02917499
- Testing
- TMS
- Where
- Croatia
- Volunteers
- 228 people
- Sponsor
- Sveti Ivan Psychiatric Hospital
Atrial Fibrillation
Characterisation of Fractionated Electrograms Critical for Maintenance of Atrial Fibrillation (AF)
The purpose of this study is to characterise which fractionated electrogram morphologies are important to target in the catheter ablation of atrial fibrillation.
- Trial name
- CAFE AF (NCT00894400)
- Testing
- catheter ablation
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- Barts & The London NHS Trust
Infertility
Evaluation of SiD's System for Improving Assisted Reproduction Treatments
According to the WHO, infertility affects 15% of reproductive age couples worldwide. Among the assisted reproductive technologies available for patients with infertility, intracytoplasmic sperm injection (ICSI) has become one of…
- Trial name
- NCT05611164
- Testing
- Software assisted selection of individual spermatozoa for intracytoplasmic sperm injection
- Where
- 2 sites in Mexico
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- IVF 2.0 Limited
Aphasia, Apraxia of Speech
Investigating the Effects of Rhythm and Entrainment on Fluency in People With Aphasia
Speaking in unison with another person is included as a part of many treatment approaches for aphasia. It is not well understood why and how this technique works.
- Trial name
- NCT05248295
- Testing
- Unison speech (vs. solo), Metrical timing (vs. conversational)
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- MGH Institute of Health Professions
Peripheral Nerve Injury at Forearm Level (Diagnosis)
Effects of Motor Learning After Upper Limb Peripheral Nerve Injury
The outcome of peripheral nerve injury is related to age, level of injury, the injured nerve, the severity of injury, and the timing and the type of surgery interventions.
- Trial name
- NCT04087577
- Testing
- conventional physical therapy, mirror therapy
- Where
- 2 sites in Taiwan
- Volunteers
- 8 people
- Sponsor
- Chang Gung Memorial Hospital
Seasonal Allergic Rhinitis
Clinical Equivalence Study of Mometasone Nasal Spray, 50 Mcg/Actuation
The objective of this study is to evaluate the clinical equivalence of the test formulation of mometasone furoate anhydrous 50 mcg/actuation nasal spray (manufactured by Teva Pharmaceutical Industries, Ltd.
- Trial name
- NCT01523236
- Testing
- Mometasone furoate, Nasonex®
- Volunteers
- 800 people
- Sponsor
- Teva Pharmaceuticals USA
X-linked Adrenoleukodystrophy
SMART-ALD - A New Lifestyle Intervention to Improve Quality of Life in Women With X-linked Adrenoleukodystrophy (X-ALD)
X-linked Adrenoleukodystrophy (X-ALD) is one of the most frequent inborn error of metabolism caused by mutations in the ABCD1 gene, which codes for the transporter of saturated very long-chain fatty acids (VLCFA) for peroxisomal…
- Trial name
- NCT04687007
- Testing
- SMART-ALD, Waiting list
- Where
- 2 sites in Germany
- Volunteers
- 68 people
- Sponsor
- Leipzig University Medical Center
Mental Well-being, Mental Health Literacy
Evaluation of Chatbot for Mental Well-being
The present study consists of two two-armed randomized controlled trials between experimental and waitlist control groups. It aims to evaluate the effectiveness of conversational chatbot in improving mental health literacy…
- Trial name
- NCT05694507
- Testing
- Mental Well-being Chatbot
- Where
- Hong Kong
- Volunteers
- 293 people
- Sponsor
- Chinese University of Hong Kong
Critical Illness, Social Isolation
Reducing Isolation and Feeling of Loneliness During Critical Illness
The trial is a pilot-randomized trial testing feasibility and limited-efficacy of delivering social engagement using technologic strategies to reduce periods of social isolation.
- Conditions
- Critical Illness, Social Isolation, Anxiety, Depression
- Trial name
- SOCIAL (NCT05537311)
- Testing
- Social Engagement
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Kirby Mayer
Non-small Cell Lung Cancer Stage II, Non-small Cell Lung Cancer Stage I
SBRT With Immunotherapy in Early Stage Non-small Cell Lung Cancer: Tolerability and Lung Effects
This is a single arm, multi-centre, phase II open label study of nivolumab with stereotactic body radiotherapy (SBRT) for early stage non-small cell lung cancer.
- Trial name
- STILE (NCT03383302)
- Testing
- Stereotactic body radiotherapy, Nivolumab
- Where
- United Kingdom
- Volunteers
- 36 people
- Sponsor
- Royal Marsden NHS Foundation Trust
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