Clinical trials: Experimental Group
Cardiovascular Diseases, Heart Diseases
Examining Psychosocial Mediators of Exercise Behavior
The purpose of this study is to examine psychosocial mediators of exercise behavior.
- Trial name
- NCT00142688
- Testing
- Physical activity, Wellness
- Where
- United States
- Volunteers
- 448 people, healthy volunteers welcome
- Sponsor
- HealthPartners Institute
ASD
Evaluate the Efficacy and Safety of DHA in the Adjuvant Treatment of Children With ASD.
In the etiopathogenesis of autistic spectrum disorder (ASD) several hypotheses have been described that include inflammation, metabolic alterations, activation of oxidative stress, changes in the intestinal microbiota and in the…
- Trial name
- NCT03620097
- Testing
- EuPoly-3 DHA Infant
- Volunteers
- 60 people
- Sponsor
- Maimónides Biomedical Research Institute of Córdoba
AML (Acute Myelogenous Leukemia), Acute Lymphoid Leukemia (ALL)
A Platform Protocol to Investigate Post-Transplant Cyclophosphamide-Based Graft-Versus-Host Disease Prophylaxis in Patients With Hematologic Malignancies Undergoing Mismatched Unrelated Donor Peripheral Blood Stem Cell Transplantation
The purpose of this clinical trial is to compare drug combinations to learn which drugs work best to prevent graft-versus-host-disease (GVHD) in people who have received a stem cell transplant.
- Conditions
- AML (Acute Myelogenous Leukemia), Acute Lymphoid Leukemia (ALL), Acute Leukemia (Category), MDS (Myelodysplastic Syndrome)
- Trial name
- ACCELERATE (NCT06859424)
- Testing
- Conditioning Regimen A, Conditioning Regimen B, Conditioning Regimen C
- Where
- 13 sites in United States
- Volunteers
- 358 people
- Sponsor
- Center for International Blood and Marrow Transplant Research
Healthy
INVSENSOR00032 and INVSENSOR00033 Respiration Rate Clinical Performance Study
This study compares the performance of respiration rate from pleth measured prospectively with either INVSENSOR00032 and/or INVSENSOR00033 devices against the respiration rate derived from the manual scoring of the capnography…
- Trial name
- NCT03897179
- Testing
- INVSENSOR00032 and INVSENSOR00033
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Masimo Corporation
Colorectal Adenocarcinoma Metastatic in the Liver
Retlirafusp Alfa Plus Targeted Therapy and Chemotherapy for Unresectable Colorectal Liver-Limited Metastases
This is a single-center, open-label, exploratory phase II trial to evaluate efficacy and safety of Retlirafusp alfa (PD-L1/TGF-βRII bispecific fusion protein) combined with standard first-line targeted-chemotherapy as conversion…
- Trial name
- NCT07815288
- Testing
- Retlirafusp alfa Combined with Targeted Therapy and Chemotherapy
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Peking University Cancer Hospital & Institute
Hearing Loss
Clinical Study of Released Unitron RIC and BTE Hearing Aid Models
The present study will confirm the clinical benefit of 2 different released hearing aid models for speech understanding (in noise).
- Trial name
- NCT05197803
- Testing
- Hearing aid
- Where
- Canada
- Volunteers
- 25 people
- Sponsor
- Sonova AG
Healthy
Influence of an Inspiratory Muscle Fatigue Protocol on Older Adults on Respiratory Muscle Strength and Heart Rate Variability
Respiratory muscle training represents an effective method increasingly utilized in both sports and healthcare domains, employing various devices, among which threshold devices are prominent.
- Trial name
- NCT06269042
- Testing
- Inspiratory muscle training
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Sierra Varona SL
Entrustable Professional Activities, Mini-clinical Evaluation Exercise
Exploring the Relationship Between Mini-Clinical Evaluation Exercise (Mini-CEX) and Entrustable Professional Activities (EPAs) in Occupational Therapy Clinical Interns' Independent Competence
The goal of this observational cross-sectional study is to evaluate whether the combined use of Mini-Clinical Evaluation Exercise (Mini-CEX) and Entrustable Professional Activities (EPAs) can assess the independent clinical…
- Conditions
- Entrustable Professional Activities, Mini-clinical Evaluation Exercise, Physical Occupational Therapy, Occupational Therapy Education
- Trial name
- NCT07107542
- Testing
- Mini-Clinical Evaluation Exercise (Mini-CEX) and Entrustable Professional Activities (EPAs) Assessment
- Where
- Taiwan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Far Eastern Memorial Hospital
Overlap Syndrome, Nocturnal Hypoventilation
Continuous Positive Pressure Versus Bi-level in Overlap Syndrome
Continuous positive airway pressure (CPAP) became the established treatment for overlap syndrome (OS). It has been showed that the survival benefits of CPAP favored hypercapnic patients.
- Trial name
- NCT03766542
- Testing
- Bi-level positive airway pressure with ventilatory support, continuous positive airway pressure without ventilatory support
- Volunteers
- 70 people
- Sponsor
- Hospital Sao Joao
Comfort, Pain
The Effect of Nursing Care Based on Kolcaba Comfort Theory in the Delivery Room
Newborns may experience pain, stress, and physiological changes during and after birth. Appropriate nursing care during this period can reduce negative effects by increasing the baby's comfort.
- Trial name
- kolcaba Comfor (NCT07148570)
- Testing
- Nursing Care Based on Kolcaba's Comfort Theory
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Chronic Stroke
Universal Exercise Unit Therapy With Sling Exercise Therapy on Lower Limb Kinematics in Chronic Stroke Patients
Stroke occurred when blood supply to brain or a part of brain is disturbed due to clot (ischaemic stroke) or due rupture of small vessels (hemorrhagic stroke) in brain and causes bleeding in brain cells.
- Trial name
- NCT05033873
- Testing
- Universal Exercise Unit Therapy (UEU), Sling Exercise Therapt (SET), Routine Physical Therapy / Control Group
- Where
- Pakistan
- Volunteers
- 90 people
- Sponsor
- Riphah International University
Anxiety State, Esketamine
Effect of Esketamine on Anxiety State in Patients Undergoing Abdominal Tumor Surgery
To evaluate whether esketamine can relieve anxiety in patients undergoing abdominal tumor surgery.
- Trial name
- NCT06530706
- Testing
- Esketamine, normal saline
- Where
- China
- Volunteers
- 185 people
- Sponsor
- Zhejiang Cancer Hospital
Low-Density-Lipoprotein-Type [LDL] Hyperlipoproteinemia
Effect of Early Initiation of Evolocumab on Lipid Profiles Changes in Patients With ACS Undergoing PCI
Investigators aimed to evaluate efficacy and safety of early Initiation of evolocumab and combination lipid-lowering agent (statin + Ezetimibe) on lipid profiles changes in patients with ACS undergoing PCI
- Trial name
- C-STAR (NCT05661552)
- Testing
- Evolocumab 140 MG/ML, Rosuvastatin 5mg, Ezetimibe 10mg
- Where
- South Korea
- Volunteers
- 108 people
- Sponsor
- Yonsei University
Depression, Anxiety
Feasibility and Acceptability Trial of a Video Based CBT Guided Self Help Intervention for People With Low Literacy
This study aimed to assess the feasibility, acceptability, and preliminary efficacy of a video-based CBT guided self-help intervention 'Khushi or Khatoon' to treat anxiety and depression.
- Trial name
- VCBT (NCT05986747)
- Testing
- Video-based CBT guided self-help Interventions
- Where
- Pakistan
- Volunteers
- 14 people
- Sponsor
- Pakistan Association of Cognitive Therapists
Procrastination, Educational Intervention
Impact of Slavin's Effective Teaching Model on Procrastination in Nursing Students: a Quasi-Experimental Study
The purpose of this clinical trial is to determine if a time management training program can effectively reduce procrastination behavior among intern nursing students.
- Conditions
- Procrastination, Educational Intervention, Time Management
- Trial name
- NCT06675838
- Testing
- Time Management and Procrastination Behavior Management Training
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Beykent
Evaluation of SpO2 Performance
Feasibility and Performance Evaluation for INVSENSOR00024
This is a prospective, non-randomized, single arm study design to evaluate SpO2 performance of the RD SET Neo investigational pulse oximeter sensors in the neonatal population using convenience sampling in a clinical environment.
- Trial name
- NCT03570255
- Testing
- RD SET Neo SpO2
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Masimo Corporation
Surgical Complication, Pain, Postoperative
Anti-inflammatory Effect of Platelet-Rıch Fıbrın
This study evaluated the anti-inflammatory effect of platelet-rich fibrin (PRF) applied to the extraction socket after impacted mandibular third molar surgery with subjective and objective parameters.
- Conditions
- Surgical Complication, Pain, Postoperative, Edema Face
- Trial name
- NCT05336578
- Testing
- Platelet rich fibrin application
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Nilay Er
Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Reconstruction
Effect of Intraoperative Live Video Viewing on Kinesiophobia After ACL Reconstruction
The purpose of this randomized controlled trial is to investigate whether intraoperative live arthroscopic video viewing improves postoperative psychological and functional outcomes in patients undergoing primary anterior…
- Conditions
- Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Reconstruction, Kinesiophobia, Anxiety
- Trial name
- VIDEO-ACLR (NCT07540715)
- Testing
- Intraoperative Live Video Viewing, Standard ACL Reconstruction
- Where
- Turkey (Türkiye)
- Volunteers
- 65 people
- Sponsor
- Konya City Hospital
Pediatric Kidney Transplant Recipients
Dose-adjustment of Enoxaparin by a Bayesian Pharmacological Approach in Pediatric Kidney Transplant Recipients (OPTI-TREX)
Allograft vascular thrombosis is a devastating complication in kidney transplantation in adults and older children. Though uncommon, it is often irreversible and represents the main cause of graft loss within after kidney…
- Trial name
- OPTI-TREX (NCT05672550)
- Testing
- Bayesian based dose adjustment of enoxaparin, Usual dose adjustment of enoxaparin
- Where
- 10 sites in France
- Volunteers
- 50 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Nursing Caries
The Effectiveness of Modified Childbirth Education Program
A randomized control trial to test the effectiveness of childbirth education programs on maternal anxiety, maternal-fetal attachment, childbirth self-efficacy, and marital satisfaction based on Roy Adaptation Model.
- Trial name
- NCT04759118
- Testing
- modified childbirth education program
- Where
- Indonesia
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Endang Koni Suryaningsih
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