Clinical trials: Experimental Group
Gastric or Gastroesophageal Junction Adenocarcinoma
Efficacy and Safety of Intraoperative Radiotherapy Combined With Serplulimab Plus Chemotherapy Versus Serplulimab Plus Chemotherapy as Neoadjuvant Therapy for Gastric or Gastroesophageal Junction Adenocarcinoma
This study evaluates the clinical efficacy and safety benefits of neoadjuvant intraoperative radiotherapy combined with immunotherapy and chemotherapy by comparing intraoperative radiotherapy plus serplulimab plus chemotherapy…
- Trial name
- NICT-IORT (NCT07870798)
- Testing
- Serplulimab, Intraoperative exploration plus intraoperative radiotherapy, Intraoperative exploration without intraoperative radiotherapy
- Volunteers
- 68 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Malaria
Trial to Evaluate CIS43LS in Healthy Adults
Background: People get malaria when they are bitten by an infected mosquito. Malaria can be serious and sometimes deadly. Although there are medicines to treat malaria, there is no vaccine that fully prevents infection.
- Trial name
- NCT04206332
- Testing
- VRC-MALMAB0100-00-AB, Plasmodium falciparum (P. falciparum) sporozoite challenge
- Where
- 2 sites in United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Covid19
Prophylaxis for COVID-19: Ivermectin in Close Contacts of COVID-19 Cases (IVERNEX-TUC)
Randomized controlled clinical trial on using oral ivermectin in COVID-19 prophylaxis supplying the drug to close contacts of confirmed cases.
- Trial name
- IVERNEX-TUC (NCT04894721)
- Testing
- Ivermectin
- Where
- Argentina
- Volunteers
- 172 people, healthy volunteers welcome
- Sponsor
- Ministry of Public Health, Argentina
Ankle Injuries
Does Performing a Composite Test 3 Months Post-operatively Reduce the Risk of Failure to Return to Sport After Lateral Ankle Ligamentoplasty?
Ankle sprain is one of the most common pathologies in the general population (between 2.1 and 3.2 per 1000 patients per year). Nearly 40% of patients will develop chronic instability in the year following the sprain.
- Trial name
- NCT06395714
- Testing
- Personnalized physiotherapy, Usual physiotherapy
- Where
- France
- Volunteers
- 116 people
- Sponsor
- Clinique du Sport, Bordeaux Mérignac
Cerebral Palsy
Study of the Effect of Compassion-Based Education Program Applied to Mothers of Children Diagnosed With Cerebral Palsy
Purpose of the study; The aim of this study is to examine the effect of a compassion-based education program applied to mothers of children with cerebral palsy on compassion fatigue, depression, and psychological resilience.
- Trial name
- NCT06245733
- Testing
- Compassion-Based Education Program Adapted for Adults
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Hasan Kalyoncu University
Rabies (Healthy Volunteers)
A Phase II Trial of a Recombinant Human Anti-Rabies Virus Monoclonal Antibody
A Phase II, Single-Center, Randomized, Blinded, Controlled Clinical Trial to Evaluate the Safety, Tolerability, and Pharmacodynamics of a Recombinant Human Anti-Rabies Virus Monoclonal Antibody Injection in Healthy Subjects
- Trial name
- NCT07445815
- Testing
- Recombinant Human Rabies Virus Monoclonal Antibody Injection, Human Rabies Immunoglobulin (HRIG), Rabies Vaccine
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Lanzhou Institute of Biological Products Co., Ltd
Digital Care-plan, Long-term Care
The Effectiveness of Digital Care-plan for Improving Long-term Care 2.0 Service Activation Proportion
Digital tools can potentially improve the public's reception to and understanding of long-term care information, which will be significantly helpful for long-term care workers and effectively increase the coverage provided by…
- Conditions
- Digital Care-plan, Long-term Care, Activation Proportion, Case Management, APP(Application)
- Trial name
- NCT05441735
- Testing
- APP
- Where
- Taiwan
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- National Taipei University of Nursing and Health Sciences
Nursing Care
The Effect of Nurse Training on the Improvement of Subcutaneous Heparin Applications
One of the most important duties and responsibilities of nurses is drug administration. During drug administration, the nurse uses appropriate administration techniques and ensures patient safety by knowing the drugs and their…
- Trial name
- NCT05469035
- Testing
- Mobile-based video, Face-to-face
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Istanbul Saglik Bilimleri University
Subarachnoid Hemorrhage, Aneurysmal, Brain Ischemia
TicAgreLor Versus Placebo to Prevent Cerebral ISCHemia in anEuRysmal Low Grade SAH A Double Blinded Randomised Controlled Study
Among aneurysmal subarachnoid hemorrhage (aSAH) survivors, ischemic injuries such as peri procedural thromboembolic events (TEE) and delayed cerebral ischemia (DCI) represent the most important disabling complications.
- Conditions
- Subarachnoid Hemorrhage, Aneurysmal, Brain Ischemia, Endovascular Procedure
- Trial name
- TALISCHER-SAH (NCT07821008)
- Testing
- Experimental group: ticagrelor
- Where
- 7 sites in France
- Volunteers
- 274 people
- Sponsor
- University Hospital, Toulouse
Hypersensitivity Dentin
Potassium Nitrate Gel and Diode Laser for Dentinal Hypersensitivity
The goal of this randomized clinical trial is to evaluate whether combining a potassium nitrate gel with diode laser therapy is more effective in treating dentinal hypersensitivity compared to using the gel alone.
- Trial name
- NCT06746558
- Testing
- Potassium Nitrate Gel and Diode Laser Therapy, Potassium Nitrate Gel Alone
- Where
- Italy
- Volunteers
- 12 people
- Sponsor
- University of Modena and Reggio Emilia
Healthy Participants
A Single- and Multiple- Ascending Dose Study to Evaluate the Safety, Tolerability and Pharmacokinetics of SYH2059 Powder for Inhalation
Randomized, double-blind and placebo-controlled study to evaluate the safety, tolerability, and pharmacokinetic characteristics of SYH2059 powder for inhalation after single and multiple doses in healthy subjects.
- Trial name
- NCT07510958
- Testing
- SYH2059
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- InnovStone Therapeutics Limited
Insomnia Disorder, Diabetes
Auricular Acupuncture Therapy Administered by Village Doctors Improves Sleep Quality in Elderly Patients With Comorbid Diabetes Mellitus and Hypertension
This study aims to apply traditional auricular press-needle acupuncture to treat sleep disturbances in elderly patients (aged ≥65 years) with comorbid diabetes mellitus and hypertension in rural areas of China.
- Conditions
- Insomnia Disorder, Diabetes, Hypertension
- Trial name
- NCT07554235
- Testing
- Auricular Acupuncture Therapy
- Where
- China
- Volunteers
- 320 people
- Sponsor
- Jiangsu Taizhou People's Hospital
Sports Injury, Body Composition
Injury Occurrence in Hip-hop Dance
The study will investigate the effect of structural training program and body composition on injury occurrence in hip-hop dance.
- Trial name
- NCT03432130
- Testing
- Structural training program
- Where
- Slovenia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Ljubljana
Pyelonephritis Acute
3-day IV Antibiotic Treatment Versus 3-day IV Followed by 7-day Oral Antibiotic Treatment for AP in Children
Antibiotic therapies currently recommended for the treatment of acute pyelonephritis (AP) in children, whether fully by the oral route or initially intravenous (IV, 3 days) followed by the oral route, have a duration of 7 to 14…
- Trial name
- PYELOCOURT (NCT05544565)
- Testing
- IV Antibacterial Agents, Orally antibacterial agents, Fecal/Rectal Swab
- Where
- 15 sites in France
- Volunteers
- 480 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Dream Disorder, Thrombotic Infarction
Biological Function of Dreaming in Dreaming and Non-Dreaming Patients With PCA Infarction
This study is a quasi-experimental between-group design. Using a prospective two-arm controlled exploratory study, data will be collected on an initial assessment of the effects of a specific neurological sample after thrombotic…
- Conditions
- Dream Disorder, Thrombotic Infarction, PCA Infarct
- Trial name
- BFD (NCT04749992)
- Testing
- Polysomnographic examination in sleep laboratory (PSG measurement)
- Where
- 2 sites in Germany
- Volunteers
- 142 people
- Sponsor
- International Psychoanalytic University Berlin
Sedentary Lifestyle
Influence of Pilates-based Exercises on Postural Balance
The study of the behavior of the mechanisms of body balance with a workout based on the Pilates method can facilitate the development of more accurate rehabilitation approaches.
- Trial name
- NCT02845544
- Testing
- Pilates-based exercises
- Where
- Brazil
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Pernambuco
Neurosurgical Surgery, Sedo-analgesia
The Effect of the Sedo-Analgesia Protocol Applied to Intensive Care Unit Patients on Patient Outcomes
Neurosurgical interventions are a leading cause of death and disability in adults, and managing intracranial hypertension in the acute phase is a critical treatment process to prevent secondary brain injury .
- Conditions
- Neurosurgical Surgery, Sedo-analgesia, İntensive Care, Nursing Care
- Trial name
- Sedo Analgesia (NCT07148544)
- Testing
- Sedo analgesia protocol, control group
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Cukurova University
Dental Caries Prevention
Silver Nanoparticle vs Chlorhexidine Mouthwashes for Reducing Streptococcus Mutans and Improving Salivary pH in Children
Dental caries remains one of the most common chronic diseases in children, with Streptococcus mutans playing a major role in its development.
- Trial name
- SMILE (NCT07728409)
- Testing
- Silver nanoparticle mouthwash (10 ppm), Chlorhexidine mouthwash (0.2%)
- Where
- Egypt
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Assiut University
Obesity, Type 2 Diabetes
Effects of Oral Sodium Butyrate Supplementation on Body Weight Reduction in Overweight/Obese Individuals With and Without Type 2 Diabetes
The goal of this clinical trial (randomized controlled trial with parallel group design) is to evaluate the effects of oral sodium butyrate supplementation for 12 weeks, compared with placebo, in addition to a moderately…
- Trial name
- ButRed (NCT07252609)
- Testing
- Sodium Butyrate (NaBut)
- Where
- Italy
- Volunteers
- 46 people
- Sponsor
- Federico II University
Fear of Childbirth, Haptonomy
The Effect of Mindfulness-Based Intervention and Haptonomy Application on Birth Self-Efficacy, Prenatal Attachment and Anxiety Levels of Pregnant Women With Fear of ChildBirth
Fear of childbirth is a common condition encountered during pregnancy. Women with fear of childbirth have reduced birth self-efficacy, and it leads to mental health problems in the prenatal and postnatal periods, reducing…
- Conditions
- Fear of Childbirth, Haptonomy, Mindfulness, Self-Efficacy
- Trial name
- NCT06956898
- Testing
- Mindfulness Training, Haptonomy Training
- Volunteers
- 225 people
- Sponsor
- Bayburt University
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.