Clinical trials: Fentanyl
Epidural, Analgesia
Epidural Analgesia and Delivery of Second Twin
Over an 8-year period, 124 twin pregnancies at gestational age ≥32 weeks with both twins presenting as a vertex and eligible for vaginal delivery were reviewed.
- Conditions
- Epidural, Analgesia, Labor Pain
- Trial name
- Epidural (NCT04608006)
- Testing
- Bupivacaine-fentanyl
- Where
- Egypt
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Abdelrady S Ibrahim, MD
Atrial Fibrillation, Electric Countershock
BIS-Guided Sedation Versus Standard Clinical Sedation During Elective Electrical Cardioversion for Atrial Fibrillation
Electrical cardioversion (ECV) is a standard procedure used to restore normal heart rhythm in patients with atrial fibrillation (AF) by delivering a brief electrical shock to the heart.
- Conditions
- Atrial Fibrillation, Electric Countershock, Deep Sedation
- Trial name
- BIS-ECV-RCT (NCT07569016)
- Testing
- BIS-guided propofol sedation, Clinical-guided propofol sedation
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istanbul University - Cerrahpasa
Atrial Flutter Typical, Heart Failure
Pulmonary Vein Isolation in Typical Atrial Flutter and Heart Failure
This study, called the PVI-AFL-HF Trial, investigates two treatments for patients with typical atrial flutter (AFL) and heart failure (HF).
- Trial name
- PVI-AFL-HF (NCT06817447)
- Testing
- Pulmonary vein isolation plus cavo-tricuspid isthmus ablation, Cavo-tricuspid isthmus ablation
- Volunteers
- 168 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Anesthesia, Anesthesia Intubation
Opioid-based Versus Opioid-free Endotracheal Intubation
The aim of this study will be to investigate the effect of opioid-free induction versus opioid-based induction on hemodynamic response and nociception level index during elective operations
- Conditions
- Anesthesia, Anesthesia Intubation, Opioid Use, Analgesic Non-narcotic
- Trial name
- NCT06464393
- Testing
- ketamine-lidocaine-dexmedetomidine, fentanyl
- Where
- Greece
- Volunteers
- 70 people
- Sponsor
- Aretaieion University Hospital
COPD
Morphine or Fentanyl for Refractory Dyspnea in COPD
Rationale: The most important complaint in severe COPD is dyspnea which is associated with a diminished exercise tolerance, reduced quality of life and can lead to anxiety and depression.
- Trial name
- MoreFoRCOPD (NCT03834363)
- Testing
- Fentanyl, Morphine Retard
- Where
- 10 sites in Netherlands
- Volunteers
- 59 people
- Sponsor
- Huib A.M. Kerstjens
Colon Cancer, IBS
Patient Satisfaction With Propofol for Out Patient Colonoscopy
The primary purpose of this study is to determine if patient satisfaction with propofol is better than with non-propofol anesthesia for outpatient colonoscopies.
- Conditions
- Colon Cancer, IBS, Polyps
- Trial name
- NCT02937506
- Testing
- Propofol, Fentanyl Plus Midazolam
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Mount Carmel Health System
Postoperative Pain
Thoracic Paravertebral Block in Pain Management After Renal Surgery
Objective: The objective of the study was to assess the usefulness of ThPVB in postoperative pain management after open renal resection surgery.
- Trial name
- NCT02840526
- Testing
- Paravertebral blockade (PVB), Sopodorm, Propofol WZF
- Where
- Poland
- Volunteers
- 58 people
- Sponsor
- Silesian University of Medicine
Postoperative Pain
Pectoralis and Serratus Nerve Blocks for Mastectomy: a Prospective, Randomized, Single-blind Trial
Pectoral nerve block provides a good alternative to epidural or paravertebral block with a lower risk for the patient and that is shown as an optimal anesthetic option with reduction in postoperative pain, anesthetic and opioid…
- Trial name
- NCT03966326
- Testing
- sevoflurane and fentanil, sevoflurane and fentanil plus PECS II block
- Where
- Brazil
- Volunteers
- 80 people
- Sponsor
- Hospital de Base
Myocardial Injury
Effects of Remote Ischemic PreConditioning in Off-pump Versus On-pump Coronary Artery Bypass Grafting(RIPCON)
Purpose Remote ischemic preconditioning (RIPC) with transient upper limb ischemia reduces myocardial injury in patients undergoing On-pump coronary artery bypass (CABG) surgery with cross-clamp fibrillation or blood cardioplegia…
- Trial name
- RIPCON (NCT01608984)
- Testing
- Remote ischemic preconditioning (RIPC), Coronary artery bypass grafting (CABG) without remote ischemic preconditioning protocol, Off-pump Coronary artery bypass surgery without remote ischemic preconditioning
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- Heinrich-Heine University, Duesseldorf
Post Operative Pain
Dexamethasone As Adjuvant for Pre - emptiveTransversusAbdominus Muscle Plane Block
Pain following bariatric surgery can be quite troublesome and prolongs recovery. Although laparoscopic bariatric surgery is minimally invasive and involves small incisions over the anterior abdominal wall, postoperative pain is…
- Trial name
- NCT06970548
- Testing
- Levobupivacaine
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Sohag University
Acute Pain Due to Trauma
Sublingual Versus Endovenous Fentanyl for Pain Treatment in Trauma Patients in the Emergency Room
The purpose of this study is to determine the non-inferiority of the efficacy of sublingual given fentanyl versus endovenous given fentanyl for patients in the emergency departement.
- Trial name
- NCT03080324
- Testing
- Fentanyl sublingual, Fentanyl ev
- Where
- Italy
- Volunteers
- 108 people
- Sponsor
- Azienda Sanitaria dell'Alto Adige
HELLP Syndrome
General Anesthesia Versus Spinal Anesthesia in Patients of HELLP Syndrome
Anesthesia for caesarian section in patients with HELLP syndrome is a challenge. Measures should be taken during caesarian delivery to guard against the maternal and fetal complications associated with HELLP syndrome.
- Trial name
- NCT03111446
- Testing
- Spinal Anesthesia, General Anesthesia
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Opioid Tolerance
Impact of Low Dose Naloxone on Fentanyl Requirements in Pediatric ICU Patients
Recently there has been an increased awareness in the need for adequate sedation and pain control for Pediatric Intensive Care Unit (ICU) patients.
- Trial name
- NCT00286052
- Testing
- Low Dose Naloxone
- Where
- United States
- Volunteers
- 128 people
- Sponsor
- University of Texas Southwestern Medical Center
Severe Chronic Pain
Matrifen® for Therapy of Severe Chronic Pain®
The aim of the study was to evaluate the efficacy and safety of Matrifen® in patients with severe and chronic pain who could only be sufficiently treated with opioid analgetics (WHO class 3).
- Trial name
- Matrix LQ (NCT00699335)
- Testing
- Fentanyl
- Where
- 1,235 sites in Germany
- Volunteers
- 5,308 people
- Sponsor
- Nycomed
Postoperative Sore Throat, Postoperative Cough
Effect of Lidocaine 1% and 2% in the Tube Cuff on Postoperative Sore Throat and Cough
Comparing the effect of different methods of endotracheal tube cuff inflation on the occurrence of a postoperative sore throat and cough (Air vs Lidocaine 1% vs Lidocaine 2%).
- Trial name
- ELIT (NCT03792776)
- Testing
- cuff inflation with air, cuff inflation with lidocaine 1%, cuff inflation with lidocaine 2%
- Volunteers
- 150 people
- Sponsor
- Ogarite Habib
Acute Pain, Wound Care
RCT: Fentanyl Plus Ketamine Versus Fentanyl Alone for Acute Burn Pain
The Ketamine for Acute Pain in Burns study is a randomized, double-blind, parallel group trial (RCT) with active control (usual care) contrasting the efficacy and safety of "Ketamine Plus Opiate-based usual care" (O+K) with the…
- Conditions
- Acute Pain, Wound Care, Posttraumatic Stress Disorder
- Trial name
- NCT03305055
- Testing
- ketamine, Fentanyl
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Johns Hopkins University
Epidural Anesthesia, Spinal Ultrasound
Ultrasound Versus Palpation for Epidural Catheterization
The study will assess the benefit of using spinal ultrasound before epidural catheter insertion compared to the conventional palpation technique in women undergoing cesarean section.
- Trial name
- NCT02410226
- Testing
- Double-space combined spinal-epidural anesthesia, Preprocedure spinal ultrasound
- Where
- Egypt
- Volunteers
- 110 people
- Sponsor
- Mansoura University
Sedation
Propofol Versus Alfentanil Versus Nitrous Oxide for Moderate Procedural Sedation
This is a clinical trial of propofol and alfentanil as agents for moderated procedural sedation in patients undergoing sedation in the emergency department (ED).
- Trial name
- NCT00997126
- Testing
- Propofol, Alfentanil
- Where
- United States
- Volunteers
- 126 people
- Sponsor
- Hennepin Healthcare Research Institute
Anesthesia
The Comparison of Different Administration Routes of Pediatric Premedication
The study purpose is to compare the effect of different Administration Routes of Pediatric Premedication (including oral administration, intramuscular injection, rectal perfusion, intranasal).
- Trial name
- NCT02313337
- Testing
- Oral administration, Intramuscular injection, Rectal perfusion
- Volunteers
- 80 people
- Sponsor
- Second Affiliated Hospital of Xi'an Jiaotong University
Opioid Use
Rectal Acetaminophen Use During Oocyte Retrievals to Reduce Post-Operative Opioid Utilization
The primary aim of this study is to evaluate the administration of rectal acetaminophen to current and standard anesthesia and analgesia protocol in oocyte retrievals would reduce postoperative utilization of opioids (Tylenol…
- Trial name
- NCT03732469
- Testing
- Acetaminophen, Fentanyl, Propofol
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- University of South Florida