Clinical trials: Experimental Group, completed
Frailty, Morbidity, Multiple
Low-volume Cycling Training in Older People With Multimorbidity
INTRODUCTION: Physical exercise, when practiced regularly and in adequate doses, is a proven nonpharmacological measure that helps to prevent and reverse noncommunicable diseases, as well as reduce mortality rates from any cause.
- Trial name
- NCT04842396
- Testing
- Experimental:Motorized cycle ergometer
- Where
- Spain
- Volunteers
- 24 people
- Sponsor
- Universidade da Coruña
Varicose Veins, Vascular Diseases
New Compression Hosiery Versus Standard Class II Compression Stockings After Endothermal Ablation
A prospective comparative randomized multicentre non-inferiority trial. The purpose of this study is to compares of a short compression hosiery (stocking without a foot, compression class 2) with standard compression class 2…
- Trial name
- COSMOS (NCT03477227)
- Testing
- Short stocking, Usual stocking
- Where
- 3 sites in Russia
- Volunteers
- 187 people
- Sponsor
- Pirogov Russian National Research Medical University
Prevention of HIV Infection, HIV Antibodies
Safety and Pharmacokinetics of a Human Monoclonal Antibody, VRC-HIVMAB080-00-AB (VRC01LS), With Broad HIV-1 Neutralizing Activity, Administered Intravenously or Subcutaneously to Healthy Adults
Background: Antibodies help the body fight infection. VRC01LS is an antibody directed against HIV virus. HIV attacks the immune system. In animals, VRC01LS inactivated many types of HIV viruses.
- Conditions
- Prevention of HIV Infection, HIV Antibodies, Monoclonal Antibody, Human, Neutralizing Antibody
- Trial name
- NCT02599896
- Testing
- VRC-HIVMAB080-00-AB (VRC01LS), VRC-HIVMAB060-00-AB (VRC01)
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Vitiligo
Combination of Methotrexate and Phototherapy Versus Phototherapy in Adults With Progressive Vitiligo
This is a phase 2, randomized, double blind, multicenter study evaluating the efficacy and safety of the combination of methotrexate plus UVB TL01 in vitiligo.
- Trial name
- METVI (NCT04237103)
- Testing
- Methotrexate
- Where
- 4 sites in France
- Volunteers
- 32 people
- Sponsor
- University Hospital, Bordeaux
Herpes Zoster
A Study to Evaluate the Safety and Immunogenicity of ChAdOx1-VZV in Healthy Adults Aged 50-65 Years
This is a randomized, observer blind and controlled study. Participants in low-dose and high-dose IM group will be randomized in a ratio of 2:1 to receive either the investigational product or the control.
- Trial name
- NCT05991427
- Testing
- Recombinant Zoster Vaccine (Adenovirus Vector) (ChAdOx1-VZV), Zoster Vaccine Recombinant, Adjuvanted (Shingrix), ChAdOx1-VZV
- Where
- Canada
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- CanSino Biologics Inc.
Head and Neck Cancer
Nurse-led Follow-up Care for Head and Neck Cancer Patients
The purpose of this study is to conduct an early evaluation of a nurse-led follow up intervention added to the usual medically oriented follow up care.
- Trial name
- NCT01167179
- Testing
- nurse-led consultation
- Where
- Netherlands
- Volunteers
- 160 people
- Sponsor
- Radboud University Medical Center
Resistance Training, Recovery
Blood Flow Restriction and Recovery in Soccer Players
The objective is to evaluate the effects of blood flow restriction training on the post-competition recovery of professional and semi-professional soccer players.
- Trial name
- NCT05097027
- Testing
- Blood flow restriction recovery, Active recovery
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of the Balearic Islands
COVID-19
Evaluation of Safety & Efficacy of MIR 19 ® Inhalation Solution in Patients With Moderate COVID-19
This is Phase 2 multi-center controlled randomized study to assess the efficacy and safety of MIR 19® via 14 days of treatment of participants with symptomatic moderate COVID-19.
- Trial name
- NCT05184127
- Testing
- MIR 19 ®, Standard COVID-19 therapy
- Where
- Russia
- Volunteers
- 156 people
- Sponsor
- National Research Center - Institute of Immunology Federal Medical-Biological Agency of Russia
Volleyball Players
Effects of Omega-3 Supplementation on Exercise Performance, Body Composition, and Appetite Status in Female Athletes
Volleyball is a sport that requires high performance and aims to increase endurance. The intense training and competition tempo of athletes directs them to special nutritional needs.
- Trial name
- RCT (NCT07054762)
- Testing
- omega-3 supplements in female athletes
- Where
- Turkey (Türkiye)
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Betul Uner
Hepatitis C Virus Infection, Response to Therapy of, Human Immunodeficiency Virus
CHAMPS Study: Chronic HepAtitis C Management to ImProve OutcomeS
This study is being done to compare three strategies to deliver HCV treatment with ledipasvir/sofosbuvir which is an approved therapy which is administered as one tablet by mouth daily for 12 weeks.
- Trial name
- CHAMPS (NCT02402218)
- Testing
- Usual care plus peer-mentors, Usual care plus incentives, Usual Care
- Where
- United States
- Volunteers
- 144 people
- Sponsor
- Johns Hopkins University
Sleep Deprivation, Postoperative Pain
The Effect of Night Eye Mask on Post-operative Pain in Cardiac Surgery Patients
Environmental factors such as noise and light have been cited as important causes of sleep deprivation in Intensive care unit (ICU) patients.
- Trial name
- NCT03213860
- Testing
- Flight Eye-masks; Dreaming, Zhuji City, Zhejiang, China
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Assiut University
Healthy Volunteers
Effect of Interest-Based Physical Training on Exercise Adherence
This study aims to examine whether a physical training program designed based on individual interests can improve exercise adherence and physical fitness among college students, and to explore whether positive affective…
- Trial name
- NCT07635927
- Testing
- Interest-Based Physical Training;, Regular Physical Training
- Where
- China
- Volunteers
- 560 people, healthy volunteers welcome
- Sponsor
- Capital University of Physical Education and Sports, China
Gastric Cancer
Gastric Partitioning Procedure for the Treatment of Unresectable and Obstructive Distal Gastric Cancer
The incidence of unresectable and obstructive gastric cancer patients ranges in the literature from 5 to 30 % . In such cases, gastro-entero anastomosis is traditionally performed and can improve the quality of life by relieving…
- Trial name
- NCT02064803
- Testing
- Gastro-entero anastomosis only, Gastric partitioning Plus Gastro-entero anastomosis
- Where
- Brazil
- Volunteers
- 52 people
- Sponsor
- Instituto do Cancer do Estado de São Paulo
Edema Secondary, Edema Leg
A Dose-finding Study of JMKX003142 in Treatment of Renal Edema
To evaluate the safety,efficacy, and pharmacokinetic characteristics of JMKX003142 administered randomly, double-blind, placebo-controlled study in Chinese renal edema patients with inadequate response to conventional diuretic…
- Trial name
- NCT06670534
- Testing
- JMKX003142 tablets
- Where
- 2 sites in China
- Volunteers
- 133 people
- Sponsor
- Jemincare
Diabetes Mellitus, Diabetic Foot Ulcer
Relaxation Intervention in Patients With Diabetic Foot Ulcer
Diabetic foot ulcers (DFU) are one of the most serious complications of diabetes and can lead to amputations in 85% of cases, resulting in physical, psychological, family, social and economic consequences.
- Trial name
- NCT04652999
- Testing
- Muscle Relaxation with Guided Imagery, Neutral Guided Imagery
- Where
- 2 sites in Portugal
- Volunteers
- 54 people
- Sponsor
- University of Minho
Chronic Low Back Pain
The Effects of Fish Oil on Patients With Chronic Nonspecific Low Back Pain
Objectives: To investigate the efficacy of omega-3 polyunsaturated fatty acids (PUFA) on patients with chronic nonspecific low back pain (NLBP).
- Trial name
- NCT02774109
- Testing
- Fish oil, Hotpacking, Transcutaneous electrical nerve stimulation (TENS)
- Where
- Taiwan
- Volunteers
- 29 people
- Sponsor
- Chang Gung Memorial Hospital
Arteriovenous Fistula, Isometric Exercise
The Effect of Intelligent Exercise on Vascular Function, Grip Strength and Adherence in Patients With AVF After Surgery
Isometric exercise can effectively promote the vascular function of arteriovenous fistula and increase hand grip strength, but patients needs to perform isometric exercises patiently.
- Trial name
- NCT05686200
- Testing
- Forearm isometric exercise intervention program
- Where
- Taiwan
- Volunteers
- 52 people
- Sponsor
- National Taipei University of Nursing and Health Sciences
BK Virus Nephropathy After Kidney Transplantation
Multicenter Randomized Two-arms Study Evaluating the BK Viral Clearance in Kidney Transplant Recipients With BK Viremia.
BK virus nephropathy (BKVN), a consequence of the strong immunosuppressive therapy given after kidney transplantation, represents a growing problem in the kidney transplant (KT) setting.
- Trial name
- BK EVER (NCT03216967)
- Testing
- everolimus
- Where
- 15 sites in France
- Volunteers
- 130 people
- Sponsor
- University Hospital, Strasbourg, France
Radiculopathy Lumbar, Disk Herniated Lumbar
Position-Induced Opening of the Intervertebral Foramen is Efficient to Treat an Acute Lumbosacral Radiculopathy Caused by Disc Herniation
Efficiency of the conservative mechanical lumbosacral nerve root decompression, as an adjunct to pharmacological treatment, in the case of acute lumbosacral radiculopathy.
- Conditions
- Radiculopathy Lumbar, Disk Herniated Lumbar, Low Back Pain
- Trial name
- NCT04276519
- Testing
- Physiotherapeutic, non-invasive position-induced opening of the intervertebral foramen
- Volunteers
- 20 people
- Sponsor
- General Hospital Sveti Duh
Gynecology, Gynecology/Obstetrics Conditions
Gynaecological Examination Gown and Patient Satisfaction
The attitude of the health personnel before, during and after the examination and the positive examination experience of the person have a significant impact on ensuring the continuity of the subsequent examination and increasing…
- Trial name
- NCT06324019
- Testing
- putting on an examination gown
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- ayşegül muslu
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